• Nutrition Research and Practice
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• 제12권3호
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• pp.208-214
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• 2018

BACKGROUND/OBJECTIVES: The aim of this study was to evaluate the biological and sleep-promoting effects of combined ${\gamma}$-aminobutyric acid (GABA) and 5-hydroxytryptophan (5-HTP) using caffeine-induced sleepless fruit flies, ICR mice, and Sprague-Dawley rats. MATERIALS/METHODS: Video-tracking analysis was applied to investigate behavioral changes of Drosophila melanogaster. Pentobarbital-induced sleep test and electroencephalogram (EEG) patterns were used for analysis of sleep latency, duration, and quantity and quality of sleep in vertebrate models. RESULTS: Administration of combined GABA/5-HTP could significantly reverse the caffeine induced total distance of flies (P < 0.001). Also, individually administered and combined GABA/5-HTP significantly increased the total sleeping time in the caffeine-induced sleepless ICR mice (P < 0.001). In the caffeine-induced sleepless SD-rats, combined GABA/5-HTP showed significant differences in sleep quality between individual amino acid administrations (P < 0.05). CONCLUSIONS: Taken together, we identified inhibitory effects of combined GABA/5-HTP in locomotor activity, sleep quantity and quality in caffeine-induced sleepless models, indicating that combined GABA/5-HTP may be effective in patients with insomnia by providing sufficient sleep.

• 문화기술의 융합
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• 제8권5호
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• pp.663-668
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• 2022

수면장애 경험자의 수가 지속적으로 증가하면서 수면의 질 개선에 대한 사용자의 니즈가 증가하고, 이를 바탕으로 슬립테크 시장이 꾸준한 성장세를 보인다. 본 연구에서는 수면위생 기반 맞춤형 서비스의 필요성을 바탕으로 현대인의 수면장애 극복에 도움될 시스템 관련 연구 및 기술 고찰 후 애플리케이션을 설계하여 제안하고자 한다. 본 시스템은 스마트폰 내장 센서를 통해 수집한 사용자의 수면 데이터를 분석하여 수면 패턴을 계산하고, 협업 필터링을 통해 사용자 개인에게 맞춤형 수면위생 기반 솔루션을 제공하며, IoT 기기의 자동 제어로 수면에 적합한 환경을 제공한다. 이러한 수면 데이터의 활용 방식은 사용자의 수면 습관 개선을 비롯해 슬립테크 시장으로 확장하여 수면 장애로 고통 받는 현대인의 삶의 질 향상에 기여할 것으로 기대된다.

• Clinical and Experimental Pediatrics
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• 제46권4호
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• pp.363-369
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• 2003

목 적 : 본 연구는 저신장 소아 중 성장호르몬 약물자극검사에서는 정상반응을 나타낸 특발성 저신장 소아들을 대상으로 야간의 수면 양상과 성장호르몬 분비가 정상 신장의 아동과 차이가 있는지 알아보고자 하였다. 방 법 : 성장호르몬 약물자극검사에서 정상반응을 보인 신장이 3 백분위수 이하인 특발성 저신장 아동 12명과 정상 신장 아동 9명을 대상으로 30분 간격으로 야간수면 동안의 자발적 성장호르몬 분비를 측정하고 동시에 polysomnography로 수면양상을 비교 분석하였다. 결 과 : 1) 야간 수면 중 분비된 성장호르몬의 평균농도는 저신장 아동군이 정상 아동군에 비해 유의하게 낮았으며($2.8{\pm}0.2 ng/mL$ vs $4.7{\pm}0.6 ng/mL$), 특히 수면개시 후 서파 수면과 동반되는 성장호르몬 최대 분비치가 저신장 아동군이 낮았다. 2) 수면 중 성장호르몬 농도가 5 ng/mL 이상인 성장호르몬 분비 최대치의 횟수는 각각 $4.1{\pm}0.5$회, $5.8{\pm}0.6$회로 저신장군이 유의하게 적었다. 3) 전체 수면 시간에 대한 서파 수면 시간의 백분율도 저신장 아동군이 정상 아동군에 비해 감소되어 있었다($16.4{\pm}1.3%$ vs $20.8{\pm}1.2%$). 결 론 : 야간 수면 동안의 자발적인 성장호르몬 분비 검사가 약물자극검사에서 정상반응을 보이는 특발성 저신장 아동의 추가적인 진단에 도움을 줄 수 있으며 이들 저신장 아동에서 보이는 야간 성장호르몬 분비 감소는 수면구조의 차이와 일부 관련이 있는 것으로 생각된다.

