• 한국학교보건학회지
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• 제29권2호
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• pp.81-89
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• 2016

Purpose: This study is to analyze influencing factors of smoking intention among nonsmoking middle school students with regard to smoking attitude, knowledge and social influence. Methods: Data were collected from non smoking students of 5 middle schools in D metropolitan city. The 1,892 enrolled subjects provided informed voluntary consent prior to completing a structural questionnaire covering smoking attitudes, knowledge, social influences and general characteristics. The data were analysed using SPSS/Win 21.0 program by -test and logistic regression analysis. Results: Among the nonsmoking students, 85.5% never had an intention to smoke. In relation to general characteristics, smoking intention was significantly associated with sex, school records, socioeconomic status, relationship with parents, smoking experience, and smokers around them. In relation to attitude, knowledge, and social influence, smoking intention was significantly associated with a lower attitude score, a lower knowledge score, and a lower social norm. In the logistic regression analysis, smoking intention was associated with a lower attitude score (2.99 times), a lower social norm (2.65 times), being male (2.35 times), low socioeconomic status (2.22 times). and having smoking experience (2.70 times). Conclusion: It is needed to develop promotional strategies that could provide adjusted systematic smoking prevention education for the preferred smoking group and afford smoking prevention programs considering subject characteristics to help young adolescents avoid access to smoking in their early age.

• 한국식생활문화학회지
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• 제28권2호
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• pp.125-134
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• 2013

This study investigated the effect of a health-related lifestyle on knowledge, attitude, control belief and behavior intention toward breast-feeding of male and female university students in order to develop a breast-feeding education program for students of childbearing age. The subjects were 445 university students (125 male and 325 female) residing in eight provinces in Korea. The overall percentage of subjects intending to breast-feed their baby was 80.7% (73.6% of males and 84.2% of females). Overall, 84.2% of the subjects had high concerns about their health status. Scores reflecting a positive attitude, knowledge, and control beliefs toward breast-feeding were significantly higher (p<0.05~p<0.001) in female students, students majoring in medicine, and higher grades. The students who scored high at attitude, knowledge, and control beliefs also had a significantly higher (p<0.001) intention to breast-feed. When we investigated the sub factors of attitudes toward breast-feeding, significantly more students taking nutrient supplements scored high for physiological factors (p<0.05) and health-related factors (p<0.01). Significantly more non-smoking and non-drinking students scored high for health-related factors (p<0.001) and physiological factors (p<0.001), respectively. The intention to breast-feed was found to be significantly higher (p<0.01) in students who did not smoke, but not with other health-related lifestyles. In summary, these results indicate that the majority of university students intend to breast-feed, with students having a positive attitude, higher knowledge, and stronger control beliefs having a higher intention to breast-feed. Although a student's health-related lifestyle affects their attitudes on the physiological and health-related aspects of breast-feeding, only smoking status had an observable connection on the intention to breast-feed. Thus, when developing breast-feeding education programs for students, we recommend efforts to enhance a favorable attitude, knowledge, and control beliefs toward breast-feeding.

• 사상체질의학회지
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• 제14권1호
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• pp.123-131
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• 2002

Glutathione S-transferase polymorphisms (GST) were examined in 98 cases with cerebrovascular disease (CVD) to test the hypothesis that GST polymorphisms confer a risk to an individual to develop CVD. Tobacco smoke is a major cause of both cancer and vascular disease. We therefore were stratified the subjects with CVD for smoking status, and then examined whether polymorphisms in this detoxification enzyme gene, GST, influence risk of CVD. Neither GSTM1 nor GSTT1 genotypes in the CVD group was significantly different from the control group (n=230), even in smokers. We attempted the combined analyses for GSTM1 and GSTT1 genotypes in CVD for smoking status. No significant association observed between the combined genotypes and CVD. We also classified the subjects and control group into four types according to Sasang Constitutional Medicine, Korean Traditional Oriental Medicine, and investigated the association among GST genotypes, CVD, and Sasang constitutional classification. Our observations do not confirm the effect of the GSTM1 and GSTT1 genotypes as a risk factor for CVD, even in smokers. Furthermore, we first attempted to evaluate the efficacy of Sasang Constitutional Medicine, and to find an association with CVD.

