• The Korean Journal of Physiology
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• v.14 no.1
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• pp.25-30
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• 1980

It has been well known that beta-adrenoceptor is responsible for the renin release stimulatory and alpha-adrenoceptor may be inhibitory. It has been observed accidently that alpha-adrenergic agonist can inhibit renin release by just changing the medium temperature in Vitro experiment in this laboratory. A series of experiments were performed to clarify this interesting phenomena in Vitro experiment. Rat renal slices were incubated in PSS medium under gas phase at $37^{\circ}C$. The following results were observed. 1) Isoproterenol and norepinephrine resulted in renin release stimulatory in dose-dependent by the concentrations of $10^{-9}$ to $10^{-5}\;M/L$ at $37^{\circ}C$. 2) Norepinephrine resulted in renin release inhibitory in dose dependent by the concentrations of $10^{-7}$ to $10^{-5}\;M/L$, and almost no effect by isoproterenol $10^{-6}\;M/L$ at $20^{\circ}C$. 3) Phenoxybenzamine pretreatment at $37^{\circ}C$ accentuated isoproterenol stimulatory effect at $37^{\circ}C$. 4) Phenoxybenzamine pretreatment at $20^{\circ}C$ attenuated isoproterenol stimulatory effect at $37^{\circ}C$. These data suggest that the renal adrenoceptor(s) related to renin release maybe a single entity, and can be interconverted different forms in certain conditions.

• Journal of Korea Multimedia Society
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• v.18 no.10
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• pp.1189-1196
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• 2015

In this paper, we proposed automatic extraction of brain tumor using morphological operation and statistical tumors size in MR images. Neurosurgery have used gamma-knife therapy by MR images. However, the gamma-knife plan systems needs the brain tumor regions, because gamma-ray should intensively radiate to the brain tumor except for normal cells. Therefore, gamma-knife plan systems spend too much time on designating the tumor regions. In order to reduce the time of designation of tumors, we progress the automatical extraction of tumors using proposed method. The proposed method consist of two steps. First, the information of skull at MRI slices remove using statistical tumors size. Second, the ROI is extracted by tumor feature and average of tumors size. The detection of tumor is progressed using proposed and threshold method. Moreover, in order to compare the effeminacy of proposed method, we compared snap-shot and results of proposed method.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.3 no.4
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• pp.280-284
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• 2002

This paper presents computer simulations of the stacking and transferring system for the fast freeform fabrication system. The stacking and transferring system is essential for the fast freeform fabrication system and its stable motion is very important for consistent stacking of the cut slices. The stacking and transferring system can be modeled as a pneumatic system. The system consists of air compressor, the control valve, and the cylinder. The governing parameters have been changed and the simulation results are shown to predict the time response of the system. The results show some parameters should be correctly tuned to obtain stable system response.

• Journal of Biomedical Engineering Research
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• v.27 no.6
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• pp.409-417
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• 2006

Research on neural circuit is a difficult area due to complexity and inaccessibility. Due to recent developments, the research using multi-electrode array of cells or tissues has become an important research area. However, there are some difficulties to decode the submerged meaning from huge and complex neural data. Moreover, it needs a harmonic collaboration between informatics and bioscience. In this paper, we have developed a custom-designed signal processing technique for multi-electrode array measured neural responses induced by electrical stimuli to the hippocampal tissue slices of the rat brain. The raw data from hippocampal slice using the multi-electrode array system were saved in a computer. Then we estimated characteristic points in each channel and calculated the total activity. To estimate the points, we used the Polynomial Fitting Approximation Method. Using the calculated total activity, we could provide the histogram or pseudo-image matrix to help interpretation of results.

• The Korean Journal of Physiology and Pharmacology
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• v.1 no.5
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• pp.477-484
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• 1997

Intracellular recordings of oscillatory firing (bursting activity) were obtained from Purkinje cells (PCs) in rat cerebellar slices. Apamin inhibited post-burst hyperpolarizations (PBHs) progressively and finally terminated oscillatory firing activity of PCs. Apamin did not affect the amplitude or duration of the after-hyperpolarization (AHP) between spikes within the burst. In the voltage clamp mode, apamin shifted the whole-cell, quasi-steady state I/V relationship in an inward direction and abolished the zero slope resistance (ZSR) region by blocking outward current. Nickel ($Ni^{2+}$) terminated oscillatory activity and also abolished the ZSR region. However, $Ni^{2+}$ did not have progressive blocking action on the post-burst hyperpolarization before it blocked oscillatory activity. $Ni^{2+}$ blocked an inward current at potentials positive to approximately -65 mV, which was responsible for the ZSR region and outward current at more negative potentials. These data indicated that oscillatory activity of PCs is sustained by a balance between a slow $Ni^{2+}$-sensitive inward current and an apamin-sensitive outward current in the region of ZSR of the whole-cell I/V curve.