• 대한한방소아과학회지
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• 제27권3호
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• pp.65-73
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• 2013

The subjects were composed of 308 children who visited the department of pediatrics, ${\bigcirc}{\bigcirc}$ korean medicine hospital from January 2010 to May 2013. Results 1. Among 308 patients, there were 188 boys and 120 girls; their ratio was 1.57:1. The age distribution showed that 38.3% were in the age less than 1 years, 38.0% in 1 years, 7.8% in 2 years, 5.2% in 3 years, 3.3% in 4~5 years, 4.5% in 6~10 years, 2.9% in 19~21 years. 2. It was found that 36.7% of the sleep disorder was caused without motivation, 17.2% caused by negligent accidents, 13.9% by traffic accidents, 10.4% by the unfamiliar environment, 8.1% by separation from parents, 7.5% after suffering disease, and 6.2% by irritating sound. 3. The sleep onset insomnia accounts for 17.2% of sleep disorder, sleep maintenance insomnia for 67.5%, poor sleep quality 24.4%, and daytime sleep disorder takes 19.8%. The ratio of sleep onset insomnia in adolescence comprises larger proportion (44.4%) than it of any other age groups. 4. The symptoms complicated with sleep disorder are the respiratory infection which takes 25.3%, being easily startled 18.2%, anorexia 14.6%, soft stools frequency 13.0%, greenish stools 10.7%, and skin rash 10.7%. Conclusions The causes of sleep disorders, changes of sleeping patterns, and complicated diseases show diversity in children and adolescence. Further study of sleep disorders in children and adolescence should be progressed as well.

• 기본간호학회지
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• 제18권4호
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• pp.488-496
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• 2011

Purpose: To determine the type and degree of effect that a hot footbath has on sleep quality and fatigue level in older Korean adults. Methods: A non-equivalent control group quasi-experimental design was used. Fifty participants from a long-term care facility in Kwangju, South Korea, were randomly selected and assigned to two groups: experimental group (27 participants) and control group (23 participants). The participants in the experimental group received hot footbaths in a temperature-controlled water tub of $42^{\circ}C$. They soaked their feet up to 20cm above the ankles for 30 minutes before going to bed for 3 nights. Actigraphy was used to measure their sleep patterns. The data were analyzed using the SAS program. Results: After the intervention, the total sleep satisfaction rate of the participants increased, while sleep latency and fatigue decreased significantly in the experimental group compared to the control group. Conclusion: The study results suggest that hot footbaths are beneficial for older Korean adults in enhancing sleep quality as well as reducing fatigue. Therefore, hot footbaths are recommended as a nursing intervention to improve sleep quality and to reduce fatigue in older Korean adults.

• 기본간호학회지
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• 제23권1호
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• pp.21-31
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• 2016

Purpose: This study is a qualitative research to identify new nurses' adaptation experience to sleep changes. Method: Grounded theory methodology was utilized. Participants were 10 new nurses from one university hospital. The information was collected and analyzed using the grounded theory of Corbin and Strauss'(2008). Results: Through constant comparative analysis, central phenomenon was identified as 'Shaky daily life due to the sleep change'. A core category emerged as 'In the shaky daily life, go grab my position', Causal conditions were 'Heaviness in shift work', 'Not released after getting off work', and 'Body and mind are exhausted'. Context were 'An environment that does not tolerate mistakes' and 'Clogged breathing due to worries'. Intervening factors were 'Support of colleagues', 'Recovery volition in restoration of altered relationships due to sleep'. Action/Interaction Strategies were 'To strive for a good sleep', 'Require a reasonable duty schedule' and 'Find a breakthrough'. Consequences were 'Become the master of shaky daily life' and 'Accepting the life of a nurse'. Conclusion: New nurses experience sleep patterns changes from the hospital shift system. but throughout the process of adaptation, came to accept sleep disorder as part of the life of a nurse.

• 수면정신생리
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• 제8권1호
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• pp.5-10
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• 2001

The prevalence of insomnia and the degree of impairment due to insomnia is greater than in the of young. The cause for insomnia in the elderly are various factors among the elderly is known to be high including medical, psychiatric, drug issues, circadian rhythm changes, sleep disorders, and psychosocial. So the careful evaluation to find the cause of insomnia is needed for the eldery. Treatment options for insomnia include behavior modification and pharmacotherapy. Outcome data from previous studies indicate that behavioral approaches produce reliable and durable therapeutic benefits, as evidenced by improved sleep efficiency and continuity and enhanced satisfaction with sleep patterns. Treatment methods such as stimulus control and sleep restriction, which target maladaptive sleep habits, are especially beneficial for older insomniacs, whereas relaxation-based interventions aimed at decreasing arousal, produce more limited effects. Cognitive and educational interventions are instrumental in altering age-related dysfunctional beliefs and attitudes about sleep. The choice of hypnotics is based on matching the nature of the insomnia to the hypnotic agent. The ideal agent has rapid onset, duration of action that lasts through the night but no residual daytime effects, and no adverse effects. The key for the healthcare professional is finding the appropriate treatment or treatment combination, including behavioral modification and pharmacotherapy. When hypnotics are indicated, the most appropriate short-acting agent should be considered.

