• Journal of the Korea Computer Industry Society
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• v.7 no.4
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• pp.427-436
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• 2006

State-space method for the analysis of the dynamic characteristics of a body motion is set up as mathematical tool for the solution of differential equation by computer. Representation of a system is described as a simple form of matrix calculation and unique form of model is available for the linear or nonlinear, time variant or time invariant, mono variable or multi variable system etc. For the analysis of state-space method a complicated vector calculation is required, but this analysis can be simplified with the specific functions of a software package. Recently as the Graphical User Interface softwares are well-developed, then it is very simplified to execute the simulation of the dynamic characteristics for the state-space model with the interactive graphics treatment. The purpose of this study is to developed the simulator for the educational analysis of the dynamic characteristics of body motion, and for the analysis of the longitudinal dynamic characteristics of an aircraft that is primarily to design the simulator for the analysis of the transient response of an aircraft longitudinal stability.

• Journal of Yeungnam Medical Science
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• v.2 no.1
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• pp.253-258
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• 1985

The congenital tracheoesophageal fistula without atresia of the esophagus is considered a rare variant, and the literature concerned to the tracheoesophageal fistula without atresia, is little in adult especially. The 22-year-old male was admitted to Yeungnam University Hospital with his chief complaints of weight loss (6kg/6 months), abdominal discomfort, and intermittent coughing. The diagnosis was made by the endoscopy and esophagography. The fistula was 1.5cm in diameter, 0.5cm in length. The level was around second thoracic vertebra. The operation was performed transpleurally through the right third intercostal space and the fistula was secured with interrupted silk suture after division. The fibrotic adhesion was seen around the tracheoesophageal fistula. The postoperative course was uneventful, and postoperative esophagogram revealed ho extraluminal leakage. Herewith we report this unusual case of isolated tracheo-esophageal fistula with review of literatures.

• Journal of the Society of Naval Architects of Korea
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• v.46 no.4
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• pp.382-390
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• 2009

The submerged body near the free surface is disturbed by the 1st and 2nd order wave forces, which results in unstable movements when no control is applied. In this paper, the vertical motions of the submerged body are analyzed, and the time-variant nonlinear system for the vertical motions of the submerged body is transformed to the time-invariant linear system in state space. Next, depth controller of the submerged body is designed by using LQR control, one of the modern optimal control technique. Numerical simulation shows that effective depth controls can be achieved by LQR control.

• Nuclear Engineering and Technology
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• v.55 no.2
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• pp.421-431
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• 2023

Nuclear power plants (NPPs) have technical specifications (Tech Specs) to ensure that the equipment and key operating parameters necessary for the safe operation of the power plant are maintained within limiting conditions for operation (LCO) determined by a safety analysis. The LCO of Tech Specs that identify the lowest functional capability of equipment required for safe operation for a facility must be complied for the safe operation of NPP. There have been previous studies to aid in compliance with LCO relevant to rule-based expert systems; however, there is an obvious limit to expert systems for implementing the rules for many situations related to LCO. Therefore, in this study, we present a retrieval methodology for similar LCO cases in determining whether LCO is met or not met. To reflect the natural language processing of NPP features, a domain dictionary was built, and the optimal term frequency-inverse document frequency variant was selected. The retrieval performance was improved by adding a Boolean retrieval model based on terms related to the LCO in addition to the vector space model. The developed domain dictionary and retrieval methodology are expected to be exceedingly useful in determining whether LCO is met.

• Journal of the Korean Operations Research and Management Science Society
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• v.36 no.4
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• pp.91-107
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• 2011

The importance of service industries is growing as the portion of the service sector increases fast in the recent decades. This research deals with service prototyping and testing in a service laboratory. While products are generally tested through prototyping in new product development processes, services are difficult to test because of the characteristic of service, intangibility. A service laboratory, named s-Scape, is the experiment environment which has been developed to test services in virtual space for the purpose of analysis and improvement of real-world services such as hospitals and automobile show rooms. In this research, we present a service prototyping tool and language to support service test in the service laboratory. We first analyze key elements of service prototypes, and then design the service prototype diagram (SPD) and the service prototype description language (SPDL). SPD, which is a variant of the service blueprint, is a graphical tool to be used to generate SPDL. SPDL is an executable language of describing a service prototype of a real-world service in extensible markup language (XML) to experiment the service environment in virtual space. SPD reflects the control and interface of virtual reality devices, as well as key elements of service modeling. SPD represents a service process in which service providers and customers interact with each other in a service scape.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.15 no.5
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• pp.444-450
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• 2004

In mobile communications environment, STBC-OFDM(Space Time Block Code-Orthogonal Frequency Division Multiplexing) system with transmit diversity obtains the MRRC(Maximal Ratio Receiver Combining) diversity gain in time-invariant channel between two received symbols. But in time-variant channel, due to the interference between received symbols, MRRC diversity gain cant be obtained. So, when the mobile device with transmit diversity moves in high speed, the scheme to reduce the performance degradation due to the interference is needed. In this paper, we propose the receiver architecture with advanced transmit diversity, which improves the performance of STBC-OFDM system. The proposed architecture obtains the diversity gain without the change of transmit bandwidth at the receiver with the interference canceller using ZF(Zero Forcing) algorithm. Simulation results show performance improvement as doppler shift is increasing.

