• Journal of the Korean Association of Geographic Information Studies
• /
• v.21 no.4
• /
• pp.14-25
• /
• 2018

The operation of high-speed rail (HSR) has an effect on the agglomeration economies, and the impact is shown as a relocation of individual firm and worker to where business activity can be maximized. The proximity to the HSR station could be considered as a core district to maximize the industrial benefit through the HSR network. From this perspective, this study considers the agglomeration effect of HSR within the HSR station-area and analyzed the agglomerated spatial pattern through hotspot analysis by service industry in the cases of Korea and Japan using GIS. This study analyzed the service industry within 1km distance from 8 HSR stations of Korea and 4 Kyushu Shinkansen stations of Japan. The results suggest that the hotspot patterns are observed in the service industry within 1km distance from the HSR station of Korea and Japan, except for two HSR stations of Gupo station and Kagoshima-Chuo station. Leisure, amusement, association, and other specific service industries could be affected by HSR passengers and knowledge-spillovers through HSR station. Therefore, the observed hotspot districts near the HSR station-area could explain an agglomeration pattern of the service industry through a closeness to the HSR station. Further, we could expect that the impact of HSR affects the service industry, and the impact could attract business activities of the service-area to maximize their benefit from HSR travelers. With the result, it is required to build up a supportive policy to maximize the HSR's impact on the service industry when considering the HSR station-area development.

• Journal of Life Science
• /
• v.29 no.8
• /
• pp.888-894
• /
• 2019

Cartilage diseases, such as rheumatoid arthritis (RA) and osteoarthritis (OA), are associated with the loss of chondrocytes and degradation of articular cartilage. Recent studies revealed that inflammatory reactive oxygen species (ROS) and age-related oxidative stress can affect chondrocyte activity and cartilage homeostasis. We investigated changes in the levels of intracellular antioxidants during cellular senescence of primary chondrocytes from rat articular cartilages. Cellular senescence was induced by serial subculture (passages 0, 2, 4, and 8) of chondrocytes and measured using specific senescence-associated ${\beta}$-galactosidase ($SA-{\beta}-gal$) staining. ROS production increased significantly in the senescent chondrocytes. In addition, total glutathione (GSSG/GSH) and superoxide dismutase (SOD) levels and heme oxygenase-1 (HO-1) expression increased in senescent chondrocytes induced by serial subculture. Analysis of changes in intracellular antioxidant levels in articular cartilage from rats of different ages (5, 25, 40, and 72 wk) revealed that total glutathione levels were highest after 40 wk and slightly decreased after 72 wk as compared with those after 25 wk. SOD and HO-1 expression levels increased in accordance with age. Based on these results, we conclude that intracellular antioxidants may be associated with cartilage protection against excessive oxidative stress in the process of chondrocyte senescence and age-related cartilage degeneration in an animal model.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
• /
• v.14 no.3
• /
• pp.13-26
• /
• 2019

There is a growing interest in the entrepreneurial activity that has long been considered essential for sustainable economic development and value creating. Although it is strongly encouraged by focusing on the positive aspects of venturing, less has been paid attention to entrepreneurial failure, which is the biggest cause of hesitation in starting a business. The uncertain and risky nature of entrepreneurship implies a considerable possibility of failure. Even if it fails, the experience and knowledge of entrepreneurs acquired through entrepreneurship indeed offers valuable lessons for the re-venturing, which can serve as an important social asset that should not be lost. It has been argued that re-entering the same industry for the subsequent venture maximizes the learning effect through utilizing potential benefits from industry-specific knowledge. Although the re-startup after entrepreneurial failure is a very important topic in the studies on serial entrepreneurs, there is a paucity of systematic empirical investigation. This study responds to calls for more research on the re-startup after entrepreneurial failure, and specifically complements existing studies on serial entrepreneurs. Focusing on the entrepreneurs' attribution for the failure, we conducted an empirical analysis of how this affects the re-startup process. Moreover, we also examined the moderating effects of entrepreneurial self-efficacy and resilience. For the analyses, we surveyed the entrepreneurs who tried to re-start the subsequent business after the entrepreneurial failure through the "Revitalization Center for Strained Entrepreneur". The results found that failed entrepreneurs who blamed internal factors for their previous venture failures were likely to keep the same industry for their subsequent business. In addition, the positive effect of internal attribution on maintaining the same industry for the re-startup was found to be stronger when entrepreneurial self-efficacy and resilience were high.

