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Modulative Effect of Human Hair Dermal Papilla Cell Apoptosis by Acertannin from the Barks and Xylems of Acer ginnala Maxim (신나무 유래 Acertannin의 인체 모유두 세포 Apoptosis 조절 효능)

  • Joung, Seo Woo;Choi, Sun Eun
    • Korean Journal of Pharmacognosy
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    • v.49 no.1
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    • pp.7-14
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    • 2018
  • We isolated gallotannin, 2,6-digalloyl-1,5-anhydroglucitol, known as acertannin (1), from the barks and xylems of Acer ginnala Maxim. It is a genus of Acer species of shrubs in the family Aceraceae. A. ginnala grows in Korea, Japan and Mongolia. We accomplished the structure elucidation by confirming that the result of $^1H$,$^{13}C-NMR$,MS spectrum data was similar to previous references. We measured DPPH and ABTS radical scavenging activity in vitro to evaluate anti-oxidative activities on acertannin isolated from A. ginnala. Acertannin from A. ginnala exhibited potent DPPH and ABTS radical scavenging activities. We examined the antioxidant and apoptosis modulative effects. This examination shows that A. ginnala has not only 1,1-diphenyl-2-picryhydrazyl(DPPH) radical scavenging activity and ABTS radical scavenging activity, but also human hair dermal papilla cell protection effects. These results indicate that the barks and xylems of A. ginnala might be developed as a potent anti-oxidant, hair growth agent, and ingredient for related new functional cosmetic materials.

The Study of the Printability on the Phenol Free Heat-Set Web Inks(II) - Analysis by the trial printing test - (Phenol Free Heat-Set 윤전 잉크의 인쇄적성에 관한 연구(제2보) - 실 인쇄 실험에 의한 분석 -)

  • Ha, Young-Baeck;Oh, Sung-Sang;Lee, Won-Jae
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.44 no.3
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    • pp.41-48
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    • 2012
  • Materials used for the inks in the printing industry is an important material following the paper. The composition of the ink is pigment and organic solvents. However, Ink is used in a variety of chemicals, they are classified as non-green. Therefore, rosin-modified phenolics manufactured by the reaction of phenol and formaldehyde can take the place of eco-phenol free resin and by experiment density, gloss, trapping, contrast and dot gain of printing has been studied as printability. The result of study can support that the properties of printing using eco-phenol free resin such as density, gloss, contrast and trapping is similar to existing ink. In the part of dot gain, the result is excellent. So we were thought to be able to improve some characteristics such as dispersion of black ink, that will be possible for the field applicability.

Optimization for Drop and Lift of the SONAR Under the Limited Installment Space Using the GA (GA를 이용한 제한된 설치환경 하에서의 소나 투하 및 인양 장비의 최적화)

  • Park, Seong-Hak;Chung, Won-Jee;Kim, Hyo-Gon;Choi, Jong-Kap
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.25 no.5
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    • pp.321-328
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    • 2016
  • Cranes are generally used to drop or lift equipment or materials. The present study focuses on equipment used for dropping and lifting the sonar system for undersea exploration. This study deals with a GA-based MATLAB$^{(R)}$ simulation for the design optimization of a new overboarding prototype with a two degree-of-freedom mechanism, including a parallelogram link, which is efficient in sonar system operation and maintenance. First, the strengths and weaknesses of the existing overboarding mechanisms are analyzed. The new mechanism to solve these problems is then suggested. For the proposed mechanism, the GA-based MATLAB$^{(R)}$ simulation technique is applied to the proposed mechanism to optimize the link lengths and the actuator lengths. By doing this, the mechanism cannot interfere in the hull's internal environment. Hence, the work range of motion (ROM) is satisfied, and good torque-angle properties are obtaind. The developed technology will be helpful in calculating the maximized output torque of the actuator for the application in practice using a similar type of the proposed mechanism.

