• Korea journal of population studies
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• v.9 no.1
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• pp.32-40
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• 1986

The purpose of the paper is to examine the nature of population distribution during the past 25 years; to evaluate effect of population redistribution policies which have been adopted by the government; and to suggest desirable future policy directions. The distinctive features of population distribution during the period of 196O~85 can be summarized as progress of rapid urbanization, decrease of absolute number of rural population and heavy concentration of population in the Seoul metropolitan area which have resulted in population maldistribution among regions. The problem of population concentration in the selected one or two large urban centers was first recognized by the government as early as in 1964. Since then numerous policy measures have been adopted to reduce the population concentration into the Seoul metropolitan area and thus to guide a sound population redistribution among regions. The overall assessment of various policies on population redistribution, however, revealed that the effect of the policy efforts has not been great as they originally anticipated. Various reasons can be cited for the failure of the past policies. Among them the followings were frequently mentioned; lack of integration among policy measures; weak linkage between relocation and accommodation; and non-existence of single authority for overall implementation of the polices. Based on the past experiences the followings are suggested in pursuing future policies. First, the short-term objective or target should be clearly defined. Second, policy measures have to be designed to go with rather than against market forces. Third, indirect incentives or aids are more effective than direct controls or regulations. Fourth, local participation has to be secured in every phase of policy formulation and implementation.

• The Korean Journal of Cytopathology
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• v.10 no.1
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• pp.67-71
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• 1999

We report a case of 53-year-old man with plasmacytold transitional cell carcinoma of the urinary bladder, which may be confused with plasmacytoma. The patient initially presented with gross hematuria and dysuria for two months. Cystoscopy and radiologic studios revealed multiple intraluminal protruding masses on the urinary bladder invading perivesical fat tissue. After urinary cytologic examination and cystoscopic biopsy, radical cystectomy and pelvic lymph node dissections were done. Urine cytology showed single cells and poorly cohesive cells with round eccentric nuclei, bi-or multi-nucleation, indistinct nucleoli, coarse chromatin, and abundant basophilic cytoplasm within relatively clear background. The cytologic findings of tumor cells were similar to the plasma cells seen in plasmacytoma. The tumor of the bladder was composed on discohesive, individual cancer cells with diffuse pattern that simulated lymphoma or plasmacytoma. Immunohistochemical and electron microscopic studies clearly established the epithelial nature of the neoplasm. Recognition of this plasmacytoid type of transitional cell carcinoma of the urinary bladder can avoid the misdiagnosis.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.11-11
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• 2017

The most drought resistant among the five most important cereal crops, and a key dual-use (grain and biomass) crop in regions containing some of the world's most degraded soils, sorghum has inherent climate resilience that is likely to become more important under environmental conditions that are projected by many climate change models. The importance of sorghum might be further elevated by the development of productive genotypes that increase the extent and duration of soil cover beyond those of conventional annual crops, mitigating or even reversing losses of ecological capital through multiple crops from single plantings. Rich genetic and genomic resources have been developed to link Sorghum phenotypic diversity to its molecular basis, and in particular the genus has become a model for dissecting the molecular control of perenniality. Nature has made Sorghum perennial at least twice, and crosses between wild perennials and cultivated sorghums show the feasibility of developing genotypes with varying degrees of investment in perenniality while still providing harvestable food, feed, sugar and/or cellulose. Genetic analysis of progeny from these crosses is revealing the hereditary basis of traits related to ratooning and perenniality and providing diagnostic DNA markers. One perennial Sorghum species has adapted to continents and latitudes far beyond the reach of its progenitors, surviving stresses year after year that are only periodically experienced by conventional (annual) sorghum, and may also harbor novel alleles that may mitigate production challenges in conventional annual sorghums.

• The Plant Pathology Journal
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• v.19 no.3
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• pp.152-158
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• 2003

Stromata of the white root rot fungus, Rosellinia necatrix, were produced on diseased roots although they were reported to develop rarely in nature. Forty-two (42) out of 47 samples produced synnemata while 23 developed stromata. Forty-seven (47) isolates obtained from diseased root samples were divided into 24 mycelium compatibility groups (MCGs). Sixteen (16) out of 24 MCGs produced stromata. Single ascospore isolates from 10 stroma samples produced dsRNA-containing isolates from diseased tissue beneath stromata. The frequency of synnema production on axenic culture varied among isolates with different origin. The dsRNA was not transmitted vertically to the ascospore offspring despite the infection of various dsRNA in the parental isolates. The dsRNA was absent in 35 ascospore isolates in two stroma samples that originated from the isolates, in which dsRNA was not eliminated by hyphal tip isolation. Consequently, sexual reproduction in the white root rot fungus was suggested to produce propagules as a new infection source and to have the function to eliminate infectious factors such as mycoviruses.

• Journal of The Korean Astronomical Society
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• v.49 no.4
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• pp.137-144
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• 2016

The calibration of Very Long Baseline Interferometry (VLBI) data has long been a time consuming process. The Korean VLBI Network (KVN) is a simple array consisting of three identical antennas. Because four frequencies are observed simultaneously, phase solutions can be transferred from lower frequencies to higher frequencies in order to improve phase coherence and hence sensitivity at higher frequencies. Due to the homogeneous nature of the array, the KVN is also well suited for automatic calibration. In this paper we describe the automatic calibration of single-polarisation KVN data using the KVN Pipeline and comparing the results against VLBI data that has been manually reduced. We find that the pipelined data using phase transfer produces better results than a manually reduced dataset not using the phase transfer. Additionally we compared the pipeline results with a manually reduced phase-transferred dataset and found the results to be identical.