• Journal of Life Science
• /
• v.29 no.5
• /
• pp.614-620
• /
• 2019

The purpose of this study was to examine the growth plate, femoral bone length, bone mineral density, and blood composition in various experimental animals fed with oriental medicinal herbs containing growth factors. First, the lengths of the bone growth plates of the positive control (PC) group (fed with Astragalus membranaceus) and the Gh-199 and Sh-188 groups were increased when compared to group N. The Gh-199 group showed a greater increase in bone growth when compared with the PC group. In terms of the femoral bone length and bone mineral density, the effect of both Gh-199 and Sh-188 powders were as good as those of the PC group, and the Gh-199 powder showed a positive effect. Conversely, in the PC group, unlike the Gh-199 and Sh-188 groups, the aspartate aminotransferase(AST) and alanine aminotransferase(ALT) activities in the blood were increased, indicating that A. membranaceus is toxic to the body. Both the PC and Sh-188 groups also showed higher insulin-like growth factor-1(IGF-1) activity when compared with the Gh-199 group. Overall, the bone growth plate, femoral bone length, and bone mineral density measurements, and the blood analysis showed positive results in the group treated with Gh-199, and no specific toxicity of the herbal medicine in the body was evident.

• Food Engineering Progress
• /
• v.21 no.2
• /
• pp.116-125
• /
• 2017

This study aims to make extruded rice snack with high quality in texture and nutrition by adding mealworm. Addition of the mealworm has the merit to fill in high-quality protein and unsaturated fatty acids which are insufficient in rice. Thus, the physicochemical properties were investigated through the process of extrusion cooking. As the extrusion process varied, the die temperatures were set to $120^{\circ}C$ and $130^{\circ}C$. Also, the moisture contents were adjusted to 30% and 35%. The specific length, the expansion ratio, and the water absorption index increased as the added content of mealworm became higher. On the contrary, the density, the breaking strength, the apparent elastic modulus, and the water solubility index decreased. As mealworm and moisture content increased, DPPH radical scavenging activity significantly increased but the rancidity decreased. As a result, the addition of mealworm to the extruded rice snack was effective in improving texture, nutrition, and antioxidation.

• Journal of Radiation Protection and Research
• /
• v.45 no.4
• /
• pp.178-186
• /
• 2020

Background: Reactor pressure vessel (RV) with internals (RVI) are activated structures by neutron irradiation and volume contaminated wastes. Thus, to develop safe and optimized disposal plan for them at a disposal site, it is important to perform exact activation calculation and evaluate the dose rate on the surface of casks which contain cut-off pieces. Materials and Methods: RV and RVI are subjected to neutron activation calculation via Monte Carlo methodology with MCNP6 and ORIGEN-S program-neutron flux, isotopic specific activity, and gamma spectrum calculation on each component of RV and RVI, and dose rate evaluation with MCNP6. Results and Discussion: Through neutron activation analysis, dose rate is evaluated for the casks containing cut-off pieces produced from decommissioned RV and RVI. For RV cut-off ones, the highest value of dose rate on the surface of cask is 6.97 × 10-1 mSv/hr and 2 m from it is 3.03 × 10-2 mSv/hr. For RVI cut-off ones, on the surface of it is 0.166 × 10-1 mSv/hr and 2 m from it is 1.04 × 10-1 mSv/hr. Dose rates for various RV and RVI cut-off pieces distributed lower than the limit except the one of 2 m from the cask surface of RVI. It needs to adjust contents in cask which carries highly radioactive components in order to decrease thickness of cask. Conclusion: Two types of casks are considered in this paper: box type for very-low-level waste (VLLW) as well as low-level waste (LLW) and cylinder type for intermediate-level waste (ILW). The results will contribute to the development of optimal loading plans for RV and RVI cut-off pieces during the decommissioning of nuclear power plant that can be used to prepare radioactive waste disposal plans for the different types of wastes-ILW, LLW, and VLLW.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.22 no.3
• /
• pp.697-706
• /
• 2021

