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Enhanced Recovery after Cancer Surgery using Dokhwaljihwang-tang-gami : A Case Series (독활지황탕가미를 이용한 암 수술 후 조기 회복 : 연속 증례 보고)

  • Jung, Nu-ri;Choi, Yu-jin;Kim, Ki-tae;Shin, Seon-mi;Ko, Heung
    • The Journal of Internal Korean Medicine
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    • v.41 no.2
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    • pp.248-255
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    • 2020
  • Objectives: Fatigue, malnutrition, and weight loss are common complaints after undergoing surgery for cancer. These symptoms can be associated with Yin-Deficiency (陰虛) of Exhaustion syndrome (虛勞). Therefore, this study aimed to determine if it is possible to use Dokhwaljihwang-tang, which originates from Yukmijihwang-tang, for enhanced recovery after cancer surgery. Methods: After cancer surgery, Dokhwaljihwang-tang-gami was administered three times a day, in 80-120 ml doses at a time. Results: In four cases of gastric, colorectal, and thyroid cancer, enhanced recovery was achieved using Dokhwaljihwang-tang-gami to treat general weakness, fatigue, and pain in the surgical site after cancer surgery. Conclusions: Dokhwaljihwang-tang can be used for enhanced recovery after cancer surgery.

Analysis of the Acceleration Characteristics on the Conventional line for Korean High Speed Train- in il point of passing speed on the curve (한국형 고속전철의 기존선 주행 진동가속도 특성 분석 - 곡선 통과속도 중심으로)

  • 김영국;김석원;목진용;박찬경
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2004.05a
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    • pp.222-227
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    • 2004
  • Korean High Speed Train(KHST) has been tested on the high speed test line in Osung site, since it was developed through the G7 Project Plan in 2002. It was also tested on the conventional line such as KyongBu and Honan Line to know the possibility of increasing the limited speed for the high speed trains. This paper introduces the method to improve the speed on the conventional line with body lateral acceleration among the several considered issues and explains the parameters related to those analysis, such as the cant deficiency, the radius of curve, speed and etc. When a train pass on the curved track, the lateral accelerations of body are divided into the quasi-static and the maximum accelerations according to the UIC 518 which is the international specification for testing and approval of railway vehicles from the point of view of their dynamic behaviour, especially for safety and ride comfort. This paper shows that it is safe and comfort from the results of test when KHST runs on the conventional line with the curves and proposes that the limited speed of conventional curved line could be changed to a little higher speed if the analysises of other fields are completed.

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RECONSTRUCTION USING MANDIBULAR HORIZONTAL DISTRACTION OSTEOGENESIS AND IMPLANT PROSTHESIS IN MANDIBULAR DEFICIENCY : A CASE REPORT (하악골 결손환자에서 수평적 골 신장술과 임프란트 보철수복 : 증례보고)

  • Shin, Min-Young;An, Jun-Hyun;Han, Jung-Hwan;Shin, Sung-Soo;Park, Yang-Ho;Park, Young-Ju;Park, Jun-Woo;Rhee, Gun-Joo
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.29 no.6
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    • pp.444-449
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    • 2003
  • Distraction osteogenesis is a biologic process in which new bone is formed between bone fragments being separated by a tractional force. This technique has the advantage of initiating new bone growth without bone transplantation and promoting the growth of soft tissue. Mandibular distraction osteogenesis has shown to be effective to treat congenital or acquired mandibular hypoplasias. On the basis of positive results with implant-supported prostheses, the use of implants in the distracted site can significantly help stabilize the prosthesis. We obtained good result in the patient with mandibular deficiency due to trauma, who have been reconstructed with distraction osteogenesis and implant. We report our experiences with literature view.