Effect of Diuresis on Plasma Renin Activity and Aldosterone Concentration in Normal and Toxemic Pregnancy (정상임부와 임신중독환자의 혈장 Renin활성도 및 Aldosterone 농도에 미치는 이뇨의 효과)

  • Sung, H.K.;Lee, H.S.;Cho, S.S.;Koh, J.H.;Lee, J.K.;Kim, H.S.
    • The Korean Journal of Nuclear Medicine
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    • v.7 no.1
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    • pp.45-50
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    • 1973
  • The changes of plasma renin activity, aldosterone concentration, serum sodium-, and potassium levels were studied before and after the water loading followed by diuretics injection. The materials were: 13 non-, 11 normal-, and 11 toxemic pregnancy cases. The plasma renin activity and aldosterone concentration of the cord and postpartum blood were also measured. Following were the results: 1. The plasma renin activity was elevated significantly in normal pregnancy, and slightly in toxemic pregnancy. The serum sodium levels were decreased in pregnancy. 2. The plasma aldosterone concentration was slightly decreased in normal pregnancy, and slightly increased in toxemic pregnancy, however, statistically insignificant. 3. The plasma renin activity of the cord and postpartum blood were lower than those of pregnancy cases. 4. The changes of plasma renin activity after the diuretic administration showed an initial increase, which recovered within 2 hours. These changes were the least in normal pregnancy, and the most in toxemic pregnancy. 5. The changes of plasma aldosterone concentration after the diuretic administration were similar to those of plasma renin activity, although the variations were not so wide.

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Effect of Deodeok Extract on the Skin Function Improvement (증숙된 더덕 추출물의 피부기능 개선 효과)

  • Lee, Hee-Gyeong;Choi, On-Yu;Choi, Du-Bok;Choi, Hyun-Suk
    • The Korean Journal of Food And Nutrition
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    • v.33 no.5
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    • pp.505-511
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    • 2020
  • In this study, hot water and ethanol, acetone, and hexane extracts of the steamed Deodeok were investigated for use as raw materials for natural cosmetics. Hot water and ethanol, acetone and hexane extracts of steamed Deodeok did not indicate cell toxicity up to 300 ㎍/mL concentration in the MTT assay. The tyrosinase inhibition effects of the ethanol extract were higher than the ascorbic acid. The efficacy of the steamed Deodeok's ethanol extract on the elastase inhibition was similar to that of quercetin at higher concentrations. In conclusion, water, ethanol, acetone and hexane extracts of the steamed Deodeok indicated strong possibility as a whitening and anti-wrinkle functional cosmetic ingredient. Among them, the steamed Deodeok's ethanol extract, which showed excellent activity, is highly available because it has high safety compared to other organic solvent extraction methods used in cosmetics, and has minimal irritation to the skin.

A Study on the Characteristics of Clothing and Configuration of Item in Foreign Adaptive-Clothing for the Disabled Seniors (국외 거동불편노인을 위한 기능성의류에 나타난 의복의 특성 및 아이템 유형)

  • Lim, Hyun-Jung;Lee, Kyoung-Hee
    • Fashion & Textile Research Journal
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    • v.13 no.1
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    • pp.17-24
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    • 2011
  • This study aims to provide basic materials for adaptive-clothing development for disabled seniors by considering the characteristics of design with both functionality and beauty, which is displayed to overseas functional clothing for disabled seniors. After 341 photographs from 15 overseas websites which sold adaptive-clothing for disabled seniors were collected, their designs were analyzed. The content analysis and frequency analysis using the descriptive statistics were performed as the analytical methods for this study. The results are as follows; first, the design of buttons uses snap fasteners, zippers, Velcro fasteners and rubber bands so as to attach easily and keep fasteners unseen. Second, the used open system is the Back open, the Side open, the Front open and the Hip open. Third, in terms of design, the change follows easy and loose silhouette in order to act comfortably outdoors as well as indoors by making the design of onepiece dresses, jackets and cardigans similar to ordinaries. From the details aspect, a few trimmings such as color, patterns, ruffles around edge, laces and smooth shirring do not stand in the way and give mental please.

The Study of the Compatibility of MSDS for the Classification of Flammable Materials (위험물의 분류를 위한 MSDS 이용의 적정성 연구)

  • Kwon, Kyung-Ok
    • Fire Science and Engineering
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    • v.21 no.3
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    • pp.56-60
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    • 2007
  • The usage of MSDS (Material Safety Data Sheet) is increased world widely for the implementation of GHS and REACH. In order to know the accuracy of the data in MSDS the flash point of n-Decanol was measured by using a Tag closed tester, a Seta-flash closed tester, a Pensky-Martens closed tester and a Cleveland open tester in Japan and Korea, respectively. The test results of flash points of n-Decanol purchased different manufacturer were compared to the data of the references and MSDS. The flash points determined in Japan were similar to those in Korea but have shown much difference from those in MSDS and literatures. It is suggested that the results of flash points determined in this research have validity and manufacturers should be more careful when they make MSDS as well as for the classification of GHS and REACH.