• 한국학교ㆍ지역보건교육학회지
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• 제7권
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• pp.33-49
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• 2006

Background & Objectives: This study was designed to examine relationships between smoking behavior and smoking attitudes among 6th-grade students in Korea in order to provide knowledge on school-based programs for preventing adolescent smoking behaviors. Methods: Questionnaires were administered to 464 students attending three public elementary schools in O city from June 13 to June 16, 2006. The total sample size is 458 (response rate = 98.7%). Data were statistically analyzed by frequency analysis, cross tabulation, and multiple regression. Results: First, smoking behavior was significantly influenced by the factors of gender, self-concept, family structure, sibling smoking, school achievement, relationship with teachers, satisfaction with school life, and smoking friends. Theprevalence of ever-smoking was 12.7% among 6th grade students in this study. Students were most likely to initiate smoking in the 5thgrade with curiosity and smoke at their own home. Second, students showed negative attitude toward smoking overall. From the detailed section, students respondednegatively about smoking in public places while they thought that adult smoking with moderate level was okay. Student who showed positive attitudes toward smoking in the present study were significantly related to the factors of self-concept, family environment, parental and sibling smoking status, school achievement, satisfaction with school life, and smoking friends. Third, Students who had tried cigarette smoking were likely to report less negative attitudes toward tobacco than non-smoking students. Fourth, this study found that smoking friends were the most significant predictor of positives smoking attitudes. Other factors significantlyassociated with smoking attitudes were gender, relationship with friends, self-concept, relationship with teachers, paternal smoking status. Conclusions: The study results suggest that smoking prevention programs focus on resisting peer influence and need to be community-incorporated and/or comprehensive from elementary to high school.

• 지역사회간호학회지
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• 제27권2호
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• pp.95-105
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• 2016

Purpose: This study examined the characteristics differences associated with 1-year continuous smoking abstinence in Korean young adult and middle-aged male workers. Methods: 'Korea National Health and Nutrition Examination Survey (KNHANES)' is an ongoing surveillance system that assesses the health and nutritional status of Koreans. For a secondary analysis of cross-sectional data from KNHANES VI-1, this study selected 683 Korean male workers as a subpopulation, who were young adult or middle-aged. The subpopulation was composed of success or failure group of 1-year continuous smoking abstinence. Binomial logistic regression analysis was performed. Results: Success group was more likely to be older, live in urban areas, rate their health status as excellent or good, and have ever been diagnosed with hypertension than failure group. Additionally, Success group was less likely to have used electronic cigarettes (e-cigarettes), drink more than once a month, and have been exposed to secondhand smoking in workplace within a week. Conclusion: Developing smoking cessation programs requires consideration of resources in rural areas, promoting self-efficacy, restricting e-cigarettes and drinking, and promoting a smoke-free workplace.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.2207-2212
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• 2012

Overexpression of DNA methyltransferase 1 (DNMT1) has been detected in many cancers. Tobacco exposure is known to induce genetic and epigenetic changes in the pathogenesis of malignancy. 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is an important carcinogen present in tobacco smoke; however the detailed molecular mechanism of how NNK induces esophageal carcinogenesis is still unclear. We found that DNMT1 was overexpressed in ESCC tissues compared with paired non-cancerous tissues, the overexpression being correlated with smoking status and low expression of $RAR{\beta}$. The latter could be upregulated by NNK treatment in Het-1A cells, and the increased DNMT1 expression level reflected promoter hypermethylation and downregulation of retinoic acid receptor ${\beta}$($RAR{\beta}$). RNA interference mediated knockdown of DNMT1 resulted in promoter demethylation and upregulation of $RAR{\beta}$ in KYSE30 and TE-1 cells. 3-(4,5-Dimethyl-thiazol-2yl)-2,5-diphenyltetrazolium bromide (MTT) and flow cytometric analysis demonstrated that NNK treatment in Het-1A cells could enhance cell proliferation and inhibit cell apoptosis in a dose-dependent manner. In conclusion, DNMT1 overexpression is correlated with smoking status and low expression of $RAR{\beta}$ in esophageal SCC patients. NNK could induce $RAR{\beta}$ promoter hypermethylation through upregulation of DNMT1 in esophageal squamous epithelial cells, finally leading to enhancement of cell proliferation and inhibition of apoptosis.

• 대한지역사회영양학회지
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• 제2권1호
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• pp.44-51
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• 1997

