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Development of Parameters on Depth of Anesthesia using Power Spectrum Density Analysis during General Anesthesia (전신 마취 중 전력스펙트럼 분석을 이용한 마취심도 파라미터 개발)

  • Baik, Seong-Wan;Ye, Soo-Young;Park, Jun-Mo;Jeon, Gye-Rok
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.22 no.6
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    • pp.537-545
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    • 2009
  • In this paper, new parameters were developed to estimate the depth of anesthesia during a general anesthesia using EEG. Power spectral density(PSD) analysis was used for these parameters because EEG became slow wave during anesthesia. The new parameters were DTR, ATR, TDR, ADR, BTR and BDR applied to PSD. These parameters were compared with SEF which is conventionally used at clinic and confirmed clinical value. As the results, DTR, ATR, TDR, ADR among parameters were not useful compared with SEF but BTR and BDR is valuable for clinic. 15 patents, at pre-operation BDR the value is $265.36{\pm}25.29$, at induction the value is $129.23{\pm}34.92$, at operation the value is $154.99{\pm}38.34$, at awaked the value is $283.83{\pm}39.80$ and at post-operation the value is $234.80{\pm}23.46$. Also at pre-operation BTR value is $183.38{\pm}13.59$, at induction the value is $104.09{\pm}25.11$, at operation the value is $115.38{\pm}23.42$, at awaked the value is $190.33{\pm}23.31$ and at post-operation the value is $172.38{\pm}19.08$. Trend of BDR and BTR is similar to change of SEF, so two parameters are useful. to estimate the depth of anesthesia.

Investigation on Liquid Crystal Alignment Effects of SiNx Thin Film Irradiated by Ion Beam (이온 빔 조사된 SiNx 박막의 액정 배향 효과에 관한 연구)

  • Lee, Sang-Keuk;Kim, Young-Hwan;Kim, Byoung-Yong;Han, Jin-Woo;Kang, Dong-Hun;Kim, Jong-Hwan;Seo, Dae-Shik
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2007.06a
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    • pp.398-398
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    • 2007
  • Most recently, the Liquid Crystal (LC) aligning capabilities achieved by ion beam exposure on the diamond-like carbon (DLC) thin film layer have been successfully studied. The DLC thin films have a high mechanical hardness, a high electrical resistance, optical transparency and chemical inertness. Nitrogen doped Diamond Like Carbon (NDLC) thin films exhibit properties similar to those of the DLC films and better thermal stability than the DLC films because C:N bonding in the NDLC film is stronger against thermal stress than C:H bonding in the DLC thin films. Moreover, our research group has already studied ion beam alignment method using the NDLC thin films. The nematic liquid crystal (NLC) alignment effects treated on the SiNx thin film layers using ion beam irradiation for three kinds of N rations was successfully studied for the first time. The SiNx thin film was deposited by plasma-enhanced chemical vapor deposition (PECVD) and used three kinds of N rations. In order to characterize the films, the atomic force microscopy (AFM) image was observed. The good LC aligning capabilities treated on the SiNx thin film with ion beam exposure for all N rations can be achieved. The low pretilt angles for a NLC treated on the SiNx thin film with ion beam irradiation were measure.

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A Study of Filtralite Media Applicability for Development F/A Process of Membrane Filtration Pre-treatment Process in the Water Purification Plant (정수장에서 막여과 전처리용 F/A 공정 개발을 위한 Filtralite 여재의 적용성 연구)

  • Kim, JUN-Hyun;Jun, Yong-sung;Kwak, Young-ju;Jang, Jung Woo
    • Membrane Journal
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    • v.25 no.6
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    • pp.503-514
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    • 2015
  • In this study, water purification system without coagulant was consisted of F/A and membrane to produce purified water which only uses physical treatment without coagulant. Because the use of coagulant has a possibility remaining of hazardous aluminum with our health. Especially, the Filtralite was reviewed the possibility to remove turbidity and organic material. It was found that the turbidity removal rate of Filtralite was 83~84%. It show that Filtralite has similar efficiency to sand-filter. But Filtralite has higher 50% removal rate of organic material than sand-filter due to well-developed pore on the surface of it. So, Filtralite could be used to substitute the sand-filter for the F/A process due to higher removal rate. And also coupled with activated carbon in F/A process, TMP was increased by TOC value. To prevent increasing TMP, media that has outstanding organic adsorption ability should be used.

