In this paper, the development of a manually and continuously variable impact force control mechanism for hydraulic breakers was studied. Generally, a hydraulic breaker has one or two piston strokes. Hydraulic breakers, which have two strokes, have two valve-switching ports and make short and long piston strokes. The piston stroke valve controls the piston stroke by opening and closing a short stroke-switching port. The short piston stroke mode is used to break soft rock, concrete, or asphalt. This stroke control valve system is not popular for small hydraulic breakers mounted on 1 to 14-ton excavators. To preserve the carrier-like excavator, proper breaking force is needed, and it can be easily controlled by multiple piston stroke control valves. The easiest way to control these breakers is to use several switching ports and valves but they are not easy to install in small hydraulic breakers and are expensive. To use only one switching port and valve, a method can be used to change the open area of the switching port to delay valve switching. This method provides multiple piston strokes.
Components of dental resin-based restorative materials are reported to leach from the filling materials even after polymerization. Hydroquinone (HQ) is one of the major monomers used in the dental resin and is known as a carcinogen. Thus, carcinogenic risk of HQ leaching from the dental resin becomes a public health concern. The present study attempted to examine the carcinogenic potentials of HQ on the human epithelial cell, which is the target cell origin of the most of oral cancers. Cytotoxicity of HQ was observed above 50${\mu}M$ as measured by LDH assay, indicating a relatively low toxicity of this substance in human epithelial cells. The parameters of neoplastic cellular transformation such as cell saturation density, soft agar colony formation and cell aggregation were analyzed to examine the carcinogenic potential of HQ. The study showed that 2-week exposure of HQ showed the tendency of increase in the saturation density and the significant enhancement of soft agar colony formation at the highest dose, 50 ${\mu}M$ only. It is suggested that HQ has a weak potential of carcinogenicity. When cells were treated with HQ and TPA, a well-known tumor promoter, the parameters of neoplastic cellular transformation was significantly increased. This result indicates that the potential risk of carcinogenicity from HQ is largely dependent upon the presence of promoter. Exposure of 50 ${\mu}M$ HQ increased the time-dependent apoptosis as measured by the ELISA kit. This concentration coincides with a dose of neoplastic transformation, indicating a possible link between apoptosis and HQ-induced cellular transformation. Hydroquinone generated Reactive Oxygen Species (ROS) which was evidenced by the treatment of antioxidants such as trolox and N-acetyl cysteine and the GSH depleting agent, BSO. Antioxidants blocked the generation of ROS and the GSH depleting agent, BSO dramatically increased the ROS production. Since HQ is known to increase ROS production thru activation of transcriptional factor such as c-Myb and Pim-1, it is speculated that ROS generation by HQ plays a role in the activation of oncogene, which may lead to neoplastic transformation. In addition, ROS is involved in the alteration of signal transduction, which regulates the apoptosis in many cellular systems. Thus, ROS-mediated apoptosis may be involved in the HQ-induced carcinogenic processes. Protein kinase C (PKC) is known to play pivotal roles in neoplastic transformation of cells and its high expression is often found in a variety of types of tumors including oral cancer. PKC translocation of PKC-${\alpha}$ was observed following HQ exposure. Altered signaling system may also play a role in the transformation process. Taken together, HQ leached from the dental resin does not pose a significant threat as a cancer causing agent, but its carcinogenic potential can be significantly elevated in the presence of promoter. The mechanism of HQ-induced carcinogenesis involved ROS generation, apoptosis and altered signaling pathway. The present study will provide a valuable data to estimate the potential risk of HQ as a carcinogen and understand mechanism of HQ-induced carcinogenesis in human epithelial cells.
The Journal of Korean Orthopaedic Ultrasound Society
/
v.4
no.2
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pp.101-110
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2011
To describe the background, mechanism, clinical results and complications of prolotheapy based on the literature review. Prolotherapy is a minimally invasive injection-based treatment of chronic musculoskeletal pain, including ligament and joint laxity. The mechanism of this injection-based technique is to initiate a local inflammatory response with resultant tissue healing. The used proliferants are classified by bio-mechanism to act in three different ways as osmotic, irritants, and chemotatics. The most commonly used proliferant is hyperosmolar (10~25%) dextrose to act by osmotic rupture of cells. High resolution ultrasound imaging of musculoskeletal structure provide a more accurate diagnosis. Also ultrasound-guided intervention provides a more high efficacy and low rate of complications. The most common complication is local pain at the injected site, that is self-limited and good responsive to anti-inflammatory agents. Other complications are rare. It is reported that prolotherapy appears safe when performed by an experienced clinician. Prolotherapy has grown in popularity and has received significant recent attention. However there are limited evidence-based data supporting the indication and efficacy of prolotherapy in the treatment of chronic musculoskeletal pain or soft tissue injuries. Future studies are necessary to determine whether prolotherapy can play an independent and definitive role in a treatment for chronic musculoskeletal pain.
