• 한국경제지리학회지
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• 제16권3호
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• pp.344-358
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• 2013

베트남이 세계 제2의 커피 생산국으로 도약하는 데에는 닥락(Dak Lak) 성(省)을 포함한 중부고원지대의 농업 발달이 있었으며 그러한 농업 발달에 연안지역에서 내륙고원지대로의 이주가 중요한 역할을 수행하였다. 기존 연구는 이러한 이주의 중요성을 인지하면서 계획 이주와 자발적 이주로 나누어 논의를 전개해 왔다. 하지만 이들 연구는 계획이주와 자발적 이주 간의 연계 관계를 명확히 파악하지 못했으며 이들의 연계 관계가 커피의 생산 현장이라 할 수 있는 꼬뮨 단위에서 차별적으로 구현되었는지 밝히지 못했다. 이에 본 연구는 닥락 성으로의 이주 흐름을 통계자료로 분석하고 Ea H'Ding 꼬뮨과 Doan Ket 꼬뮨을 사례지역으로 선정하여 전문가와의 면담 그리고 농가 설문과 면담을 통해 이주 과정을 비교 분석하였다. 그 결과 닥락 성 스케일에서 계획 이주가 초기에는 많았다가 점차 감소하였으나, 대신 자발적 이주가 점차 증가하면서 꾸준한 인구 유입이 이루어져 이 지역이 커피 생산지로 발돋움할 수 있었다. 하지만 커피 생산의 구체적 현장이라 할 수 있는 소지역 스케일에서는 계획 이주와 자발적 이주 간 연계 관계가 서로 다른 민족 구성, 정주 시기, 정부 개발 프로그램, 이주민 폭증 시기를 갖는 꼬뮨별로 상이하게 구현되었음이 밝혀져 국지적 맥락의 중요성을 확인할 수 있었다.

• Journal of Microbiology and Biotechnology
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• 제32권6호
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• pp.792-799
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• 2022

As a vital problem in reproductive health, recurrent spontaneous abortion (RSA) affects about 1% of women. We performed this study with an aim to explore the molecular mechanism of interleukin-23 (IL-23) and find optimal or effective methods to improve RSA. First, ELISA was applied to evaluate the expressions of IL-23 and its receptor in HTR-8/SVneo cells after IL-23 treatment. CCK-8, TUNEL, wound healing and transwell assays were employed to assess the proliferation, apoptosis, migration and invasion of HTR-8/SVneo cells, respectively. Additionally, the expressions of apoptosis-, migration-, epithelial-mesenchymal transition- (EMT-) and p38 MAPK signaling pathway-related proteins were measured by western blotting. To further investigate the relationship between IL-23 and p38 MAPK signaling pathway, HTR-8/SVneo cells were treated for 1 h with p38 MAPK inhibitor SB239063, followed by a series of cellular experiments on proliferation, apoptosis, migration and invasion, as aforementioned. The results showed that IL-23 and its receptors were greatly elevated in IL-23-treated HTR-8/SVneo cells. Additionally, IL-23 demonstrated suppressive effects on the proliferation, apoptosis, migration, invasion and EMT of IL-23-treated HTR-8/SVneo cells. More importantly, the molecular mechanism of IL-23 was revealed in this study; that is to say, IL-23 inhibited the proliferation, apoptosis, migration, invasion and EMT of IL-23-treated HTR-8/SVneo cells via activating p38 MAPK signaling pathway. In conclusion, IL-23 inhibits trophoblast proliferation, migration, and EMT via activating p38 MAPK signaling pathway, suggesting that IL-23 might be a novel target for the improvement of RSA.

• 대한핵의학회지
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• 제33권2호
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• pp.184-188
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• 1999

Although cerebrospinal fluid leakage is suggested as one of the causes of spontaneous intracranial hypotension, only a few cases with direct evidence of cerebrospinal fluid leakage on radionuclide cisternography have been reported in the literature. Indirect evidences of cerebrospinal fluid leakage such as early visualization of the soft tissue and bladder or delayed migration of radiotracer have been observed in most patients with spontaneous intracranial hypotension. We report a case of spontaneous intracranial hypotension in which cerebrospinal fluid leakage was directly demonstrated by early dynamic imaging of spine on radionuclide cisternography. We suggest that early dynamic imaging of spine is an important adjunctive procedure in detecting cerebrospinal fluid leakage in patients with spontaneous intracranial hypotension.

• EDISON SW 활용 경진대회 논문집
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• 제4회(2015년)
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• pp.163-166
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• 2015

Intramolecular energy migration in a cyclic porphyrin array is spontaneous transfer of energy from one excited site to another. Since the efficiency of energy migration is inversely proportional to distance, the energy migration is occurred on their adjacent sites more often than distant ones. Therefore, the energy migration in the cyclic porphyrin array is largely dependent on their conformational characters. However, evaluation of conformational information by means of experimental tools is ambiguous since their limited resolution. In this work, we calculate the internal angle and distance distributions of cyclic porphyrin arrays using molecular dynamics simulations to obtain conformational information. To evaluate the angle and distance distributions respect to molecular size, we constructed molecules with n porphyrin dimers (n=1,3,7) in implicit solvent environment. Performing molecular dynamics simulations, we modulated alkyl groups to investigate additional conformational effects of the system.

