• BMB Reports
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• 제49권6호
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• pp.303-304
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• 2016

Myoblast fusion is important for skeletal muscle formation. Even though the knowledge of myoblast fusion mechanism has accumulated over the years, the initial signal of fusion is yet to be elucidated. Our study reveals the novel function of a phosphatidylserine (PS) receptor, stabilin-2 (Stab2), in the modulation of myoblast fusion, through the recognition of PS exposed on myoblasts. During differentiation of myoblasts, Stab2 expression is higher than other PS receptors and is controlled by calcineurin/NFAT signaling on myoblasts. The forced expression of Stab2 results in an increase in myoblast fusion; genetic ablation of Stab2 in mice causes a reduction in muscle size, as a result of impaired myoblast fusion. After muscle injury, muscle regeneration is impaired in Stab2-deficient mice, resulting in small myofibers with fewer nuclei, which is due to reduction of fusion rather than defection of myoblast differentiation. The fusion-promoting role of Stab2 is dependent on its PS-binding motif, and the blocking of PS-Stab2 binding impairs cell-cell fusion on myoblasts. Given our previous finding that Stab2 recognizes PS exposed on apoptotic cells for sensing as an "eat-me" signal, we propose that PS-Stab2 binding is required for sensing of a "fuse-me" signal as the initial signal of myoblast fusion.

• 대한기계학회논문집A
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• 제21권7호
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• pp.1013-1020
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• 1997

Among various gyroscopes, the vibrating gyroscope has advantages such as compact size, mass-productivity and low cost. However this kind of gyroscope usually suffer from low linearity and low signal to noise ratio. Therefore, it is necessary to study on vibrating gyroscope to improve performance. In this paper, triangular cross section si selected in consideration for several points. The existing designs of exciting and sensing have some problems such that small signal size and low linearity. This paper proposes new design of exciting and sensing which is named one period exciting and the other period sensing. This design improves signal size, but it cannot improve linearity. This is because above two designs are the same open-loop type. So, another new design is proposed, which is named rebalancing, is applied to one period exciting and the other period sensing. This design are closed-loop type. It feedbacks the output signal. According to control theory, it can improve linearity. The circuits of each design are realized and used to calibration test. Calibration results show that new design of rebalancing improves linearity and signal size.

• 한국정보통신학회논문지
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• 제5권7호
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• pp.1287-1294
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• 2001

심전도는 파형의 크기가 수 ㎷정도로 아주 작은 생체신호로서, 계측할 때 발생되는 잡음으로 인하여 해석하는데 어려움을 준다[1]. 깨끗한 파형을 얻기 위해서는 심전도 신호에 포함되어 있는 전원 잡음, 기저선 변동, 근 잡음을 제거해야 된다. 심전계에서 심전도 신호를 기록하는데 있어서 가장 큰 문제를 야기하는 부분이 기저선 변동인데 전극을 부착한 부위의 근육수축과 호흡의 리듬에 따라서 발생하게 된다. 그러한 기저선은 상하로 심하게 불규칙한 변동을 하면서 흔들리게 되어 심전도 신호를 진단하는데 어려움이 있으므로 기저선 변동을 제거하는 부분이 매우 중요하다. 본 연구에서는 실시간으로 신호처리 할 수 있는 디지털 필터를 구현함으로써 기저선 변동을 제거하는 시스템을 설계하여 환자의 심장질환을 분석하는데 응용할 수 있도록 하였다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1999년도 추계학술대회 논문집 학회본부 B
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• pp.742-744
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• 1999

In this paper, a new precharge type PFD for fast locking time of PLL is suggested. It is realized by inserting NMOS transistor and inverter into the precharge part of PFD for isolating the reset of the Up signal from the feedback signal. The new precharge type PFD generates the Up signal while the feedback signal is fixed at a high level. Therefore the new PFD output is increased than the conventional precharge type PFD output. As a result of the increased PFD output, fast locking of PLLs is achieved. Additionally, with control the falling time of the inverter, the dead-zone is reduced and the jitter characteristics are improved. The whole characteristics of PFD and PLL are simulated by using HSPICE. Simulation results show that the dead-zone is 20ps and the locking time of PLL using the new PFD is 38ns at the 350MHz frequency of referecne signal. This value is quite small compared with conventional PFD.

• Journal of the Optical Society of Korea
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• 제18권6호
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• pp.657-662
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• 2014

We demonstrate a simulation of a parallel hybrid fiber amplifier in the C+L-band with a gain controlling technique. A variable optical coupler is used to control the input signal power for both EDFA and RFA branches. The gain spectra of the C+L-band are flattened by optimizing the coupling ratio of the input signal power. In order to enhance the pump conversion efficiency, the EDFA branch was pumped by the residual Raman pump power. A gain bandwidth of 60 nm from 1530 nm to 1590 nm is obtained with large input signal power less than -5 dBm. The gain variation is about 1.06 dB at a small input signal power of -30 dBm, and it is reduced to 0.77 dB at the large input signal power of -5 dBm. The experimental results show close agreement with the simulation results.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제14권6호
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• pp.2634-2648
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• 2020

