• 대한상한금궤의학회지
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• 제6권1호
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• pp.37-54
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• 2014

Objective : The purpose of this paper is to report the effect of three different herb medication based on Shanghanlun(傷寒論) six differential diagnostic system. Methods : According to six differential diagnostic system based on Shanghanlun provisions, they were diagnosed with Taiyang-byung(大陽病), Yangmyung-byung(陽明病), Gwoleum-byung(厥陰病). They took different herb medications more than 6weeks according to their diagnosis. This paper evaluated the results of treatment by pregnancy test result with improvement of symptoms. Results : The symptoms of three patients were improved and became pregnant. Conclusions : This case study suggests that herb medication based on Shanghanlun(傷寒論) six differential diagnostic system have effectiveness on unexplained infertility. And we need to have a diversified and new perspectives in women's position about pregnancy with this system.

• 대한상한금궤의학회지
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• 제7권1호
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• pp.133-147
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• 2015

Objective : The purpose of this paper is to report the effect of Danggwihweyeokgaohsuyu-saenggang-tang(DHGOST) on primary dysmenorrhea from the disease pattern identification diagnostic system based on Shanghanlun provisions. Methods : According to a disease pattern identification diagnostic system based on Shanghanlun provisions, the patient was diagnosed with 'Reverting Yin Disease'. She took DHGOST for 75 days. This paper evaluated the results of treatment by Measure of Menstrual Pain(MMP) and Menstrual Symptom Severity List(MMSL) Results : The MMP score was declined from 8.3 to 3.5. And the MMSL score was declined from 46 to 38. Conclusions : This case study suggests that DHGOST has effectiveness on primary dysmenorrhea who is diagnosed with 'Reverting Yin Disease'.

• 대한상한금궤의학회지
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• 제8권1호
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• pp.109-119
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• 2016

Objective : The purpose of this paper is to report the effect of Daehamhyung-tang(DHHT) on tinnitus with panic disorder from the disease pattern identification diagnostic system based on Shanghanlun provisions. Methods : According to a disease pattern identification diagnostic system based on Shanghanlun provisions, the patient was diagnosed with 'Taeyang-byung Gyeolhyung'. He took DHHT for 82 days. This paper evaluated the results of treatment on tinnitus by Tinnitus Handicap Inventory(THI) and Verbal Numercial Rating Scale(VNRS). To assess the mental state of anxiety, this paper used Hamilton Anxiety Rating Scale(HAM-A) Results : The THI score was declined from 58 to 6 And the VNRS score was declined from 6 to 1. HAM-A score was declined from 28 to 3. Conclusions : This case study suggests that DHHT has effectiveness on a patient suffers from tinnitus with panic disorder and diagnosed with 'Taeyang-byung Gyeolhyung'.

• 사상체질의학회지
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• 제19권1호
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• pp.19-28
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• 2007

1. Objectvies The study is purposed to find the role of the six-channels of shanghan(傷寒六經) on the relation between ${\ulcorner}$Dongyisusaebowon(東醫壽世保元)${\lrcorner}$ and ${\ulcorner}$Shanghanlun(傷寒論)${\lrcorner}$ 2. Methods The study is compared ${\ulcorner}$Euiwonleun(醫源論)${\lrcorner}$ with the process of study on the ${\ulcorner}$Shanghanlun(傷寒論)${\lrcorner}$, origin and theorys of the Shanghan six-channels(傷寒六經). 3. Results and Conclusions Just as Dong-mu fully understood the concepts of ${\ulcorner}$Shanghanlun(傷寒論)${\lrcorner}$ through the six of Shanghan(傷寒六經) proposed by Chu-gueng(朱肱), the ideas of Differential Diagnostic System(辨證體系) of ${\ulcorner}$Shanghanlun(傷寒論)${\lrcorner}$ had much influence on ${\ulcorner}$Dongyisusaebowon(東醫壽世保元)${\lrcorner}$. Therefore a new medical theory could be born.