• 한국통신학회논문지
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• 제32권3A호
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• pp.221-229
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• 2007

본 논문에서는 IEEE 802.16e 기반 Wireless Metropolitan Area Network (WMAN) 이동 단말의 전력 소모 최소화를 위한 최적 휴면 기법 (sleep mode)을 제안한다. 802.16e 표준에 정의된 sleep 모드 단말은 항상 현재 접속 중인 기지국 (BS)과 상태 정보를 유지해야 하므로, 단말이 기지국을 이동할 때마다 새로운 기지국과 sleep 상태를 재 협상해야 한다. 따라서 sleep 모드는 단말의 이동성이 클수록 헨드오버 (handover)에 의해 불필요한 전력 소모가 증가한다. 이에 따라 본 논문에서는 단말의 이동성은 사용자의 호 사용 패턴과 무관하다는 것에 착안하여 헨드오버에 따른 불필요한 베터리 소모를 제거할 수 있는 최적 휴면 기법을 제안한다. 본 논문에서는 제안 기법의 성능을 전력 소모량과 착신 호의 초기 응답 시간 측면에서 수학적으로 분석하였고 모의 실험을 통해 제안한 분석 모델을 검증하였다. 또한 기존 sleep 모드와 제안 기법의 성능을 모의 실험을 통해 비교하여 제안 기법은 기존 sleep 모드에 비해 수용 가능할 만큼의 초기 응답 시간을 증가시키지만 전력 소모량을 보다 많이 줄일 수 있다는 것을 검증하였다.

• 기본간호학회지
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• 제10권2호
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• pp.214-222
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• 2003

Purpose: This study was done to investigate sleep patterns and utilization of the charcoal eyepatch In high school students through a survey research. Method: The participants in this study were 80 students in a high school in Seoul. The period of data collection was from July 1, 2002 to 15, 2002. The research instruments used in this study were the measures of sleep and SPSSWIN 10.0 Program was used for data analysis. Result: The students went to bed after 12 p.m., but many of them easily fell asleep within 5 minutes. They woke up quite early at around 4 to 6 o'clock in the morning but remained in bed 1 hour. Satisfaction with their sleep was the response for 38.8% of the students. While 77% napped, they generally did so in the afternoon and 38.8% napped for half an hour. As for quality of sleep, 2.5% of the students could not sleep deeply, and 21.7% woke frequently during sleep. Their sleep environments were calm and comfortable, and they turned off the light when sleeping. The utilization of the charcoal eyepatch was effective for sleep, fatigue and powerlessness in high school students. Conclusion: Utilization of the charcoal eyepatch was effective for sleep in high school students and while the utilization of charcoal is recommended in life, the effect of charcoal must be testified through research.

• Child Health Nursing Research
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• 제16권4호
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• pp.239-248
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• 2010

Purpose: This study was done to evaluate effects of a mother-fetus interaction promotion program on maternal and infant sleep/activity regulation, and examine the correlation between maternal and infant sleep/activity. Methods: Thirty-four mother-infant dyads were recruited from an OB-GY clinic with postpartum care center, and assigned to the intervention group (17) or control group (17). Data were collected from January 18 to August 5 2005. A programmed education focused on mother-fetus interaction was provided to the intervention group in the 3rd trimester. Maternal sleep/activity record was completed at 32-36 weeks gestation and infant sleep/activity record was completed for one month after birth. Results: During the 3rd trimester, there were no significant differences in maternal sleep/activity between the groups, except for frequency of mothers' night awakening and urination at night. There were no significant differences in infant sleep, but significant difference was found in feeding times between the groups. Correlation of maternal sleep in the 3rd trimester and infant waking times was significant. Conclusion: The results of this study indicate that maternal sleep/activity during pregnancy influences infant sleep/activity at 3-4 weeks, and that nursing interventions to regulate maternal sleep/activity provided to primiparas can be beneficial to the regularity of infant sleep/activity patterns.