A Flow Analysis of a Refrigeration Warehouse where an Unusual Death of an Operator Occurred by Deficiency of Oxygen

  • Park, Chan-Seong;Moon, Jung-Eun;Kim, Yoon-Ho;Kim, Jin-Pyo
    • International Journal of Safety
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    • v.5 no.2
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    • pp.29-33
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    • 2006
  • A numerical flow analysis of the case of a refrigeration warehouse where an unusual death of an operator occurred by deficiency of oxygen is performed by using STAR-CD program of the computational fluid dynamics (CFD) code. The refrigeration room of the warehouse for storing the fruits maintains an atmosphere of 95% nitrogen and 5% oxygen by volume. When the operator was found dead in the refrigeration room, the room was in normal operating conditions except for the fact that the auxiliary door had been left open. For the flow analysis, unsteady 3-dimensional natural convection with mass transfer is considered. The flow analysis result is compared with the oxygen concentration level measured against time during on-site investigation. The change in oxygen concentration level in the warehouse due to the opening of the auxiliary door is found to be negligible.

The Role of Genetic Diagnosis in Hemophilia A

  • Lee, Ja Young
    • Journal of Interdisciplinary Genomics
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    • v.4 no.1
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    • pp.15-18
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    • 2022
  • Hemophilia A is a rare X-linked congenital deficiency of clotting factor VIII (FVIII) that is traditionally diagnosed by measuring FVIII activity. Various mutations of the FVIII gene have been reported and they influence on the FVIII protein structure. A deficiency of or reduction in FVIII protein manifests as spontaneous or induced bleeding depending on the disease severity. Mutations of the FVIII gene provide important information on the severity of disease and inhibitor development. FVIII mutations also affect the discrepant activities found using different FVIII assays. FVIII activity is affected differently depending on the mutation site. Long-range PCR is commonly used to detect intron 22 inversion, the most common mutation in severe hemophilia. However, point mutations are also common in patients with hemophilia, and direct Sanger sequencing and copy number variant analysis are being used to screen for full mutations in the FVIII gene. Advances in molecular genetic methods, such as next-generation sequencing, may enable accurate analysis of mutations in the factor VIII gene, which may be useful in the diagnosis of mild to moderate hemophilia. Genetic analysis is also useful in diagnosing carriers and managing bleeding control. This review discusses the current knowledge about mutations in hemophilia and focuses on the clinical aspects associated with these mutations and the importance of genetic analysis.

Isolated Glycerol Kinase Deficiency (글리세롤 키나제 단독결핍증)

  • Lee, Jong Yoon;Kim, Hui Kwon;Bae, Eun Ju;Oh, Phil Soo;Park, Won Il;Lee, Hong Jin
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.12 no.1
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    • pp.54-57
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    • 2012
  • A 3-year-old boy was transferred to emergency room (ER) with lethargy and abdominal pain. Physical examination revealed drowsy mental status but neurologically intact. Basic evaluation in ER shows hypoglycemia (43 mg/dL), hyperglycerolemia, ketonemia and ketonuria. Initial urine organic acid was performed and the result showed severe hyperglyceroluria. Under suspicion of isolated GKD, GKD gene was obtained from his DNA from white blood cell in peripheral blood and sequencing was performed. Isolated glycerol kinase deficiency (GKD) is an X-linked inborn error of metabolism that is either symptomatic or asymptomatic. GKD is due to deletions of, or mutations within, the GK gene, and there is no genotype-phenotype correlation. Gene study that we performed showed normal at a well-known mutation site, but found 4-base insertion at 79 base pair away from the beginning of exon 11.

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Growth Inhibition of Cucumber by Absorbing Excess Al at Low Soil pH (강한 산성토양에서 Al의 과잉 흡수에 의한 오이 생육장해 양상)

  • Kim, Yoo-Hak;Kim, Myung Sook;Kang, Seong Soo;Lee, Hyeong Yong
    • Korean Journal of Soil Science and Fertilizer
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    • v.45 no.6
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    • pp.925-927
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    • 2012
  • On-site diagnosis applied to soil having a symptom of yellowing and whitening in cucumber leaf and stem. Soil pH determined 4.2 by methods of on-site analysis and 4.5 by soil test analysis. High aluminum in soil solution extracted with water saturation was detected. Leaf and stem tissue were abundant in Al content but not in Ca. Also, N content of leaf and stem was low compared to normal N ranges. This symptom of cucumber assumed to be from the Al and nitrous acid gas toxicity by low soil pH and Eh. Conclusionally, symptom in leaf and stem of cucumber was alleviated and cucumber normally recovered during cultivation period by applying calcium hydroxide solution to correct soil pH up to 6.5. These results showed that low soil pH resulted in aluminum toxicity and N deficiency to plant growth in on-site farming.

