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Anti-hypertensive Activity of New Potato(Solanum tuberosum) Variety of Gui Valley Via Inhibition of Angiotensin Converting Enzyme (안지오텐신 전환효소활성 저해에 의해 항고혈압 효과를 갖는 신품종 감자 구이벨리 추출물)

  • Kim, Kwan-Hyun;Kim, Sun-Hee;Lee, Eun-Ok;Kwon, Hyun-Jung;Choi, Jong-Won;Lim, Hak-Tae;Kim, Sung-Hoon
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.1
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    • pp.93-96
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    • 2009
  • This study was attempted to investigate the anti-hypertensive activity of Solanum tuberosum, cv. Gui valley. Ethanol extract of Gui vally (EGV) increased free radical scarvenge activity up to 91.6% of control at $200{\mu}g/m{\ell}$. It's anti-oxidant activity is similar to 10 uM of ascorbic acid, well known as antioxidant. EGV inhibited Angiotensin-I-converting enzyme (ACE) activity in vitro. ACE plays a important role in regulation of blood pressure and ACE inhibitors are important for the treatment of hypertension. Anti-hypertensive activity of EGV in vivo was assessed in lead acetate (LAT)-induced hypertensive rats for 8 weeks. Elevated blood pressure in control group was significantly decreased by EGV at 200 mg/kg. Also, ACE activity in blood was also suppressed by EGV treatment. Taken together, these results suggest that EGV has an anti-hypersive activity via inhibition of ACE and can be used for the treatment or prevention of hypertension.

Evaluation of Steel Corrosion and Flexural Strength Coated with Cementitious Repair Material (시멘트계 보수재료로 코팅된 강재의 부식 및 휨강성 평가)

  • Yoon, Yong-Sik;Kim, Tae-Sang;Kim, Ho-Ryong;Kwon, Seung-Jun
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.4 no.3
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    • pp.243-249
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    • 2016
  • The present work is for an evaluation of resistance to corrosion in steel coated with cementitious repair material, so that 3 cases of steel plate(Normal, Welding, Welding & coating case) are subjected to ICM(Impressed Current Method) for acceleration of corrosion for 7days. Tested and estimated corrosion ratio through Faraday's Law are compared, and the related flexural strength are evaluated. In Normal and Welding cases, similar level of corrosion ratio(70%) is evaluated, however only 17% level of corrosion ratio is evaluated in the Welding & coating case, which indicates that cementitious repair material is effective to anti-corrosion due to a block of chloride penetration. The flexural test results are consistent with those in accelerated corrosion test, which shows a significant flexural strength in Welding & coating case by 3.4times greater than the others. The cementitious material repair coating is evaluated to be effective to anti-corrosion in welding of steel plate.

A Study on Combustion Gases Toxicity Evaluation of Polymeric Material (고분자재료의 연소가스 독성평가에 관한 연구)

  • 박영근
    • Fire Science and Engineering
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    • v.15 no.3
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    • pp.7-13
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    • 2001
  • In this paper, we had analyzed comsbustion gases according to pyrolysis $600^{\circ}c$, $800^{\circ}c$ and $1000^{\circ}c$ for polymeric material using a GASTEC colorimetric gas detector tube in order to combustion gases toxicity evaluation for flame retardant untreated ply wood, flame retardant treated ply wood, flexible polyvinyl chloride and flexible polyurethane foam of polymeric material. As a result, comsbustion gases producted from small specimens of polymeric material had reached fatal to man at a 30 minute exposure time that had possesed toxicity index. Toxicity index at pyrolysis $800^{\circ}c$ of flexible polyvinyl chloride was 31.74. Flexible polyvinyl chloride was the highest toxicity index of flame retardant untreated ply wood, flame retardant treated ply wood, flexible polyvinyl chloride and flexible polyurethane foam. The comsbustion gases producted commonly no concern with pyrolysis temperature had analyzed carbon dioxide($CO_2$) and carbon monoxide(CO). Toxicity index had investigated differently according to pyrolysis temperature even a similar materal.

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Molecular identification of oriental medicinal plant Schizonepeta tenuifolia bunge (Hyung-Gae) by multiplex PCR

