• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제41권4호
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• pp.176-180
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• 2015

Objectives: The increased prevalence of antibiotic resistance is an outcome of evolution. Most patients presenting with odontogenic space infections also have associated systemic co-morbidities such as diabetes mellitus resulting in impaired host defense. The present study aims to compare the odontogenic spaces involved, antibiotic susceptibility of microorganisms, length of hospital stay, and the influence of systemic comorbidities on treatment outcome in diabetic patients. Materials and Methods: A 2-year prospective study from January 2012 to January 2014 was conducted on patients with odontogenic maxillofacial space infections. The patients were divided into two groups based on their glycemic levels. The data were compiled and statistically analyzed. Results: A total of 188 patients were included in the study that underwent surgical incision and drainage, removal of infection source, specimen collection for culture-sensitivity, and evaluation of diabetic status. Sixty-one out of 188 patients were found to be diabetic. The submandibular space was the most commonly involved space, and the most prevalent microorganism was Klebsiella pneumoniae in diabetics and group D Streptococcus in the nondiabetic group. Conclusion: The submandibular space was found to be the most commonly involved space, irrespective of glycemic control. Empiric antibiotic therapy with amoxicillin plus clavulanic acid combined with metronidazole with optimal glycemic control and surgical drainage of infection led to resolution of infection in diabetic as well as nondiabetic patients. The average length of hospital stay was found to be relatively longer in diabetic individuals.

• Journal of Forest and Environmental Science
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• 제33권4호
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• pp.322-329
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• 2017

As a result of contemporary environmental concerns, a number of studies from plants' tissues as one of the alternatives to conventional chemicals are increasingly investigated. In tandem with these trends, Lagenaria breviflora (LB) fruit, reputed as antiviral and depilatory agents in the Yoruba folkloric medicine was examined on Vitex doniana wood to ascertain its antifungal activity. Fungicides of 25%, 50%, 75%, and 100% LB fruits formulations (concentrations) were developed through simple one-step mechanical-forming process, including control. In this study, the yield, the chemical compositions, the absorption capacity of the fungicides and wood weight losses (WWL) analysis were evaluated to investigate the antifungal activity of LB fruit on wood. The fruit extract yielded 35.4% of fresh juice weight. LB fruits contained total: alkaloids ($8.78{\pm}0.21mg/mL$), flavonoids ($2.01{\pm}0.02mg/mL$), phenol ($7.42{\pm}0.09mg/mL$), saponins ($11.00{\pm}0.10mg/mL$) and tannins ($5.47{\pm}0.05mg/mL$) contents. All the formulations provided effective protection against the tested wood fungi compared to control. Interestingly, the antifungal activity of 50% and 25% formulations of 6.8% WWL and 9.9% WWL satisfied the excellent fungal resistance class description against white rot fungus (Ganoderma lucidum) and brown rot fungus (Fibroporia vaillantii), respectively according to ASTM D 2017. These results thus, support LB fruit as a strong potential source of natural antifungals for industrial wood production.

• 한국광학회지
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• 제20권5호
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• pp.294-300
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• 2009

테라헤르츠 광원인 포토믹서의 출력을 향상시키기 위하여 강한 공진의 복사부와 안정적인 DC 급전부로 구성된 네잎클로버 형태의 새로운 안테나구조를 제안하였다. 먼저 복사환경을 단순화시킨 무한기판 위에서 제안한 안테나구조의 공진특성을 살펴보았고, 이를 바탕으로 제안한 구조가 확장형 반구렌즈 위에서 최대의 전체효율과 지향성을 지니도록 설계하였다. 기존의 전파장다이폴안테나와 비교한 결과, 제안한 구조는 공진주파수에서 6배 이상의 높은 입력임피던스 특성을 가짐으로써 포토믹서와의 부정합효율을 크게 개선시켰으며, 이로 인해 테라헤르츠 출력이 전파장 다이폴의 경우보다 2.7배 높게 예상되었다.