• 동의생리병리학회지
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• 제30권1호
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• pp.1-6
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• 2016

In recent years, there were frequent exogenous contagious diseases in Eastasia like SARS(severe acute respiratory syndrome), Avian influenza, Swine influenza, MERS etc. But there are various interpretations about their pathological differentiations and lead to controversy to diagnosis and medicinal use. So there needs universal and consistent understanding methods. Several conclusions are obtained from the research on differentiation theories of various epidemic diseases. Essential elements of differential diagnostic system are pathogen, characters and matters of disease and loci, especially three yin and three yang has close affinity with constitutional features or body shape. Binding these 3 categories, an integrated differentiation 3 dimensional coordinates are made. Out of these, each elements of 3 pathogen-axial lines are related with names of exogenous disease, and those of 3 feature-axial lines are related with 8 principal patterns. And those of 3 locus-axial lines implicating therapeutic method are related with steps and location of exterior and interior, 3 yin 3 yang, Defense, Qi, Nutrient and Blood, five viscera and six bowels and tissues. Additionally, 3 lines of each axis consist of factors which have their own affinity each other, so classification of pathogen, feature, locus of disease has layered interconnectedness. This classification system is included in constitutional features of individual patient. Afterwards, these cognitive structure can be used as a general theory guiding method of therapy, prevention and aftercure healthcare.

• 한국방사선학회논문지
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• 제10권6호
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• pp.443-450
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• 2016

본 연구는 복부 전산화단층촬영 영상을 이용하여 지방간환자의 영상을 질감특징분석과 ROC curve 분석을 하였으며, 컴퓨터보조진단시스템의 구현을 위한 실험적인 선형 연구로서 전산화단층촬영 영상에서 지방간의 객관적이고 신뢰성 있는 진단 정보를 의사에게 제공하고자 하였다. 실험은 정상 및 지방간 복부 전산화단층촬영 영상을 실험영상으로 하여 설정된 구역에 대한 wavelet 변환을 거쳐 질감의 특징값을 나타내는 6가지 파라미터로 통계적 분석 결과를 나타내었다. 그 결과 엔트로피, 평균밝기, 왜곡도는 90% 이상의 비교적 높은 인식률을 보였고, 대조도, 평탄도, 균일도는 약 70% 정도로 비교적 낮은 인식률을 나타내었다. ROC curve를 이용한 분석에서 6가지의 파라미터 모두 0.900(p=0.0001)이상을 나타내어 질환인식에 의미가 있는 결과를 나타내었다. 또한 6가지 파라미터에서 질환 예측을 위한 cut-off 값을 결정하였다. 이러한 결과는 향후 복부 전산화단층촬영 영상에서 질환 자동검출 및 최종진단의 예비 진단 자료로서 적용 가능할 것이다.

• 대한방사선기술학회지:방사선기술과학
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• 제46권1호
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• pp.29-36
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• 2023

To have highly reliable diagnostic performance of it, this study comparatively analyzed spatial resolution of SPECT images and interrelationship depending on the changes of system uniformity of ga㎜a camera through phantom analysis. This study chose 6 kinds of results from quality control (uniformity) of triple head SPECT scanner operated in an university hospital in Seoul for six months. Then, study measured spatial resolutions (FWHM) of the images restructured by injecting radiopharmaceuticals to Jaszczak phantom, and doing SPECT scanning under the same conditions as clinical ones using the analytical program (image J). Quality controls performed by the experimental institution showed that differential uniformity of UFOV ranged from 2.76% to 7.61% (4.46±2.07), and integral uniformity of UFOV ranged from 1.98% to 5.42% (3.01±1.43). Meanwhile, Quantitative analysis evaluations of phantom images depending on the changes of uniformity of SPECT scanner detector showed that as the uniformity values of UFOV and CFOV decreased, FWHM values of phantom images decreased from 8.5 ㎜ to 5.8 ㎜. That is, it was quantitatively identified that the higher uniformity of detector is, the better spatial resolution of images gets (P<0.05). It is very important to perform continuous and consistent quality control of the nuclear medicinal system, and users should be clearly conscious of it.