  • Jigden, Baigalmaa;Wang, Hongtao;Kim, Yeon-Ju;Samdan, Narantuya;In, Jun-Gyo;Yang, Deok-Chun
    • Plant Biotechnology Reports
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    • v.4 no.3
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    • pp.223-228
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    • 2010
  • Schizonepeta tenuifolia (Korean name "Hyung- Gae") is an oriental medicinal plant that is widely used in Korea, China and Japan. S. tenuifolia (Hyung-Gae) has many pharmacological activities and is mostly used for many medicinal preparations. The dried aerial part (spikes and stems) of three oriental medicinal plants, S. tenuifolia (Hyung-Gae), Agastache rugosa (Kwhak-Hyang) and Elsholtzia ciliata (Hyang-Yoo) belonging to the same family, mint family Labiaceae, have such similar shape and smell that it is difficult to differentiate between them. The trnL-F regions of chloroplast DNA of the three medicinal plants were sequenced and used as targets in multiplex PCR reaction to identify S. tenuifolia. After alignment of trnL-F sequences of the authenticated plant samples, one single nucleotide polymorphism (SNP) specific to S. tenuifolia was found. Based on this SNP, a new primer was designed that specifically amplifies the trnL-F region of S. tenuifolia. The established multiplex-PCR was proven to be effective in the differentiation of commercial S. tenuifolia samples from A. rugosa and E. ciliata. This rapid and accurate molecular method is highly promising for use in the food industry.

A Finite element stress analysis of abutment screw according to the implant abutment material (임플란트 지대주 재질에 따른 지대주나사의 유한요소 응력 분석)

  • Kim, Nam-Sic;Lee, Myung-Kon;Hong, Min-Ho
    • Journal of Technologic Dentistry
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    • v.38 no.1
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    • pp.1-6
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    • 2016
  • Purpose: The present study was to determine the stress distribution of an abutment screw according to implant abutment material. Methods: This study was a tightening torque 10 Ncm, 20 Ncm, set to 30 Ncm, and a titanium alloy (Ti-6Al-4V), PEEK (polyetheretherketone), Endoligns (60% Carbon Fiber Reinforced PEEK) material of the custom abutment titanium alloy (Ti-6Al-4V) the stress distribution in the material of the abutment screw will be evaluated by the finite element analysis. Results: Abutment screw most stress has been concentrated on the interface between the fixture and the abutment was also part of the interface that the threads are started. Depending on the abutment of the abutment screw Material von Mises stress values are shown differently. 10Ncm T10 under the tightening torque of 294.2 MPa, P10 is 562.8 MPa, appeared to E10 is 295.8 MPa, 20Ncm tightening torque under T20 is 581.1 MPa, P20 is 1125 MPa, E20 was shown to 585.1 MPa, 30Ncm tightening torque under T30 is 918.2 MPa, P30 is 1795 MPa, E30 has appeared 925.1 MPa. Conclusion: If the abutment is used as Endoligns, it was confirmed that the abutment screw exhibits of von Mises stress value is similar to the titanium alloy abutment.

Development of Seismic Performance Evaluation Reinforcement by FRP and Ductile Material Layered Composites (섬유강화플라스틱과 연성재 적층복합체로 구성된 내진성능보강재의 개발)

  • Chang, Chun-Ho;Jang, Kwang-Seok;Kim, Ki-Hong;Joo, Chi-Hong
    • Proceedings of the KSR Conference
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    • 2010.06a
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    • pp.1486-1491
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    • 2010
  • Recently, the frequency and magnitude of the earthquake have increased. The structural safety of the public facilities such as bridges and tunnels etc. which were not concerned for earthquake resistant design are increased. Fiber reinforcement polymer that has been frequently studied for seismic retrofit has advantage as seismic reinforcement material, but it has disadvantage of the brittleness. Therefore, the investigation of safety and seismic reinforcement are required. In this study, new FRP-ductile material layered composites proposed to seismic performance reinforced of subway tunnel. Tensile test of FRP-ductile material layered composites showed that Maximum tensile force of FRP-ductile using Aluminum is similar to existing FRP reinforcement material and maximum strain was increased. In case of application of domestic subway tunnel which need ductility, layered composites of FRP-Aluminum is estimated effectively for increase of seismic performance.

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Evaluation of Domestic Tack-Coating Material's Properties for Asphalt Concrete Pavement (국내 아스팔트 콘크리트 포장용 택코팅제의 기초물성 평가)

  • Lee, Jaejun;Kim, Seung-Hoon;Lim, Jaekyu;Han, Jongmin;Lee, Kwang-Joon
    • International Journal of Highway Engineering
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    • v.16 no.6
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    • pp.121-128
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    • 2014
  • PURPOSES : The objective of this study is to evaluate the tack-coating material's properties using the bitumen bond strength(BBS) test and damping test as function of changed curing times. In this study, bonding strength tests were performed according to the curing time of tack coating materials. METHODS : In order to investigate bonding characteristic of tack coating materials, the Pneumatic Adhesion tensile Testing Instrument(PATTI) device is used to measure the bond strength between the tack coating materials and aggregate substrate based on the AASHTO TP-91. Also, damping test as in situ test was used to determine an appropriate traffic openting time for construction vehicle. Four different tack-coating materials were used in this study. The BBS tests were performed a one hour curing and testing temperatures of $5^{\circ}C$, $15^{\circ}C$, and $25^{\circ}C$. Damping test was conducted at 30min, 60min, 90min, and 120 min of curing times with temperatures of $20^{\circ}C$ and $30^{\circ}C$. RESULTS and CONCLUSIONS : The BBS test results show various bond strength as function of tack coat materials. At the same testing condition, A tack coat material shows almost two times higher than D tack coat materials although both materials are satisfied the criteria of material's physical properties. Also, Dampting test results shows similar trend with BBS test result. The damping test result was significantly changed as function of tack coat materials. Based on this study, the tack coating material's curing time is very important. Therefore, both curing time and the bond strength's characteristic has to be considered in standard specification.