• The Korean Journal of Applied Statistics
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• v.18 no.2
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• pp.381-393
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• 2005

As a promising technique for dimension reduction in regression analysis, Sliced Inverse Regression (SIR) and an associated chi-square test for dimensionality were introduced by Li (1991). However, Li's test needs assumption of Normality for predictors and found to be heavily dependent on the number of slices. We will provide a unified asymptotic test for determining the dimensionality of the SIR model which is based on the probabilistic principal component analysis and free of normality assumption on predictors. Illustrative results with simulated and real examples will also be provided.

• Journal of the Semiconductor & Display Technology
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• v.5 no.2 s.15
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• pp.19-25
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• 2006

This paper focuses on lossy medical image compression methods for medical images that operate on three-dimensional(3-D) irreversible integer wavelet transform. We offer an application of unbalanced tree structure algorithm to medical images, using a 3-D unbalanced wavelet decomposition and a 3-D unbalanced spatial dependence tree. The wavelet decomposition is accomplished with integer wavelet filters implemented with the lifting method. We have tested our encoder on volumetric medical images using different integer filters and coding unit sizes. The coding unit sizes of 16 slices save considerable dynamic memory(RAM) and coding delay from full sequence coding units used in previous works. If we allow the formation of trees of different lengths, then we can accomodate more transaxial scales than three. The encoder and decoder can then keep track of the length of the tree in which each pixel resides through the sequence of decompositions. Results show that, even with these small coding units, our algorithm with certain filters performs as well and better in lossy coding than previous coding systems using 3-D integer unbalanced wavelet transforms on volumetric medical images.

• ETRI Journal
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• v.29 no.6
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• pp.736-744
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• 2007

We propose a fast macroblock (MB) mode prediction and decision algorithm based on temporal correlation for P-slices in the H.264/AVC video standard. There are eight block types for temporal decorrelation, including SKIP mode based on rate-distortion (RD) optimization. This scheme gives rise to exhaustive computations (search) in the coding procedure. To overcome this problem, a thresholding method for fast inter mode decision using a MB tracking scheme to find the most correlated block and RD cost of the correlated block is suggested for early stop of the inter mode determination. We propose a two-step inter mode candidate selection method using statistical analysis. In the first step, a mode is selected based on the mode information of the co-located MB from the previous frame. Then, an adaptive thresholding scheme is applied using the RD cost of the most correlated MB. Secondly, additional candidate modes are considered to determine the best mode of the initial candidate modes that does not satisfy the designed thresholding rule. Comparative analysis shows that a speed-up factor of up to 70.59% is obtained when compared with the full mode search method with a negligible bit increment and a minimal loss of image quality.

• 제어로봇시스템학회:학술대회논문집
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• 2005.06a
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• pp.2164-2169
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• 2005

SFFS(Solid Freeform Fabrication System) can quickly makes models and prototype parts from 3D computer-aided design (CAD) data. Three dimensional printing(3DP) is a kind of the solid freeform fabrication. The 3DP process slices the modeling data into the 50-200um along to z axis. And we pile the powder and make the manufactures. A manufacture is made by the SFFS has the precision of the 50um. Therefore the x-y table of SFFS to move a printhead must be the system that has a high speed and accuracy. So we proposed the SMCSPO algorithm for SFFS. The major contribution is the design of a robust observer for estimating the state and the perturbation of the timing belt system, which is combined with a robust controller. The control performance of the proposed algorithm is compared with PD control by the simulation and the experiment. The control algorithm of the SFFS is presented in the office environment. The system between control system and printhead for the SFFS is also integrated

• The korean journal of orthodontics
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• v.42 no.3
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• pp.110-117
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• 2012

Objective: In this study, we measured the cortical bone thickness in the mandibular buccal and lingual areas using computed tomography in order to evaluate the suitability of these areas for application of temporary anchorage devices (TADs) and to suggest a clinical guide for TADs. Methods: The buccal and lingual cortical bone thickness was measured in 15 men and 15 women. Bone thickness was measured 4 mm apical to the interdental cementoenamel junction between the mandibular canine and the 2nd molar using the transaxial slices in computed tomography images. Results: The cortical bone in the mandibular buccal and lingual areas was thicker in men than in women. In men, the mandibular lingual cortical bone was thicker than the buccal cortical bone, except between the 1st and 2nd molars on both sides. In women, the mandibular lingual cortical bone was thicker in all regions when compared to the buccal cortical bone. The mandibular buccal cortical bone thickness increased from the canine to the molars. The mandibular lingual cortical bone was thickest between the 1st and 2nd premolars, followed by the areas between the canine and 1st premolar, between the 2nd premolar and 1st molar, and between the 1st molar and 2nd molar. Conclusions: There is sufficient cortical bone for TAD applications in the mandibular buccal and lingual areas. This provides the basis and guidelines for the clinical use of TADs in the mandibular buccal and lingual areas.