• 제목/요약/키워드: skin elasticity test

검색결과 36건 처리시간 0.035초

아토피 피부염 환자들의 의복 소재 선호도 및 요구 성능 (A Study on the Preference and Requirement Performance for Clothing Materials of the Patients having Atopic Dermatitis)

  • 박영희
    • 복식문화연구
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    • 제16권4호
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    • pp.681-695
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    • 2008
  • This study was accomplished to investigate the preference of clothing materials and the clothing demand performance for underwear and everyday dress of atopic patients. As this study was the research study by a use of a questionnaire, the finally total 987 copies of the collected questionnaires were used to analyze the data. SPSS was used for the statistical analysis of data. To analyze the data, frequency analysis, percentage, $X^2$-test, reliability analysis, factor analysis, t-test, ANOVA and Duncan's multiple comparisons were used. The results obtained are as follows. In factor analysis for clothing materials and the demand performance which atopic patients favor, the preference factors for underwear materials were classified as pliability/a sense of weight, a sense of cold and warmth, tactility, and elasticity. Those for everyday wear were classified as pliability/surface roughness, a sense of cold and warmth, a sense of weight, and elasticity. And the demand performance factors for underwears were classified as thermophysiology, care convenience, and skin contact. Those for everyday wear were classified as comfortableness and care convenience. In the difference analysis for the preference and the demand performance, Both everyday wear and underwear showed a significant difference for the preference and the demand performance according to gender, age, income, education level, and occupation.

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세드롤과 콜라겐 유래 펩타이드의 피부노화 개선효과 (Anti-aging Effects of Cedrol and Collagen-derived Peptide)

  • 류종성;조환일;원지희;전미나;권오선;원보미;임준만;이상화
    • 대한화장품학회지
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    • 제41권3호
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    • pp.229-235
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    • 2015
  • 피부 노화는 피부 표면에 나타나는 현상으로 피부 표면의 미세구조와 연관이 있다. 피부 미세구조의 변화는 주름형성, 피부 톤 저하 등 다양한 피부 노화 현상을 유발하는 요인이 된다. 본 연구는 주름 기능성 성분인 세드롤(Cedrol)과 콜라겐 유래 펩타이드 성분을 이용하여 시험관 수준(in vitro)에서 타입III 콜라겐 합성 시너지 효과를 평가하였다. 여성 피시험자를 대상으로 4주 동안 상기 원료가 함유된 크림제품을 사용한 후 피부 미세구조, 스타 형상(star configurations), 보습, 탄력, 피부 밝기, 윤기, 피부 톤, 투명도를 평가하였다. 시험관 수준의 세드롤과 펩타이드를 동시에 처리하면 우수한 수준의 타입III 콜라겐 합성 시너지효과를 나타내었다. 그리고 크림제형을 이용한 인체적용 시험에서는 사용 4주 후부터 피부 미세구조, 스타형상, 윤기, 피부 톤, 보습, 탄력을 개선시켰으나, 피부 밝기 개선 효능은 나타나지 않았다. 본 연구를 통하여 기존 주름 기능성 성분인 세드롤과 콜라겐 유래 펩타이드는 세포 수준에서 타입III 콜라겐 합성 시너지 효과가 있음을 확인하였고 이를 화장품에 적용하여 시험한 결과 피부 노화 개선에 도움을 주는 성분임을 확인하였다.

산국 에센셜오일을 함유한 화장품의 주름개선 임상효능에 관한 연구 (A Study on the Anti-wrinkle Properties of Cosmetics Containing Essential Oil from Chrysanthemum boreale MAKINO)

  • 최인호;황대일;김도윤;김하빈;이환명
    • 생명과학회지
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    • 제29권4호
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    • pp.442-446
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    • 2019
  • 산국 에센셜오일의 채취시기별 특성과 in vitro 항산화, 미백, 피부재생 및 주름개선 활성이 본 연구진에 의해 최근 보고되었다. 본 연구는 산국 에센셜오일(0.1%, v/v)이 함유된 크림제형의 화장품에 대해 주름개선 효능 및 안전성을 확인하였다. 피시험자는 자연주름이 형성되어 있는 42세에서 60세까지의 22명의 여성을 대상으로 8주 동안 산국 에센셜오일 함유 화장품을 눈가주변에 도포하였다. 인체 피부 안전성은 피부과 전문의의 육안관찰 소견을 확보하고, 피부 주름개선 효능은 visiometer를 이용하여 roughness를 측정 하였다. 산국 에센셜오일 함유 화장품 및 대조시료는 시험기간 동안 인체에 홍반, 알러지 등의 이상반응을 유발하지 않았으며, 시험부위(test)는 대조부위(placebo)에 비해 roughness 지수 감소의 폭이 더 우수한 것으로 확인되었다. 또한 R1, R2, R3 지수는 크림 사용 2주 후부터 시험부위가 대조부위에 비해 통계적으로 유의(p<0.05)한 감소를 나타내었다. 따라서 "산국에센셜오일 함유 화장품"은 인체 안전성이 확보되었으며, 피부주름 개선 활성을 나타내는 것으로 확인되어 향후 비고시 주름개선 기능성화장품으로 개발이 가능할 것으로 사료된다.