• Journal of Korean Neurosurgical Society
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• 제47권3호
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• pp.213-216
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• 2010

Spontaneous intracerebral hemorrhage (ICH) is a common condition that often leads to death or disability. Accurate prediction of the outcome and decisions regarding the treatment of ICH patients are important issues. We report a case of thalamic hemorrhage with an intraventricular hemorrhage that was suddenly migrated into the third and fourth ventricles in its entirety 8 hours after symptom onset. To our knowledge, this case is the first report of spontaneous migration of thalamic ICH into ventricles, and we suggest a possible mechanism for this case with a brief review of the literature.

• Bulletin of the Korean Chemical Society
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• 제23권1호
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• pp.9-10
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• 2002

• IMMUNE NETWORK
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• 제5권4호
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• pp.247-251
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• 2005

Background: Natural killer (NK) cells are CD3 (-) CD14 (-) CD56 (+) lymphocytes. They play an important role in the body's innate immune response. They can induce spontaneous killing of cancer cells or virus-infected cells via the Fas/Fas ligand or the granzyme/perforin systems. The corticotropin-releasing hormone (CRH) is an important regulator for the body's stress response. It promotes proliferation and migration of various cancer cells through the CRH type 1 receptor under stress, and also inhibits NK or T cell activity. However, the relationship of CRH and NK cell migration to the target has not been confirmed. Herein, we study the effect of CRH on NK cell migration. Methods: We used the human NK cell line, NK-92MI, and tested the expression of CRH receptor type 1 on NK-92MI by RT-PCR. This was to examine the effect of CRH on tumor and NK cell migration, thus NK cells (NK-92MI) were incubated with or without CRH and then each CRH treated cell's migration ability compared to that of the CRH untreated group. Results: We confirmed that CRH receptor type 1 is expressed in NK-92MI. CRH can decrease NK cell migration in a time-/dose-dependent manner. Conclusion: These data suggest CRH can inhibit NK cell migration to target cells.

• 대한핵의학회지
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• 제32권6호
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• pp.482-489
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• 1998

목적: 방사성 동위원소 뇌조조영술은 자발성 두 개 내 저압환자의 체위성 두통과 저뇌척수압의 병태생리를 이해하는데 도움을 줄 수 있다. 저자들은 이 질환의 방사성 동위원소 뇌조조영술의 특징적인 소견을 알아보고자 하였다. 대상 및 방법: 자발성 두개내 저압으로 진단되어 방사성 동위원소 뇌조조영술을 시행한 15명을 대상으로 하였다. 뇌조조영술은 Tc-99m DTPA 111-222 MBq를 요추천자를 통해 지주막하강에 투여한 후 감마카메라로 30분부터 2시간 이내에 방광을 포함한 요추부와 경흉추부의 전면상과 측면상을 얻었고, 4, 6, 24시간에 두부와 경흉추부의 전면상과 측면상을 얻었다. 방광 내 방사성 추적자의 조기 배설유무, 척수강 내 방사성의 이동속도, 연조직 섭취정도, 그리고 대뇌궁융부로의 이동 지연 등을 분석하였다. 결과: 방사성 동위원소 뇌조조영술 소견은 대뇌궁융부로의 방사성 추적자의 이동지연(14/15), 연조직의 섭취증가(11/15), 방광 내 방사성 추적자의 조기 출현(13/13) 등이 있었고 뇌척수액의 누출을 시사하는 척수경막강 주위의 방사성 추적자의 국소 집적도 4예에서 있었다. 결론: 방사성 추적자의 이동 지연과 연조직의 섭취증가 및 방광 내 방사성 추적자의 조기 출현 등이 특징적으로 관찰되었고, 이러한 뇌조조영술 소견은 자발성 두개 내 저압의 주된 병태생리가 뇌척수액의 누출임을 시사하는 것으로 판단되었으며, 방사성 추적자 이동의 역동적 측면을 잘 평가하기 위해서는 방광과 연조직을 포함한 30분 영상과 다발적인 연속영상을 획득하는 것이 필요하다고 생각된다.

• Journal of Korean Neurosurgical Society
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• 제46권4호
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• pp.409-412
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• 2009

There are several mechanisms for the dissemination of lipid material from a mature teratoma into the subarachnoid space or ventricles, including iatrogenic or traumatic rupture, but spontaneous rupture of a mature teratoma is rare We report the spontaneous rupture of a spinal mature teratoma into the subarachnoid space and ventricles. However, at surgery, there was no definite evidence of rupture into the perimedullary cerebrospinal fluid. We postulate that the central canal could be a migration pathway for ruptured material into the brain.

• Journal of East-Asian Urban History
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• 제1권
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• pp.7-24
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• 2019

A. J. Toynbee published a book called Travel to China(1931) after traveling around the Asian continent in 1929. The book mostly focuses on Japan, China and the relationship between the two countries. Toynbee visited major cities in Japan and China by train. Most of the Japanese cities he saw were turning into modern cities in the process of spontaneous modernization mixed with its tradition. On the other hand, Chinese cities that he visited showed him various characteristics, including traditional, colonial, or semi-colonial cities. The modern cities of Japan and China in the late 1920s were transformed into various aspects under the influence of tradition, spontaneous modernization, colonial or anti-colonial modernization. How did Toynbee look at cities in East Asia? How did he recognize the relationship between tradition, modernization and colonization while visiting this area? Toynbee emphasizes the weight and influence of tradition especially in the development of modern cities in Japan and China. So, are modern European cities born out of their own traditions? Modern cities everywhere in the East and West were newly developed under the influence of tradition. Toynbee's attitude, which emphasizes especially its tradition in the modern cities of East Asia, seems to reflect his Orientalistic view.