• Title/Summary/Keyword: size-dependent

Search Result 1,996, Processing Time 0.03 seconds

A Study on the Analysis of Dangerous Driving Behavior and Traffic Accident Risk according to the Operation Characteristics of Commercial Freight Vehicles (사업용 화물자동차 운행특성에 따른 위험운전행동 및 교통사고 위험도 분석 연구)

  • Park, Jin soo;Lee, Soo beom;Park, Jun tae
    • The Journal of The Korea Institute of Intelligent Transport Systems
    • /
    • v.21 no.2
    • /
    • pp.152-166
    • /
    • 2022
  • This study analyzed the causal relationship among operating characteristics of commercial freight vehicles, dangerous driving behaviors, and traffic accident risk. The study applied the existing accident cause and prevention theory to arrive at this relationship. Data related to working characteristics of driver, driving experience, driving ability, driving psychology, vehicle characteristics (size), dangerous driving behavior, and traffic accidents were collected from 303 commercial freight vehicle drivers. Working characteristics and dangerous driving behavior data are based on the driver's digital driving record. The traffic accident data is based on the insurance accident data reflecting actual traffic accidents. First, a structural equation model was built and verified using the model fitness index. Then, the developed model was used to analyze the causal relationship between multiple independent and dependent variables simultaneously. Four dangerous driving behaviors (sudden deceleration, sudden acceleration, sudden passing, and sudden stop) were found to be highly related to traffic accidents. The results further indicate that it is necessary to establish a safety management policy and intensive management for small-sized freight vehicles, drivers with insufficient driving ability, and drivers with dangerous driving behaviors. Such policy and management are expected to reduce traffic accidents effectively.

Characteristics of Glycyrrhiza uralensis extract-loaded chitosan nanocapsules and their antioxidant activity (감초 추출물 함유 키토산 나노캡슐의 특성 및 항산화 활성)

  • Kim, Min Jung;Lee, Ji-Soo;Lee, Hyeon Gyu
    • Korean Journal of Food Science and Technology
    • /
    • v.53 no.4
    • /
    • pp.479-485
    • /
    • 2021
  • To improve the oxidative stability of Glycyrrhiza uralensis extract (GU), GU extraction conditions were optimized for maximal antioxidant activity, and GU-loaded nanocapsules were prepared by chitosan ionic gelation. The optimized ethanol concentration and extraction time were 83.0% and 32.6 min, respectively, using response surface methodology. The particle size of the GU-loaded nanocapsules ranged from 280 to 370 nm. A GU extract of 0.8 mg/mL and chitosan concentration of 2.0 mg/mL were selected as the optimal conditions for entrapment and loading efficiency. Both free GU and GU-loaded chitosan nanocapsules exhibited concentration-dependent antioxidant activity. However, the antioxidant protection factor of GU was effectively maintained when it was entrapped within the chitosan nanocapsules. In conclusion, chitosan nanoencapsulation is a potentially valuable technique for improving the oxidative stability of GU.

The Impact of Government Development Policy on Land Investment and Land Price: Evidences from Linyi (토지개발 및 토지가격에 대해서 정부 개발 정책의 영향 린이시 중심으로)

  • Zhong, Shengyang;Zheng, Ziyang;Liu, Zhao
    • The Journal of the Korea Contents Association
    • /
    • v.21 no.12
    • /
    • pp.337-347
    • /
    • 2021
  • Land is key natural resource that Chinese government actually owns. Real estate and land development have played an important part in China's urban development and economic development. The Chinese local governments' land development policies can mainly be characterized as the establishment of economic development zones and the development of new towns. Given the great importance of these measures, we can expect that these policies can generate noticeable impacts on land development and land price. However, little research has explored these impacts empirically. Using the data collected from land development projects of three districts in Linyi city-old town, new town, economic development zone, this paper attempts to investigate the impact of government development policy on land development and land price. This research chooses investment amount and land price as dependent variables. The multiple regression results demonstrate that the local government's land Development policies can affect land investment size and land price significantly. As we have noticed, the target of government development policy is to make use of urban land resources more scientifically and efficiently. Based on my empirical analysis, some useful insights can be provided for improving our understanding concerning the effects of these government land development policies.