Development of a Water-soluble Dry Lubricant for Nuclear Fuel Rod Protection (핵 연료봉 표면보호를 위한 수용성 건식 윤활제 개발)

  • Chung, Keunwoo;Kim, Young-Wun;Lee, Sangbong;Hong, Jongsung;Han, Sangjae;Oh, Myoungho
    • Tribology and Lubricants
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    • v.30 no.6
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    • pp.343-349
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    • 2014
  • Currently, in order to resist the scratching of the fuel rod surface while fabricating the fuel assembly of the light-water nuclear reactor, we use a solution of nitrocellulose, an explosive material, as a dry lubricant along with its solvent. However, the demand for developing safe and harmless aqueous alternative materials for environment-conservation and field-worker safety has increased. In this study, we demonstrate the preparation of a novel aqueous resin composite using a formulation of aqueous polymeric resin, alcoholic solvent, and water. Subsequently, we characterize this composite on the basis of hardness, adhesive property, and water solubility using plates similar to the fuel rod material. The insertion test of a fuel rod coated with the YS-3 composite shows load values of $18.8-20.5kg/cm^2$, which is comparable with $18.8-20.5kg/cm^2$ of the nitrocellulose coating agent. In addition, the depth and width of longitudinal scratches caused by the YS-3 composite test are 50% higher than those of the standard. We can develop a harmless and safe aqueous dry lubricant to replace the existing NC products through field testing of 264 pieces of fuel rods, after producing 350 kg of the YS-3 prototype. The scratch test for the rod surface showed that weight of chip of YS-3 prototype was smaller than that of NC before and after solvent treatment, indicating the properties of YS-3 prototype was comparable to the counterpart.

Hydrothermal Synthesis of $TiO_2$ Nanowire Array for Osteoblast Adhesion

  • Yun, Young-Sik;Kang, Eun-Hye;Hong, Min-Eui;Yun, In-Sik;Kim, Yong-Oock;Yeo, Jong-Souk
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.08a
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    • pp.275-275
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    • 2013
  • Osteoblast is one of cells related with osseointegration and many research have conducted the adhesion of osteoblast onto the surface of implant. In the osseointegration, biocompatibility of the implant and cell adhesion to the surface are important factors. The researches related to cell adhesion have a direction from micro-scaled surface roughness to nano-scaled surface roughness with advancing nanotechnology. A cell reacts and sense to stimuli from extracellular matrix (ECM) and topography of the ECM [1]. Thus, for better osseointegration, we should provide an environment similar to ECM. In this study, we synthesize TiO2 nanowires using hydrothermal reaction because TiO2 provides inertness to titanium on its surface and enables it used as an implant material for the orthopedic treatment such as fixation of the bone fracture [2]. Ti substrate is immersed into NaOH aqueous solution. The solution are heated at $140{\sim}200^{\circ}C$ for various time (10~720 minutes). After heat treatment, we take out the sample and immerse it into HCl aqueous solution for 1 hour. The acid treated sample is heated again at $500^{\circ}C$ for 3 hours [3]. Then, we culture osteoblast on the TiO2 nanowires. For investigating cell adhesion onto nanostructured surface, we conduct several tests such as MTT assay, ALP (Alkaline phosphatase) activity assay, measuring calcium expression, and so on. These preliminary results of the cell culture on the nanowires are foundation for investigating cell-material interaction especially with nanostructure interaction.

