• Journal of the Korean Geotechnical Society
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• v.30 no.10
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• pp.67-80
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• 2014

The thickness of permafrost in Eastern Siberia is from 200 to 500 meters. The seasonally frozen layer can vary from 0 to 4m depending on ground temperature and its location. The shear wave velocity varies from 80m/s in summer to 1500m/s in winter depending on soil type. When melted, large impedence will occur due to the difference between the shear wave velocity of seasonally frozen soil and that of permafrost layer. Large displacement may occur at the boundary of the melted and the frozen layer, and this phenomenon should be considered in a seismic design. In this research, one-dimensional equivalent linear analyses were performed to investigate the effects of the seasonally frozen layer on ground amplification characteristics. Soil profiles of Yakutsk and Chara in Eastern Siberia were selected from geotechnical reports. 20 recorded ground motions were used to evaluate the effect of input motions. As the thickness of seasonally frozen layer and the difference in the shear wave velocity increases, the amplification is shown to increase. Peat, very soft organic soil widely distributed throughout Eastern Siberia, is shown to cause significant ground motion amplification. It is therefore recommended to account for its influence on propagated motion.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.45 no.3
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• pp.190-194
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• 2000

Double cropping is important for increase of farm income and rate of arable land utilization. This study was carried out to obtain information for optimum plant density of the second crop in a double cropping system. A waxy corn hybrid, Chalok #2, was sown on July 10 at the first corn cropping site. Growth characteristics and yield response of fresh waxy corn were examined under different planting densities, which were 55.5, 66.6, 83.3, and 111.1 thousands plants ${ha}^{-1}$. Plant height was higher under high planting density than low planting density and 154cm at the 55.5 thousand plants ${ha}^{-1}$, and 168cm at the 111.1 thousand plant ${ha}^{-1}$. It showed same trends in ear height and gravity center height. But planting density did not affect root lodging and silking date. At the silking stage, stalk and leaf dry matter weight and leaf area index (LAI) were increased significantly with increasing planting density, Filled ear lengtg was shortened significantly under the hi임est planting density (111.1 thousand plants ${ha}^{-1}$), while ear length and ear diameter were no differences among planting densities. The number of marketable ears increased with increasing planting density, but husked fresh ear weight was the highest at 83.3 thousand plants ${ha}^{-1}$ with 11.2MT ${ha}^{-1}$and optimum planting density was estimated as about 80 thousand plants ${ha}^{-1}$.

• Journal of the Korean Geotechnical Society
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• v.18 no.1
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• pp.91-99
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• 2002

In this study, a new methodology for the assessment of liquefaction potential is proposed. Since there is no data on the liquefaction damage in Korea, the dynamic behavior of fully saturated soils is characterized through laboratory dynamic tests. There are two experimental parameters related to the soil liquefaction resistance characteristics : the one is the index of disturbance determined by $G/G_{max}$ curve and the other is a plastic shear strain trajectory evaluated from stress-strain curve. The proposed methodology takes advantage of the site response analysis based on real earthquake records to determine the driving effect of earthquake. In the evaluation of liquefaction resistance characteristics, it is verified experimentally that the magnitude of cyclic shear stress has no influence on the critical value of plastic shear strain trajectory at which the initial liquefaction occurs. Cyclic triaxial tests under the conditions of various cyclic stress ratios and torsional shear tests are carried out far the purpose of verification. Through this study, the critical value at the initial liquefaction is found unique regardless of the cyclic stress ratio. It is also f3und that liquefaction resistance curve drawn with disturbance and plastic shear strain trajectory can simulate the behavior of fully saturated soils under dynamic loads.

• Journal of environmental and Sanitary engineering
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• v.18 no.3 s.49
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• pp.100-109
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• 2003