Overexpression of cholinergic receptor nicotinic gamma subunit inhibits proliferation and differentiation of bovine preadipocytes

  • Jiawei, Du;Hui, Zhao;Guibing, Song;Yuan, Pang;Lei, Jiang;Linsen, Zan;Hongbao, Wang
    • Animal Bioscience
    • /
    • v.36 no.2
    • /
    • pp.200-208
    • /
    • 2023
  • Objective: Muscle acetylcholine receptors have five alpha subunits (α, β, δ, ε, or γ), and cholinergic receptor nicotinic gamma subunit (CHRNG) is the γ subunit. It may also play an essential role in biological processes, including cell differentiation, growth, and survival, while the role of CHRNG has not been studied in the literature. Therefore, the purpose of this study is to clarify the effect of CHRNG on the proliferation and differentiation of bovine preadipocytes. Methods: We constructed a CHRNG overexpression adenovirus vector and successfully overexpressed it on bovine preadipocytes. The effects of CHRNG on bovine preadipocyte proliferation were detected by Edu assay, cell counting Kit-8 (CCK-8), real-time fluorescence quantitative polymerase chain reaction (RT-qPCR), Western blot and other techniques. We also performed oil red O, RT-qPCR, Western blot to explore its effect on the differentiation of preadipocytes. Results: The results of Edu proliferation experiments showed that the number of EDU-positive cells in the overexpression group was significantly less. CCK-8 experiments found that the optical density values of the cells in the overexpression group were lower than those of the control group, the mRNA levels of proliferating cell nuclear antigen (PCNA), cyclin A2 (CCNA2), cyclin B1 (CCNB1), cyclin D2 (CCND2) decreased significantly after CHRNG gene overexpression, the mRNA levels of cyclin dependent kinase inhibitor 1A (CDKN1A) increased significantly, and the protein levels of PCNA, CCNB1, CCND2 decreased significantly. Overexpression of CHRNG inhibited the differentiation of bovine preadipocytes. The results of oil red O and triglyceride determination showed that the size and speed of lipid droplets accumulation in the overexpression group were significantly lower. The mRNA and protein levels of peroxisome proliferator activated receptor gamma (PPAR class="checkNonKBPoint">γ), CCAAT enhancer binding protein alpha (CEBPα), fatty acid binding protein 4 (FABP4), fatty acid synthase (FASN) decreased significantly. Conclusion: Overexpression of CHRNG in bovine preadipocytes inhibits the proliferation and differentiation of bovine preadipocytes.

Efficient Extraction Method of Black Tea using Mineral Water and Antioxidant and Anti-inflammatory Activity of Extract (미네랄 워터를 이용한 블랙티의 효율적 추출 방법 및 추출물의 항산화와 항염 효능)

  • Kim, Eun-Mi;Jung, Jiyong;Kim, Hyung-Min;Hwang, Kyeong Hwan;Kim, Hyoung-June;Park, Won-Seok
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.48 no.1
    • /
    • pp.47-53
    • /
    • 2022
  • In this study, the conditions for efficiently extracting polyphenols contained in black tea were optimized. In order to confirm the polyphenol content according to the degree of fermentation, the polyphenol content in black tea of the three fermentation degrees was compared. As the degree of fermentation increased, the polyphenol content increased, and it was confirmed that the theabrownin content, the largest in size, increased significantly. In addition, it was confirmed that the amount of theabrownin extraction increased by about 150% or more compared to other extraction water when extracting using mineral water, which was hard water. The antioxidant effects of black tea extract and the theabrownin was confirmed using ABTS assay. As a result, both extracts had antioxidant effects, and IC50 values were confirmed to be 10.60 ppm and 13.21 ppm, respectively. And also, the anti-inflammatory effect of the theabrownin was confirmed that the mRNA expression of IL-8 increased by UVB irradiation was inhibited in a concentration dependent manner by the theabrownin. In addition, when theabrownin was treated with 10 ppm, the mitochondrial function decreased by UVB irradiation was restored to 86 ± 1.9% compared to the control group. Therefore, we concluded that theabrownin could protect mitochondrial damage caused by UVB irradiation.