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Screening of Dietary Fiber Degradation Enzyme for Making Sweet Potato Soju by Vacuum Distillation (감압증류법의 고구마소주 제조를 위한 식이섬유 분해효소의 선별)

  • Takamine, Kazunori;Jeon, Byung-Hun;Kim, Won-Sin
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.26 no.1
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    • pp.35-39
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    • 2012
  • Sweet potato soju(SPS) has been made by vacuum distillation because sweet potato contains much fibrous materials which give high density to sweet potato mash. Generally, the SPS made by vacuum distillation has soft flavors and tastes. If the viscosity of sweet potato mash could be decreased by degradation enzyme, the process and production of SPS making by the method of vacuum distillation may be simplified and easier to distil the fermented sweet potato. Because the fibrous materials of sweet potato contains pectin with methoxyl group, methanol can be produced by fibrous degradation enzyme. For appling the fiber degradation enzymes to sweet potato mash for making SPS, the enzyme should be needed to degrade fibrous material without producing methanol. Special two fibrolytic enzymes are selected from 26 kind of commercial enzymes for the simplified and easier production of sweet potato soju by vacuum distillation, The selected enzyme A and X can degrade the fibrous material pectin of sweet potato without producing methanol. Although the different companies have produced the enzymes, same cellulase has been prepared from Trichoderma. reesei. The viscosity of sweet potato mash treated by the enzymes is decreased by 3 times with comparison to the viscosity of sweet potato mash of control group. The methanol concentration in the vacuum distilled SPS treated with the enzymes is 0.16%. The concentration is similar to that of commercially distilled SPS(0.15%). The result may suggest that the selected cellulases, A and X, can be used to make SPS by vacuum distillation.

Comparison of Fermentation Characteristics of Korean Traditional Alcoholic Beverages Prepared by Different Brewing Methods and Their Quality Changes after Aging (전통주의 제조방법별 발효 특성 및 숙성후 품질변화 비교)

  • Kim, In-Ho;Park, Wan-Soo;Koo, Young-Jo
    • Journal of the Korean Society of Food Culture
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    • v.11 no.4
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    • pp.497-506
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    • 1996
  • Fermentation characteristics and quality changes of the typical Korean traditional alcoholic beverages (Kwahaju, Sokokju, Baikhaju, Samhaeju and Hosanchun) were investigated during fermentation and after aging, respectively. They were prepared by their own brewing methods with respect to the same contents of rice and Nuruk (Korean-style bran koji). The consumed total sugar content of the alcoholic beverages (Sokokju, Baikhaju, Samhaeju and Hosanchun) which were brewed with the multiple input steps of seed mash and raw material (ABMIS) was higher than that of the alcoholic beverage (Kwahaju) which was brewed with the single input step (ABSIS). The pH values of all the beverages were similar and were ranged from 3.2 to 3.6. The acidity of ABMIS were lower than that of ABSIS, but alcohol concentration of ABMIS were higher. The fermentation period of the alcoholic beverages with triple input steps was the longest among them. The inner temperature and microbial growth in all the beverages increased at each of input steps of the raw materials. Fusel oil content of ABMIS was lower than that of ABSIS. Major components of the fusel oil were iso-amyl alcohol, iso-butanol, n-propanol, ethyl acetate and acetaldehyde, and its minor components were methanol and n-butanol. The results on quality changes of the alcoholic beverages after aging showed increase of alcohol in ABMIS, but decrease of sugar and acidity. Fusel oil contents of Kwahaju and Samhaeju decreased to be ranged from 3.1% to 13.9% after aging, but those of Sokokju, Baikhaju and Hosanchun increased to be ranged from 10.9% to 23.0%. Sensory evaluation of ABMIS showed better scores than that of ABSIS. It was suggested that the brewing method with multiple input steps of seed mash and raw material was one of the methods to increase fermentation efficiency for brewing the Korean traditional alcoholic beverages.

