• Herbal Formula Science
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• v.28 no.1
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• pp.29-39
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• 2020

Objectives : Glucoraphanin is one of the well-known natural glucosinolates found in cruciferous plants. In the present study, we investigated the effects and molecular mechanism of glucoraphanin in dexamethasone-induced skeletal muscle atrophy in vitro model. Methods : The cytotoxic effects of glucoraphanin on C2C12 myoblasts or myotubes were evaluated by MTT assay. The glucoraphanin was evaluated effects in dexamethasone-induced skeletal muscle atrophy in C2C12 myotubes using a real-time PCR, western blots analysis, and immunofluorescence staining of myosin heavy chain. Result : Glucoraphanin had no cytotoxicity on both C2C12 myoblasts or myotubes. Dexamethasone markedly induced muscle atrophy by up-regulating muscle-specific ubiquitin E3 ligase markers, atrogin-1 and MuRF1, and down-regulating MyoD, a myogenic regulatory factor whereas co-treatment of glucoraphanin and dexamethasone dose-dependently inhibited it. Furthermore, decreased expressions of p-Akt, p-FOXO1, and p-FOXO3a induced by dexamethasone were reversed by co-treatment with glucoraphanin and dexamethasone. In addition, dexamethasone obviously reduced myotube diameters, while co-treatment of glucoraphanin and dexamethasone increased those to a similar level as control. Conclusions : These results show that glucoraphanin suppresses dexamethasone-induced muscle atrophy in C2C12 myotubes through activation of Akt/FOXO signaling pathway.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.27 no.3
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• pp.209-213
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• 2001

Treatment of oral cancers with chemotherapeutic agents are evaluated as an effective method for remission to reduce cancer proliferation nowadays. But, minimization of side-effects such as bone marrow suppression, gastrointestinal toxicity and renal damage is another problem to be solved. Thus, a possible approach to develop a clinically applicable chemotherapeutic agents is to screen anticancer activity among traditional medicinal plants which have been used for thousands of years with very low side-effects in orient. In this study we focused on anti-oral cancer activities of momordin, which was medicinal plant extracts that was revealed anticancer activities, on KB cell(oral cancer cell). The results were as follow : 1. Momordin showed the excellent anti-oral cancer activity against KB cells. Obtained IC50 value of Momordin was $10.4{\mu}g/ml$. 2. When KB cells were treated with Momordin, dose and time dependent DNA fragmentation of KB cells were observed. DNA fragmentation was initiated on three days at the concentration of $20{\mu}g/ml$ Momordin. 3. Flow cytometry showed dose-dependent apoptotic cell increase of KB cells on Momordin. 18.55% apoptotic cell were observed up to 72 hours at the concentration of $20{\mu}g/ml$ of Momordin. 4. Momordin induced nonspecific apoptosis without specific cell cycle arrest. 5. Through MTT assay, DNA fragmentation assay and flow cytometric analysis. anticancer effect of Momordin against KB cell was induce of apoptotic cell death.

• Journal of Korean Society of Forest Science
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• v.82 no.4
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• pp.396-405
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• 1993

In this paper, a nonlinear programming model to determine the optimal operating policy to minimize production costs for particleboard plants is presented. The model provides optimal values for three decision variables : specific gravity of particleboard, mat moisture content and mat resin content. These decision variables are key factors influencing the cost and quality of particleboard manufacturing processes. In formulating the nonlinear programming model, the minimum quality standards for internal bond strength and modulus of rupture of particleboard are used as industry-wide quality constraints. These quality standards are expressed as nonlinear functions of the decision variables. In order to demonstrate the applicability of the proposed model, the model is applied to solve for optimal solutions of four theoretical problems. The problem scenarios are built to investigate effects of changes in hot-pressing speed and purchase price of chip and resin.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2007.10a
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• pp.437-440
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• 2007