• 멤브레인
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• 제21권4호
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• pp.351-359
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• 2011

For advanced drinking water treatment of high turbidity water, we used the hybrid process that was composed of photocatalyst packing in space of between outside of multi-channel ceramic microfiltration membrane and membrane module inside. Photocatalyst was polypropylene (PP) beads coated $TiO_2$ powder by CVD (chemical vapor deposition) process. Instead of natural organic matters (NOM) and fine inorganic particles in natural water source, standard NOM solution was prepared with humic acid and kaolin. Water-back-flushing of 10 sec was performed per every period of 10 min to minimize membrane fouling. Resistance of membrane fouling ($R_f$) increased and J decreased as concentration of humic acid changed from 2 mg/L to 10 mg/L, and finally the highest total permeate volume ($V_T$) could be obtained at 2 mg/L. Then, treatment efficiency of turbidity and $UV_{254}$ absorbance were above 96.4% and 78.9%, respectively. As results of treatment portions by membrane filtration, photocatalyst adsorption, and photo-oxidation in (MF), (MF + $TiO_2$), (MF + $TiO_2$ + UV) processes, turbidity was treated little by photocatalyst adsorption, and photo-oxidation. However, treatment portions of $UV_{254}$ absorbance by adsorption (MF + $TiO_2$) and photo-oxidation (MF + $TiO_2$ + UV) at humic acid of 4 mg/L and 6 mg/L were above 9.0, 9.5 and 8.1, 10.9%, respectively.

• 한방재활의학과학회지
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• 제28권2호
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• pp.21-35
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• 2018

Objectives The objective of this study is to determine the antimicrobial effect of Daehwanggyeonu-san(Dahwangqianniu-san,DGE) and synergistic effects with antibiotics oxacillin, ampicillin, and gentamicin against Methicillin-Resistant Staphylococcus aureus(MRSA). Methods The antibacterial activity of DGE extract was evaluated againest MRSA strains by using the Disc diffusion method, broth microdilution method(minimal inhibitory concentration; MIC), checkerboard dilution test. The checkerboard dilution test was used to examined synergetic effect of oxacillin, ampicillin, gentamicin, ciprofloxacin with DGE extract. Results DGE showed antimicrobial activity against MRSA with an MIC value of $125{\sim}250{\mu}g/mL$. In the checkerboard test, the interation of DGE with all tested antibiotics produced almost synergy or partial synergy against MRSA. Conclusions This study shows that DGE reduced the MICs of several antibiotics tested, and a remarkable antibacterial effect of DGE, with membrane permeability enhancers and ATP synthase inhibitors. This study can be a valuable source for the development of a new drug with low MRSA resistance.

• 한국정보통신학회논문지
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• 제22권7호
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• pp.993-1000
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• 2018

본 논문에서는 셀프-캐스코드 구조를 이용한 LDO 레귤레이터를 제안하였다. 셀프-캐스코드 구조의 소스 측 MOSFET의 채널 길이를 조절하고, 드레인 측 MOSFET의 바디에 순방향 전압을 인가함으로써 최적화하였다. 오차 증폭기 입력 차동단의 셀프-캐스코드 구조는 높은 트랜스컨덕턴스를 가지도록, 출력단은 높은 출력 저항을 가지도록 최적화하였다. 제안 된 LDO 레귤레이터는 $0.18{\mu}m$ CMOS 공정을 사용하였고, SPECTERE를 이용하여 시뮬레이션 되었다. 제안 된 셀프-캐스코드 구조를 이용한 LDO 레귤레이터의 로드 레귤레이션은 0.03V/A로 기존 LDO의 0.29V/A보다 급격하게 개선되었다. 라인 레귤레이션은 2.23mV/V로 기존 회로보다 약 3배 향상되었다. 안정화 속도는 625ns로 기존 회로보다 346ns 개선되었다.

