• 한국안전학회지
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• 제15권4호
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• pp.56-61
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• 2000

The precise and reliable loss model for induction motor and converter system is very important in order to predict the efficiency performance of variable speed drives. This paper proposes an accurate loss model of induction motor and converter system. The motor losses, such as stator and rotor copper loss, core loss and stray loss, are considered for fundamental and harmonic frequencies. Also considered are the skin effect on rotor resistance, temperature effect on bath stator and rotor resistance, magnetizing inductance saturation, and friction and windage loss. All the above features are incorporated in a synchronous frame dynamic d-q equivalent circuit. The converter system, consisting of a diode rectifier and PWM transistor inverter, is modeled accurately for conduction and switching losses. Validity of the models, in both steady state and transient conditions, is verified by simulations.

• 한국산업보건학회지
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• 제16권4호
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• pp.398-412
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• 2006

The purpose of this study is to investigate the relationship between the acceleration of vibration by the powered hand tools used in the shipbuilding industry, and to develop the prospective prevalence model for the hand-arm vibration syndrome among the shipbuilding workers.The acceleration levels and frequencies of six types of grinder were measured using the ISO5349 method along with the time of exposure to the vibration from the powered hand tools. Medical examination for 114 workers were performed using the cold provocation test. Comparisons were made between the estimated prevalence of hand-arm vibration syndrome from ISO5349 and the observed values from the medical examinations. By multiple regression, we developed the prospective prevalence model of hand-arm vibration syndrome produced by the hand tools used in the shipbuilding industry. 4 hour-energy-equivalent frequency-weighted accelerations were $6.23m/s^2$ in the grinding job done after welding, and $13.39m/s^2$ in the grinding job done before painting. The mean exposure time while holding powered hand tools was 4.64 hours. Prevalence rates of Raynaud's Phenomenon were 12.04% in the grinding after soldering, and 42.9% in the grinding before painting measured using the ISO5349 method. After exposure to vibration for 10.79 years, about a half of the workers in the grinding after welding could developed Raynaud's Phenomenon. For the workers in the grinding before painting, the latency was 5.02 years. The ISO equation for dose response relationship was not significantly correlated with observed recovery rates of finger skin temperatures, blood flows and amplitudes of nerve conduction velocities. A multiple regression model for dose-response relationship was proposed from the results. Recovery rate of the skin temperatures = -0.668+ 0.337 ${\times}$ 4 hour energy equivalent frequency-weighted accelerations + 0.767 ${\times}$ duration of vibration exposure(years) The validity was proved by multiple regression analysis after correlation transformation and regression results based on model-building data and validation data.

• Journal of Microbiology and Biotechnology
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• 제7권4호
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• pp.267-271
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• 1997

We developed a dermal equivalent (DE) which was engineered using human dermal fibroblasts and a matrix of collagen gel. The in vitro construction of the DE was accomplished by casting a porcine collagen type I solution plus concentrated medium with isolated and cultured fibroblasts. These constructs were attached to culture dishes or left floating in culture medium. Contraction of attached gels results in decreased gel thickness without a change in gel diameter, and contraction of floating gels results in decreased gel thickness and diameter. After contraction, there was no increase in cell number in floating gels, but cells in attached gels began to increase after about 4 days of the lag phase in cell growth curve. At this lag phase, addition of fibroblast growth factor (FGF) at a concentration of $0.1{\mu}$/ml promoted cell proliferation in the attached collagen gels, but no effect in floating gels. These results indicate that the method of contraction had an influence on the extracellular matrix (ECM) organization, and this influenced not only cell growth but also fibroblast responsiveness to FGF. This suggests that attached collagen gel is more suitable as a dermal equivalent than the floating gel. And the final contracted area of attached gel is much larger than that of the floating gel since floating gel is contracted in all directions but attached gel is contracted only vertically.

• 대한화장품학회지
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• 제46권1호
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• pp.73-80
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• 2020

심리적 스트레스는 피부의 생리적 상태에 영향을 미치고 다양한 피부 질환을 일으킬 수 있다. 스트레스 호르몬인 코티솔은 섬유질, 케라틴세포, 멜라노사이트와 같은 다양한 피부세포에 의해 분비된다. 밀착연접(tight junction, TJ) 은 포유류 피부의 과립증에서 장벽을 형성하는 세포 접합부위이다. TJ은 다른 피부 장벽기능에도 영향을 미칠 수 있으며 화학, 미생물 또는 면역학적 피부장벽에게 영향을 받는다. 스트레스로 인한 피부 장벽 손상에 관한 보고는 있지만 사람피부에서 코티솔이 TJ을 조절한다는 보고는 없다. 스트레스 호르몬 코티솔이 TJ을 조절하는 기능을 확인하기 위해 각질형성세포에 코티솔을 처리하였다. 코티솔은 TJ 구성 성분의 유전자 발현과 구조를 조절하여 피부 장벽 기능을 손상시켰다. 또한 코티솔은 인공피부 모델에서 과립층 형성을 억제하였다. 이러한 실험결과를 통해 스트레스 호르몬 코티솔이 TJ를 조절함으로써 피부 장벽 기능에 손상을 일으키는 것을 확인할 수 있었다.