Recently embedded system developed a lot. Physically, embedded systems range from portable devices such as digital watches and MP3 players, to large stationary installations like traffic lights, factory controllers, or the systems controlling nuclear power plants. This paper focuses on implementation of portable device which is applicable to the child-kidnap or missing child prevention system in residential area or public area. To be specific, this device is to transmit video data which comes from the camera in the device into the host PC via WLAN. Embedded hardware platform consists of s3c2440 with ARM9 core, WindowsCE OS and other sensors. OS enables the platform to do multitasking jobs which are handling GPS data, taking video, capturing audio via microphone in the device and transfer all kind of realtime data to the host PC.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.5 no.3
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• pp.227-231
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• 2004

It is the common features of the integral reactors that the main components of the RCS are installed within the reactor vessel, and so there are no any flow pipes connecting the steam generator or the pump whose type is the axial flow. Due to no any flow pipes, it is impossible to measure the differential pressure at the RCS of the integral reactors, and it also makes impossible measure the flow-rate of the reactor coolant. As a alternative method, the method by the measurement of the pump power of the axial flow pump has been introduced in this study. Up to now, we did not found out a precedent which the pump power is used for the flow-rate calculation at normal operation of the commercial nuclear power plants. The objective of the study is to embody the flow-rate calculation method by the measurement of the pump power in an integral reactor. As a result of the study, we could theoretically reason that the capacity-head curve and capacity-shaft power curve around the rated capacity with the high specific-speeded axial flow pumps have each diagonally steep incline but show the similar shape. Also, we could confirm the above theoretical reasoning from the measured result of the pump motor inputs. So, it has been concluded that it is possible to calculate the flow-rate by the measurement of the pump motor inputs.

• Journal of Microbiology and Biotechnology
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• v.14 no.4
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• pp.885-890
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• 2004

A survey for vesicular-arbuscular mycorrhizae (VAM) occurrence was undertaken in three endangered vegetation sites in the area of Kudankulam atomic power station. Fifteen VAM fungal species were isolated from the root-zone soils of fourteen different plant species. There was a significant correlation observed between the number of spores and of percentage root colonization as exemplified by Phyllanthus niruri and Paspalum vaginatum (450, 95%; 60, 25%). Although VAM species are not known to be strictly site specific, the fact that Acaulospora elegans was observed only in site 1, Glomus pulvinatum in site 2 only, and Gl. intraradices in site 3 only, showed site-specificity in this study. To confirm the infection efficiency, two host plant species in the sites, P. niruri and Eclipta alba, were selected and inoculated in field with three selected VAM fungal spores. Gl. fasciculatum was found to be the most efficient VAM species in percentage root colonization, number of VAM spores, and dry matter content. When the nutrients in roots of P. niruri and E. alba were analyzed, there was higher uptake of K (4.2 and 3.4 times, respectively) and Ca (5.3 and 4.9 times, respectively), the analogues for $^{137}Cs$ and $^{90}Sr$, respectively. From the results, it might be concluded that VAM association helps the plants survive in a disturbed ecosystem and enhances uptake and cycling of radionuclides from the ecosystem.

• Journal of Environmental Science International
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• v.28 no.12
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• pp.1147-1156
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• 2019

The purpose of this study was to analyze examples of green infrastructure presented by the American Society of Landscape Architects as a part of basic research to assess hub green spaces in cities. With the specific goal of green infrasturcture in mind, the study samples were classified according to their purpose: 'humanities', 'hydrology', 'ecology', and 'environment'. Based on this we assessed the elements of planning for the target sites and obtained the following results. With regard to the aspect of humanities, planning urban hub green spaces was related to the satisfaction in leisure activities and the 'quality of life' that people expect to enjoy at parks or other green areas in general. Rather than focusing on direct and visible benefits, which might come from green infrastructure's technological elements, people hoped that parks and green areas have macroscopic values. For hydrological characteristics, the 'ecologically manages stormwater' was applied the most in planning hub green spaces in cities, and it mainly took the form of technological elements or factors. Third, the planning elements pertaining to ecological characteristics were identified as a combination of strategies and technological elements that 'reintroduces native plants' and 'habitat for wildlife'. As for the plans to instill eco-friendly aspects, the study found that the research on air, climate, weather, heat reaction, soil, energy efficiency, and use and application of resources is important. However, it was difficult to measure the potential quantitative benefits of 'reusing or recycling materials', 'reducing urban heat', and 'cooling air temperature'. The result of this study is meaningful in that it can be used for the assessment of urban hub green spaces in the future.

