• Asian-Australasian Journal of Animal Sciences
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• 제23권6호
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• pp.777-785
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• 2010

The effect of two doses of different sources of zinc, inorganic (zinc oxide) or chelated (zinc glutamate chelate), on morphology and turn-over of the small intestine was assessed in early-weaned pigs orally challenged with enterotoxigenic E. coli K88 (ETEC). Sixty pigs weaned at 21 days were assigned to one of the following 5 diets: control (C); C+Zinc oxide (ZnO), either a 200 or a 2,500 mg Zn/kg dose; or C+zinc chelate with glutamic acid (Glu-Zn), either a 200 or a 2,500 mg Zn/kg dose. On d 2, the pigs were orally inoculated with 1.5 ml of a $10^{10}$ CFU/ml E. coli K88ac O148 suspension. Zinc supplements did not improve the performance of the pigs, but on d 5 faecal excretion of ETEC was reduced, and this was mainly due to high zinc doses (p<0.05). The villous height in the duodenum was improved by the zinc supplements (p<0.01) whatever the source and the level, whereas no effect was seen in the other two tracts of small intestine. The diet did not affect apoptosis and mitosis counts, while ETEC-susceptible pigs had more mitotic cells in the villi than non-susceptible pigs, particularly in the jejunum (p<0.01). The duodenum had fewer mitotic cells in the villi (p<0.05) and in the crypts (p<0.01) and more apoptotic cells in the villi. High dietary doses of ZnO or Zn-Glutamate improve villous height of the duodenum, but not of the jejunum and the ileum, and do not affect the epithelial proliferative activity and apoptotic index of intestinal mucosa of early-weaned pigs orally challenged with ETEC.

• 한국임상수의학회지
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• 제26권2호
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• pp.160-165
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• 2009

4개월령 수컷 박서 개(체중: 9 Kg)가 심잡음과 운동불내성을 주요 증상으로 내원하였다. 진단검사를 통해 환자는 대동맥 판막하 협착에 이환된 것을 확인할 수 있었다. 협착된 부위의 압력구배는 120 mmHg(와류의 속도: 5.4 m/s)이상이었으며, 환자는 풍선 확장술을 통해 임상증상을 개선하였다. 환자는 시술 후 주기적으로 모니터링 하였으며 다른 임상증상은 관찰되지 않았다. 이는 우리나라에서 대동맥 판막하 협착증에 이환된 환자에게 풍선 확장술을 통해 임상증상을 경감시킨 최초의 증례이다.

• 대한수의학회지
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• 제56권4호
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• pp.223-227
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• 2016

This study evaluated the levels of cardiac biomarkers in dogs with either pulmonic stenosis or aortic stenosis and the correlation between biomarkers and the severity of stenosis assessed by the echocardiography. To achieve this study goal, 38 dogs (10 healthy control dogs, 15 dogs with pulmonic stenosis and 13 dogs with aortic stenosis) were examined. The jet velocity and pressure gradient in this study population were measured by echocardiographic estimation, after which the study group was subdivided by the severity of stenosis. The plasma cardiac troponin I (cTnI) and N-terminal pro-brain natriuretic peptide (NT-proBNP) were measured in this study group. The median concentrations of cTnI and NT-proBNP of the disease group were significantly higher than those of the control group, and these increased gradually as stenosis worsened. The severity of stenosis and the concentrations of cTnI and NT-porBNP were also found to be significantly correlated. Finally, the plasma cTnI and NT-proBNP tests were found to beneficial for differentiating clinical patients, predicting the progression of disease, and monitoring the outcome of interventional therapy for stenosis.