• 전기전자학회논문지
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• 제23권4호
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• pp.1122-1127
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• 2019

본 연구에서는 인체의 생체임피던스는 임상 및 생물학적 조직의 병적 및 생리적 상태를 모니터링 하여 많은 정보를 획득 가능하다. 생체임피던측정용 4 전극법시스템은 2개의 전극은 생체의 전위차를 측정하였고, 다른 두 전극은 전류를 흘러주는 전극으로 사용하였다. 새롭게 개발된 건식 Gold 전극은 1 Hz에서 50 kHz 까지 임피던스를 측정하였으며, 재현성 있는 결과를 얻었다. 건식전극의 임피던스 측정값을 검증하기 위해서 생체전극피부등가회로를 이용하여 피팅을 실시하였고 모델링을 통해서 실효성을 증명하였다. 고정 전극형태는 측정 시 부착되는 전극의 위치가 일정하므로 안정적인 측정값을 얻을 수 있어서 오류를 최소화할 수 있다.

• 대한전기학회논문지:전기기기및에너지변환시스템부문B
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• 제53권5호
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• pp.351-357
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• 2004

In this paper, we present an analytical method that provides fast and efficient evaluation of the conversion efficiency for switching power supplies. In the proposed method, the conduction losses are evaluated by calculating the effective values of the ideal current waveform first and incorporating them into an exact equivalent circuit model of the switching power supply that includes all the parasitic resistances of the circuit components. While the winding losses and core losses are accurately accounted for the magnetic components, the skin and proximity effects are assumed to be negligible in order to simplify the analysis. The validity and accuracy of the proposed method are verified with experiments on a prototype active-clamped forward converter with synchronous rectification. An excellent correlation between the experiments and theories are obtained for the input voltages of 36-75 V with 4-6 MOSFETs employed for the synchronous rectification.

• 한국진공학회지
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• 제8권3B호
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• pp.368-375
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• 1999

The Maxwell equation and the transformer equivalent-circuit model are applied to a radio frequency planar inductively coupled plasma. The spatial distribution of the vector potential, the magnetic field, and the electric field are obtained analytically. As a result, the plasma current, the mutual inductance between the coil and the plasma, and the self inductance of plasma are found to increase with increasing skin depth. The spatial distribution of absorbed power has maximum where the antenna coil exists, and has a similar profile to that of the induced electric field. The power transfer efficiency is found to increase with increasing gas pressure before a saturation around p+ 20mTorr, while it shows an increase with the plasma density before a slight decrease around a density of $5\times10^{11}/\textrm{cm}^3$.

• JSTS:Journal of Semiconductor Technology and Science
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• 제2권1호
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• pp.1-6
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• 2002

A new closed-form expressions to calculate frequency-dependent distributed inductance and the associated distributed series resistance of single interconnect on a lossy silicon substrate (CMOS technology) are presented. The proposed analytic model for series impedance is based on a self-consistent field method and the vector magnetic potential equation. It is shown that the calculated frequency-dependent distributed inductance and the associated resistance are in good agreement with the results obtained from rigorous full wave solutions and CAD-oriented equivalent-circuit modeling approach.

• The Korean Journal of Physiology and Pharmacology
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• 제25권1호
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• pp.15-26
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• 2021

Peptides are short chain of amino acids linked by peptide bonds. They are widely used as effective and biocompatible active ingredients in cosmetic industry. In this study, we developed novel peptide mixture and identified its anti-pigmentation effect on melanocytes and keratinocytes. Our results revealed that peptide mixture inhibited melanosome biogenesis through the regulation of microphthalmia-associated transcription factor, a key factor of melanogenesis in melanocytes. And we observed that peptide mixture inhibited melanosome uptake through the reduction of protease-activated receptor 2, a phagocytosis-related receptor in keratinocytes. Furthermore, peptide mixture activated autophagy system resulting in degradation of transferred melanosomes in keratinocytes. The anti-pigmentation effect of multi-targeting peptide mixture was assessed in a human skin equivalent model (MelanoDerm). Melanin contents in epidermal layer were significantly decreased by topical treatment of peptide mixture, suggesting that it can be applied as a novel cosmetics material having a whitening function.

• 대한의용생체공학회:의공학회지
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• 제43권5호
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• pp.308-318
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• 2022

The purpose of this study is to evaluate the biomechanical properties of fractured adjacent soft tissue during closed reduction after forearm fracture using the finite element method. To accomplish this, a finite element (FE) model of the forearm including soft tissue was constructed, and the material properties reported in previous studies were implemented. Based on this, nine finite element models with different fracture types and fracture positions, which are the main parameters, were subjected to finite element analysis under the same load and boundary conditions. The load condition simulated the traction of increasing the fracture site spacing from 0.4 mm to 1.6 mm at intervals of 0.4 mm at the distal end of the radioulnar bone. Through the finite element analysis, the fracture type, fracture location, and displacement were compared and analyzed for the fracture site spacing of the fractured portion and the maximum equivalent stress of the soft tissues adjacent to the fracture(interosseous membrane, muscle, fat, and skin). The results of this study are as follows. The effect of the major parameters on the fracture site spacing of the fractured part is negligible. Also, from the displacement of 1.2 mm, the maximum equivalent stress of the interosseous membrane and muscle adjacent to the fractured bone exceeds the ultimate tensile strength of the material. In addition, it was confirmed that the maximum equivalent stresses of soft tissues(fat, skin) were different in size but similar in trend. As a result, this study was able to numerically confirm the damage to the adjacent soft tissue due to the fracture site spacing during closed reduction of forearm fracture.