• Archives of Reconstructive Microsurgery
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• v.16 no.2
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• pp.57-62
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• 2007

Non-vascularized free composite graft is one of the simple and effective reconstructive options, but its clinical use has been limited due to questionable survival rate. Early vascularization is essential for graft survival and is mainly carried out via recipient bed or repaired sites. This study was designed to investigate the effect of the lateral marginal approximations on the survival of the free composite flap using a model of skin-subcutaneous composite graft in rats. Thirty 1.5 ${\times}$ 1.5 $cm^2$ sized square shape composite flaps were elevated freely and reposed in place immediately on the dorsum of five Sprague-Dawley rats, and divided into five groups of six flaps. In all groups, graft bed was isolated with silastic sheet. In the group I, all sides of flap were repaired with blockage of silastic sheet insertion. Three, two, and one sides of flap were treated with same method in the group II, III, and IV respectively. Other sides of flaps were repaired without blockage, so all sides of flap were repaired in the group V. At 14 days later, the survived rate of each flap was evaluated according to the numbers of the repair sites. Histological examination was done for the evaluation of new vessel development quantitatively. Overall survived rates were increased with the number of repaired sites, but the group V only showed increased survival rate up to more than fifty percentile of the flap size with a significant difference statistically. New vessels were also increased in proportion with the number of repaired sites, and the repair site more than two had significant effect on the increased number of new vessels. In conclusion, at least more than three-fourth of flap circumference should be repaired in order to increase flap survival effectively under the condition of bed isolation.

• Journal of Digital Convergence
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• v.14 no.8
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• pp.47-56
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• 2016

This study is on the actual analysis of R&D investment effect through DEA in terms of efficiency resulted from forestry sector climate change response R&D project. Namely, it is clarifying the mechanism of the scientific, technological, social performance result and output, depending on research development cost, employment size as same input. Also, it is in-depth analysis on which performance operates more efficiently in any detailed business. With the study result, we seek political implications to enhance investment effect and core element to consider R&D business project in the future.

• The Journal of Korean Medicine
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• v.37 no.4
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• pp.36-44
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• 2016

Objectives: Granulocyte-colony-stimulating factor (G-CSF) mobilized bone marrow (BM)-derived hematopoietic stem cells could contribute to improvement of liver function. In addition, liver fibrosis can reportedly be prevented by the Rg 1 component of red ginseng. This study investigated the combined effect of G-CSF and red ginseng on decompensated liver cirrhosis. Methods: Four patients with decompensated liver cirrhosis were injected with G-CSF to proliferate BM stem cells for 4 days ($5{\mu}g/kg$ bid subcutaneously) and followed-up for 3 months. The patients also received red ginseng for 4 days (2 tablets tid per os). We analyzed Child-Pugh scores, Model for End-Stage Liver Disease (MELD) scores and cirrhotic complications. Results: All patients showed marked increases in White blood cell (WBC) and CD34+ cells in the peripheral blood, with a peak time of 4 days after G-CSF injection. Spleen size also increased after G-CSF injection, but not severely. At end of the study, 2 patients showed improvement in Child-Pugh scores, hepatic encephalopathy, and refractory ascites. During the clinical trial period, none of the 4 patients showed any other adverse events or deterioration of liver function. Conclusions: We conclude that G-CSF/red ginseng combination therapy is relatively effective in improving liver function and major complications of decompensated liver cirrhosis without adverse effects. Further clinical trials are warranted to assess the clinical effects of G-CSF for decompensated liver cirrhosis.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.9 no.5
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• pp.648-658
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• 1998

In this paper, the effect of the gap in the ground plane on the electromagnetic interference (EMI) is analyzed quantitatively. Because of a lot of advantages compared to other numerical techniques, the FDTD (finite difference time domain) is applied to the EMI effect modeling. The analyzed model is the simplified PCB (printed circuit board) which has a microstrip and ground plane. The inductance induced by the gap is modeled and calculated by gridding the whole PCB based on the FDTD algorithm. When external cables are attached to the PCB, the common-mode current is induced along the attached cable and the resulting electric field strength is calculated and presented along with the FCC and CISPR EMI limits. The results show that the radiated field strength highly depends on the size of the ground plane gap. The numerical simulation results can be used as a reference in the practical PCB design with the ground plane gap.

• Korean Journal of Medicinal Crop Science
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• v.20 no.6
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• pp.415-420
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• 2012

In order to evaluate the effect of seed weight on different aspect of safflower (Carthamus tinctorius L.) seed germination and growth characteristics. Quantity of sinapine leaked from seed was greater as the viability of seeds was dropped by the time elapsed of seed aging model and long storage condition in safflower (Carthamus tinctorius L.). The cultivar of safflower was Jin-Sun and the seeds that are separated to three different weights of small, middle, and large were used in this experiment. Large seeds revealed the highest germination percent, coleoptiles fresh weight, coleoptiles dry weight, radicle fresh weight and 1000 seed weights than other seed weight. Seed weight had little effect on yield while seed number exerted a positive influence. Interestingly, yield per plant and its major components, number of capsules and capsule weights, revealed a negligible relationship with oil content.

