• 대한토목학회논문집
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• 제36권3호
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• pp.349-359
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• 2016

공용 중인 교량의 버페팅 응답을 해석적으로 평가하기 위해서는 교량 현장의 난류강도, 난류 스펙트럼, 조도계수, 거스트 계수 등 풍하중에 대한 분석이 우선되어야 하고, 해석 결과는 정적 공기력 계수, 플러터계수, 구조 감쇠비, 공기역학적 감쇠비, 고유 진동수 등 여러 변수에 의해 영향을 받는다. 본 논문에서 대상으로 한 교량은 32년째 공용 중에 있는 교량으로써 교량 주변의 지형조건은 설계 및 시공 당시에 비해 많은 변화가 발생하였으며 최근 기후 변화로 인한 풍 환경 역시 큰 변화가 있다. 이러한 이유로 대상교량에서 실측한 풍속 데이터를 분석하여 난류강도, 난류길이, 지표조도계수, 풍속 스펙트럼 등 교량 현장의 풍하중을 평가하였다. 교량 주변의 풍환경 평가 결과, 대상 교량은 해상교량임에도 불구하고 지표조도구분 II의 특성을 나타내고 있었다. 또한 실측한 구조물의 가속도, 변위 응답 데이터를 통해 대상교량의 감쇠비, 정적 공기력 계수, 고유진동수를 평가하여 계측기반 버페팅 해석 변수를 산정하였다. 계측데이터 기반의 해석 변수와 케이블강교량설계지침에 제시된 해석 변수를 적용하여 총 4가지 경우에 대한 버페팅 해석을 수행하였으며, 그 결과 10분 평균 풍속 25m/s이하에서 측정된 버페팅 응답과 계측 기반 해석 변수를 적용한 해석 응답이 가장 잘 일치함을 확인하였고, 계측 풍속과 Gumbel 확률분포를 이용하여 추정한 200년 재현기대 풍속인 45m/s에서의 버페팅 응답을 제시하였다.

• 대한토목학회논문집
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• 제32권5B호
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• pp.321-329
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• 2012

파향이 약간 다르게 진행하는 두 규칙파는 비선형적 상호작용에 기인하여 파봉선이 벌집구조와 유사한 모습을 갖는 현상이 발생하고, 벌집구조 모양의 파봉선 사이에 일정하게 파랑에너지가 매우 낮게 유지되는 노드선 영역이 생성된다. 이러한 파봉선 벌집구조 모양이 해변에 형성되면, 해안선 직각방향으로 생성되는 노드선 영역을 통하여 이안류가 발달하게 된다. 본 연구에서는 해변가에 형성되는 벌집구조 파봉선 현상이 해운대에서 발생하는 이안류의 주요한 메카니즘임을 확인하기 위하여, Boussinesq 파랑모형을 이용하여 일방향 규칙파에 의한 해운대 연안흐름의 수치해석을 수행하고 이를 분석하였다. 그 결과, 해운대 앞바다의 해저천퇴에 따른 파랑굴절로 파향이 서로 약간 다른 파랑들이 해안에 전파되고, 이에 따라 벌집구조가 형성되어 노드영역을 따라 이안류가 매우 잘 발달함을 확인할 수 있었다. 또한, 일정한 파고와 주기를 갖는 다양한 폭의 스펙트럼에 따른 불규칙파 수치모의를 수행하므로, 폭이 넓은 스펙트럼 파랑조건보다 규칙파에 가까운 폭이 좁은 스펙트럼의 파랑조건에서 이안류가 더 잘 발달하는 것을 확인하였다.

• Journal of Advanced Marine Engineering and Technology
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• 제24권6호
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• pp.61-69
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• 2000