• Investigative Magnetic Resonance Imaging
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• 제25권4호
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• pp.313-322
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• 2021

Purpose: To find diagnostic image features, to compare diagnostic performance of multiphase CT versus gadoxetic acid disodium-enhanced MRI (GAD-MRI), and to evaluate the impact of analyzing Liver Imaging Reporting and Data System (LI-RADS) imaging features, for distinguishing combined hepatocellular-cholangiocarcinoma (CHC) from hepatocellular carcinoma (HCC). Materials and Methods: Ninety-six patients with pathologically proven CHC (n = 48) or HCC (n = 48), diagnosed June 2008 to May 2018 were retrospectively analyzed in random order by three radiologists with different experience levels. In the first analysis, the readers independently determined the probability of CHC based on their own knowledge and experiences. In the second analysis, they evaluated imaging features defined in LI-RADS 2018. Area under the curve (AUC) values for CHC diagnosis were compared between CT and MRI, and between the first and second analyses. Interobserver agreement was assessed using Cohen's weighted κ values. Results: Targetoid LR-M image features showed better specificities and positive predictive values (PPV) than the others. Among them, rim arterial phase hyperenhancement had the highest specificity and PPV. Average sensitivity, specificity, and AUC values were higher for MRI than for CT in both the first (P = 0.008, 0.005, 0.002, respectively) and second (P = 0.017, 0.026, 0.036) analyses. Interobserver agreements were higher for MRI in both analyses (κ = 0.307 for CT, κ = 0.332 for MRI in the first analysis; κ = 0.467 for CT, κ = 0.531 for MRI in the second analysis), with greater agreement in the second analysis for both CT (P = 0.001) and MRI (P < 0.001). Conclusion: Rim arterial phase hyperenhancement on GAD-MRI can be a good indicator suggesting CHC more than HCC. GAD-MRI may provide greater accuracy than CT for distinguishing CHC from HCC. Interobserver agreement can be improved for both CT and MRI by analyzing LI-RADS imaging features.

• Tuberculosis and Respiratory Diseases
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• 제82권3호
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• pp.234-241
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• 2019

Background: The utility of computed tomography (CT) in the differential diagnosis of patients with chronic obstructive pulmonary disease (COPD) exacerbation remains uncertain. However, due to the low cost associated with CT scan along with the impact of Koreas' health insurance system, there has been a rise in the number of CT scans in the patients with initial diagnosis of COPD exacerbations. Therefore, the utility of CT in the differential diagnosis was investigated to determine whether performing CT scans affect the clinical outcomes of the patients with an initial diagnosis of COPD exacerbation. Methods: This study involved 202 COPD patients hospitalized with an initial diagnosis of COPD exacerbation. We evaluated the change in diagnosis or treatment after performing a CT scan, and compared the clinical outcomes of patient groups with vs. without performing CT (non-CT group vs. CT group). Results: After performing CT, the diagnosis was changed for two (3.0%) while additional diagnoses were made for 27 of the 64 patients (42.1%). However, the treatment changed for only one (1.5%), and six patients (9.3%) received supplementary medication. There were no difference in the median length of hospital stay (8 [6-13] days vs. 8 [6-12] days, p=0.786) and intensive care unit care (14 [10.1%] vs. 11 [16.7%], p=0.236) between the CT and non-CT groups, respectively. These findings remained consistent even after the propensity score matching. Conclusion: Utility of CT in patients with acute COPD exacerbation might not be helpful; therefore, we do not recommend chest CT scan as a routine initial diagnostic tool.

• 한국HCI학회논문지
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• 제2권1호
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• pp.41-47
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• 2007

한정된 주의력 자원을 회복시키기 위한 방법 중 피드백이 효과가 있는 것으로 보고되고 있다. 그러나 피드백의 구체적 내용에 대한 집중력 회복의 연구는 미미하다. 본 연구는 집중력을 회복할 수 있는 감각적 자극 중 정서적 피드백 간의 효과 차이를 분석 하였다. 집중력을 평가하기위한 온라인 실험 시스템을 구축하고 시각, 청각, 촉각 피드백 자극을 제시하여 각각의 감각자극과 집중력 회복의 효과를 분석 하였다. 실험 참여자의 감각 피드백의 선호도에 따른 영향 요인을 알아보기 위하여 실험 후 주관적 설문을 실시하였다. 감각 피드백을 6명의 대학원생에게 일주일에 걸쳐 반복적으로 약200개의 자극을 제시하고 5회 이상 실험을 통하여 얻어진 30회 결과를 분석하였다. 결과적으로 피드백 효과가 집중력 회복에 통계적 유의함을 알 수 있었다.