In this paper, an adaptive sparse singular value decomposition (ASSVD) algorithm is proposed to estimate the signal matrix when only one data matrix is observed and there is high dimensional white noise, in which we assume that the signal matrix is low-rank and has sparse singular vectors, i.e. it is a simultaneously low-rank and sparse matrix. It is a structured matrix since the non-zero entries are confined on some small blocks. The proposed algorithm estimates the singular values and vectors separable by exploring the structure of singular vectors, in which the recent developments in Random Matrix Theory known as anisotropic Marchenko-Pastur law are used. And then we prove that when the signal is strong in the sense that the signal to noise ratio is above some threshold, our estimator is consistent and outperforms over many state-of-the-art algorithms. Moreover, our estimator is adaptive to the data set and does not require the variance of the noise to be known or estimated. Numerical simulations indicate that ASSVD still works well when the signal matrix is not very sparse.

• 한국인터넷방송통신학회논문지
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• 제15권2호
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• pp.99-104
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• 2015

본 논문에서는 통신 채널에서 발생되는 부호간 간섭 영향을 최소화시키기 위한 MMA 적응 등화 알고리즘의 성능을 개선시키기 위한 RMMA (Region based Multiple Modulus Algorithm) 알고리즘을 제안한다. RMMA 알고리즘에서는 적응을 위한 오차 신호를 얻기 위하여 등화기 출력 constellation을 4개의 영역으로 분할한 후 각 영역별로 4-QAM 신호로 매핑하므로서 nonconstant modulus 신호를 constant modulus 신호로의 변환 효과를 얻으며, 이로 인하여 더욱 적은 오차 신호를 얻을 수 있게 된다. 논문에서는 제안 알고리즘인 RMMA의 적응 등화 성능을 평가하기 위하여 기존 방식인 MMA와 비교하였다. 컴퓨터 시뮬레이션 결과 잔류 isi와 MD에서 수렴 속도와 잔류양에서 개선되었으며, 특히 SER에서 기존 MMA보다 월등함을 알 수 있었다.

• Journal of Electrical Engineering and Technology
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• 제9권1호
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• pp.334-343
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• 2014

In this paper, we suggest a method to improve the fusion of an accelerometer and gyro sensor by using a Kalman filter to produce a more high-quality respiration signal to supplement the weakness of using a single accelerometer. To evaluate our proposed algorithm's performance, we developed a chest belt-type module. We performed experiments consisting of aerobic exercise and muscular exercises with 10 subjects. We compared the derived respiration signal from the accelerometer with that from our algorithm using the standard respiration signal from the piezoelectric sensor in the time and frequency domains during the aerobic and muscular exercises. We also analyzed the time delay to verify the synchronization between the output and standard signals. We confirmed that our algorithm improved the respiratory rate's detection accuracy by 4.6% and 9.54% for the treadmill and leg press, respectively, which are dynamic. We also confirmed a small time delay of about 0.638 s on average. We determined that real-time monitoring of the respiration signal is possible. In conclusion, our suggested algorithm can acquire a more high-quality respiration signal in a dynamic exercise environment away from a limited static environment to provide safer and more effective exercises and improve exercise sustainability.

• 정보저장시스템학회:학술대회논문집
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• 정보저장시스템학회 2005년도 추계학술대회 논문집
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• pp.190-194
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• 2005

There is a great demand of micro-actuators for mobile information devices such as SFF optical drives and mobile camera phones. However, conventional magnetic coils of electromagnetic motors are a major obstacle for miniaturization because of their complicated structures and large power consumption. In this paper, a linear ultrasonic motor to actuate focusing lens of mobile devices is proposed. The new actuator uses a ring type bimorph piezoelectric material, and $d_{31}$ mode is adopted for applying linear motion. The interaction between inertia force and friction force makes linear motion by high-frequency saw signal input. The saw signal gives steady forces on the one direction by asymmetric inclination property of the signal itself on time domain. A commercial FEM (ANSYS) was used in this investigation for simulating structural analysis, identification of dynamic property, such as resultant displacement and coupled analysis with piezoelectric material. To evaluate the performance of the new design, a prototype was manufactured and experiments were carried out. Experimental results show the actuator motion of 1.52 mm/s at 10 kHz input signal in 5 V.

• 정보저장시스템학회논문집
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• 제2권4호
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• pp.251-256
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• 2006

There is a great demand of micro-actuators for mobile information devices such as SFF optical drives and mobile phone cameras. However, the magnetic coils used in conventional electromagnetic motors are a major obstacle for the miniaturization because of their complicated structures and large power consumption. In this paper, a linear ultrasonic motor to actuate focusing lens of mobile devices is proposed. The new actuator uses a ring type bimorph piezoelectric material, and $d_{31}$ mode is adopted for applying linear motion. The interaction between inertia force and friction force makes linear motion by high-frequency saw signal input. The saw signal gives steady forces on the one direction by asymmetric inclination property of the signal itself on time domain. A commercial FEM(ANSYS) was used in this investigation for simulating structural analysis, identification of dynamic property, such as resultant displacement and coupled analysis with piezoelectric material. To evaluate the performance of the new design, a prototype was manufactured and experiments were carried out. Experimental results show the actuator motion of 5.4 mm/s at 10V saw signal of 41 kHz.