Indium-Tin Oxide (ITO) films were prepared on the commercial glass substrate by the Magnetron Sputtering method. The target was a 90wt.% $In_2O_3$-10wt.% $SnO_2$with 99.99% purity. The ITO films deposited by changing the partial pressure of oxygen gas ($O_2$/(Ar+$O_2$)) of 2, 3 and 5% as well as by changing the substrate temperature of $300^{\circ}C$ or $500^{\circ}C$. The influence of substrate pre-annealing and pre-cleaning on the quality of ITO film were examined, in which the substrate temperature was $500^{\circ}C$ and oxygen partial pressure was 3%. The characteristics of films were examined by the 4-point probe, Hall effect measurement system, SEM, AFM, Spectrophotometer, and X-ray diffraction. The optimum ITO films have been obtained when the substrate temperature is $500^{\circ}C$ and oxygen partial pressure is 3%. At optimum condition, the film showed transmittance of 81%, sheet resistivity of $226\Omegatextrm{cm}^2$, resistivity($\rho$) of $5.4\times10^{-3}\Omega$cm, carrier concentration of $1.0\times10^{19}cm^{-3}$, and carrier mobility of $150textrm{cm}^2$Vsec. From XRD spectrum, c(222) plane was dominant in the case of substrate temperature at $300^{\circ}C$, without regarding to oxygen partial pressure. However, in the case of substrate temperature at $500^{\circ}C$, c(400) plane was grown together with c(222) plane, only for oxygen partial pressure of 2 and 3%. In both case of chemical and ultrasonic cleaning without pre-annealing the substrate, it showed much almost same sheet resistivity, resistivity($\rho$), transmittance, carrier concentration, and carrier mobility. In case of $500^{\circ}C$/60min pre-annealing before ITO film deposited, both transimittance and carrier mobility are better than no pre-annealing, because pre-annealing is supposed to remove alkari ions diffusion from substrate. ITO film deposited on the Corning 0080 sybstrate showed a little bit better sheet resistivity, resistivity($\rho$), transimittance, carrier concentration than the film deposited on commercial glass. But no differences between Corning substrate and pre-annealed commercial glass substrate are found.

• 한국의학물리학회지:의학물리
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• 제9권4호
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• pp.259-266
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• 1998

코발트-60 근접조사선원을 대체할 Ir-l92 선원주변의 2차원적 선량분포를 얻기 위하여, 조사선량률과, 조직감쇠계수를 구하였다. 조직감쇠계수는 선원에서 20 cm 지점까지 실험식을 구하였다. ？보기 방사능은 조사선량상수를 사용하여 결정하였으며, 2.5mm 직경에 두께 2.5 mm 의 선원은 조직선량을 정하기 위해 선원을 4401 개로 분할하여 선원 자체의 흡수효과와 ？슐벽의 차폐 효과와 조직감쇠계수를 적용하였다. 조직감쇠계수는 4차식을 사용하여 1% 오차범위내에서 실험값을 얻을 수 있었으며, Meisberger 상수는 선원에서 많이 떨어질수록 오차가 커서, 10 cm 위치서 7%, 20 cm 에서 33%의 오차를 발견할 수 있었으나, 겉보기방사능과 선원모양 및 크기가 달라 다른 결과를 가져올 수 있다고 본다. 발표된 Ir-192 선원의 에너지스펙트럼을 이용한 선량률상수는 절삭에너지 10 keV인 경우 4.69 R$cm^2$/mCi-hr을 얻었으며 Air Kerma는 0.973 을 구하였다. 이 실험에서 고안 선원의 분할선원에 의한 선원자체흡수와 ？슐벽에 의한 감쇠는 실선원의 54.6%가 겉보기방사능으로 나타남을 알 수 있었으며, 선량계획에 이용하기 위해 단위 ？보기 방사능에 대한 2차원적 선량표를 준비함으로써 기하학적선량과 선량 비등방성을 쉽게 이용할 수 있도록 하였다.

• Investigative Magnetic Resonance Imaging
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• 제21권1호
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• pp.1-8
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• 2017