• 한국임상수의학회지
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• 제29권5호
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• pp.404-407
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• 2012

3년령 암컷 잡종개(체중 5.3 kg)가 실신, 운동불내성, 의기소침, 기면 등의 증상으로 강원대학교 동물병원에 내원하였다. 진단검사상 적혈구증가증이 관찰되고, 흉부방사선 검사상 심한 우심종대 패턴이 관찰되었으며, 심초음파상우-좌 단락의 심방중격 결손증, 심한 폐동맥 협착증(~5 m/s of peak velocity)과 우심실 비대소견이 관찰되었다. 환자는 진단영상학적 소견을 근거로 팔로삼징(trilogy of Fallot)으로 진단되었다. 환자의 임상증상을 안정화시키기 위해 diltiazem과 enalapril을 투여하였고 일주일에 한번씩 정맥사혈을 실시하고 있다. 본 증례는 국내에서 최초로 보고되는 팔로삼징의 증례이다.

• 한국임상수의학회지
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• 제27권5호
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• pp.569-572
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• 2010

간헐적인 기절과 운동 불내성의 주요증상을 호소하는 4살 령의 중성화된 암컷 페키니즈 개 (체중 3.6 kg)가 내원하였다. 신체검사상 지속적인 맥박 결손을 가진 아주 불규칙한 심박동(irregularly irregular heart rhythm)이 나타났다. 12 유도 표면 심전도에서는 동방결절 기능 부전군을 의미하는 간헐적인 방실 접합부 이탈박동과 함께 특이적인 동정지가 나타났다. 본 환자에 대한 심장 박동수 반응형의 양극성 심장 박동조절기(VVIR type)를 이용한 영구적 경정맥형 심박 조율시술은 우심실 내에서 실시되었다. 심장 박동기 장착 이후, 환자의 임상증상은 눈에 띠게 호전되었다. 시술이후 아직까지 기절의 증상은 더 이상 나타나지 않고 있다.

• 한국임상수의학회지
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• 제31권6호
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• pp.507-510
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• 2014

8개월령 암컷 포메라니안 개가 심잡음과 심비대를 주호소로 내원하였다. 검사결과 좌-우단락 동맥관 개존증과 중등도의 심부전 (ISACHC II) 으로 진단되었다. 잔존 동맥관은 우측 대퇴동맥을 통한 $5mm{\times}3loops$ 코일 색전술을 통해 성공적으로 치료되었다. 2개월 후 환축은 현저한 저혈압과 심한 설사, 흉수가 차는 증상으로 다시 내원하였다. 검사 결과 심각한 폐성고혈압과 삼첨판 역류가 발견되었다. Sildenafil (3 mg/kg, PO, TID) 을 투여함으로써 임상증상은 조절되었으나, 코일빠짐과 보호자의 부적절한 투약으로 인해 환축은 폐사하였다. 부검 결과 폐성고혈압의 원인은 비정상적인 위치로 빠진 색전 코일에 의한 것으로 밝혀졌다. 토이 품종에서 PDA의 치료를 위해 색전 코일이 널리 사용되고 있지만, 장착된 코일이 빠질 위험을 줄이기 위해서는 PDA의 크기와 형태에 대한 한층 더 세심한 평가가 필요하다.

• Animal Bioscience
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• 제35권12호
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• pp.1904-1910
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• 2022

Objective: This study aimed to investigate the effects of corticotropin-releasing factor (CRF) on the feed intake of broiler chickens and explore its influencing mechanism. Methods: The study included two trials. In trial 1, 32 male broiler chickens (Arbor Acres, Gallus gallus domesticus) were given ventricle buried tubes, and they were allowed to recover for 3 days. At 8:00 AM, intracerebroventricular (ICV) injection with CRF or normal saline was performed in 10-day-old broiler chickens, which were divided into the 5, 10, and 20 ㎍ and control (normal saline) groups according to the dose of CRF injection. In trial 2, chickens were divided into the 10 ㎍ and control group (physiological saline) to repeat trial 1. Results: Results of trial 1 showed that the cumulative amount of feed intake in the 10 or 20 ㎍ groups was considerably lower than that of the control group after ICV injection with CRF. The lowest amount of feed intake was obtained with the addition of 10 ㎍ of CRF. In trial 2, the expression of ghrelin in the hypothalamus injected with 10 ㎍ of CRF increased significantly, but the expression of ghrelin in various sections of the small intestine considerably decreased. The expression of CRF receptor subtypes 1 (CRFR1) in the hypothalamus and some parts of the small intestine remarkably increased, and the expression of CRF receptor subtypes 2 (CRFR2) increased only in the duodenum, whereas the expression of growth hormone secretagogue receptor (GHSR-1α) in the jejunum and ileum increased considerably after ICV injection of 10 ㎍ of CRF. Conclusion: The CRF at 10 ㎍ increased ghrelin expression in the hypothalamus and CRFR1 expression in the small intestine, and this phenomenon was related to the suppressed feed intake of broiler chickens.

