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Effects of Panax Notoginseng Flos extract on Anti-oxidative, Anti-inflammatory and Acne skin (삼칠화 에탄올 추출물의 항산화, 항염증 활성 및 여드름 피부에 미치는 영향)

  • Kim, Song-Yi;Li, Shun-Hua
    • Journal of the Korean Applied Science and Technology
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    • v.35 no.1
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    • pp.43-54
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    • 2018
  • The purpose of this study is to observe how Panax Notoginseng Flos Ethanol Extract has anti-oxidant activity, cytotoxicity for skin cells, and anti-inflammatory effects and Cosmetics Panax Notoginseng Flos Ethanol Extract was applied to acne skin to analyze moisture, erythema, pores, and blackberries to identify potential as cosmetics material .According to the analysis, Panax Notoginseng Flos Ethanol Extract was found to have high contents of polyphenols and flavonoids and excellent DPPH radical scavenging activity. The extract had no significant cytotoxicity for Raw 264.7 cell and significantly inhibited the creation of NO induced LPS in Raw 264.7 cell so as to present anti-inflammatory effect. After applying an Panax Notoginseng Flos Ethanol Extract of 3% skin toner and spot Solutions to the skin of the skin of the acne for 3 weeks, Increased skin moisture, erythema, pores, black head count were found to be statistically signigicant, and reduced red spots were found in skin condition questions following management. Given the results, it is considered that Panax Notoginseng Flos Ethanol Extract is applicable as the ingredient of a functional cosmetic product that has low cytotoxicity for skin cells, high anti-oxidant activity, anti-inflammatory effect, and acne improvement effect.

Disease Severity of Angular Leaf Spot Disease by Different Inoculation Method and Eco-Friendly Control Efficacy in Strawberry. (접종방법에 따른 딸기모무늬병원균의 발병도 검증 및 친환경 방제 효과)

  • Kim, Da-Ran;Gang, Gun-hye;Cho, Hyun-ji;Yoon, Hae-Suk;Myoung, In Sik;kwak, Youn-Sig
    • The Korean Journal of Pesticide Science
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    • v.20 no.1
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    • pp.35-40
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    • 2016
  • Recently, bacterial angular leaf spot disease, caused by Xanthomonas fragariae, causes severe damage in strawberry production and its' export to other countries, since the pathogen has been classified as an A2 quarantine pathogen. Typical the Angular Leaf Spot (ALS) disease represent that water-soaked angular spots symptoms, bacteria ooze exudate under relatively high humidity condition and later the spot become reddish brown on the leaf surface. The pathogen disseminated by irrigation water, infected mother plant and farmer's hand. In this study, we reported that rubbing inoculation method showed more effective in the pathogen dissemination than infiltration with needles, regardless the strawberry cultivars. Additionally, Dichloroisocyanurate (NaDCC) treatment in commercial strawberry fields provided reliable efficiency to reduce the bacterial angular leaf spot disease incidency and severity.

Spatial Analysis of Colorectal Cancer Cases in Kuala Lumpur

  • Shah, Shamsul Azhar;Neoh, Hui-Min;Syed Abdul Rahim, Syed Sharizman;Azhar, Zahir Izuan;Hassan, Mohd Rohaizat;Safian, Nazarudin;Jamal, Rahman
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.3
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    • pp.1149-1154
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    • 2014
  • Background: In Malaysia, data from the Malaysian Health Ministry showed colorectal cancer (CRC) to be the second most common type of cancer in 2007-2009, after breast cancer. The same was apparent after looking at males and females cases separately. In the present study, the Geographic Information System (GIS) was employed to describe the distribution of CRC cases in Kuala Lumpur (KL), Malaysia, according to socio-demographic factors (age, gender, ethnicity and district). Materials and Methods: This retrospective review concerned data for patients diagnosed with colorectal cancer in the years 1995 to 2011 collected from the Wilayah Persekutuan Health Office, taken from the cancer notification form (NCR-2), and patient medical records from the Surgical Department, Universiti Kebangsaan Malaysia Medical Centre (UKMMC). A total of 146 cases were analyzed. All the data collected were analysed using ArcGIS version 10.0 and SPSS version 19.0. Results: Patients aged 60 to 69 years accounted for the highest proportion of cases (34.2%) and males slightly predominated 76 (52.1%), Chinese had the highest number of registered cases at 108 (74.0%) and staging revealed most cases in the 3rd and 4th stages. Kernel density analysis showed more cases are concentrated up in the northern area of Petaling and Kuala Lumpur subdistricts. Spatial global pattern analysis by average nearest neighbour resulted in nearest neighbour ratio of 0.75, with Z-score of -5.59, p value of <0.01 and the z-score of -5.59. Spatial autocorrelation (Moran's I) showed clustering significant with p<0.01, Z score 3.14 and Moran's Index of 0.007. When mapping clusters with hotspot analysis (Getis-Ord Gi), hot and cold spots were identified. Hot spot areas fell on the northeast side of KL. Conclusions: This study demonstrated significant spatial patterns of cancer incidence in KL. Knowledge about these spatial patterns can provide useful information to policymakers in the planning of screening of CRC in the targeted population and improvement of healthcare facilities to provide better treatment for CRC patients.