A Case of Basilar Arterial Thrombosis in Ovarian Hyperstimulation Syndrome (난소 과자극증후군과 동반된 뇌바닥동맥 혈전증)

  • Park, Joon-Cheol;Lim, Su-Yeon;Bae, Jin-Gon;Kim, Jong-In;Rhee, Jeong-Ho
    • Clinical and Experimental Reproductive Medicine
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    • v.35 no.1
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    • pp.83-88
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    • 2008
  • Thromboembolic disease associated with assisted reproductive techniques is considered to be extremely rare but most serious complication. The reasons for this are thought to hypercoagulable state characteristic of OHSS due to high serum levels of estrogen, hemoconcentration and reduced circulating blood volume, but is still unclear. The risk is increased those with rare hypercoagulable conditions such as antiphospholipid antibody syndrome, protein C deficiency, protein S deficiency, antithrombin III deficiency, and those with a personal or family history of thromboembolic disease. The majority of thrombosis reported were venous site but arterial thrombosis mostly intracerebral was reported 5 cases in Korea so far. We present a case of basilar a. thrombosis at 11 days after hCG injection. The patient developed the right hemiparesis, and recovered after intraarterial thrombolysis and transluminal angioplasty. Protein S activity was decreased and vWF antigen was increased. Decreased protein S activity was also found in previous reported 4 cases, so we suggest screening test for protein S in OHSS patients.

A Study on the Improvement of Supervision Works related to Changes in Construction Projects (공공공사의 설계변경과 관련한 감리업무 개선방안에 대한 연구)

  • Kwon Chan-Soon;Kim Man-Chul;Koo Kyo-Jin;Hyun Chang-Taek
    • Proceedings of the Korean Institute Of Construction Engineering and Management
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    • autumn
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    • pp.246-249
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    • 2003
  • we classified major changes into changes based on design deficiency, changes based on the different conditions between job site and contract documents, and changes based on the Owner's need. Then we compare and analyzed applicable regulations for supervision and work performance status at the site, and elicit problems of supervision performance based on mutual contradiction in regulations, bringing up a similar example. Based on the above, we brought up a way of improvement for the elicited problem, comparing and analyzing the laws/contract provisions/instructions related with the changes and the work performance at the jobsite, and verified through interviews with professionals of various fields for the improvement. Finally this study could elicit a way of improvement in the supervision work in conjunction with changes in civil works.

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Oak Tree Canker Disease Supports Arthropod Diversity in a Natural Ecosystem

  • Lee, Yong-Bok;An, Su Jung;Park, Chung Gyoo;Kim, Jinwoo;Han, Sangjo;Kwak, Youn-Sig
    • The Plant Pathology Journal
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    • v.30 no.1
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    • pp.43-50
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    • 2014
  • Microorganisms have many roles in nature. They may act as decomposers that obtain nutrients from dead materials, while some are pathogens that cause diseases in animals, insects, and plants. Some are symbionts that enhance plant growth, such as arbuscular mycorrhizae and nitrogen fixation bacteria. However, roles of plant pathogens and diseases in natural ecosystems are still poorly understood. Thus, the current study addressed this deficiency by investigating possible roles of plant diseases in natural ecosystems, particularly, their positive effects on arthropod diversity. In this study, the model system was the oak tree (Quercus spp.) and the canker disease caused by Annulohypoxylon truncatum, and its effects on arthropod diversity. The oak tree site contained 44 oak trees; 31 had canker disease symptoms while 13 were disease-free. A total of 370 individual arthropods were detected at the site during the survey period. The arthropods belonged to 25 species, 17 families, and seven orders. Interestingly, the cankered trees had significantly higher biodiversity and richness compared with the canker-free trees. This study clearly demonstrated that arthropod diversity was supported by the oak tree canker disease.