An effect of Internal Audit of IATF 16949 Automotive Quality Management System on the Performance of Organization (IATF 16949 자동차 품질경영시스템 내부심사가 조직의 성과에 미치는 영향)

  • Joo, Daesung;Lee, Moonsu
    • Journal of Practical Engineering Education
    • /
    • v.14 no.1
    • /
    • pp.37-48
    • /
    • 2022
  • This study analyzed the effect of internal audit on the performance of the IATF 16949 automotive quality management system to understand the internal audit of companies and propose measures to activate the company's internal audit process. It was identified with the empirical analysis that 'The internal auditor competence, internal audit planning, internal audit implementation, infrastructure, culture/environment, and CEO support' to characterize IATF 16949 internal audit of automotive quality management system affects the internal performance and business performance of the company. In addition, I checked the size of the company and the period of certification period as moderating variables according to the sales based on the presented as factors that can improve the performance of the company, and how the moderating effects are seen in the relationship with the performance of the organization. I did analysis of technical statistics, exploratory factors, reliability, and multi-regression analysis with SPSS program. I summarized the results of the study, as a result of that, it was found that the internal audit planning, internal audit implementation, culture/ environment, and CEO support of independent variables affected the parameter and dependent variables (the internal performance and management performance of companies).

The Algorithm for an Energy-efficient Particle Sensor Applied LEACH Routing Protocol in Wireless Sensor Networks (무선센서네트워크에서 LEACH 라우팅 프로토콜을 적용한 파티클 센서의 에너지 효율적인 알고리즘)

  • Hong, Sung-Hwa;Kim, Hoon-Ki
    • Journal of the Korea Society for Simulation
    • /
    • v.18 no.3
    • /
    • pp.13-21
    • /
    • 2009
  • The sensor nodes that form a wireless sensor network must perform both routing and sensing roles, since each sensor node always has a regular energy drain. The majority of sensors being used in wireless sensor networks are either unmanned or operated in environments that make them difficult for humans to approach. Furthermore, since many wireless sensor networks contain large numbers of sensors, thus requiring the sensor nodes to be small in size and cheap in price, the amount of power that can be supplied to the nodes and their data processing capacity are both limited. In this paper, we proposes the WSN(Wireless Sensor Network) algorithm which is applied sensor node that has low power consumption and efficiency measurement. Moreover, the efficiency routing protocol is proposed in this paper. The proposed algorithm reduces power consumption of sensor node data communication. It has not researched in LEACH(Low-Energy Adaptive Clustering Hierarchy) routing protocol. As controlling the active/sleep mode based on the measured data by sensor node, the energy consumption is able to be managed. In the event, the data is transferred to the local cluster head already set. The other side, this algorithm send the data as dependent on the information such as initial and present energy, and the number of rounds that are transformed into cluster header and then transferred. In this situation, the assignment of each node to cluster head evenly is very important. We selected cluster head efficiently and uniformly distributed the energy to each cluster node through the proposed algorithm. Consequently, this caused the extension of the WSN life time.

Influence of Rainfall Intensity and Saturated Permeability on Slope Stability during Rainfall Infiltration (강우침투시 강우강도와 포화투수계수가 안전율에 미치는 영향)

  • Lee, Seung-Rae;Oh, Tae-Kyu;Kim, Yun-Ki;Kim, Hee-Chul
    • Journal of the Korean Geotechnical Society
    • /
    • v.25 no.1
    • /
    • pp.65-76
    • /
    • 2009
  • The unsaturated characteristics of Korean weathered granite soils have been studied to investigate the influence of saturated permeability, rainfall intensity and soil-water characteristic curve (SWCC) on the slope stability. The upper, average and lower SWCCs were estimated from the publication and experimental results using the statistical concept. The roughly estimated SWCC can be used for the soils without experimental results by relating SWCC with the particle size distribution curve. An appropriate ratio between the saturated permeability and the rainfall intensity ($k_s$/i) was also suggested for practical use in designing the slopes by investigating the time-dependent variation of slope instability during the rainfall. The slope stability was deteriorated from the initiation of rainfall and recovered again after the factor of safety reached the critical value. The FS of the slope decreased at first and then increased after reaching the critical value during the rainfall. As a result, the slope instability was not related with an absolute rainfall intensity but with the ratio between the saturated permeability and the rainfall intensity. In case of the upper SWCC, the critical condition occurred when the ratio between the saturated permeability and the rainfall intensity was in the range of $1.0{\sim}2.0$.

