• 대한수의학회지
• /
• 제56권4호
• /
• pp.223-227
• /
• 2016

This study evaluated the levels of cardiac biomarkers in dogs with either pulmonic stenosis or aortic stenosis and the correlation between biomarkers and the severity of stenosis assessed by the echocardiography. To achieve this study goal, 38 dogs (10 healthy control dogs, 15 dogs with pulmonic stenosis and 13 dogs with aortic stenosis) were examined. The jet velocity and pressure gradient in this study population were measured by echocardiographic estimation, after which the study group was subdivided by the severity of stenosis. The plasma cardiac troponin I (cTnI) and N-terminal pro-brain natriuretic peptide (NT-proBNP) were measured in this study group. The median concentrations of cTnI and NT-proBNP of the disease group were significantly higher than those of the control group, and these increased gradually as stenosis worsened. The severity of stenosis and the concentrations of cTnI and NT-porBNP were also found to be significantly correlated. Finally, the plasma cTnI and NT-proBNP tests were found to beneficial for differentiating clinical patients, predicting the progression of disease, and monitoring the outcome of interventional therapy for stenosis.

• Journal of Chest Surgery
• /
• 제3권2호
• /
• pp.91-106
• /
• 1970

Two groups of left pulmonary-subclavian artery anastomosis were done in 26 adult mongorel dogs. For the first group. the distal end of the subclnvian artery was nnastomosed to the side of the left pulmonary artery, and for the second group, the subclavian end wns anastomosed to the proximal end of the left lower lobe pulmonary artery. Among them, 6 died of bleeding or anesthetic failure during the day of operation, 10 survived 1 to 106 days and the other 10 were sacrificed at various interval. To investigate the relationship between hemodynamic stress and temporal evolution of the pulmonary vascular lesions. the pulmona try and femoral artery pressures, arteriogram and pathohistological specimens were obtained. The following results were obtained. 1. The postoperative pulmonary artery pressures were within normal limits except 2 dogs in the first group, but in nil 12 dogs of the second group, they were in moderate to maked pulmonary hypertension level. 2 After subclavian pulmonary anastomosis, both groups dogs showed increased femond artery pulse pressure. 3. The pulmonary vascular changes were more severe and appeared earlier in the second group dogs compared with the first group.4. The earliest vascular changes appeared in the media of the small muscular arteries and arterioles. 5. Various vascular chaDges were produced in 2 or 3 months. Thereafter, the changes were stationary. 6. Among the first group, two long-term servivors (No. 705 & 713) which had normal pulmonary artery pressure under the anesthesia, also showed various vascular changes as other pulmonary hypertensive dogs. 7. In the early stage medial hypertrophy. interruptio~l of elastic lamellae were found in the small muscular arteries and arterioles, which were followed by intimal proliferation and thrombosis. These findings may suggest some evidences of trauma to the vessels. 8. Pulmonary arteriograms showed irregularity of the intima of the large and medium sized arteries, abrupt ending of some of the small arteries and narrowing of the anastomosis.

• 한국임상수의학회지
• /
• 제32권3호
• /
• pp.231-234
• /
• 2015

본 연구에서는 소형견종에서 전 십자인대 단열과 동적 안정화를 이용한 치료법에서 사용되는 경골 고평부각(the tibial plateau angle)을 측정하였다. 경골 고평부각을 측정하기 위해 성장이 끝난 소형견종 32마리의 사체의 양측 뒷다리를 이용하였다. 성별, 각 양측다리(왼쪽, 오른쪽), 그리고 견종별로 구분하여 경골 고평부각을 평가하였다. 전체 소형견종의 평균 경골 고평부각은 $26.13^{\circ}{\pm}2.33^{\circ}$이었다. 왼쪽 다리와 오른쪽 다리는 각각 $26.00^{\circ}{\pm}2.23^{\circ}$와 $26.26{\pm}2.45$로 측정되었고 성별에 따른 측정에서는 암컷은 $26^{\circ}.22{\pm}2.80^{\circ}$로 수컷은 $26.01^{\circ}{\pm}1.57^{\circ}$로 평가 되었다. 견종별로는 말티즈는 $26.06^{\circ}{\pm}2.96^{\circ}$로 푸들은 $25.21^{\circ}{\pm}1.38^{\circ}$로 시추는 $26.65^{\circ}{\pm}2.96^{\circ}$로 요크셔 테리어는 $26.27^{\circ}{\pm}1.61^{\circ}$로 측정되었다. 모른 측정치의 확률적 유의적 차이는 없었다. 본 연구에서 측정된 소형견의 경골 고평부각은 전 십자인대의 병적 상태평가와 수술 과정에서 중요한 정보를 제공할 수 있다고 사료된다.