• 전력전자학회논문지
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• 제14권1호
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• pp.72-81
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• 2009

본 논문에서는 대기압 플라즈마 발생용 정현파펄스형 교류 전원 장치에 대한 연구를 진행하였다. 정현파펄스형 전원장치는 기존의 LC공진을 이용한 교류 전원장치보다 높은 dv/dt를 갖게 되므로 안정적인 플라즈마 공급이 가능하며 펄스형에 비해 고조파 노이즈가 적고, 정전류 턴온-영전압 턴오프 형태로 동작하므로 매우 높은 효율을 갖는다. 또한 플라즈마 점화 기능을 강화하고 안정적인 전압제어를 위해 3상 부스트형 컨버터를 입력단에 사용하여 입력 역률이 매우 높은 시스템을 구성할 수 있다. 실험실 수준의 10kW부하시설을 사용하여 본 연구의 결과를 입증하였다.

• 한국가구학회지
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• 제27권1호
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• pp.8-14
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• 2016

Increasing concerns of environment need to make change furniture field to more environmentally friendly approach, such as reuse of by-products from wooden products. As it is, the methods of recycling wood for industrial purposes have the advantage of productivity and adaptability. However, the industrial way is required a certain production facility of processing wooden by-products and has possible hygienic problems due to contaminated sources. Many designers have developed their own methods for reuse of wood in unique and artistic ways. Even so, because of confined sources, it could be not enough supply. Therefore, I developed the design methodology utilizing wooden by-products from S Design Company to relieve former ways' problems. The design suggestion took materials from a safe and abundant source. The wooden leftover pieces were connected together with epoxy clay, so previous process traces of furniture are remained as a decorative factor. Moreover, the synthesized material was able to be processed by ordinary woodworking facilities without additional installations. In doing so, console table focused on a commercial purpose and dining table for an artistic objective were successfully fabricated as final suggestions. In consideration of the proposal using wooden furniture leftovers, diverse recycling designs should be investigated for future reference.

• Journal of Microbiology and Biotechnology
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• 제27권9호
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• pp.1576-1585
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• 2017

Yeasts, filamentous fungi, and bacteria colonize the surface of fermented sausages during the ripening process. The source of this microbiota is their surrounding environment, and is influenced by the maturing conditions and starter cultures. Debaryomyces hansenii was previously isolated from several dry-cured meat products and associated with the lipolytic and proteolytic changes that occur in these products, influencing their taste and flavor. Therefore, this study isolated the yeast microbiota present in the casing from different meat products ("lomo," "chorizo," and "$salchich{\acute{o}}n$") from the Valle de los Pedroches region in southern Spain. D. hansenii was by far the most abundant species in each product, as all 22 selected isolates were identified as D. hansenii by biochemical and/or molecular methods. In contrast, no yeasts were found in the meat batter. These data constitute the first study of the yeasts present in "lomo" sausages and particularly the highly appreciated Valle de los Pedroches "lomo" sausages. Furthermore, the resistance of these isolates to different pHs, temperatures, and saline stress was studied, together with their catabolic characteristics. Based on the results, certain isolates are proposed as valuable candidate starter cultures that could improve both the manufacture and the flavor of such dry-cured meat products, and provide an understanding of new mechanisms involved in stress tolerance. Applied medium-scale industrial tests are currently in progress.

• 분석과학
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• 제17권1호
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• pp.37-44
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• 2004

효모 Hansenula polymorpha 로부터 탄소원으로 0.5% 메탄올을 이용하여 알코올 산화효소를 대량 유도 발현하였다. 발현 유도된 Hansenula polymorpha 알코올 산화효소는 두 단계의 컬럼 크로마토그래피를 통하여 전기영동에서 단일밴드로 정제하였다. 정제한 효소는 주로 일차 지방족 알코올을 산화시키며, 에탄올에 대해 가장 높은 기질특이성을 보였다. 이 효소가 촉매하는 에탄올 산화반응의 최적 pH는 8.5 이였으며, 최적 온도는 $50^{\circ}C$를 나타내었다. 효소의 $T_m$ 값은 약 $52^{\circ}C$ 이었으며, $65^{\circ}C$에서도 완전히 불활성화 되지 않았다. 또한 효소는 변성제와 7주간의 비교적 장기간 보전에 대해서도 안정하였다. 이 효소는 알코올 측정을 위한 효소학적 방법 및 알코올과 알데히드의 공업적 생산에 이용될 수 있다.