A Multilevel Analysis about the Impact of Patient's Willingness for Discharge on Successful Discharge from Long-term Care Hospitals (퇴원 의지가 요양병원의 성공적 퇴원에 미치는 영향에 대한 다수준 분석)

  • Ghang, Haryeom;Lee, Yeonju
    • Health Policy and Management
    • /
    • v.32 no.4
    • /
    • pp.347-355
    • /
    • 2022
  • Background: Since November 2019, long-term care hospitals have been able to provide patients with discharging programs to support the elderly in the community. This study aimed to identify both patient- and hospital-level factors that affect successful community discharge from long-term care hospitals. Methods: A multilevel logistic regression model was performed using hospitals as a clustering unit. The dependent variable was whether a patient stayed in the community for at least 30 days after discharge from a long-term care hospital. As for the patient-level independent variables, an agreement between a patient and the family about discharge, length of hospital stay, patient category, and residence at discharge were included. The number of beds and the ratio of long-stay patients were selected for the hospital-level factors. The sample size was 1,428 patients enrolled in the discharging program from November 2019 to December 2020. Results: The number of patients who were discharged to the community and stayed at least for 30 days was 532 (37.3%). The intraclass correlation coefficient was 22.9%, indicating that hospital-level factors had a significant impact on successful community discharge. The odds ratio (OR) of successful community discharge increased by 1.842 times when the patients and their families agreed on discharge. The ORs also increased by 3.020 or 2.681 times, respectively when the patients planned to discharge to their own house or their child's house compared to those who didn't have a plan for residence at discharge. The ORs increased by 1.922 or 2.250 times when the hospitals were owned by corporate or private property compared to publicly owned hospitals. The ORs decreased by 0.602 or 0.520 times when the hospital was sized over 400 beds or located in small and medium-sized cities compared to less than 200 bedded hospitals or located in metropolitan cities. Conclusion: The results of the study showed that the patients' and their family's willingness for discharge had a great impact on successful community discharge and the hospital-level factors played a significant role in it. Therefore, it is important to acknowledge and support long-term care hospitals to involve active in the patient discharge planning process.

Comparison of Nutritional Knowledge, Dietary Habits, and Practice Level of Eating Behavior Guidelines Between Part-Time Working and Non-Working Adolescents Attending a Vocational High School in Yongin, Gyeonggi-Do (용인지역 일부 실업계 고등학생의 아르바이트 여부에 따른 영양지식, 식습관, 식생활 지침 실천도 비교)

  • Bae, Sung-Joo;Lee, Seung-Min;Ahn, Hong-Seok
    • Journal of the Korean Society of Food Culture
    • /
    • v.25 no.1
    • /
    • pp.17-24
    • /
    • 2010
  • The purpose of this study was to investigate nutritional knowledge, practice of eating behavior guidelines, and problematic dietary habits in working high school students in comparison with non-working high school students. A survey questionnaire was formulated to obtain information on demographic variables, body size, part-time jobs, nutritional knowledge, practice of eating behavior guidelines, and dietary habits. The developed questionnaire was given out to 515 students attending a vocational high school in Yongin, Gyeonggi-Do. Those who had been working 5 hours or more per day for at least a month at the time of survey administration were defined as working students for this study. Proportions of working students were similar between male and female students (i.e. 49.5% for male, 50.5% for female). No significant difference was found in scores of nutritional knowledge between working ($8.43{\pm}2.29$) and non-working students ($8.60{\pm}2.19$). However, some dietary habits were found to be dependent on working status. While approximately 43% of non-working students reported skipping a meal, about 57% of working students did so (p<0.01). The proportion of students with any drinking experience was significantly higher among working students (92%) compared to non-working students (80%) (p<0.001). Working students were found to drink alcoholic beverages more often than non-working students (p<0.001). The mean score of practice of eating behavior guidelines was lower in working students than non-working students. The magnitude of this difference was modest ($51.33{\pm}0.63$ in working students, $53.40{\pm}0.51$ in non-working students), but reached statistical significance (p<0.01). Based on the findings from this study, it is suggested that specific behavior-oriented messages to improve certain problematic dietary habits need to be directed toward working high school students.