A method to design a critical height of embankments is presented so as to mobilize fully soil arching in pile-supported embankments. The behavior of the load transfer of embankment weights on pile cap beams was investigated by a series of model tests performed on pile-supported embankments with relatively wide space between cap beams. The model tests explained that the behavior of the load transfer depended very much on the height of embankments, because soil arching could be mobilized in pile-supported embankments only under enough high embankments. The measured vertical loads on cap beams coincided with the predicted ones estimated by the theoretical equations, which have been presented in the previous studies on the basis of load transfer mechanisms according to either the punching shear failure mode during low filling stage or the soil arching failure mode during high filling stage. The mechanism of the load transfer was shifted beyond a critical height of embankment from the punching shear mechanism to the soil arching mechanism. Therefore, in order to mobilize soil arching in pile-supported embankments, the embankments should be designed at least higher than the critical height. A theoretical equation to estimate the critical height could be derived by equalizing the vertical loads estimated by the load transfer mechanisms on the basis of both the punching shear and the soil arching. The derived theoretical equation could predict very well the experimental critical height of embankment.
This study investigates the failure mechanism of RC beams strengthened with GFRP (glass fiber reinforced polymer) sheets. After analyzing failure mechanisms, the various methods to prevent the debonding failures, such as increasing bonded length of GFRP sheets, U-shape wrappings and epoxy shear keys are examined. The bonded length of GFRP sheets are calculated based on the assumed bond strengths of epoxy resin. The U-shape wrappings are either adopted at the end or center of the CFRP sheets bonded to the beam soft. The epoxy shear keys are embedded to the beam soft to provide sufficient bond strength. The end U-wrappings and the center U-wrappings are conventional, while epoxy shear keys are new details developed in this study. A total six half-scale RC beams have been constructed and tested to investigate the effectiveness of each methods to prevent debonding failure of GFRP sheets. From the experimental results, it was found that increasing bonded length or end U-wrappings do not prevent debonding failure. On the other hand, the beams with center U-wrappings and shear keys reached an ultimate state with their sufficient performance. The center U-wrappings tended to control debonding of the longitudinal GFRP sheets because the growth of the longitudinal cracks along the edges of the composites was delayed. In the case of shear keys, it was sufficient to prevent debonding and the beam was failed by GFRP sheets rupture.
The mechanism of load transfer by punching shear in pile-supported embankments is investigated. Based on the geometric configuration of the punching shear observed in sand fills on soft ground, a theoretical analysis is carried out to predict the embankment loads transferred on a cap beam according to punching shear developed in pile-supported embankments. The equation presented by the theoretical analysis was able to consider the effect of various factors affecting the vertical loads transferred on the cap beam. The reliability of the presented theoretical equation is investigated by comparing it with the results of a series of model tests. The model tests were performed on cap beams, which had two types of width; one is narrow width and the other is wide width. Sand filling was performed through seven steps. Two types of loading pattern were applied at each filling step; one is the long-term loading, in which sand fills at each filling step were kept for 24 hours, the other is the short-term loading, in which sand fills at each filling step were kept for 2 hours. The vertical loads measured in all model tests show good agreement with the ones predicted by the theoretical equation. Finally, the predicted vertical loads also show good agreement with the vertical loads measured in a well-instrumented pile-supported embankment in field, where cap beams were placed on too wide space.