Nondestructive investigation of clay wall structure containing traditional mural paintings. - The clay walls having mural paintings housed in the protective building in Muwisa Temple, Kangjin, Jeollanamde Province - (전통 벽화의 토벽체 비파괴진단 조사연구 - 강진 무위사 벽화보존각내 벽화를 중심으로 -)

  • Chae, Sang-Jeong;Yang, Hee-Jae;Han, Kyeong-Soon
    • Journal of Conservation Science
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    • v.18 s.18
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    • pp.51-62
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    • 2006
  • This study, in order to do a nondestructive research on the mural walls kept in the protective house in Muwisa Temple, Kangjin, took four examinations; particle size analysis, XRD analysis, ultrasonic investigation, and thermo-infrared investigation. Component ratio of mural wall varied; clay of wall bodies consisted of gravel of 1.78 g, sand of 5.39 g, silt of 4.91 g and clay of 6.26 g. Ultrasonic velocity and one-axis compression strength tests done with eight mural-painted walls yield results as follows; the value of ultrasonic velocity ranged between 71.63 and 3610.11 m/s with the average of 417.44 m/s and on-axis compression strength ranged between 70.34 and $533.28kg/cm^2$ with the average of $83.23kg/cm^2$. The value increased in the order of Bosaldo(No.6)

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Analysis of Poly(3-Hydroxybutyrate) Granule-Associated Proteome in Recombinant Escherichia coli

  • Han Mee-Jung;Park Si-Jae;Lee Jeong-Wook;Min Byoung-Hoon;Lee Sang-Yup;Kim Soo-Jin;Yoo Jong-Shin
    • Journal of Microbiology and Biotechnology
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    • v.16 no.6
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    • pp.901-910
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    • 2006
  • Poly(3-hydroxybutyrate) [P(3HB)] is a microbial polyester intracellularly accumulated as distinct granules in numerous microorganisms as an energy and carbon storage material. Recombinant Escherichia coli harboring the heterologous P(3HB) biosynthesis genes accumulates large amounts of P(3HB) granules, yet the granule-associated proteins have not been identified. Therefore, this study reports on an analysis of the P(3HB) granule-associated proteome in recombinant E. coli. Fiye proteins out of 7 spots identified were found to be involved in functions of translation, heat-stress responses, and P(3HB) biosynthesis. Two of the major granule-associated proteins, IbpA/B, which are already known to bind to recombinant proteins forming inclusion bodies in E. coli, were further analyzed. Immunoblotting and immunoelectron microscopic studies with IbpA/B antibodies clearly demonstrated the binding and localization of IbpA/B to P(3HB) granules. IbpA/B seemed to play an important role in recombinant E. coli producing P(3HB) by stabilizing the interface between the hydrophobic P(3HB) granules and the hydrophilic cytoplasm. Thus, IbpA/B were found to act like phasins in recombinant E. coli, as they are the major proteins bound to the P(3HB) granules, affect the morphology of the granules, and reduce the amount of cytosolic proteins bound to the P(3HB) granules.