• 한국임상수의학회지
• /
• 제31권6호
• /
• pp.483-489
• /
• 2014

본 연구는 소형견에서 전 십자인대 단열에서 경골 고평부 평탄 골절단술로 치료된 증례의 예후와 수술적 기법에 대해 보고하고자 한다. 5 kg 미만의 7 마리의 성견에서 편측 전 십자인대 단열에서의 경골 고평부 평탄 골절단술을 이용한 증례를 본 연구에서 이용하였다. 임상적 관찰, 파행 지수, 관절의 운동 범위, 대퇴 둘래 길이를 측정하고 수술 후 부작용에 대해 기록하였다. 모든 환자에서 수술 후 1주에 파행 지수 1을 8주 이후에는 파행 지수 0를 보여 주었다. 수술한 다리의 펴짐각은 다른 쪽 정상 다리와 비교하여 4주에 98.11%로 8주에 99.07%로 12주에 98.73%로 측정되었고 굽힘각은 4주에 98.07%로 8주에 95.88%로 12주에 96.35%로 측정되었다. 수술 후 대퇴 둘레 길이는 다른쪽 정상 다리와 비교하여 4주에 92.95%를 8주에 93.68%를 12주에 95.44%를 보여 주었다. 우리가 수술 한 결과는 이전에 보고된 대형견에서 경골 고평부 평탄 골절단술의 이용 결과들과 비교하여 나쁘지 않은 결과를 보여 주었다. 본 증례를 바탕으로 대형견에서와 같이 소형견에서도 경골 고평부 평탄 골절단술이 전 십자인대 단열에서 성공적으로 사용될 수 있다고 사료된다.

• 대한수의학회지
• /
• 제63권4호
• /
• pp.34.1-34.9
• /
• 2023

Dogs exhibit patterns of health issues that vary by life stage. An understanding of disease incidence with respect to breed and age/life stage could be an important component of canine health management and welfare. This study aimed to describe the age-specific disease incidence of 3 small dog breeds that attended veterinary clinics in the Republic of Korea, based on data from electronic veterinary medical records (EVMRs). A total of 40,785 EVMRs from Maltese (n = 21,355), Miniature Poodle (n = 11,658) and Shih Tzu dogs (n = 7,772) were analyzed. Common health problems in 3 small dog breeds were 'diseases of the skin' and 'diseases of the ear,' respectively. Among dogs aged ≤ 3 years, 'preventive medicine' was the most common cause cited for veterinary clinic visits. Among dogs aged 4 to 8 years, the most frequent health problems were 'diseases of the skin.' Among dogs aged 9 to 13 years, 'heart diseases,' 'kidney diseases,' 'mammary gland tumor,' and 'neoplasia (unspecified)' were considerably more frequent, compared to the rates in dogs ≤3 years. Among dogs aged ≥ 14 years, 'heart diseases' and 'sneezing/cough' were the main health problems. In all breeds, the frequencies of 'diseases of circulatory system,' 'diseases of respiratory system,' 'diseases of the nervous system,' 'endocrine' and 'neoplasia' increased rapidly with aging. This surveillance could inform strategies for disease screening tests and management based on life stage in these dog breeds and enable more effective health management.

• 한국임상수의학회지
• /
• 제20권4호
• /
• pp.443-448
• /
• 2003

본 연구는 전십자인대가 단열된 개의 슬관절액에서 tartrate-resistant acid phosphatase (TRAP) 와 cathepsin K의 변화를 알아봄으로서 십자인대에 관련된 질병 또는 십자인대 치료 실패에 따른 퇴행성관절염의의 조기 진단 및 치료에 관한 정보를 얻기 위하여 실시하였다. 실험동물로는 전방십자인대가 단열된 30두의 개와 정상 성견 8 두 그리고 어린 정상 개 9두를 사용하였다. 슬관절액 내의 TRAP 과 Cathepsin K의 변화를 확인하기 위하여 조직화학 염색과 면역조직화학염색을 실시하였다. 조직학적인 검사 결과 정상견에서는 TRAP과 Cathepsin K 세포들은 찾아보기 힘들었으나 전방십자인대가 단열된 개에 있어서는 TRAP 과 Cathepsin K 그리고 chondroid metaplasia가 중심부분에서 증가되고 있음을 관찰하였다. 이러한 결과로 보아 TRAP과 Cathepsin K 세포들은 전방십자인대가 단열 또는 단열 후 회복되는 과정에서 상호 보조적으로 관여하며 세포외 방출과 관계가 있는 것으로 생각된다.

