• Journal of dental hygiene science
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• v.23 no.4
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• pp.369-377
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• 2023

Background: In this study, we investigated the potential use of keratin for oral tissue regeneration. Keratin is well-known for its effectiveness in skin regeneration by promoting keratinization and enhancing the elasticity and activity of fibroblasts. Because of its structural stability, high storability, biocompatibility, and safety in humans, existing research has predominantly focused on its role in skin wound healing. Herein, we propose using keratin proteins as biocompatible materials for dental applications. Methods: To assess the suitability of alpha-keratin protein as a substrate for cell culture, keratin was extracted from human hair via PEGylation. Viabilities of primary human gingival fibroblasts (HGFs) and human oral keratinocytes (HOKs) were assessed. Fluorescence immunostaining and migration assays were conducted using a fluorescence microscope and confocal laser scanning microscope. Wound healing and migration assays were performed using automated software to analyze the experimental readout and gap closure rate. Results: We confirmed the extraction of alpha-keratin and formation of the PEG-g-keratin complex. Treatment of HGFs with keratin protein at a concentration of 5 mg/ml promoted proliferation and maintained cell viability in the test group compared to the control group. HOKs treated with 5 mg/ml keratin exhibited a slight decrease in cell proliferation and activity after 48 hours compared to the untreated group, followed by an increase after 72 hours. Wound healing and migration assays revealed rapid closure of the area covered by HOKs over time following keratin treatment. Additionally, HOKs exhibited changes in cell morphology and increased the expression of the mesenchymal marker vimentin. Conclusion: Our study demonstrated the potential of hair keratin for soft tissue regeneration, with potential future applications in clinical settings for wound healing.

• Journal of Internet Computing and Services
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• v.24 no.6
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• pp.99-105
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• 2023

In the 4th industrial revolution, the field of criminal justice is paying attention to Legaltech using artificial intelligence to provide efficient legal services. This paper attempted to create a crime prediction model that can apply Recurrent Neural Network(RNN) to increase the potential for using legal technology in the domestic criminal justice field. To this end, the crime process was divided into pre, during, and post stages based on the criminal facts described in the judgment, utilizing crime script analysis techniques. In addition, at each time point, the method and evidence of crime were classified into objects, actions, and environments based on the sentence composition elements and the 8 principles of investigation. The case summary analysis framework derived from this study can contribute to establishing situational crime prevention strategies because it is easy to identify typical patterns of specific crime methods. Furthermore, the results of this study can be used as a useful reference for research on generating crime situation prediction data based on RNN models in future follow-up studies.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.34 no.4
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• pp.192-203
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• 2023

Digital therapeutics based on software, such as artificial intelligence, virtual reality, games, and smartphone applications, are in the spotlight as new therapeutic alternatives in child and adolescent psychiatry. It draws attention to overcoming conventional therapeutics' limitations, such as toxicity, cost, and accessibility, and encourages patients to participate in the treatment attractively. The growth potential of the digital therapeutics market for psychiatric disorders in children and adolescents in Korea and abroad has been highlighted. Clinical studies and Food and Drug Administration approvals for digital therapeutics have increased, and cases approved by the Ministry of Food and Drug Safety have emerged in Korea. As seen above, digital transformation in child and adolescent psychiatry will change treatment paradigms significantly. Therefore, as this new field has just begun to emerge, it is necessary to verify the effectiveness and scope of the application of digital therapeutics and consider preparing a compensation system and institutional arrangements. Accordingly, this study analyzed the development trends and application status of digital therapeutics in children and adolescents and presented limitations and development directions from the perspective of application in healthcare. Further, the study is expected to identify the utility and limitations of digital therapeutics for children and adolescents and establish effective application measures.

• Journal of Korean Physical Therapy Science
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• v.30 no.3
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• pp.49-58
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• 2023

Background: This study aims to examine the useful- ness of the portable spirometer "The Spirokit" as a clinical diagnostic device through technology introduction, precision test, and correction. Design: Technical note Methods: "The Spirokit" was developed using a propeller-type flow rate and flow rate measurement method using infrared and light detection sensors. The level of agreement between the Pulmonary Waveform Generator and the measured values was checked to determine the precision of "The Spirokit", and the correction equation was included using the Pulmonary Waveform Generator software to correct the error range. The analysis was requested using the ATS 24/26 waveform recognized by the Ministry of Food and Drug Safety and the American Thoracic Society for the values of Forced Voluntary Capacity (FVC), Forced Expiratory Volume in 1second (FEV1), and Peak Expiratory Flow (PEF), which are used as major indicators for pulmonary function tests. All tests were repeated five times to derive an average value, and FVC and FEV1 presented accuracy and PEF presented accuracy as the result values. Results: FVC and FEV1 of 'The Spirokit' developed in this study showed accuracy within ± 3% of the error level in the ATS 24 waveform. The PEF value of 'The Spirokit' showed accuracy within the error level ± 12% of the ATS 26 waveform. Conclusion: Through the results of this study, the precision of 'The Spirokit' as a clinical diagnosis device was identified, and it was confirmed that it can be used as a portable pulmonary function test that can replace a spirometer.