Purpose: To investigate the exchange and redistribution of hyperpolarized $^{13}C$ metabolites between different pools by temporally analyzing the relative fraction of dual $T_2{^*}$ components of hyperpolarized $^{13}C$ metabolites. Materials and Methods: A dual exponential decay analysis of $T_2{^*}$ is performed for [1-$^{13}C$] pyruvate and [1-$^{13}C$] lactate using nonspatially resolved dynamic $^{13}C$ MR spectroscopy from mice brains with tumors (n = 3) and without (n = 4) tumors. The values of shorter and longer $T_2{^*}$ components are explored when fitted from averaged spectrum and temporal variations of their fractions. Results: The $T_2{^*}$ values were not significantly different between the tumor and control groups, but the fraction of longer $T_2{^*}$ [1-$^{13}C$] lactate components was more than 10% in the tumor group over that of the controls (P < 0.1). The fraction of shorter $T_2{^*}$ components of [1-$^{13}C$] pyruvate showed an increasing tendency while that of the [1-$^{13}C$] lactate was decreasing over time. The slopes of the changing fraction were steeper for the tumor group than the controls, especially for lactate (P < 0.01). In both pyruvate and lactate, the fraction of the shorter $T_2{^*}$ component was always greater than the longer $T_2{^*}$ component over time. Conclusion: The exchange and redistribution of pyruvate and lactate between different pools was investigated by dual component analysis of the free induction decay signal from hyperpolarized $^{13}C$ experiments. Tumor and control groups showed differences in their fractions rather than the values of longer and shorter $T_2{^*}$ components. Fraction changing dynamics may provide an aspect for extravasation and membrane transport of pyruvate and lactate, and will be useful to determine the appropriate time window for acquisition of hyperpolarized $^{13}C$ images.

• Asian Pacific Journal of Cancer Prevention
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• 제15권2호
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• pp.925-928
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• 2014

Background: Gestational trophoblastic neoplasia (GTN) is a spectrum of disease with abnormal trophoblastic proliferation. Treatment is based on FIGO stage and WHO risk factor scores. Patients whose score is 12 or more are considered as at extremely high risk with a high likelihood of resistance to first line treatment. Optimal therapy is therefore controversial. Objective: This study was conducted in order to summarize the regimen used for extremely high risk or resistant GTN patients in our institution the in past 10 years. Materials and Methods: All the charts of GTN patients classified as extremely high risk, recurrent or resistant during 1 January 2002 to 31 December 2011 were reviewed. Criteria for diagnosis of GTN were also assessed to confirm the diagnosis. FIGO stage and WHO risk prognostic score were also re-calculated to ensure the accuracy of the information. Patient characteristics were reviewed in the aspects of age, weight, height, BMI, presenting symptoms, metastatic area, lesions, FIGO stage, WHO risk factor score, serum hCG level, treatment regimen, adjuvant treatments, side effects and response to treatment, including disease free survival. Results: Eight patients meeting the criteria of extremely high risk or resistant GTN were included in this review. Mean age was 33.6 years (SD=13.5, range 17-53). Of the total, 3 were stage III (37.5%) and 5 were stage IV (62.5%). Mean duration from previous pregnancies to GTN was 17.6 months (SD 9.9). Mean serum hCG level was 864,589 mIU/ml (SD 98,151). Presenting symptoms of the patients were various such as hemoptysis, abdominal pain, headache, heavy vaginal bleeding and stroke. The most commonly used first line chemotherapeutic regimen in our institution was the VAC regimen which was given to 4 of 8 patients in this study. The most common second line chemotherapy was EMACO. Adjuvant radiation was given to most of the patients who had brain metastasis. Most of the patients have to delay chemotherapy for 1-2 weeks due to grade 2-3 leukopenia and require G-CSF to rescue from neutropenia. Five form 8 patients were still survived. Mean of disease free survival was 20.4 months. Two patients died of the disease, while another one patient died from sepsis of pressure sore wound. None of surviving patients developed recurrence of disease after complete treatment. Conclusions: In extremely high risk GTN patients, main treatment is multi-agent chemotherapy. In our institution, we usually use VAC as a first line treatment of high risk GTN, but since resistance is quite common, this may not suitable for extremely high risk GTN patients. The most commonly used second line multi-agent chemotherapy in our institution is EMA-CO. Adjuvant brain radiation was administered to most of the patients with brain metastasis in our institution. The survival rate is comparable to previous reviews. Our treatment demonstrated differences from other institutions but the survival is comparable. The limitation of this review is the number of cases is small due to rarity of the disease. Further trials or multicenter analyses may be considered.