• 대한수의학회지
• /
• 제57권2호
• /
• pp.113-116
• /
• 2017

The aim of this study was to examine normal bronchi in dogs by using virtual bronchoscopy (VB) and to evaluate the utility of VB in clinical practice. The bronchi of six dogs without tracheobronchial disease were visualized by VB. Airways from the tracheal bifurcation to the lobar bronchi were well visualized in all dogs. Segmental and subsegmental bronchi were also well identified, but the degree and number of those varied with dog size. The mean numbers of segmental and subsegmental bronchi identified in the six dogs were 41.83 and 50.17, respectively, whereas, the mean numbers in medium- and large-sized dogs were 55.00 and 82.67, respectively, and in small-sized dogs, the means were 28.67 and 17.67, respectively. Although there were size-dependent differences in VB visualization of the bronchi, it was possible to identify peripheral airways to the subsegmental bronchi level, which can rarely be accomplished via conventional bronchoscopy. VB is the noninvasive method that can be used to examine bronchial anatomy, and our results suggest that VB can be useful for evaluating bronchi, including segmental and subsegmental ones that cannot be examined routinely by conventional bronchoscopy. Thus, VB has potential as an alternative to conventional bronchoscopy in the examination of bronchi in dogs.

• 한국임상수의학회지
• /
• 제36권2호
• /
• pp.93-97
• /
• 2019

Healing of 48 cases of radial fractures in small breed dogs treated with acrylic pin external fixation was evaluated retrospectively to investigate the factors affecting the healing of radial fractures. The mean age of the subjects was 15.02 months, the mean body weight was 3.48 kg, and the mean maximum length of the radius (MLR) was 90.77 mm. External skeletal fixation frames type 1a, 2a, and 3 were used; among them type 2a was used most frequently (75%). The mean time to clinical union (TCU) was 67.17 days, and the success rate was 95.8%. Age, bodyweight, MLR, and occurrence of complications increased TCU significantly. Among complications, pin loosening, swelling of the operated forelimb tissue for more than 2 weeks, and coexistence of two or more complications increased TCU significantly (p < 0.05). There was no relationship between location of the fracture and TCU. The results of this study may be useful to predict the prognosis of radial fractures in small dogs.

• 한국임상수의학회지
• /
• 제35권5호
• /
• pp.200-205
• /
• 2018

This retrospective study is designed to compare the clinical results of tibial tuberosity transposition (TTT) and anti-rotation suture (ARS) treatments for medial patellar luxation (MPL). Medical records of 133 dogs were reviewed that had undergone surgical correction of MPL between January 2013 and May 2017. MPL correction was performed on 182 stifles, with TTT and ARS being performed on 101 stifles and 81 stifles. The common dog breeds receiving surgical treatment for MPL were Maltese, Pomeranian, Chihuahua and Poodle. Mean age of dogs with MPL was 32.6 months, and their mean body weight was 4.26 kg. Seventy dogs (52.6%) were male and 63 (47.4%) were female. Of the 182 stifles with MPL, grade II, III and IV were 18.7%, 72.0% and 9.3%. Total complications after TTT and ARS were recorded in 16.8% and 29.6%. Major complications after TTT and ARS were recorded in 5.9% and 12.3%, minor complications after TTT and ARS were recorded in 10.9% and 17.3%. The risk of complication and reluxation rate after TTT were significantly lower than that for ARS (p < 0.05). However, the rate of reluxation among dogs treated by ARS (1.2%) for grade II MPL was significantly lower than that for dogs treated by ARS (8.6%) for grade III MPL (p < 0.05). The TTT group had a shorter recovery period after surgical intervention than that in the ARS group (p < 0.001). In conclusion, TTT had a significantly lower incidence of complication and a shorter recovery period than ARS. However, ARS for grade II MPL appears to be a good surgical option for reducing the rate of reluxation after surgery. These results of this study could be used to provide therapeutic guidelines for surgical MPL correction in small-breed dogs.

• 한국임상수의학회지
• /
• 제30권1호
• /
• pp.36-40
• /
• 2013

Caval syndrome은 감염된 다수의 심장사상충이 우심방, 우심실을 포함한 우심계와 대정맥으로 이동하여 삼첨판의 움직임을 물리적으로 방해하고 폐동맥으로 가는 혈류의 장애를 유발하여 생명을 위협하는 질환이다. 이 질환의 치료를 위해 외과적인 사상충의 제거가 필요하다. 본 증례는 modified extraction brushes를 이용한 새로운 방법의 심장사상충 제거 방법에 대한 보고이다. 본 연구에서 새롭게 만들어진 사상충 제거 카테터를 사용하여 caval syndrome에 감염된 두 마리의 개를 성공적으로 치료하였다. 비록 새로운 시술법의 적용이 단지 두 증례에 불과하지만, 본 시술법은 심장 사상충 치료를 위한 외과적 제거방법 중 하나로 선택할 수 있다.