An Analysis on the Landscape Structure of Anuisamdong-Dongcheon in the 19th Century (19세기 안의삼동(安義三洞) 동천(洞天)의 경관구조 해석)

  • Kim, Dong-Hyun;Lee, Won-Ho
    • The Journal of the Korea Contents Association
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    • v.16 no.11
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    • pp.742-753
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    • 2016
  • This study aims to reproduce of Anuisamdong's landscape structure and improve the value of Scenic site. It was extract main spot from Geography book published by government in the 19th Century. And analyzed landscape architecture of Dongcheon. Extract main spot from Geography book published by government. Consequently, Hwarim-dong main spot 6 places, Simjin-dong main spot 9 places, and Wonhak-dong main spot 25 places were identified. Hwarim-dong's main spot was divided into 3 places of pavilion and scenery, respectively. Simjin-Dong's main spots was all that natural elements as a scenery. Wonhak-dong's main spot was the most elements of the Anuisamdong in geography book published by government. Hwarim-dong was pavilion-based scenery area complex, Simjin-dong was continues scenery spot along the valley, and Wonhak-dong was hybrid distribution that landscape structure. Each dongcheon in Anuisamdong was created a separate area through isolated geographical, visually for structure of collectively means. Also, a narrow entrance and enclosure topography are areas which arouse atmosphere of paradise. In addition, Aunuisamdong's landscape structure, which was previously divided into individual Dongcheon, was expanded into a single integrated landscape structure of Dongcheon. This is different from the general landscape development of common Dongcheon with the same starting and ending points and sightseeing routes.

Consideration Regarding the Breast Cancer Treatment Plan That Used Irregular Surface Compensator (ISC) (Irregular Surface Compensator (ISC)를 이용한 유방암치료계획에 관한 고찰)

  • Je, Young-Wan;Kim, Chan-Yong;Park, Heung-Deuk
    • The Journal of Korean Society for Radiation Therapy
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    • v.19 no.2
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    • pp.131-141
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    • 2007
  • Purpose: Try to compare dose distribution and lung dose of radiation treatment plan of the breast cancer that used Irregular Surface Compensator (ISC) and treatment plan that used a wedge filter. Materials and Methods: Established a treatment plan to be distributed over 95% of prescription dose (5,040 cGy) of the two tangent-half fields that used a wedge filter and ISC at a breast organization as made to breast cancer patient having an irregular surfaces after surgery. Compared high dose area and DVH, and verified a treatment plan as used film with rectangular phantom. Results: Maximum dose point in breast tissue appeared to 107.5% in case of tangent-half fields Tx plan that used a wedge filter, and lung volumes exposed above 20 Gy by 7.63%. In case of ISC, maximum dose point in breast tissue appeared to 106.4%, and lung volumes exposed above 20 Gy by 6.5%. The film measurement results that used phantom, 105$\sim$110% high dose region was distributed to the upper part and both edges of phantom. However in case of ISC, appeared by 100$\sim$105% dose conformity distribution. Conclusion: In general, the Irregular Surface Compensator (ISC) can improve the dose conformity of breast tissues, as well as reduced hot spots in the lung and in the breast. Such an advantage by using ISC technique is more beneficial for patients who have more irregular surfaces after surgery.

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Evaluation of Radiation effective dose by Naturally Radionuclides in the Soil of Busan (부산지역 토양 내 천연방사성핵종 분석 및 유효선량율 평가)

  • Kim, Jung-Hoon;Kim, Chang-Soo;Lim, Chang-Seon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.6
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    • pp.3658-3666
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    • 2014
  • The presence of $^{238}U$, $^{232}Th$ and $^{40}K$, which are naturally residing radionuclides, in the ordinary soil of Busan, the 2nd largest city in Korea, was anlayzed and the residents' radiation exposure to ordinary soil was evaluated. Regarding the measurement methods, to conduct a detailed analysis of the naturally residing radionuclides in the soil of Busan, this study divided the 16 administrative districts into a lattice structure with 3 spots, and collected a total of 48 soil samples (July 2012 and April 2013). ICP-MS was used to analyze the concentration of the radioactivity of $^{238}U$ and $^{232}Th$ in the soil, and a HpGe detector, a gamma ray detector, was used to analyze the radioactivity of $^{40}K$. The measurement values of this study were compared with the concentration of radioactivity of East Asian regions. The concentration of $^{238}U$ nuclides in Korea was lower than the mean, whereas the concentration of $^{232}Th$ and $^{40}K$ nuclides was higher than the mean. The higher mean concentrations of $^{232}Th$ and $^{40}K$ than the mean were attributed to the many granite areas that contain a great deal of naturally occurring radionuclides.

