• Korean Journal of Ecology and Environment
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• v.50 no.2
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• pp.216-237
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• 2017

Thermal effluent of the hot spring has long been a field of interest in the relationship between temperature gradient and freshwater algae in geology, limnology and aquatic ecology throughout the world. On the other hand, many artificial hot springs have been developed in Korea, but the research on them has not been still active. This study was performed every month from December 2015 to September 2016, to elucidate the spatiotemporal effects of thermal wastewater effluent (TWE) on the ecosystem of benthic algal assemblage in four stations(BSU (upstream), HSW (hot spring wastewater outlet), BSD1~2 (downstream)) of the upstream reach of the Buso Stream, a tributary located in the Hantan River basin. During the survey, the influencing distance of temperature on TWE was <1.0 km, and it was the main source of N P nutrients at the same time. The effects of TWE were dominant at low temperature and dry season (December~March), but it was weak at high temperature and wet season (July~September), reflecting some seasonal characteristics. Under these circumstances, the attached algal communities were identified to 59 genera and 143 species. Of these, the major phylum included 21 genera 83 species of diatoms(58.0%), 9 genera 21 species of blue-green algae (14.7%) and 25 genera 32 species of green algae (22.4%), respectively. The spatiotemporal distribution of them was closely related to water temperature ($5^{\circ}C$ and $15^{\circ}C$) and current ($0.2m\;s^{-1}$ and $0.8m\;s^{-1}$). In the basic environment maintaining a high water temperature throughout the year round, the flora favoring high affinity to $PO_4$ in the water body or preferring stream habitat of abundant $NO_3-PO_4$ was dominant. As a result, when compared with the outcomes of previous algal ecology studies conducted in Korea, the Buso Stream was evaluated as a serious polluted state due to persistent excess nutrient supply and high thermal pollution throughout the year round by TWE. It can be regarded as a dynamic ecosystem in which homogeneity (Summer~Autumn) and heterogeneity (Winter~Spring) are repeated between upstream and downstream.

• Korean Journal of Ecology and Environment
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• v.51 no.4
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• pp.268-286
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• 2018

The eutrophication and algal blooms by harmful cyanobacteria (CyanoHAs) and freshwater redtide (FRT) that severely experiencing in typical regulated weir system of the Nakdong River are one of the most rapidly expanding water quality problems in Korea and worldwide. To compare with the factors of rainfall, hydrology, and dominant algae, this study explored spatiotemporal variability of the major water environmental factors by weekly intervals in eight weir pools of the Nakdong River from January 2013 to July 2017. There was a distinct difference in rainfall distribution between upstream and downstream regions. Outflow discharge using small-scale hydropower generation, overflow and fish-ways accounted for 37.4%, 60.1% and 2.5%, respectively. Excluding the flood season, the outflow was mainly due to the hydropower release through year-round. These have been associated with the drawdown of water level, water exchange rate, and the significant impact on change of dominant algae. The mean concentration (maximum value) of chlorophyll-a was $17.6mg\;m^{-3}$ ($98.2mg\;m^{-3}$) in the SAJ~GAJ and $29.6mg\;m^{-3}$ ($193.6mg\;m^{-3}$) in the DAS~HAA weir pools reaches, respectively. It has increased significantly in the downstream part where the influence of treated wastewater effluents (TWEs) is high. Indeed, very high values (>50 or $>100mg\;m^{-3}$) of chlorophyll-a concentration were observed at low flow rates and water levels. Algal assemblages that caused the blooms of CyanoHAs and FRT were the cyanobacteria Microcystis and the diatom Stephanodiscus populations, respectively. In conclusion, appropriate hydrological management practices in terms of each weir pool may need to be developed.