Recently, Indoor air quality(IAQ) in workplace, residential environments and schools has been concern of people, scientists and related the public. And so in Seoul has recognized the healthy effect related to IAQ in schools. Therefore, the objective of this study reported in this article were to measure and compare the perception of IAQ of selected air pollutants at three different schools in Seoul. We performed a questionnaire survey of 400 students about their awareness for the importance of IAQ in our school. And we measured the IAQ of 3 schools considering as site region, construction year and studying level. The indoor air pollutants and parameters such as temperature, relative humidity, respirable particulate matter(PM10), formaldehyde(HCHO), total bacteria counts(TBC), carbon dioxide(CO$_2$), and noise were monitored in indoors. In results, all most response of occupant has recognized the awareness of IAQ at schools. The PMIO, TBC and Noise level of all schools were higher than the standard of the public 150 ${mu}$g/m$^3$ and 500CFU/m$^3$, the level formaldehyde(HCHO) was below 0.1 ppm of the healthy guideline of Korea And the concentration of CO$_2$ were investigated below 1,000 ppm of the standard implying ventilation in 2 schools except for 1 school(c school). Finally, the control of most important pollutants of IAQ in school were PM10, TBC and Noise. Therefore, it can be concluded that the indoor air quality of selected 3 schools studied was perceived as acceptable, it is recommended that the government related IAQ was suggested the guideline and control of IAQ problems in schools, and all member relating school need to be effort to reduce the exposure of sources to undesirable indoor pollutants such as Particlate and Noise.

• The Korean Journal of Physiology and Pharmacology
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• v.17 no.4
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• pp.291-297
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• 2013

Notch1 has been reported to be highly expressed in triple-negative and other subtypes of breast cancer. Mutant p53 (R280K) is overexpressed in MDA-MB-231 triple-negative human breast cancer cells. The present study aimed to determine whether the mutant p53 can be a potent transcriptional activator of the Notch1 in MDA-MB-231 cells, and explore the role of this mutant p53-Notch1 axis in curcumin-induced apoptosis. We found that curcumin treatment resulted in an induction of apoptosis in MDA-MB-231 cells, together with downregulation of Notch1 and its downstream target, Hes1. This reduction in Notch1 expression was determined to be due to the decreased activity of endogenous mutant p53. We confirmed the suppressive effect of curcumin on Notch1 transcription by performing a Notch1 promoter-driven reporter assay and identified a putative p53-binding site in the Notch1 promoter by EMSA and chromatin immunoprecipitation analysis. Overexpression of mutant p53 increased Notch1 promoter activity, whereas knockdown of mutant p53 by small interfering RNA suppressed Notch1 expression, leading to the induction of cellular apoptosis. Moreover, curcumin-induced apoptosis was further enhanced by the knockdown of Notch1 or mutant p53, but it was decreased by the overexpression of active Notch1. Taken together, our results demonstrate, for the first time, that Notch1 is a transcriptional target of mutant p53 in breast cancer cells and suggest that the targeting of mutant p53 and/or Notch1 may be combined with a chemotherapeutic strategy to improve the response of breast cancer cells to curcumin.

• Journal of Periodontal and Implant Science
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• v.33 no.1
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• pp.13-26
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• 2003

Periodontal regeneration therapy with bone-substituting materials has gained favorable clinical efficacy by enhancing osseous regeneration in periodontal bony defect. As bone-substituting materials, bone powder, calcium phosphate ceramic, modified forms of hydroxyapatite, and hard tissue replacement polymer have demonstrated their periodontal bony regenerative potency. Bone-substituting materials should fulfill several requirements such as biocompatibility, osteogenecity, malleability, biodegradability. The purpose of this study was to investigate biocompatibility, osteo-conduction capacity and biodegradability of $Na_2O$, $K_2O$ added calcium metaphosphate(CMP). Beta CMP was obtained by thermal treatment of anhydrous $Ca_2(H_2PO_4)_2$. $Na_2O$ and $K_2O$ were added to CMP. The change of weight of pure CMP, $Na_2O$-CMP, and $K_2O$-CMP in Tris-buffer solution and simulated body fluid for 30 days was measured. Twenty four Newzealand white rabbits were used in negative control, positive control(Bio-Oss), pure CMP group, 5% $Na_2$-CMP group, 10% $Na_2O$-CMP goup, and 5% $K_2O$-CMP group. In each group, graft materials were placed in right and left parietal bone defects(diameter 10mm) of rabbit. The animals were sacrificed at 3 months and 6 months after implantation of the graft materials. Degree of biodegradability of $K_2O$ or $Na_2O$ added CMP was greater than that of pure CMP in experimental condition. All experimental sites were healed with no clinical evidence of inflammatory response to all CMP implants. Histologic observations revealed that all CMP grafts were very biocompatible and osseous conductive, and that in $K_2O$-CMP or $Na_2O$-CMP implanted sites, there was biodegradable pattern, and that in site of new bone formation, there was no significant difference between all CMP group and DPBB(Bio-Oss) group. From this result, it was suggested that all experimental CMP group graft materials were able to use as an available bone substitution.

