• Title/Summary/Keyword: spectrum

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Metabolic Changes in Patients with Parkinson's Disease after Stereotactic Neurosurgery by Follow-up 1H MR Spectroscopy

  • Choe, Bo-Young;Baik, Hyun-Man;Chun, Shin-Soo;Son, Byung-Chul;Kim, Moon-Chan;Kim, Bum-Soo;Lee, Hyoung-Koo;Suh, Tae-Suk
    • Journal of the Korean Magnetic Resonance Society
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    • v.5 no.2
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    • pp.99-109
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    • 2001
  • Authors investigated neuronal changes of local cellular metabolism in the cerebral lesions of Parkinsonian symptomatic side between before and after stereotactic neurosurgery by follow-up 1H magnetic resonance spectroscopy (MRS). Patients with Parkinson's disease (PD) (n = 15) and age-matched normal controls (n = 15) underwen MRS examinations using a stimulated echo acquisition mode (STEAM) pulse sequence that provided 2${\times}$2${\times}$2 ㎤ (8ml) volume of interest in the regions of substantia nigra, thalamus, and lentiform nucleus. Spectral parameters were 20 ms TE, 2000 ms TR, 128 averages,2500 Hz spectral width, and 2048 data points. Raw data were processed by the SAGE data analysis package (GE Medical Systems). Peak areas of N-acetylaspartate (NAA), creatine (Cr), choline-containing compounds (Cho), inositols (Ins), and the sum (Glx) of glutamate and GABA were calculated by means of fitting the spectrum to a summation of Lorentzian curves using Marquardt algorithm. After blindly processed, we evaluated neuronal alterations of observable metabolite ratios between before and after stereotactic neurosurgery using Pearson product-moment analysis (SPSS, Ver. 6.0). A significant reduction of NAA/Cho ratio was observed in the cerebral lesion in substantia nigra of PD patient related to the symptomatic side after neurosurgery (P : 0.03). In thalamus, NAA/Cho ratio was also significantly decreased in the cerebral lesion including the electrode-surgical region (P : 0.03). A significant reduction of NAA/Cho ratio in lentiform nucleus was not oberved, but tended toward significant reduction after neurosurgery (P = 0.08). In particular, remarkable lactate signal was noted from the surgical thalamic lesions of 6 among 8 patients and internal segments of globus pallidus of 6 among 7 patients, respectively. Significant metabolic alterations of NAA/Cho ratio might reflect functional changes of neuropathological processes in the lesion of substantia nigra, thalamus, and lentiform nucleus, and could be a valuable finding fur evaluation of Parkinson's disease after neurosurgery. Increase of lactate signals, being remarkable in surgical lesions, could be consistent with a common consequence of neurosurgical necrosis. Thus, IH MRS could be a useful modality to evaluate the diagnostic and prognostic implications fur Parkinsons disease after functional neurosurgery.

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Information Hiding Technique in Smart Phone for the Implementation of GIS Web-Map Service (GIS 웹 맵 서비스 구현을 위한 스마트 폰에서의 정보은닉 기법)

  • Kim, Jin-Ho;Seo, Yong-Su;Kwon, Ki-Ryong
    • Journal of Korea Multimedia Society
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    • v.13 no.5
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    • pp.710-721
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    • 2010
  • Recently, for the advancement of embedded technology about mobile device, a new kind of service, mash-up is appeared. It is service or application combining multimedia content making tool or device and web-GIS(geographic information system) service in the mobile environment. This service can be ease to use for casual user and can apply in various ways. So, It is served in web 2.0 environment actively. But, in the mashup service, because generated multimedia contents linked with web map are new type of multimedia contents which include user's migration routes in the space such as GPS coordinates. Thus, there are no protection ways for intellectual property created by GIS web-map service users and user's privacy. In this paper, we proposed a location and user information hiding scheme for GIS web-map service. This scheme embeds location and user information into a picture that is taken by camera module on the mobile phone. It is not only protecting way for user's privacy but is also tracing way against illegal photographer who is peeping person through hidden camera. And than, we also realized proposed scheme on the mobile smart phone. For minimizing margin of error about location coordinate value against contents manipulating attacks, GPS information is embedded into chrominance signal of contents considering weight of each digit about binary type of GPS coordinate value. And for tracing illegal photographer, user information such as serial number of mobile phone, phone number and photographing date is embedded into frequency spectrum of contents luminance signal. In the experimental results, we confirmed that the error of extracted information against various image processing attacks is within reliable tolerance. And after file format translation attack, we extracted embedded information from the attacked contents without no damage. Using similarity between extracted one and original templete, we also extracted whole information from damaged chrominance signal of contents by various image processing attacks.

