• Title/Summary/Keyword: size dependent effect

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Inhibitory Effect of Salvia miltiorrhiza Extract on Growth of Some Cancer Cells (단삼(Salvia Miltiorrhiza) 추출물의 암세포 증식 억제 효과에 관한 연구)

  • 정국찬;이지영;김동청;서성옥;황우익
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.29 no.4
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    • pp.726-731
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    • 2000
  • This study was performed to evaluate the antitumor activities of water and ethanol (EtOH) extract of Salvia miltiorrhiza in vitro and in vivo. The proliferation of the human hepatoma (HepG2), rectum cancer (HRT-18) and colon cancer (HT-29) cells was inhibited by administration of extracts in a dose-dependent manner. Particularly, EtOH extract inhibited proliferation of the cells more effectively than water extract did. The morphology of cells induced by EtOH extract was characterized by reduction of cell size and deformatin. Oral administration of the EtOH extract (3 mg/head) to tumor-bearing mice inhibited the tumor (sarcoma-180) growth by 35% and prolonged their survival rate by 61%. The EtOH extract was shown to be nontoxic at 37.5% mg/head/day on the acute toxicity test. These studies suggest that the EtOH extract of Salvia miltiorrhiza may have antitumor activity in vitro and in vivo.

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Magnetic Properties of Nanocrystalline CoW Thin Film Alloys Electrodeposited from Citrate Baths

  • Park, Doek-Yong;Ko, Jang-Myoun
    • Journal of the Korean Electrochemical Society
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    • v.6 no.4
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    • pp.236-241
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    • 2003
  • Magnetic CoW thin film alloys were electrodeposited from citrate baths to investigate the resulting microstructure and magnetic properties. Deposit tungsten (W) content in the films electrodeposited at $70^{\circ}C$ were independent of current density, while coercivity decreased from hard $(H_{c,//}\~150\;Oe\;and\;H_{c.{\bot}}\;\~240\;Oe)$ to soft magnetic properties $(H_{c,//}\~20\;Oe\;and\;H_{c.{\bot}}\;\~30\;Oe)$ with increasing current densities from $10\;to\;100mA{\cdot}cm^2$, with deposit W content $(\~40\%)$ relatively unaffected by the applied current density. X-ray diffraction analysis indicated that hcp $Co_3W$ phases [(200), (201) and (220) planes] in the CoW films electrodeposited at $70^{\circ}C\;and\;10mA{\cdot}cm^{-2}$ were dominant, whereas amorphous CoW phases with small amount of hcp $Co_3W$ [(002) planes] were dominant with deposition at $70^{\circ}C\;and\;100mA{\cdot}cm^{-2}$. At intermediate current densities $(25\;and\;50mA{\cdot}cm^{-2}),\;hop\;Co_3W$ phases [(200), (002), (201) and (220)] were observed. The average grain size was measured to be 30 nm from Sheller formula. It is suggested that the change of the deposit coercivities in the CoW thin films electrodeposited at $70^{\circ}C$ is attributed to the change of microstructures with varying the current density. Nanostructured $Co_3W/amorphous-CoW$ multilayers were fabricated by alternating current density between 10 and $100 mA{\cdot}cm^{-2}$, varying the individual layer thickness. The magnetic properties of $Co_3W/amorphous-CoW$ multilayers were strongly dependent on the thickness of the alternating hard and soft magnetic thin films. The nanostructured $Co_3W/amorphous-CoW$ multilayers exhibited a shift from low to high coercivities suggesting a strong coupling effect.

Milling Effects of $Y_2BaCuO_5$ Precursor Powder with $CeO_2$ Addition on the Critical Current Density of Liquid Infiltration Growth Processed $YBa_2Cu_3O_{7-y}$ Bulk Superconductors (액상 침투 성장법으로 제조된 $YBa_2Cu_3O_{7-y}$ 벌크 초전도체의 임계전류밀도에 대한 $CeO_2$ 첨가된 $Y_2BaCuO_5$ 분말의 밀링 효과)

  • Asif, Mahmood;Jun, Byung-Hyuk;Kim, Chan-Joong
    • Progress in Superconductivity
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    • v.12 no.1
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    • pp.6-11
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    • 2010
  • The milling effects of a precursor $Y_2BaCuO_5$ (Y211) powder having 1 wt.% $CeO_2$ on the microstructure and critical current density ($J_c$) of liquid infiltration growth (LIG) processed $YBa_2Cu_3O_{7-y}$ (Y-123) bulk superconductors were investigated. The microstructure analysis revealed that the Y211 size in the final Y-123 products decreased with increasing the milling time and a relatively high density and uniform distribution of Y211 inclusions were observed in the sample prepared using 8 h milled powder. However, the unexpected Y211 particles coarsening was observed from the 4 h milled sample which was further increased for 10 h milled sample. Critical current density ($J_c$) of the LIG processed Y-123 bulk superconductors was found to be dependent on the milling time of the Y211 precursor powder. The $J_c$ increased with the increase of milling time and reached up to a maximum at 8 h in the self field while 10 h milled sample showed lower $J_c$ at the same field which might be due to the exaggerated growth and non-uniform distribution of Y211 particles.

