• Molecules and Cells
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• v.38 no.9
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• pp.789-795
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• 2015

A chromosome territory is composed of chromosomal subdomains. The internal structure of chromosomal subdomains provides a structural framework for many genomic activities such as replication and DNA repair, and thus is key to determining the basis of their mechanisms. However, the internal structure and regulating proteins of a chromosomal subdomain remains elusive. Previously, we showed that the chromosome territory expanded after BAF53 knockdown. Because the integrity of chromosomal subdomains is a deciding factor of the volume of a chromosome territory, we examined here the effect of BAF53 knockdown on chromosomal subdomains. We found that BAF53 knockdown led to the disintegration of histone H2B-GFP-visualized chromosomal subdomains and BrdU-labeled replication foci. In addition, the size of DNA loops measured by the maximum fluorescent halo technique increased and became irregular after BAF53 knockdown, indicating DNA loops were released from the residual nuclear structure. These data can be accounted for by the model that BAF53 is prerequisite for maintaining the structural integrity of chromosomal subdomains.

• 한국신재생에너지학회:학술대회논문집
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• 2010.11a
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• pp.122.2-122.2
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• 2010

Knowledge of ground thermal properties is most important for the proper design of BHE(borehole heat exchanger) systems. The configure type, pipe size and thermal performance of the BHE is highly dependent on the ground source heatpump system-efficiency and instruction cost. Thermal response tests with mobile measurement devices were developed primarily for in-situ determination of design data for Standing Column Well apply. The main purpose has been to determine in-situ values of effective ground thermal conductivity and thermal resistance, including the effect of ground-water flow and natural convection in the boreholes. The test rig is set up on a some trailer, and contains a sub-circulation pump, a boiler, temperature sensors, flow meter and a data logger for recording the temperature and circulation fluid flow data. A constant heating power is injected into the SCW through the test rig and the resulting temperature change in the SCW is recorded. The recorded temperature data are analysed with a line-source model, which gives the effective in-situ values of rock thermal conductivity and thermal resistance of SCW.

• Advances in nano research
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• v.9 no.3
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• pp.157-172
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• 2020

The aim of this present research is the effect of the higher-order terms of the governing equation on the forced longitudinal vibration of a nanorod model and making comparisons of the results with classical nonlocal elasticity theory. For this purpose, the free axial vibration along with forced one under the two various linear and harmonic axial concentrated forces in zigzag Single-Walled Carbon Nanotube (SWCNT) are analyzed dynamically. Three various theories containing the classical theory, which is called Eringen's nonlocal elasticity, along with Rayleigh and Bishop theories (higher-order theories) are established to justify the nonlocal behavior of constitutive relations. The governing equation and the related boundary conditions are derived from Hamilton's principle. The assumed modes method is adopted to solve the equation of motion. For the free axial vibration, the natural frequencies are calculated for the various values of the nonlocal parameter only based on Eringen's theory. The effects of the nonlocal parameter, thickness, length, and ratio of the excitation frequency to the natural frequency over time in dimensional and non-dimensional axial displacements are investigated for the first time.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.12
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• pp.959-968
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• 2020

Tourist loyalty is created through good tourism service quality and the availability of tourism products. This study discussed the various attributes of tourism service quality, namely, tour agents, efficient personnel, accessible transportation, and information service quality. Whereas for tourism product availability attributes were varieties of product availability, wide selection of tour agents and tourist products, and wide variety of amenity services. As a general rule, the minimum is to have at least five times as many observations as the number of variables to be analyzed, and the more acceptable sample size would have a 10:1 ratio. A total of 424 questionnaires were returned, with 35 removed due to errors. Finally, 389 questionnaires respondents were used via accidental sampling method through the distribution of questionnaires to foreign tourists at Soekarno Hatta International Airport. In addition, AMOS 7.0 software is used to test models in confirmatory factor analysis (CFA) as well as hypothetical testing using structural equation modeling (SEM). The results showed that all hypotheses were accepted, except for the effect of tourism service quality on tourist loyalty in Indonesia. This research aims to contribute significantly to the existing knowledge of tourism, specifically from a foreign tourist perspective in Indonesia.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.12
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• pp.389-395
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• 2020

Earnings management is a matter of concern for organizations because it affects the interests of stakeholders. This reduces the quality of information on financial statements of the organizations when the organization performs earnings management behavior. The objective of the article is to examine the impact of corporate governance on earnings management of all Vietnamese listed banks from 2015 to 2019. The article uses time-series data and ordinary least square (OLS) with Eviews 10.0 software to test the regression model. The agency and asymmetry information theory is used to explain the relationship between corporate governance and earnings management. The study results show that two variables - the foreign members of the board of directors and audit committee - have an opposite effect on earnings management behavior of Vietnamese listed banks. Therefore, the managers of listed banks need to raise awareness to express responsibility for honest and reasonable information on the financial statements. This creates trust and credibility for stakeholders. Moreover, Central bank of Vietnam should monitor regularly and enforce strict sanctions to limit earnings management behavior of listed banks. This contributes to improving the quality of accounting information in the Vietnamese banking sector to meet the trend of international economic integration.