A Study on the Development of SSB Modem (디지털 SSB 모뎀 개발에 관한 연구)

  • Jin, Heung-Du;Choi, Jo-Cheon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2007.10a
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    • pp.693-697
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    • 2007
  • The SSB modem performs the modulation process which converts the digital voltage level to the audible frequency band signal and the demodulation process which converts reversely the audible frequency signal to the digital voltage level. The modulator and the demodulator are implemented with a single DSP chip. Because of the SSB specific character, the distortion occurs when the frequency is changed. This distortion has no effect on voice communication, but it has an significant effect on data communication. In other words, it is impossible to send data stream with adjacent 2 periods. Therefore, in case of using 2-tone FSK, it is needed to send at least 3 periods to transmit 1 bit. Therefore we implemented the modem using modified phase-delay shift keying to transmit 1 tone signal for high speed transmission. In the 1200[bps] mode, it generates 0, $187{\mu}s$ delay time at 1.3kHz symbol frequency, and in the 2400[bps] mode, 0, $70{\mu}s$, $130{\mu}s$, $200{\mu}s$ delay time at 1.5kHz symbol frequency. Finally, in the maximum 3600[bps] mode, it generates 0, $100{\mu}s$, $160{\mu}s$, $250{\mu}s$ delay time at 2.0kHz symbol frequency. The measured results of the implemented SSB modem shows a good transfer functional characteristic by spectrum analyzer, almost same bandwidth in pass band and 20dB higher SNR comparing the German PACTOR and American CLOVER and in the experimental transmitting test, we verified the transmitted data is received correctly in platform.

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The Study of Optical Biopsy‘s Usefulness in Radiotherapy (방사선 치료에서 광학적 생검의 유용성에 관한 연구)

  • ;;Muller M.G.,;Feld M.S.
    • Progress in Medical Physics
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    • v.12 no.1
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    • pp.9-17
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    • 2001
  • The prior purpose of this study is to introduce a optical biopsy and evaluate whether the optical biopsy, real-time, non-invasive technique, is a reliable tool to assess response to radiotherapy Four healthy volunteers, and four patients with inflammatory conditions of the oral cavity participated on the study. was obtained from each person enrolled in the study. Using FastEEM(Ercited Emission Matrix) as a optical biopsy tool, normal and tumor spectra are taken from the normal and the tumor regions. And then second optical biopsy are taken from the tumor regions in 4 patients with time delay at 7days.. Using a diagnostic algorithm, made by Gillenwater based on spectra excited at 337nm The Optical Biopsy turned out to be more suited for tumor diagnostic resulting in significant difference fluorescence spectra. The fluorescence intensity of cancerous tissue showed a higher position. The second fluorescence intensity of optical biopsy of cancerous oral tissue has more smaller than the first result. I conclude that optical biopsy, which technique don't need to remove tissue sample from body, and is a real time , and non-invasive measurement is a reliable tool to access to radiotherapy because FastEEM can do measure the variation of the tissue composition chemical, biological, and morphological after radiotherapy. Based on the fluorescence spectrum are taken from the optical biopsy in normal and tumor spectra as well as tumor spectra after 7days.

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Characteristics of InGaAs/GaAs/AlGaAs Double Barrier Quantum Well Infrared Photodetectors