Growth in the outsourcing market signals that firms of all sizes believe outsourcing will ultimately deliver many benefits and conveniences. But there are not many firms satisfied with the results of outsourcing. What is more, previous researches were fragmentary analyses focused on specific variables of outsourcing such as sourcing decisions, partnership rather than comprehensive analysis. Thus, they could not propose general systematic methodologies applicable to the real situation. To solve these problems, we developed an integrated theoretical framework that considered both contract with the hard side and trust with the soft side from a contingency viewpoint and tested this model using 143 data of Korean companies executing outsourcing. In addition, we examined how situational factors(outsourcing task complexity and outsourcing management competence) affects each path in the research model. The results of this study are as follows. First, it was proved the theory that trust is not a substitute for contract but its complement. Previous empirical studies on outsourcing success factors were focused on the establishment of successful partnership on the assumption that trust can replace contract in many situations. According to the results of our empirical analysis, however, contract and trust were in a mutually complementary relation with each other and their emphasis was different. Furthermore, different from previous researches, it was found effective to use trust as a supplementary tool and contract as a main means in outsourcing management strategy. Second, this study provided an integrated view that sees both contract and trust from a contingency viewpoint in theoretically reestablishing the relationship between contract and trust. Previous researches leaned to specific variables or theory-centered fragmentary analysis, but this study proposed a more practical and integrated research model and tested its effectiveness. Based on the results, with the model, decision makers are expected to scrutinize outsourcing situation more closely and to have a practical insight to the situation. Third, it was found that contract mechanism and trust building do not have a direct effect on outsourcing performance but relationship management intensity mediates the effect of contract mechanism and trust building. This is considered significantly meaningful to outsourcing partners who have believed that outsourcing would be successful if a contract is made properly or trust is built. Lastly, the path from trust building to relationship management intensity was moderated by informed buying, as the path coefficients from trust building to relationship management intensity varied by the degree of informed buying competence.
Geosynthetic-reinforced and Pile-supported (GRPS) embankment method is widely used to construct structures on soft ground due to restraining residual settlement and their rapid construction. However, effect of cyclic loading has not been established although some countries suggest design methods through many studies. In this paper, cyclic loading tests were conducted to analyze dynamic load transfer characteristics of pile-supported embankment reinforced with geosynthetics. A series of 3 case full scale model tests which were non-reinforced, one-layer-reinforced, two-layer reinforced with geosynthetics were performed on piled embankments. In these series of tests, the height of embankment and pile spacing were selected according to EBGEO (2010) standard in Germany. As a result of the vertical load parts on the pile and on the geosynthetic reinforcement measured separately, cyclic loads transferred by only arching effect decreased with strength geosynthetic-reinforced case. However, final loads on the pile showed no differences among the cases. These results conflict with previous studies that reinforcement with geosynthetics increases transfer load concentrated on piles. In addition, it is observed that the load transferred to pile decreases at the beginning of cycle number due to reduction of arching effected by cyclic loading. Based on these results, transferred mechanism for cyclic load on GRPS system has been presented.
Journal of the Korea institute for structural maintenance and inspection
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v.15
no.1
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pp.198-208
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2011
When a structure which has relatively low load constructs on soft clay, the bearing capacity of the ground will be improved by sand overlying clay. In this condition, verifying the bearing capacity is difficult from the P.B.T etcetera in the in-situ. So, it is needed to estimate precise bearing capacity in the design process. In this study, 2-dimensional chamber tests and FEM analyses are conducted to evaluate behavior of bearing capacity for shallow foundations on a sand overlying clay. Because depth ratio H/B and bearing capacity ratio $q_c/q_s$ are selected as main factors, height of a sand, undrained shear strength of a clay and width of a loading are designated as variables. Results from chamber tests are very similar with those of FEM analyses. And it shows that punching shear mechanism is more suitable than the equation of Okamura et al.(1998). To make continual application of load spread mechanism, the equivalent load spread angle is proposed for H/B and $q_c/q_s$. Also, the linear regression equation of critical depth ratio Hf is suggested for $q_c/q_s$.
A series of model tests were performed in this study to demonstrate the clogging mechanism created during the installation of a compaction pile to improve soft ground. The application of an air-jet to extrude sand or aggregates from a casing during the installation of a compaction pile imposes a remarkably high-pressure difference between the composite soil layers of clay and sand (or aggregates), resulting in severe clogging. Therefore, a one-dimensional testing system was developed to simulate composite soil layers consisting of clay and sand (or aggregates) and to apply a high-pressure differential at both boundaries, thus replicating the extrusion process used in compaction pile installation. Herein, the performance of two construction materials for compaction piles of crushed stone and grading-controlled aggregates was compared. A series of one-dimensional model tests were performed under multiple pressure settings, with clogging depth and permeability measured in each case. Results indicate that, blinding clogging mechanisms and blocking defined by previous studies were observed for crushed stone, and a new mechanism of "infiltration" was revealed and defined. Whereas, the controlled aggregates performed excellently against clogging because only blinding was observed.
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