글리세릴 베이스의 신규베지클 이용 캡슐화를 통한 항산화성 아스타잔틴의 성질 강화 (The Cosmeceutical Property of Antioxidant Astaxanthin is Enhanced by Encapsulation Using Glyceryl Based New Vesicle)

  • 김동명;홍원기;공수성;이정현
    • 대한화장품학회지
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    • 제40권3호
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    • pp.247-257
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    • 2014
  • 새로운 베지클인 glyceryl citrate/ lactate/ linoleate/ oleate를 이용한 수중유형 형태의 아스타잔틴 나노에멀젼에 대해 항산화 효과, 세포 생존력, 단백질과 관련한 효소의 영향, 피부 침투도 그리고 피부에 대한 보습 및 탄력 등의 약용화장품적인 측면에서의 전반적 연구를 실시하였다. 항산화력 및 세포 생존력에 대해선 각각 DPPH법과 MMT assay를 이용하여 측정하였다. 아스타잔틴 나노에멀젼에 대한 또 다른 성질은 2D-Page를 이용한 단백질 분석 및 컨포칼, in-vivo 테스트를 통해 측정하였다. 본 연구를 통해, 아스타잔틴을 포함하는 나노에멀젼은 MMP발현에 관련한 단백질 억제 및 세포외 기질의 분해를 막고 라디칼의 소거에 매우 우수한 결과를 보였다. 종전의 레시친을 이용한 나노에멀젼 보다는 새로운 베지클을 이용한 아스타잔틴 나노에멀젼의 피부 침투가 매우 효과적임을 CLSM을 통해 측정하였다. 또한 28일 동안의 한국 성인 여성 11명을 통한 보습 및 탄력 인비보 테스트에서 우수한 효과를 확인할 수 있었다.

Natural Ghana Cacao Powder의 Polyphenol 성분분석 및 피부개선효과 연구 (The Study of Composition Analysis of Natural Ghana Cacao Powder and Evaluation on its Skin Improvement Effect)

  • 심승보;오성근;전용진
    • 한국산학기술학회논문지
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    • 제12권5호
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    • pp.2434-2438
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    • 2011
  • 가나는 카카오의 최대산지이며, 카카오는 식품으로 이용하는 초코렛 재료가 되는 원료이며 오래전서부터 항산화 효과등이 알려져서 다양한 식품에 사용되어 왔다. 또한 가나산 카카오는 다른지역 카카오에 비해 폴리페놀 함량이 높은 것으로 알려져 왔으며 알칼리 처리를 하지 않아 약산성의 자연그대로의 특징이 남아 있다. 이 천연 가나산 카카오의 폴리페놀 함량을 분석하고 이것을 이용한 화장품 팩제를 개발하여 피부자극실험과 피부개선효과를 연구하였다. 그 결과 가나산 카카오파우더에는 약 3.6%의 탄닌성분이 포함 되어 있는 것으로 나타났으며 pH는 5.6을 나타내었고 가나산 카카오 파우더를 15% 함유한 팩제의 실험결과 일차피부자극실험에서는 피부자극이 나타나지 않았으며 120분후의 피부개선효과를 본 실험에서는 피부 수분량은 20%증가, 피부수분증발량은 17% 감소 피부pH는 5.3수렴, 피부탄력도는 24% 증가하는 것으로 나타나 피부개선 효과가 나타난 것으로 연구되었다.

부항요법(附缸療法)의 압력특성에 관한 실험적 연구 (Experimental Study on the Pressure Characteristics in the Cupping Therapy)