  • Park, Min-Su;Kim, Ho-Seong;Yang, Hyeon-Deok;Song, Jin-Dong;Kim, Sang-Hyeok;Yun, Ye-Seul;Choe, Won-Jun
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.324-325
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    • 2014
  • Quantum wells infrared photodetectors (QWIPs) have been used to detect infrared radiations through the principle based on the localized stated in quantum wells (QWs) [1]. The mature III-V compound semiconductor technology used to fabricate these devices results in much lower costs, larger array sizes, higher pixel operability, and better uniformity than those achievable with competing technologies such as HgCdTe. Especially, GaAs/AlGaAs QWIPs have been extensively used for large focal plane arrays (FPAs) of infrared imaging system. However, the research efforts for increasing sensitivity and operating temperature of the QWIPs still have pursued. The modification of heterostructures [2] and the various fabrications for preventing polarization selection rule [3] were suggested. In order to enhance optical performances of the QWIPs, double barrier quantum well (DBQW) structures will be introduced as the absorption layers for the suggested QWIPs. The DBWQ structure is an adequate solution for photodetectors working in the mid-wavelength infrared (MWIR) region and broadens the responsivity spectrum [4]. In this study, InGaAs/GaAs/AlGaAs double barrier quantum well infrared photodetectors (DB-QWIPs) are successfully fabricated and characterized. The heterostructures of the InGaAs/GaAs/AlGaAs DB-QWIPs are grown by molecular beam epitaxy (MBE) system. Photoluminescence (PL) spectroscopy is used to examine the heterostructures of the InGaAs/GaAs/AlGaAs DB-QWIP. The mesa-type DB-QWIPs (Area : $2mm{\times}2mm$) are fabricated by conventional optical lithography and wet etching process and Ni/Ge/Au ohmic contacts were evaporated onto the top and bottom layers. The dark current are measured at different temperatures and the temperature and applied bias dependence of the intersubband photocurrents are studied by using Fourier transform infrared spectrometer (FTIR) system equipped with cryostat. The photovoltaic behavior of the DB-QWIPs can be observed up to 120 K due to the generated built-in electric field caused from the asymmetric heterostructures of the DB-QWIPs. The fabricated DB-QWIPs exhibit spectral photoresponses at wavelengths range from 3 to $7{\mu}m$. Grating structure formed on the window surface of the DB-QWIP will induce the enhancement of optical responses.

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The Synthesis and Properties of Nonlinear Optical Polyquinonediimine Containing Mono-Azobenzene Group in the Side Chain (곁사슬에 모노-아조벤젠기를 갖는 비선형 광학 폴리퀴논디이민의 합성과 성질에 관한 연구)

  • 이상배;양정성;박동규
    • Polymer(Korea)
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    • v.24 no.6
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    • pp.737-743
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    • 2000
  • Polyquinonediimines (PQDI) which have stable structure on heat and contains mono-azobenzene in the side chain were synthesized by means of condensation polymerization under TiCl$_4$. The synthesized monomers and polymers were identified by FT-IR, $^1$H-NMR, and elementary analysis. Especially, PQDI was comfirmed by the double-bonding peak of >C=N appeared near 1625 $cm^{-1}$ / by means of FT-IR spectrum. PQDI containing mono-azobenzene group in both side chains wat not soluble in non-polar solvents at all but partially soluble in the polar solvents having small dielectric constant, and dissolved in the strong acid such as sulfuric acid and $CH_3$SO$_3$H. Molecular weight distribution of PQDI measured by GPC showed 1.74. It was confirmed through X-ray diffraction analysis that the polymer was partially crystalline at the low angle region, but amorphous after heat treatment at 1$25^{\circ}C$. The glass transition temperature (T$_{g}$ ) of synthesized polymer was measured as 1$25^{\circ}C$ by differential scanning calorimetry. The SHG value for $\chi$$^{(2)}$ after poling at 1$25^{\circ}C$ was 8.6 pm/V (λ=1.542 ${\mu}{\textrm}{m}$). The SHG value slowly decreased with time from the start but appeared temporal stability after 100 hours.

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Properties of Yttria Partially Stabilized Zirconia Nano-Powders Prepared by Coprecipitation Method (공침법으로 합성한 이트리아 부분안정화 지르코니아 나노분말의 특성)

  • Yoon, Hye-On;Shin, Mi-Young;Ahn, Joong-Jae
    • Journal of the Mineralogical Society of Korea
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    • v.19 no.2 s.48
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    • pp.81-88
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    • 2006
  • The Yttria Partially Stabilized Zirconia powder was prepared by spontaneous precipitation method using $ZrOCl_2{\cdot}8H_O-YCl_33{\cdot}6H_2O$ solution as a starting materials. The optimal experimental conditions such as concentration and pH of starting solutions, the amounts of stabilizer $Y_2O_3$ used, and sintered temperature were carefully studied. The best condition for synthesizing $ZrO_2$ was experimentally selected and applied throughout this study for the preparation of the 3 mole% $Y_2O_3$ partially stabilized zirconia, 3YSZ. The physical properties of 3YSZ was examined by XRD, Raman, DT A, and SEM. The structural transition from pure monoclinic high temperature $ZrO_2$ to tetragonal room temperature 3YSZ was made possible by the added amount of $Y_2O_3$ in the $ZrO_2+Y_2O_3$ system. All Raman Spectrum band appeared in the lower wave numbers rather than in higher wave numbers as structure changes from monoclinic to tetragonal.