Bond Strength Characteristics of Bonded Concrete Overlay (접착식 콘크리트 덧씌우기의 부착강도 특성 분석)

  • Park, Jong Won;Kim, Young Kyu;Lee, Seung Woo;Han, Seung Hwan
    • International Journal of Highway Engineering
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    • v.15 no.4
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    • pp.1-9
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    • 2013
  • PURPOSES : Bonded concrete overlay is a favorable maintenance method since the material properties are similar to existing concrete pavements. In addition, bonded concrete overlay has advantage of structural performance since the overlay layer and the existing pavement perform as a monolithic layer. It is important to have suitable bond strength criteria to secure the performance of bonded concrete overlay. This study aimed to investigate the factors influencing bond strength characteristics between existing concrete pavement and overlay material. METHODS: Bond strength between overlay and existing pavement are measured and analyzed for various conditions such as the type of overlay materials, compressive and flexure strength of overlay and existing pavement, and deterioration status of existing pavement. RESULTS: The strength of overlay material does not significantly influence the bond strength. The overlay of ultra-rapid hardening cement generally gives low bond strength. However, ultra rapid hardening polymer modified concrete gives robust bond strength. The deterioration of existing concrete significantly decrease the bond strength. CONCLUSIONS: Bond strength of bonded concrete overlay highly depends on condition of existing concrete pavement rather than overlay material.

The Larval Age and Mouth Morphology of the Black Soldier Fly, Hermetia illucens (Diptera: Stratiomyidae)

  • Kim, Won-Tae;Bae, Sung-Woo;Park, Hae-Cheol;Park, Kwan-Ho;Lee, Sang-Beom;Choi, Young-Cheol;Han, Sang-Mi;Koh, Young-Ho
    • International Journal of Industrial Entomology and Biomaterials
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    • v.21 no.2
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    • pp.185-187
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    • 2010
  • Most studies of the black soldier fly, Hermitia illucens, widely distributed throughout Southeast Asia and America focused on the use of larvae for recycling various organic materials and feed for fish and livestock. To recognize the instars of the soldier fly's larvae, we examined the number of exuviae originated from each larva from 1st instar to pupa. The weight and the head capsule width of the black soldier fly larvae also confirmed that the black soldier fly was passed through 6th instars. In addition, we found that the black soldier fly larvae had a well developed mandibular-maxillary complex, similar to those reported from the larvae of scavengers including Odontomyia cincta, Neopachygaster maculicornis, Ptecticus brunettii and Stratiomys ruficornis.

A Study on the Machinability of High Strength Steel with Internally Cooled Cutting Tool (공구내부냉각에 의한 고장력합금강의 피삭성에 관한 연구)

  • 김정두
    • Tribology and Lubricants
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    • v.5 no.1
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    • pp.44-50
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    • 1989
  • High strength steel is similar to carbon steel in its composition. This material is developed originally for special uses such as aerospace and automobile due to its high strength and shock-free property in spite of lightness. But the chemical attraction of high strength steel is serious, which includes comminution of formation, metalization and strengthening. Machining results in built-up edge between this material and the tool. Especially the work hardening behavior results in tool life shortening, which was caused by temperature generation during machining. In this study, cooling system was made in which liquid nitrogen is supplied to circulate in order to make up for these weaknesses. Machining of high strength steels, which is recognized as difficult to machine materials, was conducted after tool is cooled at -195$\circ$C. Experimental results showed that the tool was cooled down rapidly below -195$\circ$C in about 200 seconds. The tool temperature of machining with cooling system was lowered by 60~95$\circ$C than that of machining in room temperature. The hardness of the surface of chip is decreased by machining with cooling system. And the machining using the cooling system made it possible to increase shear angle, to retain smooth surface on chip without built-up-edge and to get a better roughness.