• Journal of the Korean Institute of Intelligent Systems
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• v.22 no.3
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• pp.281-286
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• 2012

In the growing standard of people's lives, we want desire to create eco-friendly water space what is called the Green Technology that is in the limelight. These green space is introduced the cultural contents and we use the water, music, and nature as tool of emotional verbalism. Presently, when we want to make scenario, water landscape scenario is made by director. but these systems have some disadvantages as the cost and limitation of direction. There is a growing interest in the integrated control system based on PC and Internet. In this paper, it is about fountain control system. Previous research area was only one using programmable logic controller or industrial PC. we proposed the development of intelligent green fountain culture system for healthy emotional self-concept. And we made automatic weather sensing system that is designed by the intelligent green fountain culture system to estimate the time-variant system.

• Microbiology and Biotechnology Letters
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• v.49 no.2
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• pp.148-156
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• 2021

Single-chain antibodies against epidermal growth factor receptor variant III (EGFRvIII) are potentially promising agents for developing antibody-based cancer treatment strategies. We described in our previous study the successful expression of an anti-EGFRvIII scFv antibody in Escherichia coli. However, we could also observe the formation of insoluble aggregates in the periplasmic space, limiting the production yield of the active product. In the present study, we investigated the mechanisms by which growth conditions could affect the expression of the soluble anti-EGFRvIII scFv antibody in small-scale E. coli NiCo21(DE3) cultures, attempting to maximize production. The secreted scFv molecules were purified using Ni-NTA magnetic beads and protein characterization was performed using SDS-PAGE and western blot analyses. We used the ImageJ software for protein quantification and determined the antigen-binding activity of the scFv antibody against the EGFRvIII protein. Our results showed that the highest percentage of soluble scFv expression could be achieved under culture conditions that combined low IPTG concentration (0.1 mM), low growth temperature (18℃), and large culture dish surface area. We found moderate-yield soluble scFv production in the culture medium after lactose-mediated induction, which was also beneficial for downstream protein processing. These findings were confirmed by conducting western blot analysis, indicating that the soluble, approximately 30-kDa scFv molecule was localized in the periplasm and the extracellular space. Moreover, the antigen-binding assay confirmed the scFv affinity against the EGFRvIII antigen. In conclusion, our study reveals that low-speed protein expression is preferable to obtain more soluble anti-EGFRvIII scFv protein in an E. coli expression system.

• The Korean Journal of Applied Statistics
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• v.37 no.1
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• pp.103-118
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• 2024

The horseshoe prior is notably one of the most popular priors in sparse regression models, where only a small fraction of coefficients are nonzero. The parameter space of the horseshoe prior is much smaller than that of the spike and slab prior, so it enables us to efficiently explore the parameter space even in high-dimensions. However, on the other hand, the horseshoe prior has a high computational cost for each iteration in the Gibbs sampler. To overcome this issue, various MCMC algorithms for the horseshoe prior have been proposed to reduce the computational burden. Especially, Johndrow et al. (2020) recently proposes an approximate algorithm that can significantly improve the mixing and speed of the MCMC algorithm. In this paper, we compare (1) the traditional MCMC algorithm, (2) the approximate MCMC algorithm proposed by Johndrow et al. (2020) and (3) its variant in terms of computing times, estimation and variable selection performance. For the variable selection, we adopt the sequential clustering-based method suggested by Li and Pati (2017). Practical performances of the MCMC methods are demonstrated via numerical studies.

• Korean Journal of Clinical Laboratory Science
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• v.53 no.2
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• pp.143-150
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• 2021

The recent spread of novel and highly variant pathogenic viruses, including the coronavirus (SARS-CoV-2), has increased the demand for diagnostic testing for rapid confirmation. This has resulted in investigating the functional capability of each space, and preparing facility guidelines to secure the safety of medical technologists. During viral evaluations, there is a requirement of negative pressure facilities along with thread separation, during pre-treatment of samples and before nucleic acid amplification. Space composition therefore needs to be planned by considering unidirectional air flow. This classification of safety management facilities is designated as biosafety level 2, and personal protective equipment is placed accordingly. In case of handling dangerous materials, they need to be carried out of the biosafety cabinet, and sterilizers are required for suitable disposal of infectious agents. A common feature of domestic laboratories is maintenance of the sample pre-treatment space at a negative pressure of -2.5 Pa or less, and arranging separate pre-treatment and reagent preparation spaces during the test process. We believe that the data generated in this study is meaningful, and offers an efficient direction and detailed flow for separation of the inspection process and space functions. Moreover, this study introduces construction of the laboratory by applying the safety management standards.