Spectral Characteristics of Heavy Metal Contaminated Soils in the Vicinity of Boksu Mine (복수광산 주변 중금속 오염 토양의 분광학적 특성)

  • Shin, Ji Hye;Yu, Jaehyung;Jeong, Yong Sik;Kim, Seyoung;Koh, Sang-Mo;Park, Gyesoon
    • Journal of the Mineralogical Society of Korea
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    • v.29 no.3
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    • pp.89-101
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    • 2016
  • This study investigated spectral characteristics of heavy metal contaminated soil samples in the vicinity of abandoned Boksu mine. Heavy metal concentrations including arsenic, lead, zinc, copper and cadmium were analyzed by XRF analysis. As a result, all of the soil samples excluding control sample were over-contaminated based on the counter measure standard. The XRD results revealed that quartz, kaolinite and smectite were detected for all of the soil samples and heavy metals in soil were adsorbed on clay minerals such as kaolinite and smectite. The spectral analyses confirmed that spectral reflectance of near-infrared and shorter portion of shortwave-infrared spectrum decreases as heavy metal concentration increases. Moreover, absorption depths at 2312 nm and 2380 nm, the absorption features of clay minerals, decreases with higher heavy metal concentration indicating adsorption of heavy metal ions with clay minerals. It indicates that spectral features and heavy metal contamination of soil samples have high correlations.

A Molecular Dynamics Simulation Study of Hydroxyls in Dioctahedral Phyllosilicates (분자동역학 시뮬레이션을 이용한 이팔면체 점토광물 수산기 연구)

  • Son, Sangbo;Kwon, Kideok D.
    • Journal of the Mineralogical Society of Korea
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    • v.29 no.4
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    • pp.209-220
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    • 2016
  • Clay minerals are a major player to determine geochemical cycles of trace metals and carbon in the critical zone which covers the atmosphere down to groundwater aquifers. Molecular dynamics (MD) simulations can examine the Earth materials at an atomic level and, therefore, provide detailed fundamental-level insights related to physicochemical properties of clay minerals. In the current study, we have applied classical MD simulations with clayFF force field to dioctahedral clay minerals (i.e., gibbsite, kaolinite, and pyrophyllite) to analyze and compare structural parameters (lattice parameter, atomic pair distance) with experiments. We further calculated vibrational power spectra for the hydroxyls of the minerals by using the MD simulations results. The MD simulations predicted lattice parameters and interatomic distances respectively deviated less than 0.1~3.7% and 5% from the experimental results. The stretching vibrational wavenumber of the hydroxyl groups were calculated $200-300cm^{-1}$ higher than experiment. However, the trends in the frequencies among different surface hydroxyl groups of each mineral was consistent with experimental results. The angle formed by the surface hydroxyl group with the (001) plane and hydrogen bond distances of the surface hydroxyls were consistent with experimental result trends. The inner hydroxyls, however, showed results somewhat deviated from reported data in the literature. These results indicate that molecular dynamics simulations with clayFF can be a useful method in elucidating the roles of surface hydroxyl groups in the adsorption of metal ions to clay minerals.

A Study on TDMG Pulse Performance and Structure for Performance Improvement of UWB system (UWB 시스템의 성능개선을 위한 TDMG 펄스 발생기의 성능과 구조에 관한 연구)

  • Ko, Young-Eun;Bang, Sung-Il
    • The KIPS Transactions:PartC
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    • v.11C no.3
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    • pp.395-400
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    • 2004
  • Being aware of growing needs for wireless communication led to the development of UWB systems, this study proposed an impulse for single band UWB systems which does not count a carrier; analyzed the characteristics and the problems of pulses suggested by the existing poise of the Un system; finally, proposed TDMG(Time Delay Multiple Gaussian) pulse that generates signals of UWB without attenuation of pulse width. The hardware structure of the TDMC pulse for the single band UWB system was modelled after describing the pulse in a mathematical method in an attempt to compare with performances of the existing pulses through computer simulation. The outcome of the test unveiled the fact that each center frequency of the TDMG pulse rose approximately 1GHz, and also each l0dB fractional bandwidth of the TDMG pulse was widened over 1GHz. In the case of derivative, center frequencies of the TDMG pulse rose over 1GHz each. As a consequence, the TDMG pulse appeared to have better quality frequency, satisfying the characteristics of spectrum and the band of frequency recommended by the FCC and decreasing interference with other wireless communication systems.