• Journal of the Korean Society of Fashion and Beauty
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• v.5 no.3
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• pp.111-117
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• 2007

Essential oils aims to rejuvenate and beautify medical skin care the body through the use of essential oils, and generally to improve our outward appearance. Much of this section fouses on the different methods by which essential oils can be used to improve the complexion or to treat specific medical care skin conditions. Beauty, however, is not just skin-deep. The condition of the medical care express the overall health of an individual. A relaxed attitude, together with a well-balanced diet, enough exercise, and a daily intake of plenty of spring water or herbal teas, all help to keep the system in top condition. Essential oils is a healing art which has powerful effects on both mind and body. The vital element in essential oils is the pure oils which are extracted from various part of different plants. The key to medical aromatherapy care lies in its dual use of essential oils and medical care massage, thus masking full use of two of our most important senses-smell and touch. Medical aromatherapy care is holistic, working mainly on the nervous system and including the head and body as part of the same treatment. Using pressure points along the spine, Medical aromatherapy care on the autonomic nervous system and has an immediate effect of relexation. In directly it also acts on mood. Many of the medical massage movements help lymphatic drainage. Essential oils have many different qualities; they can be relaxing or invigorating and are generally antisepic and antibacterial. Medical aromatherapy care can have psychological benefits. The power of essences in healing has been recognized in the treatment of insect bites. Clove, thyme, sandalwood, and lavender are a few of the essences that have antiseptic. Essential oils effect the dry skin for small visual pores, dull matte finish, rough sandy feeling, tantskin. Essential oils effect the mature/sun damaged skin for some red or couperose areas, loose saggy skin, exposure to a lot of ultraviolet light. Essential oils effect the medical care nomal skin good elasticity, healthy color(good circulation), smooth terture.

• Tunnel and Underground Space
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• v.22 no.6
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• pp.449-461
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• 2012

Coal ash generated from thermal power plants is planned to use for mine filling in order to prevent subsidence of the ground. In according, the basic physical properties and flow characteristics were grasped using coal ash from generated Yeongdong thermal power plant, and hydraulic filling experiments were performed a total of eight times by manufacturing the model of 1 inclined shaft in Hanbo coal mine. The specific gravity of coal ash is 2.34, and the result of particle size analysis belongs to silty sand (SM). Coal ash of weight ratio of 60% was used in the filling experiments of the model, since liquefaction have shown in coal ash less than weight ratio of 70% from the result of slump and flow test. The outlet should be located at the bottom of the inclined and vertical shaft, this was favorable way in improving the filling efficiency from the experiment results regardless of groundwater exists.

• Journal of Environmental Impact Assessment
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• v.22 no.5
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• pp.409-426
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• 2013

The purpose of this study is to present the raw data for management and conservation of tidal flat by objective surveying and analysing the halophytes and vegetation distributed in Seocheon tidal flat wetland conservation area, Korea. The results are as follows. The numbers of halophytes in this site were summarized as 27 taxa including 13 families, 21 genera, 26 species and 1 variety. In the results of ecologically important species, rare plant was 1 taxa, 10 taxa of the specific plants by floristic region, 1 taxa of naturalized plant and 1 taxa of the plant with approval for delivering oversea. The life form spectrum consisted of therophytes(44.4%), hemicryptophytes(25.9%), geophytes(14.8%), nanophanerophytes(7.5%), chamaephytes and hydatophytes(each 3.7%). The types of vegetation of Seocheon tidal flat wetland conservation area were classified with 17 communities including Vitex rotundifolia community, Suaeda maritima community, Calystegia soldanella community and so forth. In the halophytes composition, section C and E-1 had the largest character species and companion species. In the results of vegetation amount, section C, D, E-1 and E-2 were the highest score, on the other hand, section A and B were the lowest. The final rating was calculated by adding up values of two factors, and section C and E-1 had the highest rating of II. In future, we will survey the whole flora in Seocheon tidal flat, we will offer the help to establishing the conservation plan of coastal plant ecosystem in West Sea.