  • 김양중;김도호;염승철;임병철;최연성;이건휘;김형수;이재규;이건목
    • Journal of Acupuncture Research
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    • 제25권1호
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    • pp.121-130
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    • 2008
  • Objectives : Cupping therapy is a stimulation therapy similar to acupuncture and moxibustion with effects that differ depending on the degree of stimulus. To make the strength of the skin objective in cupping therapy for this study, we measured negative pressure in the cupping jar and calculated the expansion rate of the skin. Subjects and Methods : In this study, we experimented with cupping therapy jars made for sale and used in clinics. We studied the pressure in the jars and the changes on the skin surface by measuring properties. We used commercial jars of four different volumes and diameters and tried to discover the properties on the size of the jar. Results : The results of experiment with the cupping therapy are as follows: 1. The lowest pressure in a jar was measured at $-600{\sim}610mmHg$, and the number of operating of vacuum pump for reaching lowest pressure was increased recording where the volume of the jar would be big, but the lowest pressure was not increased recording where the size of that would be big. 2. As the vacuum pump continued to operate, the pressure gradient in the jar got smaller which shows that the expansion rate of the skin was not linear. The pressure gradient shows different operational numbers on the vacuum pump near 0mmHg/operation unrelated to jar volume. 3. When negative pressure worked on the jar, air in the jar decreased. The percentage of air gradually reduced as the negative pressure acted in the jar. For example, the percentage of skin was 37-66% when the negative pressure, reatched -500mmHg. According to out results, different test areas generate different percentages of air in the jar, presumably related to skin elasticity. This phenomenon was most pronounced with the smallest jars. 4. At -500mmHg, the expansion rate of the skin was 1.57-1.9 on the abdomen, and $1.52{\sim}1.68$ on the back. The expansion rate of the skin appeared greater when the jar was relatively small, and it appeared smaller when the jar volume was relatively large relatively.

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Study on Application of Skin Care Cosmetic and Stabilization of Idebenone by Forming Niosome Vesicle Technology

  • Kim, In-Young
    • 한국응용과학기술학회지
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    • 제36권2호
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    • pp.592-599
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    • 2019
  • This study is to stabilize insoluble and unstable active ingredient which is Idebenone (INCI name: hydroxydecyl ubiquinone) in a multi-lamellar vesicle (MLV) and to stabilize it in the skin care cosmetics. Idebenone is good effective raw material in the treatment of Alzheimer's disease in the medical field and a powerful antioxidant in dermatology. It is well known as a substance that inhibits the formation of melanin and cleans the skin pigment. However, it did not dissolve in any solvent and it was difficult to apply in cosmetic applications. Niosome vesicle was able to develop a nano-particle by making a multi-layer of idebenone encapsulated with a nonionic surfactant, hydrogenated lecithin and glycine soja (soybean) sterols and passing it through a high pressure microfluidizer. Idebenone niosome vesicle (INV) has been developed to have the ability to dissolve transparently in water and to promote transdermal penetration. The appearance of the INV was a yellowish liquid having specific odor, and the particle size distribution of INV was about 10~80 nm. The pH was 5~8 (mean=6.8). This capsulation with idebenone was stored in a $45^{\circ}C$ incubator for 3 months and its stability was observed and quantitatively measured by HPLC. As a result, the stability of the sample encapsulated in the niosome vesicle (97.5%) was about 66.3% higher than that of the non-capsule sample of 32.5%. Idebenone 1% INV was used for the efficacy test and clinical trial evaluation as follows. The anti-oxidative activity of INV was 38.2%, which was superior to that of 12.8% tocopherol (control). The melanin-reducing effect of B16 melanoma cells was better than INV (17.4%) and Albutin (control) (9.6%). Pro-collagen synthesis rate was 128.2% for INV and 89.3% for tocopherol (control). The skin moisturizing effect was 15.5% better than the placebo sample. The elasticity effect was 9.7% better than the placebo sample. As an application field, INV containing 1% of idebenone is expected to be able to develop various functional cosmetic formulations such as skin toner, ampoule essence, cream, eye cream and sunblock cream. In addition, it is expected that this encapsulated material will be widely applicable to emulsifying agents for skin use in the pharmaceutical industry as well as the cosmetics industry.

3-O-cetyl-L-ascorbic acid의 주름 개선 효과 (Anti-wrinkle effect of 3-O-cetyl-L-ascorbic acid)

  • 박창민;이순영;정민석;최종완
    • 대한화장품학회지
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    • 제34권4호
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    • pp.303-309
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    • 2008
  • 건강한 피부 기능의 악화 원인으로는 콜라겐 섬유 감소, 탄력섬유 변성, 활성산소종의 과다 생성 등이 있다. 이로 인하여 피부 탄력 저하나 주름이 생성된다. 피부 탄력 저하 및 주름 생성과 같은 피부 노화를 개선하기 위해 대표적으로 비타민 A, C 및 그 유도체들이 화장품에 적용되고 있지만 화학적 불안정성의 문제점이 있어 새로운 유도체들의 합성 개발에 노력을 기울이고 있다. 본 연구에서는 피부개선을 위한 화장품 원료로 최근 비타민 C로부터 새롭게 합성된 3-O-cetyl-L-ascorbic acid (VCCE)의 주름 개선과 관련된 효능 효과를 평가하였다. VCCE의 in vitro 실험 결과 procollagen type I의 합성을 0.002%에서 최대 149% 증가시켰다. 또한 인체적용시험에서 일차적으로 폐쇄 첩포 실험 결과 자극이 유발되지 않았으며, 모사판 분석 및 PRIMOS system을 이용한 주름측정결과에서도 주름개선효과를 확인하였다. 결과적으로, VCCE는 주름 개선을 위한 화장품 성분으로서 높은 응용 가치를 제시한다.