• Journal of Korean Tunnelling and Underground Space Association
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• v.22 no.4
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• pp.367-381
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• 2020

This paper presents the seal material mixing ratio of tunnel umbrella arch reinforcement method. Currently, there is no clear standard for the proper gelation time and curing time of the Seal material in Korea, and the quality control is also difficult because it cannot be verified. In response, the ratio of the mixture of the seal material was composed of four types of indoor experiments, and the amount of gelation time and bleed was checked. In addition, a non-cart penetration test confirmed the curing time and compared the ratio of each combination. Further experiments on W/C 120% identified the effect of mixing speed and time on the seal material. A total of three field experiments were conducted based on indoor experiments, and the size and strength of bulb formation were compared by checking the curing time of the specimen and main injection. Comparisons show that the lower W/C, the stronger the strength, the larger the size of the bulb, and the faster the hardening time appears. Based on the results of the gelation time and curing time, it was deemed that the mixing ratio of W/C 120% is most appropriate when applied to the actual site.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.26 no.6
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• pp.439-445
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• 2013

The soil-structure interaction(SSI) effect should be considered to accurately assess the seismic response of structure constructed on soft soil site other than the hard bedrock. Recently, the demand of SSI analysis has increased due to strengthening of the regulatory guidelines of nuclear power plant such as the USNRC SRP 3.7.2. In this study an accuracy and running time of the KIESSI-3D program for large-scale 3D SSI analysis were investigated. The seismic SSI analysis using the KIESSI-3D program was performed for several examples of large-scale three-dimensional soil-structure interaction system. The analysis results were compared with those of the ACS/SASSI program. Good agreements in transfer functions at selected locations showd that KIESSI-3D yields accurate solution for large-scale SSI problem. Moreover, it was found that running speed of the KIESSI-3D for large-scale 3D SSI analysis is much faster than that of the ACS/SASSI about 30~2000 times.

• Korean Business Review
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• v.18 no.1
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• pp.81-108
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• 2005

Recent market environment shows a new relationship between customer and company, which you could not observe in the past. Customers now are used to various benefits through the participation of marketing process. It is no wonder that customers visit company web site, gather a lot of information about the product on the website, and express their satisfaction and opinions about the product. Furthermore, these activities are being made ubiquitously. Despite the fact there are a lot of customer participation in the Internet environment, Customers Participation has been given little attention in the academic literature. This study explores the effect of the properties of Internet infra on customers participation. The implications of this study are as follows. First, by reviewing the literature on the performance and process of customers participation in the marketing activities, this study identifies why customers did not participate in the marketing activities under non-Internet environment. Second, this study identifies the properties of Internet infra influencing customers informative participation. Third, we suggest some managerial strategies for enhancing the performance of a company by customer participation. Consequently, we suggest managerial implications for completely different marketing strategies in response to customers participation in the marketing activities under the digital environment.

• Spatial Information Research
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• v.15 no.3
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• pp.237-249
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• 2007

There are about 22,000 national control points throughout this nation. However, in order to identify the location data of a national control point, a control point result table is needed. And although the control points are important national facilities, due to the fact that these points located at remote areas such as on top of mountains, the facilities are being maintained via on-site inspection without any protections around them. In this research, by taking the locations where the control points are placed into consideration, a specialized RFID tags that can be attached to the national control point's marker has been developed, and CDMA-ready PDA based mobile Web System and national control point control system are developed as well. With help of these systems, control point data can be checked at the seen, and national control point maintenance personnel can find out about maintenance status and keep track of usage record. When these systems are taken into effect, access to the national control point data becomes easy, fast response to the change in data can be possible, and management efficiency will go up. When the Ubiquitous society becomes reality, the importance of location information will be high. Therefore, national control points using above mentioned RFID tags will not only be useful to the control point users and maintenance personnels such as professional land surveyors, but also useful when providing location based services to people, and it will become an important national infrastructure in terms of providing absolute location information.