Effect of welding variables on the crack arrest toughness of thick steel plate (선급 극후물재의 취성균열 전파 정지 인성에 미치는 용접변수의 영향)

  • Ryu, Kang-Mook;An, Gyu-Baek;Kim, Tae-Su;Lee, Tae-Yeung;Lee, Jong-Sub
    • Proceedings of the KWS Conference
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    • 2009.11a
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    • pp.103-103
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    • 2009
  • As the size of containership increased over 14,000TEU, thick steel plate with high strength has been used. The plate thickness increased over 70mm and yield strength of the steel plate was around $47kg_f/mm^2$. Many researchers reported that the thick welded plate has low crack arrest toughness. They noticed the crack arrest ability is dependent on the plate thickness. In other words, brittle crack propagates straightly along the welded line and make abrupt fracture in the thick plate which causes low $K_{ca}$. In this study, the other factors, especially welding heat input, to cause low crack arrest toughness was investigated for thick steel plate welds. EH grade steel plates were used in this study and 50 to 80 thick plates were tested to confirm thickness sensitivity. Electro gas welding (EGW) and flux cored arc welding (FCAW) were adopted to prepare the welded joints. Temperature gradient ESSO test was performed to measure $K_{ca}$ values with the variation of welding variables. As a result of this study, regardless of plate thickness, welding heat input to cause welding residual stress around crack path is a key factor to control the brittle crack propagation in welded joints.

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Estimating the productive efficienct of distant-water longline vessels in Pacific Ocean using a Stochastic Frontier Approach (SFA를 이용한 태평양 원양연승어업의 어선별 생산효율성 분석)

  • CHO, Heon-Ju;KIM, Doo Nam;KIM, Do Hoon;LEE, Sung Il;KWON, Youjung;KU, Jeong Eun
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.53 no.4
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    • pp.357-362
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    • 2017
  • The purpose of this study is to analyze the efficiency of distant-water longline fishing vessels in the Pacific Ocean and the gap in efficiencies among individual vessels. In order to estimate the efficiency, the dependent variable is set as an amount of catch and independent variables include number of crew, number of hooks, number of vessel size, and vessels engine power associated with fishing activities of distant water longline fisheries. Analytical result was shown as follows: first, the average efficiency of distant-water longline fishing vessels in the Pacific Ocean was found to be 94%. Second, the number of hooks were found to be statistically significant in each input variable and the appropriate control of the number of hooks would be expected to have a positive effect on the efficiency. Third, the relationship between the age of a vessel and the efficiency was not found statistically.

An Analysis of Thermal Stress and Angular Distortion in Bead-on-Plate Welding Incorporating Constrained Boundary Conditions (판재의 비드 용접에서 구속경계조건을 적용한 열응력 및 각변형 해석)

  • 배강열;최태완
    • Journal of Welding and Joining
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    • v.17 no.1
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    • pp.104-115
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    • 1999
  • There have been many studies on the two dimensional thermo-elasto-plastic analysis in welding process, mostly from viewpoint of residual stresses. In this study, the temperature distribution, transient thermal stress, and angular distortion during bead-on-plate gas metal arc welding of rectangular plates were analyzed by using the finite element method. A nonlinear heat transfer analysis was first performed by taking account of the temperature-dependent material properties and convection heat losses on the surface. This was followed by a thermo-elasto-plastic stresses and distortion analysis that incorporates the constrained boundary condition of the two dimensional solution domain to get the three dimensional size effect of the plate. The constrained boundary conditions adopted in this study were the constant displacement condition over the whole two dimensional section for axial movement in the welding direction, and the force boundary condition for rotational movementof the domain around the axis of the welding direction. It could be revealed that the theoretical predictions of the angular distortion have an improved agreement with the experimentally obtained data presented in the previous study.

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Liquidity Determinants of Private Hospitals in Korea (민간병원의 유동성 관련요인 분석)

  • Choi, Man-Kyu;Lee, Yun-Seok;Lee, Yoon-Hyeon
    • Health Policy and Management
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    • v.12 no.4
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    • pp.1-17
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    • 2002
  • This study was attempted to identify the liquidity trends and determinants of private hospitals in Korea different. Data used in this study were collected from 98 hospitals with complete general data of present conditions as well as financial statements(balance sheets, income statements). They were chosen from hospitals that passed the standardization audit undertaken by the Korean Hospital Association from 1996 to 2000 for the purpose of accrediting training hospitals. The dependent variables in this study were used current ration and quick ratio as a proxy indicator for liquidity. The independent variables were ownership type, hospital type, location, bed size, period of establishment, short-term liabilities to total assets, long-term liabilities to total assets, borrowings to total assets, fixed asset ration, net profit to total assets, operating margin to gross revenue, growth rate of net worth to total assets, total asset turnover, and business risk(volatility of profit). The major findings of this study were as follows. Trends of liquidity(current ratio, quick ratio) had been continuously decreased. Especially, There were very distinct decreasing trends of personal hospitals and less than 300beds, which weakened liquidity. The factors had significant effect on current ratio were short-term debt to total assets(-), fixed asset ratio(-), business risk(+). High short-term debt to total assets, high fixed asset ratio and high business risk significantly decreased in liquidity. The factors that significantly affected on quick ratio were short-term debt to total assets(-), borrowings to total assets(+), fixed asset ratio(-), business risk(+).