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THE ADAPTATION OF LIGHT CURED GLASS IONOMER CEMENTS TO TOOTH STRUCTURE (광중합형 글래스 아이오노머 시멘트의 치질접착에 관한 연구)

  • Hur, Seung-Myun;Cho, Young-Gon;Moon, Joo-Hoon
    • Restorative Dentistry and Endodontics
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    • v.21 no.2
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    • pp.489-504
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    • 1996
  • The purpose of this study was to compare the adaptation to the tooth structure of five light cured glass ionomer cements (Fuji II LC. VariGlass VLC, Vitremer, Dyract and Geristore). Human, non-carious fifty extracted permanent premolars stored in normal saline were used. Class V cavity preparations were created on the buccal surfaces. The occlusal margin of each cavity was placed on the enamel and the gingival margin was placed on the cementum/dentin. The teeth were then distributed at random into five groups of 10 teeth each. Group 1: Fuji II LC, Group 2 : VariGlass VLC, Group 3 : Vitremer, Group 4: Dyract, Group 5 : Geristore. The prepared cavities were restored with one of the five light cured glass ionomer cements. The manipulation of each material was handled according to the manufacturer's instructions. All samples were placed in incubator of 100% relative humidity at $37^{\circ}C$ for 24 hours. The roots of the teeth were removed with the tapered fissure bur and the remaining crowns were sectioned buccolingually through the center of restorations. The cut interfaces were gradually hand polished on sandpapers from 300 up to 1200 grit. The adaptation at the tooth/cements interface was assessed by SEM (JSM-840A, JEOL Ltd.). The results of this study were as follows : 1. Group 2 revealed the best adaptation and groups 1, 4 and 5 revealed similar adaptation pattern to the cavity walls. Group 3 revealed the worst adaptation to the cavity walls. 2. Enamel margins showed better adaptation than dentin/cementum margins with each material except group 3. 3. The hybrid layers were observed between the glass ionomer cement and dentin in groups 2, 4 and 5.

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Antiaging and antioxidant activity of Hypsizygus marmoreus extracts (흰만가닥버섯(Hypsizygus marmoreus)추출물의 항노화 및 항산화 활성)

  • Kwon, Hye-Jin
    • Journal of the Korean Applied Science and Technology
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    • v.35 no.4
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    • pp.1081-1087
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    • 2018
  • This study was carried out to investigate the effects of the extracts of 80% EtOH and EtOAc, BuOH, and D.W in Korean native Hypsizygus marmoreus. Antioxidation and antioxidant analysis to provide the possibility of a multifunctional cosmetic raw material. As a result of analyzing the cytotoxicity of the sample using the animal cell line HaCaT cell, it was confirmed that the toxicity of the sample hardly affected the cells. The inhibition rate of elastase was 30.41% at 10% of sample concentration and inhibition activity of collagenase was 11.65% at 1% of sample concentration. Hypsizygus marmoreus showed better antioxidant activity than similar mushroom. The total phenol contents of the fractions were 778.4 mg and 2.59 mg per 1 g of white mushroom, confirming its potential as a natural antioxidant. As a result, the extract of Hypsizygus marmoreus is considered to be highly valuable as a natural cosmetic material having antioxidant and antioxidant functions.

A Study on the Property Change of the Transparent Film for Vehicle Cover according to Weathering Test (차량 덮개용 투명 필름 내후 시험에 따른 물성변화 연구)

  • Kim, Ji-Hoon;Kim, Byung-Soon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.8
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    • pp.174-180
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    • 2019
  • In this study, we evaluated and analyzed the properties of polymeric transparent films used in military vehicle covers according to weathering test. Two types of polymer films (Film A and Film B) that are mostly used for military vehicle covers were selected. The weathering treatment condition and tester are described in KS K 0706, and the following weathering times were tested: 0hour, 40hours, 160hours and 320 hours. The tensile strength, elongation and thermal decomposition behavior and optical characteristics were analyzed. The tensile strength tended to decrease - increase - decrease with increasing weathering treatment time in both transparent films. The thermal decomposition temperature gradually decreased. Regarding the optical property, the light transmittance decreased and the haze tended to increase. However, film A showed almost similar optical characteristics after 160-hour weathering treatment.