• Journal of the Korean earth science society
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• v.23 no.1
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• pp.52-58
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• 2002

A colorless and transparent zirconium oxide ($Zr_{0.73}Y_{0.27}O_{1.87}$) crystal has been synthesized by the Bridgman-Stockbager method. The gem-quality material is produced by adding 20${\sim}$25 wt.% $Y_2O_3$ (stabilizer) and 0.04 wt.% $Nd_2O_3$ (decolorising agent) to the $ZrO_2$ powder. It shows a vitreous luster with a slight oily appearance. Under a polarizing microscope, it shows isotropic nature with no appreciable anisotropism. Mohs hardness value and specific gravity is measured to be 8${\sim}$$8{\frac{1}{2}}$ and 5.85, respectively. Under ultraviolet light it shows a faint white glow. The crystal structure of yttria-stabilized zirconia with 0.27 at.% Y has been re-investigated, using single crystal X-ray diffraction, and confirmed to be a cubic symmetry, space group $Fm{\overline{3}}m$ ($O^5_h$) with a=5.1552(5) ${{\AA}}$, V=136.99(5) ${{\AA}}^3$, Z=4. The stabilizer atoms randomly occupy the zirconium sites and there are displacements of oxygen atoms with amplitudes of ${\Delta}/a{\sim}$0.033 and 0.11 along <110> and <111> from the ideal positions of the fluorite structure, respectively.

• Korean Institute of Interior Design Journal
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• v.13 no.5
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• pp.190-197
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• 2004

A kindergarten requires an approach to meet the nature and sense of children who is main users. This study selected 33 private kindergartens which were located within a housing site development zone in Gwangju since the 1990's, had single use, and was constructed in the last five years. Also the image assessment according to types of color scheme was made. Then the factors which affected preference by type were analyzed and the basic of color scheme in a kindergarten classroom was provided. The following results were obtained. First, types of color scheme in a classroom included identity 12.1%, similarity 51.5%, and novelty 36.4% in harmony, but no contrast and achromatic color, Secondly, the assessment of preference according to each type was mostly positive. The highest preference was found in similarity harmony of warm color(e.g. YR, Y) and bright, clear, nice, and strong images were high in assessment. The lowest preference was found in identity harmony of cold color(e.g. GY). This color system had no clear image assessment, except manly or strong. In particular, warm color showed higher preference than cold color in similarity, novelty, and identity harmony. Thirdly, the factors affecting the preference of color scheme in a classroom most were ‘stable - unstable’, ‘clean - dirty’, ‘bright - dark’, ‘nice - not nice’, and ‘vital - dull’.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.15
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• pp.6211-6217
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• 2014

Previous genome-wide association studies (GWAS) have implicated several single nucleotide polymorphisms (SNPs) in the AT-rich interactive domain 5B (ARID5B) gene with childhood acute lymphoblastic leukemia (ALL). However, replicated studies reported some inconsistent results in different populations. Using meta-analysis, we here aimed to clarify the nature of the genetic risks contributed by the two polymorphisms (rs10994982, rs7089424) for developing childhood ALL. Through searches of PubMed, EMBASE, and manually searching relevant references, a total of 14 articles with 16 independent studies were included. Odds ratios (ORs) with 95% confidence intervals (95%CI) were calculated to assess the associations. Both SNPs rs10994982 and rs7089424 showed significant associations with childhood ALL risk in all genetic models after Bonferroni correction. Furthermore, subtype analyses of B-lineage ALL provided strong evidence that SNP rs10994982 is highly associated with the risk of developing B-hyperdiploid ALL. These results indicate that SNPs rs10994982 and rs7089424 are indeed significantly associated with increased risk of childhood ALL.

• Advances in concrete construction
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• v.8 no.4
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• pp.277-283
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• 2019

In evaluating explosion-protection capacity, safety distance is broadly accepted as the distance at which detonation of a given explosive causes acceptable structural damage. Safety distance can be calculated based on structural response under blast loading and damage criteria. For the applicability of the safety distance, the minimum required stand-off distance should be given when the explosive size is assumed. However, because of the nature of structures, structural details and material characteristics differ, which requires sensitivity analysis of the safety distance. This study examines the safety-distance sensitivity from structural and material property variations. For the safety-distance calculation, a blast analysis module based on the Kingery and Bulmash formula, a structural response module based on a Single Degree of Freedom model, and damage criteria based on a support rotation angle were prepared. Sensitivity analysis was conducted for the Reinforced Concrete one-way slab with different thicknesses, reinforcement ratios, reinforcement yield strengths, and concrete compressive strengths. It was shown that slab thickness has the most significant influence on both inertial force and flexure resistance, but the compressive strength of the concrete is not relevant.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3025-3033
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• 2016

Chronic myeloid leukaemia (CML) is a clonal myeloproliferative hematopoietic stem cell disorder. Deregulated BCR-ABL fusion tyrosine kinase activity is the main cause of CML disease pathogenesis, making BCR-ABL an ideal target for inhibition. Current tyrosine kinase inhibitors (TKIs) designed to inhibit BCR-ABL oncoprotein activity, have completely transformed the prognosis of CML. Interruption of TKI treatment leads to minimal residual disease reside (MRD), thought to reside in TKI-insensitive leukaemia stem cells which remain a potential reservoir for disease relapse. This highlights the need to develop new therapeutic strategies for CML either as small molecule master TKIs or phytopharmaceuticals derived from nature to achieve chronic molecular remission. This review outlines the past, present and future therapeutic approaches for CML including coverage of relevant mechanisms, whether ABL dependent or independent, and epigenetic factors responsible for developing resistance against TKIs. Appearance of mutant clones along the course of therapy either pre-existing or induced due to therapy is still a challenge for the clinician. A proposed in-vitro model of generating colony forming units from CML stem cells derived from diagnostic samples seems to be achievable in the era of high throughput technology which can take care of single cell genomic profiling.