• 한국응용과학기술학회지
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• 제37권5호
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• pp.1138-1150
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• 2020

본 연구는 다양한 식물 추출물들이 가지고 있는 항산화 능력과 자외선 차단 능력을 동시에 조사하여 추후, 항산화 효과가 있는 자외선 차단제를 개발하고자 실험을 실시하였다. 먼저 33종의 식물 추출물들의 자외선 차단 능력을 조사하기 위하여 자외선 파장 280~400nm 사이의 흡광도 스펙트럼을 조사하고, 이로부터 우수한 자외선 차단능력을 갖는 것으로 보이는 식물 추출물로 황금, 홉, 녹차, 감초, 방풍, 칡, 그라비올라, 밀싹, 상백피, 가시박, 옻, 등 11종을 선별하였다. 선별된 식물추출물의 총 폴리페놀 함량, 총 플라보노이드 함량, DPPH radical 소거 활성을 측정하여 항산화 활성 정도를 살펴보고, 이로부터 다시 자외선 차단 능력과 항산화 활성이 동시에 우수한 식물 추출물로 황금, 홉, 감초추출물 3종을 선정하였다. 선정된 황금, 홉, 감초추출물을 1:1:1로 혼합하여 겔 형태의 크림을 제조하고, 이 크림이 가지는 자외선 차단 효과를 배양된 세포에 자외선을 조사하였을 때 보여주는 세포 손상 방어 효과를 측정하는 방법으로 결정하였다. 연구 결과, 선정된 식물 추출물의 혼합물은 자외선 흡수 능력에서 상호 보완적이며, 세포 손상 방어 효과도 증가하였음을 확인하였다. 이와 같은 결과를 통하여 다양한 식물 추출물들이 가지고 있는 항산화 능력과 자외선 차단 능력을 동시에 결정할 경우 항산화 효과가 있는 자외선 차단제 개발이 가능함을 확인하였다.

• 미술이론과 현장
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• 제7호
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• pp.125-163
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• 2009

The artworks of Socialist Realism of the former Soviet Union, with the beginning of the 21st century, are gaining a new attention from art collectors. One reason for this might consist in the fact that relevant art pieces exemplify the ways in which they visualize ideas on the basis of their high-profile art tradition and also in which they integrate their utopian ideals with mysticism. These aspects of the Soviet art goes far beyond the wide-spread assumption that their art, as a means of propaganda, principally represents a political allegiance to the system. With Stalin coming into power in the 1930s, the artistic trend of Socialist Realism obtained a nationwide sympathy and support from people, giving birth to a new art which essentially corresponded to the demands of the political power. An official art current of the USSR over the period from the 1930s to 1950s, Socialist Realism was in tandem with the Communist commitment to the party and popularity, symbolizing a loyalty to the cause. It was thus characterized by plainness and lucidity so that ordinary people could gain easy access to art. Its salient feature, over an entire range of art, was an optimistic pursuit of a utopian dream. Therefore, it tallied with the popular sentiment for a Communist paradise, giving form to their beliefs in human agency working at the materialist world and also to such abstract concepts as force, fitness, and beauty by adding even mythical ideals. Its main subject matter includes harvest feasts of collective farms, imaginary socialist cities, grand marches of heroic laborers and in this way it served as a propaganda for a sacred utopia of socialist totalitarianism. On the other end of the spectrum, however, rose the second camp of art, which put an emphasis on bona-fide artistic activities of plastic art and on an artist's personal expression and freedom, as opposed to the surface optimism of Socialist Realism. Central to the Russian Avant Garde art, which prized the above-mentioned values, were Malevich's Geometric Abstraction and A. Rodchenko's Constructivism. Furthermore, in the transitional era of the late 20th century and the 21st century it was recognized that film art or electronic media art, rather than traditional genre of paintings, would function as a more efficient way of propaganda. These new genres were made possible by ridiculing the stereotypes of the Russian lifestyle and also by ignoring ethical or professional dimensions of artworks. That is, they reinvented themselves into a sort of field art, seemingly degrading the quality of artworks and transforming them into artifacts or simulacres in the very sense of post-modernism. The advent of the new era brought about the formation and occupation of pop culture of the younger generations, calling into question the idea of art as the class-determined. It also increased the attention to field art, which extensively found way to modern art centers, galleries, and exhibition projects. It can be stated that this was a natural outcome of human nature.