• Parasites, Hosts and Diseases
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• v.57 no.1
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• pp.1-8
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• 2019

There is no effective treatment modality available against different forms of leishmaniasis. Therefore, the aim of this study was to improve the penetration and efficacy of selenium and glucantime coupled with niosomes and compared them with their simple forms alone on in vitro susceptibility assays. In this study, the niosomal formulations of selenium and in combination with glucantime were prepared. The size and morphology of the niosomal formulations were characterized and the effectivity of the new formulation was also evaluated using in vitro MTT assay, intra-macrophage model, and gene expression profile. From the results obtained, no cytotoxicity effect was observed for niosomal and simple forms of drugs, as alone or in combination. Niosomal formulations of the drugs significantly showed more inhibitory effects ($P{\leq}0.001$) than the simple drugs when the selectivity index was considered. The gene expression levels of Interleukin (IL-10) significantly decreased, while the level of IL-12 and metacaspase significantly increased ($P{\leq}0.001$). The results of the present study showed that selenium plus glucantime niosome possess a potent anti-leishmanial effect and enhanced their lethal activity as evidenced by the in vitro experiments.

• Journal of the Korea Convergence Society
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• v.10 no.10
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• pp.197-205
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• 2019

The purpose of this research was examining the effects of problem-based learning strategies(PBL) on problem solving skill conducted in Korea, using meta-analysis technique. This meta-analysis reviewed the results of 41 studies published between 1998 and 2017 in Korea. The overall weighted mean effect size value was .753 with .064 standard error which was calculated by random effects model. PBL strategies have been found to be more effective in mathematics course (d=.922), art course (d=.916), practical art course (d=.827), E-PBL (d=.791) and middle school level (d=.972). As PBL exhibit a substantial effect on students' problem solving skill, it is recommended that teachers should learn how to implement these strategies in their lesson. PBL is expected to contribute to the improvement of teaching methods as the learning environment changes during the 4th Industrial Revolution.

• 한국사회정책
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• v.19 no.3
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• pp.215-245
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• 2012

The purpose of this study is to examine pathways of factors that influence job satisfaction for full-time and part-time married female employees with children of 18 or under and to compare path coefficients for two groups. Simultaneously analyzing multiple populations, we found that the path model was appropriate for both groups with significant differences in path coefficients. Income, workplace size, husband's support for wife's work, and work-to-family conflict had direct effects on job satisfaction for both groups whereas health had a direct effect only among full-time workers. Family-to-work conflict had an indirect effect for both types of workers, while health had an indirect effect among full-time employees only, and income and having children under school age among part-time employees only. The results indicate that differentiated approaches to increase job satisfaction for full- and part-time employees are needed.

• The Journal of Advanced Prosthodontics
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• v.15 no.4
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• pp.171-178
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• 2023

PURPOSE. The purpose of this study was to determine the effect of the connector configuration on the fracture load in conventional and translucent zirconia of three-unit fixed dental prostheses (FDPs). MATERIALS AND METHODS. Six different three-unit FDPs were prepared (n = 6) from three types of zirconia (3Y-TZP (Katana ML^®), 4Y-TZP (Katana STML^®), and 5Y-TZP (Katana UTML^®)) in combination with two connector configurations (4 × 2.25, 3 × 3 mm). The CoCr master models were scanned, and the FDPs were designed and fabricated using CAD-CAM. The FDPs were cemented on the metal model and then loaded with a UTM at a crosshead speed of 1 mm/min until failure. Two-way ANOVA and Tukey's test were used for statistical analysis (α = .05). RESULTS. Fracture loads of 3Y-TZP (2740.6 ± 469.2 and 2718.7 ± 339.0 N for size 4 × 2.25 mm and 3 × 3 mm, respectively) were significantly higher than those of 4Y-TZP (1868.3 ± 281.6 and 1663.6 ± 372.7 N, respectively) and 5Y-TZP (1588.0 ± 255.0 and 1559.1 ± 110.0 N, respectively) (P < .05). No significant difference was found between fracture loads of 4Y-TZP and 5Y-TZP (P > .05). The connector configuration within 9 mm² was found to have no effect on the fracture loads on all three types of zirconia (P > .05). CONCLUSION. Fracture loads of three-unit FDPs were affected by the type of zirconia. The fracture loads of conventional zirconia were higher than those of translucent zirconia. However, it was not affected by the connector configuration when the connector had a cross-sectional area of 9 mm².

• Korean Journal of Social Welfare Studies
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• v.40 no.2
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• pp.253-283
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• 2009

This study examined empirically the effect mechanism of labor market structure on access to social insurance. Data were derived from the second wave of Korea Welfare Panel Study in 2007 with a sub-sample of 3,790 of wage workers. Path analysis and structural equation model were used to analyze the effect mechanism. Findings confirmed the inequality of labor market by revealing high causal relationships among occupations and jobs, size of the firm, employment forms, and income. The results suggest that access to social insurance depends on the structural interaction of labor market rather than on the individual worker's trait. Small enterprises and non-standard employment were indicated as the main element explaining the unequal access to social insurance. Finally this study identified women's experience of intensive inequalities in the labor market status and access to social insurance.