훈제 처리가 가열소지에 미치는 영향 (The effect of smoking on the quality boiled sausage)

  • 정청송;유상훈
    • 한국관광식음료학회지:관광식음료경영연구
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    • 제12권2호
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    • pp.1-41
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    • 2001
  • The effect of smoking on the quality sausage Sausages were prepared from beef, port, chickens, games, fish and shellfish with polyphosphate salt and spices. Sausage history goes back to 3,000 years of age. The procedure of sausage 1) Meat Curing 2) Meat Control 3) Add Spices 4) Permissible Ingredients 5) Grinding 6) Mixing Emulsion 7) Stuffing 8) Showing 9) Smoking 10) Cooking 11) Drying 12) Packaging Sausage Product to get information on the effect of smoking onto the quality of meat produces. Sausage was smoked under a given conditions. Smoking was conducted as 35f$^{\circ}C$to 6$0^{\circ}C$ the related humidity of smokehouse was still at 60 to 70 percent. Results are as follows: 1. The Penetrated smoke in sausage was prolonged < p.<0.02 when sausage was smoked 2hours at 60~$65^{\circ}C$ the penetrated amount of free acetone in sausage was 0.5mg%. 2. Peroxide value of sausage as heating treatment both at 3$0^{\circ}C$ and at 5$0^{\circ}C$ was prolonged. 3. When sausage was heated at 3$0^{\circ}C$, bacteria of sausage increased In number while at 60~$65^{\circ}C$ bacteria of sausage increased In number fourteen hours. 4. When sausage was treated with smoking the distribution of free amino acids in sausage was changed markedly. 5. The longer smoking time of the products was the higher the content. 6. In case of oak wood smoke flavoring all of test samples. 7. Rapid decrease of does-response mutagenic curve of the smoke flavoring of oak wood and apple wood by in the peak of curve and phenol in the smoke flavoring. Continuous efforts are required to make sausages easily in the butcher shops and in the restaurants. 8. Sausage texture evaluation has 13 rules. It is Elasticity, Surface Moisture, Surface Smoothness, Center Hardness, Skin Toughness, Cohesiveness, Denseness, Moisture Release, Cohesiveness of Mass, Lumpiness, Graininess (of Contents), Skin separation, Oiliness and sensory 11 rules evaluation is color, texture, mold, flavor, sweet test, salty, sourness, bitter, and savory taste. 9. Smoked, component, peroxide value, bacteria, color, free amino acid, tenderness, flavor, shrinkage are important values.

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Development of Hair Keratin Protein to Accelerate Oral Mucosal Regeneration

  • So-Yeon Kim
    • 치위생과학회지
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    • 제23권4호
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    • pp.369-377
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    • 2023
  • Background: In this study, we investigated the potential use of keratin for oral tissue regeneration. Keratin is well-known for its effectiveness in skin regeneration by promoting keratinization and enhancing the elasticity and activity of fibroblasts. Because of its structural stability, high storability, biocompatibility, and safety in humans, existing research has predominantly focused on its role in skin wound healing. Herein, we propose using keratin proteins as biocompatible materials for dental applications. Methods: To assess the suitability of alpha-keratin protein as a substrate for cell culture, keratin was extracted from human hair via PEGylation. Viabilities of primary human gingival fibroblasts (HGFs) and human oral keratinocytes (HOKs) were assessed. Fluorescence immunostaining and migration assays were conducted using a fluorescence microscope and confocal laser scanning microscope. Wound healing and migration assays were performed using automated software to analyze the experimental readout and gap closure rate. Results: We confirmed the extraction of alpha-keratin and formation of the PEG-g-keratin complex. Treatment of HGFs with keratin protein at a concentration of 5 mg/ml promoted proliferation and maintained cell viability in the test group compared to the control group. HOKs treated with 5 mg/ml keratin exhibited a slight decrease in cell proliferation and activity after 48 hours compared to the untreated group, followed by an increase after 72 hours. Wound healing and migration assays revealed rapid closure of the area covered by HOKs over time following keratin treatment. Additionally, HOKs exhibited changes in cell morphology and increased the expression of the mesenchymal marker vimentin. Conclusion: Our study demonstrated the potential of hair keratin for soft tissue regeneration, with potential future applications in clinical settings for wound healing.