• 한국자기공명학회논문지
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• 제5권2호
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• pp.99-109
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• 2001

Authors investigated neuronal changes of local cellular metabolism in the cerebral lesions of Parkinsonian symptomatic side between before and after stereotactic neurosurgery by follow-up 1H magnetic resonance spectroscopy (MRS). Patients with Parkinson's disease (PD) (n = 15) and age-matched normal controls (n = 15) underwen MRS examinations using a stimulated echo acquisition mode (STEAM) pulse sequence that provided 2${\times}$2${\times}$2 ㎤ (8ml) volume of interest in the regions of substantia nigra, thalamus, and lentiform nucleus. Spectral parameters were 20 ms TE, 2000 ms TR, 128 averages,2500 Hz spectral width, and 2048 data points. Raw data were processed by the SAGE data analysis package (GE Medical Systems). Peak areas of N-acetylaspartate (NAA), creatine (Cr), choline-containing compounds (Cho), inositols (Ins), and the sum (Glx) of glutamate and GABA were calculated by means of fitting the spectrum to a summation of Lorentzian curves using Marquardt algorithm. After blindly processed, we evaluated neuronal alterations of observable metabolite ratios between before and after stereotactic neurosurgery using Pearson product-moment analysis (SPSS, Ver. 6.0). A significant reduction of NAA/Cho ratio was observed in the cerebral lesion in substantia nigra of PD patient related to the symptomatic side after neurosurgery (P : 0.03). In thalamus, NAA/Cho ratio was also significantly decreased in the cerebral lesion including the electrode-surgical region (P : 0.03). A significant reduction of NAA/Cho ratio in lentiform nucleus was not oberved, but tended toward significant reduction after neurosurgery (P = 0.08). In particular, remarkable lactate signal was noted from the surgical thalamic lesions of 6 among 8 patients and internal segments of globus pallidus of 6 among 7 patients, respectively. Significant metabolic alterations of NAA/Cho ratio might reflect functional changes of neuropathological processes in the lesion of substantia nigra, thalamus, and lentiform nucleus, and could be a valuable finding fur evaluation of Parkinson's disease after neurosurgery. Increase of lactate signals, being remarkable in surgical lesions, could be consistent with a common consequence of neurosurgical necrosis. Thus, IH MRS could be a useful modality to evaluate the diagnostic and prognostic implications fur Parkinsons disease after functional neurosurgery.

• 한국멀티미디어학회논문지
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• 제13권5호
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• pp.710-721
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• 2010

최근, 모바일 임베디드 기술의 발달로 인하여 일반 사용자가 멀티미디어콘텐츠를 손쉽게 제작하고 이를 GIS(geographic information system) 웹 맵과 연동하여 다양하게 응용 하는 매쉬업 서비스가 웹 2.0 인터넷환경에서 활발히 서비스되고 있다. 그러나 매쉬업 서비스에서 다뤄지는 콘텐츠는 웹 맵과 연동되어 GPS 좌표 정보와 같은 사용자의 공간상 이동 경로를 포함하는 새로운 형태의 콘텐츠인데 반해 해당 콘텐츠에 대한 지적 재산 및 사생활 보호를 위한 방법이 아직까지 존재하지 않는다. 본 논문에서는 GIS 웹 맵 매쉬업 서비스에서 사용자 사생활 보호와 불법 촬영자 추적을 위하여 모바일 카메라 폰을 통해 촬영된 이미지 내에 위치 정보와 사용자 정보를 은닉하는 기법을 제안하고 이를 스마트 폰에 구현하였다. 위치정보에 대하여 좌표 값의 오차 범위를 최소화하기 위해 비트 가중치를 고려하여 색차신호에 은닉하였으며, 부정 촬영자를 추적하기 위해 장비 고유번호, 전화번호, 촬영날짜 정보를 휘도신호에 대해 주파수도메인 상에 은닉하였다. 실험 결과 위치정보 삽입에서 다양한 영상처리에 대해서 신뢰할 수 있는 오차범위를 가짐을 확인할 수 있었고, 포맷변환 시에도 위치정보를 정확히 추출하였다. 휘도신호의 정보은닉 실험 결과 공격에 의해 훼손된 영상에 대하여 유사도 패턴 매칭을 통하여 삽입한 정보를 모두 검출 하였다.