Multiple External Carotid Artery Aneurysms with Neurofibromatosis - Case Report - (신경섬유종을 동반한 다발성 외경동맥 동맥류 - 증 례 보 고 -)

  • Pyo, Sae Yeong;Kim, Moo Seong;Sim, Hong Bo;Lee, Sun Il;Jung, Yong Tae;Kim, Soo Chun;Sim, Jae Hong
    • Journal of Korean Neurosurgical Society
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    • v.29 no.9
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    • pp.1248-1254
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    • 2000
  • Multiple external carotid artery aneurysms with neurofibromatosis are rare. Trauma is the primary cause in the development of aneurysms of the external carotid artery. A 39-year-old female patient was referred to the emergency room because of a headache and a huge lump over the left temporo-parieto-occipital region. The physical examination revealed a huge round mass, $5{\times}15{\times}18cm$, in the left temporo-parieto-occipital region and low set left ear and multiple caf au lait spots in trunk and extremities. The external carotid artery angiography demonstrated multiple aneurysms arising from the superficial temporal artery and occipital artery. A MRI showed a huge hematoma on temporo-parieto-occipital region and postauricular mass suggested of subcutaneous neurofibroma. Embolization followed by surgical resections of those aneurysms and neighboring mass were performed and good result was obtained. We report our case with review of literature.

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An Empirical Study on the Establishment of a Korean Co-Prosperity Model (한국형 동반성장 모델구축에 관한 실증 연구: 포스코와 투자관련 중소기업과의 구축 사례를 중심으로)

  • Yun, Jeong-Keun;Lee, Hee-Je;Ryu, Mi-Jin;Lim, Jeong-Min;Seo, Won-Young
    • Journal of Distribution Science
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    • v.11 no.12
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    • pp.13-23
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    • 2013
  • Purpose - There is a dominant opinion that medium and small enterprises in the Korean economy have not developed qualitatively but only towards quantitative growth and, therefore, the unbalanced structure between large enterprises and those that are medium and small has worsened. In particular, this rapid industrialization causes after-effects such as polarization as well as anti-business sentiment, the collapse of the middle class, and hostility against the establishment. The consensus contends that it is difficult for Korea to be an advanced nation without resolving these problems. This paper attempts to suggest a co-prosperity model by limiting the focus to business relations with medium and small manufacturers (with regard to investment among the various co-prosperity institutions of POSCO). These co-prosperity institutions have been established in POSCO; however, it is thought that the development of a co-prosperity model regarding investment in medium and small manufacturers will help many needy investment manufacturers. Research design, data, and methodology - This study analyzes research on the co-prosperity model, using it to examine Korean cases and foreign cases. The co-prosperity model has been continuously extended but is determined to be seriously insufficient. The purpose of this study is to develop the Korean co-prosperity model by reinterpreting it in various aspects. In order to develop the Korean co-prosperity model, this study suggests the case of the establishment of the co-prosperity model by POSCO with medium and small manufacturers with regard to investment. This model is expected to be presented to many enterprises as the future co-prosperity model. Results - To date, analysis of the co-prosperity model itself and the co-prosperity model through the case of POSCO have been suggested. As empirical studies on co-prosperity in Korea are not sufficient, successful models of co-prosperity should be developed in various aspects in future. It is expected that through this study, medium and small manufacturers would have an opportunity to find various growth engines by actively using the cooperation platform and establishing optimized competitiveness of steel material through a steel business model. The ecosystem of enterprises may evolve and be healthier by making more joint products through productive business relationships between large enterprises and those that are medium and small. From the enterprises' ecosystem viewpoint, cooperation between such businesses rather than one-way support is identified as an essential element for the security of inter-competitiveness. Conclusions - Infrastructure should be established to form a dynamic industry ecosystem not by transient efforts in co-prosperity, but by an entire culture of co-prosperity across industries. In this respect, the leading role of public institutions needs to be intensified initially. In addition, the effects of co-prosperity should be extended to blind spots of policies such as third party companies and regions. A precise co-prosperity monitoring system should be established to continuously conduct and extend these efforts.