Secrum lipid and vitamin E levels were determined and smoking, alcohol drinking and exercise habits were asked in 357 healthy male subjects aged 49.4$\pm$6.7 years in Taegu. Average serum levels of total cholesterol, HDL-cholesterol and triglyceride(TG) were 189$\pm$43mg/이, 42$\pm$13mg/dl and 136$\pm$73mg/이, respectively. Serum level of lipid peroxide measured as thiobarbituric acid reactive substances(TBARS) of the subjects was 2.01$\pm$0.73MDA nmoles/ml and that of $\alpha$-tocopherol was 9.53$\pm$3.14ug/ml. The correlation coefficients between $\alpha$-tocopherol and serum lipids were 0.3631 for triglyceride, 0.2993 for cholesterol, and 0.3025 for total lipid. Heavy smokers who smoked more than 20 cigarettes a day had higher levels of TG and TBARS than those who smoke less. Alcohol drinkers had higher levels of TG and TBARS than nondrinkers. Vitamin E level(per ml serum)was significantly higher in the heavy smokers and drinkers, which was reflected by the higher level of serum lipid. When the level of $\alpha$-tocopherol was expressed as $\alpha$-tocopherol/triglyceride, it was negatively correlated with serum TBARS level and was lower in the heavy smokers than in the moderate smokers. It is concluded that vitamin E level as $\alpha$-tocopherol/triglyceride would be better compared to $\alpha$-tocopherol/total cholesterol or $\alpha$-tocopherol/total lipid for the evaluation of vitamin E status in Korean men.

• Advances in Traditional Medicine
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• 제4권2호
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• pp.112-119
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• 2004

Glutathione S-transferase polymorphisms (GST) were examined in 98 cases with cerebrovascular disease (CVD) to test the hypothesis that GST polymorphisms confer a risk to an individual to develop CVD. Tobacco smoke is a major cause of both cancer and vascular disease. We therefore were stratified the subjects with CVD for smoking status, and then examined whether polymorphisms in this detoxification enzyme gene, GST, influence risk of CVD. Neither GSTM1 nor GSTT1 genotypes in the CVD group was significantly different from the control group (n=230), even in smokers. We attempted the combined analyses for GSTM1 and GSTT1 genotypes in CVD for smoking status. No significant association observed between the combined genotypes and CVD. We also classified the subjects and control group into four types according to Sasang Constitutional Medicine, Korean Traditional Oriental Medicine, and investigated the association among GST genotypes, CVD, and Sasang constitutional classification. Our observations do not confirm the effect of the GSTM1 and GSTT1 genotypes as a risk factor for CVD, even in smokers. Furthermore, we first attempted to evaluate the efficacy of Sasang Constitutional Medicine, and to find an association with CVD.

• 한국안전학회지
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• 제24권4호
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• pp.28-33
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• 2009

This study examined the mounting status of cigar lighter receptacles for vehicles and analyzed the tracking phenomenon that occurs when foreign material entered a cigar lighter receptacle to obtain data for the analysis of accident investigation. Regardless of the vehicle's output, cigar lighter receptacles are mounted in a vehicle horizontally, vertically, or at tilting or inclined angle. The tilting type cigar lighter receptacle is much easier to use but current leakage resulting from foreign materials (coffee, beverages, water, etc.) falling into the cigar lighter receptacle may cause a fire to start. This study used a vehicle battery (DC 12V) as a power supply for the tracking test and configured its circuit in the same way as that of an electrical device in a vehicle. The tracking phenomenon that occurred in the standby mode of the vehicle exhibited a fine flame and an irregular occurrence of smoke. While this tracking phenomenon was occurring, the leakage current and the reaching distance of the flame were measured to be approximately 930mA and $20{\sim}50cm$, respectively. It is thought that the resultant flame may ignite toluene, dust, cigarettes, etc. It was observed that as the tracking progressed, the internal metal socket melted and a hole was created, the surface of which was also severely carbonized. In addition, the electrical resistance of the carbonized conductive path was measured to be approximately $30{\Omega}$. It is thought that this much resistance may cause local heating when leakage current flows and could ignite any nearby flammable material.

• Child Health Nursing Research
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• 제15권4호
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• pp.367-374
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• 2009

Purpose: The purpose of this study was to identify the relationship of knowledge and attitude to temptation toward cigarette smoking in adolescents. Methods: A survey was conducted using a 52-item questionnaire in 2 high school settings. Descriptive statistics, t-tests, ANOVA, post hoc analysis and Pearson correlation coefficients were used with SPSS WIN version 14.0 to analyze the data. Results: There were significant differences in attitude toward smoking and smoking temptation depending on gender, academic performance, religion, current smoking status, parental responses toward smoking, initiation of smoking, and the number of friends who smoke (p<.001). The level of smoking knowledge was not related to any of general characteristics as well as attitude toward smoking and smoking temptation. However, negative attitude toward smoking was moderately correlated with reduced smoking temptation (r=-.608, p<.001). Conclusion: Adolescents' attitude toward smoking and coping ability against smoking temptation were influenced by various factors related to smoking behavior and social situations, rather than by the level of smoking knowledge. In order to develop an effective smoking prevention and cessation program for adolescents, various strategies to change attitudes toward smoking should be included.