• Steel and Composite Structures
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• v.36 no.6
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• pp.643-656
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• 2020

This article presents a comprehensive static analysis of simply supported cross-ply carbon nanotubes reinforced composite (CNTRC) laminated nanobeams under various loading profiles. The nonlocal strain gradient constitutive relation is exploited to present the size-dependence of nano-scale. New higher shear deformation beam theory with hyperbolic function is proposed to satisfy the zero-shear effect at boundaries and parabolic variation through the thickness. Carbon nanotubes (CNTs), as the reinforced elements, are distributed through the beam thickness with different distribution functions, which are, uniform distribution (UD-CNTRC), V- distribution (FG-V CNTRC), O- distribution (FG-O CNTRC) and X- distribution (FG-X CNTRC). The equilibrium equations are derived, and Fourier series function are used to solve the obtained differential equation and get the response of nanobeam under uniform, linear or sinusoidal mechanical loadings. Numerical results are obtained to present influences of CNTs reinforcement patterns, composite laminate structure, nonlocal parameter, length scale parameter, geometric parameters on center deflection ad stresses of CNTRC laminated nanobeams. The proposed model is effective in analysis and design of composite structure ranging from macro-scale to nano-scale.

• Structural Engineering and Mechanics
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• v.73 no.6
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• pp.685-698
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• 2020

The dynamic stability of a functionally graded polymer microbeam reinforced by graphene oxides subjected to a periodic axial force is investigated. The microbeam is assumed to rest on an elastic substrate and is subjected to various immovable boundary restraints. The weight fraction of graphene oxides nanofillers is graded across the beam thickness. The effective Young's modulus of the functionally graded graphene oxides reinforced composite (FG-GORC) was determined using modified Halpin-Tsai model, with the mixture rule used to evaluate the effective Poisson's ratio and the mass density. An improved third order shear deformation theory (TSDT) is used in conjunction with the Chebyshev polynomial-based Ritz method to derive the Mathieu-Hill equations for dynamic stability of the FG-GORC microbeam, in which the scale effect is taken into account based on modified couple stress theory. Then, the Mathieu-Hill equation was solved using Bolotin's method to predict the principle unstable regions of the FG-GORC microbeams. The numerical results show the effects of the small scale, the graphene oxides nanofillers as well as the elastic substrate on the dynamic stability behaviors of the FG-GORC microbeams.

• Geomechanics and Engineering
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• v.9 no.4
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• pp.513-530
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• 2015

Commonly, the base stability of sheeted excavation pits against seepage failure by heave is evaluated by using two-dimensional groundwater flow models and Terzaghi's failure criterion. The objective of the present study is to investigate the effect of three-dimensional groundwater flow on the heave for sheeted excavation pits with various dimensions. For this purpose, the steady-state groundwater flow analyses are performed by using the finite element program ABAQUS 6.12. It has been shown that, in homogeneous soils depending on the ratio of half of excavation width to embedment depth b/D, the ratio of safety factor obtained from 3D analyses to that obtained from 2D analyses $FS_{(3D)}/FS_{(2D)}$ can reach up to 1.56 and 1.34 for square and circular shaped excavations, respectively. As failure body, both an infinitesimal soil column adjacent to the wall (Baumgart & Davidenkoff's criterion) and a three-dimensional failure body with the width suggested by Terzaghi for two-dimensional cases are used. It has been shown that the ratio of $FS_{(Terzaghi)}/FS_{(Davidenkoff)}$ varies between 0.75 and 0.94 depending on the ratio of b/D. Additionally, the effects of model size, the shape of excavation pit and anisotropic permeability on the heave are studied. Finally, the problem is investigated for excavation pits in stratified soils, and important points are emphasized.

• Asian Journal of Business Environment
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• v.9 no.2
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• pp.5-15
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• 2019

Purpose - The present study endeavours to investigate the impact of intellectual capital (IC) and its components on corporate sustainable growth in India. In addition, this study aims to find out the most influential component of IC on corporate sustainable growth in India. Research design, data, and methodology - A sample size of top 139 NSE listed non-financial companies over a time period of five years has been used in this monograph. The impact of intellectual capital and its components on corporate sustainable growth has been examined using the longitudinal data analysis technique. Results - The findings of this study bring to light that intellectual capital (IC) as measured by the M-VAIC model demonstrates a significant impact on corporate sustainable growth. Considerably, the results also reveal that almost all the explanatory variables viz. Physical Capital, Relational Capital, Innovation Capital, and Process Capital exercise notable influence in explaining corporate sustainable growth. Moreover, the results demonstrate Innovation Capital (controlling the effect of Physical Capital) represents the most influential component of IC on corporate sustainable growth. Conclusions - The research findings show that in the Indian context, both physical capital, and IC (overall), as well as its components, play a crucial role to explain corporate sustainable growth.

• Advances in nano research
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• v.8 no.3
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• pp.191-202
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• 2020

The article brings the study of nonlocal, surface and the couple stress together to apparent the frequency retaliation of FG nanobeams (Functionally graded). For the examination of frequency retaliation, the article considers the accurate spot of neutral axis. This article aims to enhance the coherence of proposed model to accurately encapsulate the significant effects of the nonlocal stress field, size effects together with material length scale parameters. These considered parameters are assimilated through what are referred to as modified couple stress as well as nonlocal elasticity theories, which encompasses the stiffness-hardening and softening influence on the nanobeams frequency characteristics. Power-law distribution is followed by the functional gradation of the material across the beam width in the considered structure of the article. Following the well-known Hamilton's principle, fundamental basic equations alongside their correlated boundary conditions are solved analytically. Validation of the study is also done with published result. Distinct parameters (such as surface energy, slenderness ratio, as nonlocal material length scale and power-law exponent) influence is depicted graphically following the boundary conditions on non-dimensional FG nanobeams frequency.