• Journal of Society of Preventive Korean Medicine
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• v.28 no.1
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• pp.31-42
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• 2024

Objective : In order to understand the changes in domestic approval regulations applicable to traditional Korean medical device companies, this article will explain the major amendments 「Regulation on Medical Device Approval Report Review, etc.」 from 2005 to the present on a year-by-year basis, and provide a counter plan to the recent changes in approval regulations. Methods : We analysed the changes in approval regulatory amendments related to the traditional Korean medical devices from 2005 to the present. Results : The Ministry of Food and Drug Safety is continuously improving medical device approval regulations to ensure the global competitiveness of domestic medical devices and contribute to the improvement of public health. Recent major approval regulatory amendments include the establishment of a review system for software medical devices and digital therapeutics, the recognition of real world evidence materials, the introduction of a biological evaluation of medical devices within a risk management process and a medical device approval licence renewal system. Conclusions : It is expected that the range of medical devices available to Korean medicine doctors will continue to expand in the future through the provision of non-face-to-face medical services and the development of advanced and new medical devices, as well as wearable medical devices and digital therapeutics. In order to increase the market entry potential of traditional Korean medical devices that incorporate advanced technologies such as digital technology and AI-based diagnosis and prediction technology, it is urgent that the government provide significant support to traditional Korean medical device companies to improve approval regulatory compliance.

• Journal of Internet Computing and Services
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• v.25 no.2
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• pp.113-122
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• 2024

Recently, cutting-edge ICT technologies such as artificial intelligence, blockchain, edge computing, and the Internet of Things have been applied in various fields to create new services and a new digital era. Along with these technological developments, various policies are being implemented in Korea to transform the country from a "Smart City" to a "Platform City". We can create new services and values by linking with the Smart City Integrated Platform and Smart Housing Platform. This paper defines a linkage scenario between a Smart Housing Platform and the Smart 119 Emergency Dispatch Support Service, one of the Smart City Safety Nets. We propose a data transmission protocol and a metadata schema for data exchange between the Smart Housing Platform and the Smart City Integrated Platform to provide the Smart 119 Emergency Dispatch Support Service.

• Journal of Internet Computing and Services
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• v.25 no.2
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• pp.11-19
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• 2024

This paper was studied abouta technology for detecting damage to temporary works equipment used in construction sites with explainable artificial intelligence (XAI). Temporary works equipment is mostly composed of steel or aluminum, and it is reused several times due to the characters of the materials in temporary works equipment. However, it sometimes causes accidents at construction sites by using low or decreased quality of temporary works equipment because the regulation and restriction of reuse in them is not strict. Currently, safety rules such as related government laws, standards, and regulations for quality control of temporary works equipment have not been established. Additionally, the inspection results were often different according to the inspector's level of training. To overcome these limitations, a method based with AI and image processing technology was developed. In addition, it was devised by applying explainableartificial intelligence (XAI) technology so that the inspector makes more exact decision with resultsin damage detect with image analysis by the XAI which is a developed AI model for analysis of temporary works equipment. In the experiments, temporary works equipment was photographed with a 4k-quality camera, and the learned artificial intelligence model was trained with 610 labelingdata, and the accuracy was tested by analyzing the image recording data of temporary works equipment. As a result, the accuracy of damage detect by the XAI was 95.0% for the training dataset, 92.0% for the validation dataset, and 90.0% for the test dataset. This was shown aboutthe reliability of the performance of the developed artificial intelligence. It was verified for usability of explainable artificial intelligence to detect damage in temporary works equipment by the experiments. However, to improve the level of commercial software, the XAI need to be trained more by real data set and the ability to detect damage has to be kept or increased when the real data set is applied.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.24 no.1
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• pp.197-205
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• 2024

Development of AI and big data-based algorithms to advance and optimize the recognition and detection performance of various static/dynamic vehicles in front and around the vehicle at a time when securing driving safety is the most important point in the development and commercialization of autonomous vehicles. etc. are being studied. However, there are many research cases for recognizing the same vehicle by using the unique advantages of radar and camera, but deep learning image processing technology is not used, or only a short distance is detected as the same target due to radar performance problems. Therefore, there is a need for a convergence-based vehicle recognition method that configures a dataset that can be collected from radar equipment and camera equipment, calculates the error of the dataset, and recognizes it as the same target. In this paper, we aim to develop a technology that can link location information according to the installation location because data errors occur because it is judged as the same object depending on the installation location of the radar and CCTV (video).

• Journal of Advanced Navigation Technology
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• v.27 no.6
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• pp.798-803
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• 2023

In the industrial internet of things (IIoT) industry, including smart factories, there are many cases where electronic devices are complexly combined and installed due to the recent development of intelligent information technology. Electromagnetic waves generated from such complex facilities affect other devices and services, which can lead to safety issues. The problem such as electromagnetic interference (EMI) and electromagnetic compatibility (EMC) generated when controlling complex facilities is an essential element that must be solved, and the engineering basis for EMI and EMC must be established to foster the industry of complex facilities. Therefore, in this study, EMC & EMI engineering demonstration cases for solar power fixed facilities using the national standard guideline have been analyzed. The results show that the electromagnetic risk indices in the solar power facilities have been degraded up to control level, and a national EMC engineering system has been proposed for complex facilities.

• Information Systems Review
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• v.18 no.3
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• pp.137-153
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• 2016

Organizations depend on smart working environments, such as mobile networks. This development motivates companies to focus on information security. Information leakage negatively affects companies. To address this issue, management and information security researchers focus on compliance of employees with information security policies. Countermeasures in information security are known antecedents of intention to comply information security policies. Despite the importance of this topic, research on the antecedents of information security countermeasures is scarce. The present study proposes information security intelligence as an antecedent of information security countermeasures. Information security intelligence adapted the concept of safety intelligence provided by Kirwan (2008). Information security intelligence consists of problem solving skills, social skills, and information security knowledge related to information security. Results show that problem solving skills and information security knowledge have positive effects on the awareness of employees of information security countermeasures.