• Journal of the Korean Geographical Society
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• v.47 no.5
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• pp.677-699
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• 2012

Climate changes may cause substantial changes in spatial patterns and distribution of vector-borne diseases (VBD's), which will result in a significant threat to humans and emerge as an important public health problem that the international society needs to solve. As global warming becomes widespread and the Korean peninsula characterizes subtropical climate, the potentials of climate-driven disease outbreaks and spread rapidly increase with changes in land use, population distributions, and ecological environments. Vector-borne diseases are typically infected by insects such as mosquitoes and ticks, and infected hosts and vectors increased dramatically as the habitat ranges of the VBD agents have been expanded for the past 20 years. Medical geography integrates and processes a wide range of public health data and indicators at both local and regional levels, and ultimately helps researchers identify spatiotemporal mechanism of the diseases determining interactions and relationships between spatial and non-spatial data. Spatial epidemiology is a new and emerging area of medical geography integrating geospatial sciences, environmental sciences, and epidemiology to further uncover human health-environment relationships. An introduction of GIS-based disease monitoring system to the public health surveillance system is among the important future research agenda that medical geography can significantly contribute to. Particularly, real-time monitoring methods, early-warning systems, and spatial forecasting of VBD factors will be key research fields to understand the dynamics of VBD's.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.5 no.1 s.9
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• pp.1-12
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• 2006

In order to estimate a dynamic origin and destination demand between on and off-ramps in the freeways, a traffic flow theory can be used to calculate a link distribution proportion of traffics moving between them. We have developed a dynamic traffic estimation model based on the three-phase traffic theory (Kerner, 2004), which explains the complexity of traffic phenomena based on phase transitions among free-flow, synchronized flow and moving jam phases, and on their complex nonlinear spatiotemporal features. The developed model explains and estimates traffic congestion in terms of speed breakdown, phase transition and queue propagation. We have estimated the link, on and off-ramp volumes at every time interval by using traffic data collected from vehicle detection systems in Korea freeway sections. The analyzed results show that the developed model describes traffic flows adequately.

• Development and Reproduction
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• v.4 no.1
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• pp.37-43
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• 2000

Spatiotemporal expression of two isoforms of zonular occludens-1 (ZO-1), tight junctional protein, was examined in mouse testis. By RT-PCR, transcripts encoding two isoforms of ZO-1; ZO-1$\alpha$+ and ZO-1$\alpha$- were detected in testis. Two different forms of ZO-1 antigens with Mr.225 and 2001 KDa were detected in western blot of extract of neonatal to adult testis, coinciding with the result of RT-PCR. The relative amount of ZO-1 $\alpha$- versus 20-1 $\alpha$＋ increased as the mice matured. In immunostaining using the pan antibody which detected both isoforms, ZO-1 was localized in the intercellular spaces in the Sertoli cell - Sertoli cell contacts in periphery of seminiferous tubule as well as Sertoli cell - germ cells contacts within the seminiferous tubule. The expression of ZO-1 was ubiquitous in both junctional area and cytoplasm of seminiferous tubule components. However, more intense signals were found in Sertoli cell junctional areas according to sexual maturation. The changes in the relative amount of both isoforms and spatial distribution of ZO-1 at the periphery of seminiferous tubule might be important for functional appearance of blood testis barrier and spermatogenesis.

• Korean Journal of Agricultural and Forest Meteorology
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• v.7 no.1
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• pp.66-77
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• 2005

We have investigated microclimatic controls on the spatiotemporal variations of net primary production (NPP) of a rugged forested watershed using the process-based biogeochemical model (BIOME-BGC). To validate the model simulation of water and carbon cycles at the plot scale, we have conducted field survey over deciduous broadleaf forest (DBF) and evergreen needleleaf forest (ENF) since 2000. The modeled values of soil temperature, soil moisture and soil respiration showed high correlation with those from the field measurements. The modeled seasonal changes of NPP showed high correlation with air temperature but no significant correlation with water related parameters. The precipitation frequency turned out to be the best climatic factor to explain the annual variation of NPP. Furthermore, NPP of ENF was more sensitive to precipitation frequency than that of DBF. With changes in vegetation cover and topography, the spatial distribution of NPP was of great heterogeneity, which was negatively correlated with the magnitude of NPP. Despite the annual precipitation of 1,400mm, NPP at the study site was constrained by the amount of water available for the vegetation. Such a modeling result should be verified by the field measurements.