The purpose of this study is to find out whether the many start-up support programs provided by a college can actually help students start a business, and to discuss what role colleges should have as facilitators of student entrepreneurship. To this end, a qualitative study was conducted with seven students who wished to start a business by utilizing start-up education and support programs provided by College Y. As a result of the study, the participants first mentioned parallel and administrative inefficiency in entrepreneurship and the entrepreneurship programs. Second, the implications for the role of colleges in fostering start-up content are systematic planning and guidance for start-up programs operated by the college, concise administrative procedures, mentoring in various start-up items, and securing a test market. It can be said that the concept of a common office in which students can work together is necessary. The study is significant in that it can help to establish a start-up support plan by suggesting what role colleges should play in relation to entrepreneurship, but its limitation is that its scope includes only one specific major.

• Applied Chemistry for Engineering
• /
• v.22 no.2
• /
• pp.167-172
• /
• 2011

In this work, the effect of surface treatment on mesoporous carbons (MCs) supports was investigated by analyzing surface functional groups. MCs were prepared by a conventional templating method using mesoporous silica (SBA-15) for using catalyst supports in direct methanol fuel cells (DMFCs). The MCs were treated with different phosphoric acid ($H_3PO_4$) concentrations i.e., 0, 1, 3, 4, and 5 M at 343 K for 6 h. And then Pt-Ru was deposited onto surface treated MCs (H-MCs) by chemical reduction method. The characteristics of Pt-Ru catalysts deposited onto H-MCs were determined by specific surface area and pore size analyzer, X-ray diffraction, X-ray photoelectron, transmission electron microscopy, and inductive coupled plasma-mass spectrometer. The electrochemical properties of Pt-Ru/H-MCs catalysts were also analyzed by cyclic voltammetry experiments. From the results of surface analysis, an oxygen functional group was introduced to the surface of carbon supports. From the results, the H4M-MCs carbon supports surface treated with 4 M $H_3PO_4$ led to uniform dispersion of Pt-Ru onto H4M-MCs, resulting in enhancing the electro-catalytic activity of Pt-Ru catalysts.

• Journal of the Korea Institute of Information Security & Cryptology
• /
• v.13 no.6
• /
• pp.17-32
• /
• 2003

The information drive of the businesses requires new alternatives in that the promotion of business efficiency through information process technologies ends up conflicting with the protection of information human rights on laborers' side. Nevertheless, apathy on information protection has a tendency to be distorted by the efficiency of the businesses. Should the capital and mass media warn economic red lights, political circles with uneasiness would ignore the significance of information protection on the behalf of business efficiency. Therefore, the importance of information protection is considered a smaller interest than that of business efficiency with the infringements of human rights on laborers' side arising. Informatization of the businesses along with the developments of information process technologies has enabled the management to monitor and control the behaviors of laborers. This new problem needs to establish both information protection mechanism and institutional devices to regulate those labor controls. The security of business activity without human rights infringement warrants both basic rights of the public and spirit of the Constitution. The study suggests the establishment and revision of laws suitable to the period of information human rights. On top of that, the establishment of the basic law for information protection of individuals' with the common principle that integrates the related laws and rules on-off line is needed. This will warrant the active participation of labor unions and create specific alternatives for information protection.

• Applied Chemistry for Engineering
• /
• v.32 no.3
• /
• pp.326-331
• /
• 2021

In this study, the preparation conditions for a TiO₂-based vanadium-based catalyst for oxidizing hydrogen sulfide at room temperature were optimized. Four types of commercial TiO₂ were used as a catalyst support and the performance evaluation of hydrogen sulfide oxidation at room temperature of V/TiO₂ by varying vanadium contents prepared using the impregnation method was performed. Among the types of TiO₂ tested, it was confirmed that the catalyst with the vanadium content of 5% and based on TiO₂(A) has the best hydrogen sulfide conversion rate of 58%. By comparing the physical and chemical properties of the catalyst, the specific surface area of the support and the species of dominant vanadium are the major factor in catalyst performance. In order to confirm the regeneration characteristics of the catalyst with reduced activity, heat treatment was performed at 400 ℃ for 2 h, and the amount of hydrogen sulfide oxidation decreased by 10% due to the partial deposition of sulfur in the regenerated catalyst, but it was confirmed that the initial performance was similar.