• Journal of Veterinary Science
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• 제25권2호
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• pp.25.1-25.12
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• 2024

Background: Surgical excision is the treatment of choice for feline intracranial meningioma. Objectives: To report clinical findings, complications, and outcomes following surgery for feline intracranial meningioma. Methods: Medical records (01/2000-01/2017) of cats that underwent surgical excision of an intracranial meningioma at our institution were reviewed. Patient data included signalment, clinical signs, surgical technique, complications, histopathologic diagnosis, survival time, and owners' answers to a satisfaction questionnaire. Survival was assessed using the Kaplan-Meier method and log-rank test. Results: Twenty-six cats were included in this study. The exact cause of death was known in 17 cases and was not related to meningioma in 9/17 cases. Overall median survival time was 881 days (95% confidence interval 518; 1248). The age of the cat did not influence survival (p = 0.94) or the occurrence of complications (p = 0.051). Complications occurred in 13/24 cats, including dramatic complications in 4/24 cats. Most complications appeared in the first 24 hours post-surgery (12/13). Males had more postoperative complications (p = 0.042), including more seizures (p = 0.016). Cats with cranioplasty had fewer complications (p = 0.021). Clinical recurrence was confirmed in 3 out of 17 cats. Recurrence-free survival time was 826 days. Most owners (12/14) were satisfied with the outcome. Conclusions: Surgical treatment of intracranial meningioma in cats was associated with a long median survival time but also with a high rate of minor and major postoperative complications, including early postoperative seizures. Cranioplasty may reduce complications. Age at the time of surgery had no effect on outcomes.

• Asian-Australasian Journal of Animal Sciences
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• 제16권10호
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• pp.1406-1410
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• 2003

The studies were based on the RAPD fingerprinting for the species identification of animals. The genomic DNA samples of ostriches, Taiwan local chickens, Aboracres broilers, Leghorn chickens, quails, doves, emus, Beltville small white turkeys, pheasants, Chinese geese, mule ducks, Holstein cattle and Landrace pigs were amplified with random primers by RAPD-PCR for fingerprinting. The results showed that the varied band patterns of DNA fingerprints were generated from templates depending on the kinds of primers or animal species. The same primer applied to the same breed, all of the main bands are similar, but which were different among species. In order to try to identify the species from the mixture of meat by RAPD fingerprinting, the meat of ostrich and cattle was mixed in different ratios for this study. The results showed that it could be easily and precisely distinguished according to the band distribution of RAPD patterns.

• Asian-Australasian Journal of Animal Sciences
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• 제22권6호
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• pp.900-905
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• 2009

We analyzed succession of the bacterial communities during composting of animal manure in three individual facilities. Polymerase chain reaction (PCR) and denaturing gradient gel electrophoresis (DGGE) targeting for the bacterial 16S rRNA gene were used to clarify the changes of bacterial community throughout each composting process. Our study revealed that the bacterial community structures differed during the composting process. The bacterial community in composting of facility A showed little change throughout the process. In the compost sample from facility B, its community had a small shift as the temperature increased. In compost from facility C, the temperature dynamically changed; it was shown that various bacterial communities appeared and disappeared as follows: in the initial phase, the members of phylum Bacteroidetes dominated; in the thermophilic phase, some bacteria belonging to phylum Firmicutes increased; towards the end, the community structure consisted of three phyla, Bacteroidetes, Firmicutes, and Proteobacteria. This study provides some information about the bacterial community actually present in field-scale composting with animal manure.