Synthetic Characteristics of Porous Polymeric Catalyst Support (다공성 고분자촉매 담체의 제조 특성)

  • Kang, Hee-Suk;Lee, Han-Soo;Chung, Hongsuk;Ahn, Do-Hee;Son, Soon-Hwan;Chung, Yang Geun;Song, Myung-Jae
    • Applied Chemistry for Engineering
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    • v.7 no.4
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    • pp.715-725
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    • 1996
  • This study represents the synthetic characteristics of styrene-DVB copolymer which is used as a catalyst support for the removal of tritium in CANDU. To evaluate the effect of solvent on the styrene-DVB polymeric support, the solvating power dependent on various kinds and composition of solvents was calculated. In order to synthesize the macroreticular type polymer bead, the following conditions are needed; solvating power should be higher than 1 for 20% of crosslinkage and higher than 3 for 40% of crosslinkage. Stabilization of organic monomers at about $40^{\circ}C$ for more than 2 hours is prerequisite. Removal of solvent prior to drying is preferred for the post-treatment of the bead. The polymer particle size was increased by lowering concentration of surfactant and stirring speed.

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The Effect of SiO2 on the Microstructure and Electrical Properties of BaTiO3 PTC Thermistor (BaTiO3 PTC 써미스터의 미세구조 및 전기적 특성에 대한 SiO2 영향)

  • Chun, Myoung-Pyo
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.26 no.1
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    • pp.22-26
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    • 2013
  • PTCR ceramics of $(Ba_{0.998}Sm_{0.002})TiO_3+0.001MnCO_3+xSiO_2$ (x=1, 2, 3, 4, 5, 6 mol%) were fabricated by solid state method. Disk samples of diameter 5 mm and thickness about 1mm were sintered at $1,290^{\circ}C$ for 2 h in reduced atmosphere of $5%H_2-95%N_2$ followed by re-oxidation at $600^{\circ}C$ for 30 min. in $20%O_2-80%N_2$.and their microstructures and electrical properties were investigated with SEM and Multimeter. The color of sintered samples was strongly dependent on $SiO_2$ content showing that the color of samples with $SiO_2$ of 1~2 mol% was gray but that of samples with $SiO_2$ of 4~6 mol% was changed from gray to blue, which seems to be related with the reduction of samples due to the oxygen vacancies created during the sintering in reduced atmosphere. $SiO_2$ content had a great influence on the microstructure and the electrical properties. With increasing $SiO_2$ content, the grain size of samples increased and the resistivity as well as the resistivity jump ($R_{285}/R_{min}$) decreased, which is considered to be attributed to the resistivity change at grain interior and grain boundary due to the fast mass transfer through $SiO_2$ liquide phase during the sintering. Samples with 2 mol% $SiO_2$ has the resistivity of $202{\Omega}cm$ and the resistivity jump of 3.28. It is expected that $SiO_2$ doped $BaTiO_3$ based PTC ceramics can be used for multilayered PTC thermistor due to the resistance to the sintering in reduced atmosphere.

Time dependent behavior of piled raft foundation in clayey soil

  • Fattah, Mohammed Y.;Al-Mosawi, Mosa J.;Al-Zayadi, Abbas A.O.
    • Geomechanics and Engineering
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    • v.5 no.1
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    • pp.17-36
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    • 2013
  • Settlement of the piled raft can be estimated even after years of completing the construction of any structure over the foundation. This study is devoted to carry out numerical analysis by the finite element method of the consolidation settlement of piled rafts over clayey soils and detecting the dissipation of excess pore water pressure and its effect on bearing capacity of piled raft foundations. The ABAQUS computer program is used as a finite element tool and the soil is represented by the modified Drucker-Prager/cap model. Five different configurations of pile groups are simulated in the finite element analysis. It was found that the settlement beneath the piled raft foundation resulted from the dissipation of excess pore water pressure considerably affects the final settlement of the foundation, and enough attention should be paid to settlement variation with time. The settlement behavior of unpiled raft shows bowl shaped settlement profile with maximum at the center. The degree of curvature of the raft under vertical load increases with the decrease of the raft thickness. For the same vertical load, the differential settlement of raft of ($10{\times}10m$) size decreases by more than 90% when the raft thickness increased from 0.75 m to 1.5 m. The average load carried by piles depends on the number of piles in the group. The groups of ($2{\times}1$, $3{\times}1$, $2{\times}2$, $3{\times}2$, and $3{\times}3$) piles were found to carry about 24%, 32%, 42%, 58%, and 79% of the total vertical load. The distribution of load between piles becomes more uniform with the increase of raft thickness.