Investigation on the Growth of Tungsten Carbide Layer as a Buffer for GaN-on-Si Technology (GaN-on-Si 기술을 위한 탄화텅스텐 버퍼층의 성장에 관한 연구)

  • Cho, Sungmin;Choi, Junghoon;Choi, Sungkuk;Cho, Youngji;Lee, Seokhawn;Chang, Jiho
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.30 no.1
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    • pp.1-6
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    • 2017
  • Tungsten carbide (WC) has been suggested as a new buffer layer for the GaN-on-Si technology. We have investigated and optimized the sputtering condition of WC layer on the Si-substrate. We confirmed the suppression of the Si melt-back phenomenon. In addition, surface energy of WC/Si layer was measured to confirm the possibility as a buffer layer for GaN growth. We found that the surface energy(${\gamma}=82.46mJ/cm^2$) of WC layer is very similar to that of sapphire substrate(${\gamma}=82.71mJ/cm^2$). We grow GaN layer on the WC buffer by using gas-source MBE, and confirm that it is available to grow a single crystalline GaN layer.

The Physiological Responses of Material-improved Working Clothes for Construction Site Worker (건설현장 작업복의 소재 기능성 향상에 따른 생리반응)

  • Kim, Seong-Suk;Kim, Hee-Eun
    • Fashion & Textile Research Journal
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    • v.13 no.5
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    • pp.752-758
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    • 2011
  • In this paper, experiments to develop working clothes and evaluated, including the current and material-improved working clothes in relation to physiological functionality measurement. Experiments were conducted on subjects after wearing working clothes in an climate chamber, and the thermo-physiological response, such as human body temperature, micro-climate within the clothes, blood pressure, heart rate were measured. In this manner, the physiological functionality of improved working clothes was compared with that of current working clothes and evaluated. The summary of obtained results is as follows: For physiological functionality evaluation through material-improved working clothes, P working clothes showed significantly lower rectal temperature than C working clothes. For mean skin temperature, P's skin temperature was significantly higher than C's in the second half of the experiment. P working clothes's temperature around the thighs in Micro climate was significantly lower than that of the C working clothes. Also, humidity within the clothes showed similar trends. During the exercise period, C working clothes showed higher blood pressure than P, but P showed higher heart rates than C. Also, the oxygen uptake amount was higher in C than P during the exercise period, it explains that the energy consumption amount of P working clothes was smaller than that of C working clothes. Of the subjective evaluation, for temperature sensation, workers wearing P working clothes felt cooler. For humidity, C working clothes showed more humidity. For comfort, P working clothes were better, and for sense of fatigue, workers felt less tired wearing P working clothes. From results above, we can see that physiological functionality improved in the material-improved working clothes in the working clothes for construction site workers. The improvement of working clothes through functionality improvements not only will provide personal pleasantness to constriction site workers, but will also generate efficiency and productivity improvements at construction sites. All in all, the continuous study of functionality improvements in working clothes taking into consideration the human body's physiological responses is required.

Preparation and Properties of Bio-inspired Waterborne Polyurethanes Containing Different Amount of Paraffin Wax

  • Kim, Hye-Lin;Kim, Ae-Li;Lee, Young-Hee;Kim, Sung Yeol;Park, Cha-Cheol;Rahman, Mohammad Mizanur;Kim, Han-Do
    • Textile Coloration and Finishing
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    • v.30 no.1
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    • pp.9-19
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    • 2018
  • To prepare bio-inspired antifouling coating materials having similar structure with lotus, self-crosslinkable waterborne polyurethanes emulsions containing paraffin wax (CWPU/P0, 0.25, 0.5, 1.0, 1.5, 2.0, the number indicated the wt% of wax) were prepared by an emulsifier-free/solvent free prepolymer mixing process. The as-polymerized CWPU/P emulsions containing 0 - 1.00wt% of paraffin wax were found to be stable after 4 months, however, CWPU/P emulsions containing 1.50 and 2.00wt% of paraffin wax were unstable within 1 month storage. Considering the stability of emulsions, the optimum paraffin wax content was found to be about 1wt% to obtain stable antifouling coating emulsion material. The surface topology of CWPU/P film samples was characterized by atomic force microscopy (AFM). This study examined the effect of paraffin wax content on the surface roughness, water contact angle/surface energy, water swelling, light transmittance and tensile properties of CWPU/P film samples.