• Journal of Biomedical Engineering Research
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• v.38 no.1
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• pp.43-48
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• 2017

Chemotherapy, radiation therapy, and surgery are major methods to treat cancer. However, current cancer treatments report severe side effects and high recurrences. Recent studies about engineering nanoparticles as a drug carrier suggest possibilities in terms of specific targeting and spatiotemporal release of drugs. While many nanoparticles demonstrate lower toxicity and better targeting results than free drugs, they still need to improve their performance dramatically in terms of targeting accuracy, immune responses, and non-specific accumulation at organs. One possible way to overcome the challenges is to make precisely controlled nanoparticles with respect to size, shape, surface properties, and mechanical stiffness. Here, we demonstrate $500{\times}200nm$ discoidal polymeric nanoconstructs (DPNs) as a drug delivery carrier. DPNs were prepared by using a top-down fabrication method that we previously reported to control shape as well as size. Moreover, DPNs have multiple payloads, poly lactic-co-glycolic acid (PLGA), polyethylene glycol (PEG), lipid-Rhodamine B dye (RhB) and Salinomycin. In this study, we demonstrated a potential of DPNs as a drug carrier to treat cancer.

• Journal of Cadastre & Land InformatiX
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• v.50 no.1
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• pp.231-245
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• 2020

The purpose of this study was to analyze the spatiotemporal characteristics of staying places by deriving the main staying places of the elderly population in Seoul using public transportation card data. For this reason, we used public transportation card data for 7 days from October 12, 2015 to October 18, 2015. As a result of the analysis, 14 places were extracted as the main staying places. It was divided into 5 groups based on the characteristics of the visiting users and concentration time. Most of the staying places showed that the elderly users who lived near the places visited, but in the case of the group where a large number of elderly users visited had relatively wide range of residential distribution. It was possible to confirm that there was a hierarchy. And the concentration time was displayed differently. Most of the staying places' concentration time was between 10 am and 5 pm. However, in the case of Jegi-dong group and Jamsil group had different concentration time. The results of this research provide necessary suggestions for establishing a public transport policy that considers the main stay spaces of the elderly population in Seoul and the stay characteristics of each stay space.

• Korean Journal of Optics and Photonics
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• v.28 no.5
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• pp.236-240
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• 2017

In this paper, we investigate the thermal response of skin tissue to high-intensity focused ultrasound (HIFU) by means of infrared (IR) thermal imaging. For skin tightening, a 7-MHz ultrasound transducer is used to induce irreversible tissue coagulation in porcine skin. An IR camera is employed to monitor spatiotemporal changes of the temperature in the tissue. The maximum temperature in the tissue increased linearly with applied energy, up to $90^{\circ}C$. The extent of irreversible tissue coagulation (up to 3.2 mm in width) corresponds well to the spatial distribution of the temperature during HIFU sonication. Histological analysis confirms that the temperature beyond the coagulation threshold (${\sim}65^{\circ}C$) delineates the margin of collagen denaturation in the tissue. IR thermal imaging can be a feasible method for quantifying the degree of thermal coagulation in HIFU-induced skin treatment.

• Korean Journal of Remote Sensing
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• v.37 no.5_3
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• pp.1405-1423
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• 2021

Precipitation is one of the main factors that affect water and energy cycles, and its estimation plays a very important role in securing water resources and timely responding to water disasters. Satellite-based quantitative precipitation estimation (QPE) has the advantage of covering large areas at high spatiotemporal resolution. In this study, machine learning-based rainfall intensity models were developed using Himawari-8 Advanced Himawari Imager (AHI) water vapor channel (6.7 ㎛), infrared channel (10.8 ㎛), and weather radar Column Max (CMAX) composite data based on random forest (RF). The target variables were weather radar reflectivity (dBZ) and rainfall intensity (mm/hr) converted by the Z-R relationship. The results showed that the model which learned CMAX reflectivity produced the Critical Success Index (CSI) of 0.34 and the Mean-Absolute-Error (MAE) of 4.82 mm/hr. When compared to the GeoKompsat-2 and Precipitation Estimation from Remotely Sensed Information Using Artificial Neural Networks (PERSIANN)-Cloud Classification System (CCS) rainfall intensity products, the accuracies improved by 21.73% and 10.81% for CSI, and 31.33% and 23.49% for MAE, respectively. The spatial distribution of the estimated rainfall intensity was much more similar to the radar data than the existing products.