• Journal of Dental Rehabilitation and Applied Science
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• v.24 no.1
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• pp.29-40
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• 2008

The purpose of this study was to evaluate the prevalence of symptoms and signs of temporomandibular joint dysfunction (TMD) and malocclusion in 10-12 year old children and to determine if a relationship exists between symptoms and signs of TMD and malocclusion. The subjects were composed of 465 school children (233 boys and 232 girls). Each subject was evaluated with simplified questionnaire and clinical examination to measure symptoms and signs of TMD and malocclusion. The results showed an elevated prevalence of headache (34.6%), which were more frequent in girls than boys. The most common cardinal sign of TMD was clicking (32.9%), which increased with age. TMJ lateral tenderness was present in 18.1% of the subjects and had a tendency to increase with age. Masseter muscle tenderness was found to be sensitive in 15.1%of the subjects and had a tendency to increase with age. Restriction of mandibular mobilitywas present in 30.3% of the subjects and had a tendency to increase with age. There was no significant difference in the prevalence of TMD signs between sex. The occlusal status showed Class I malocclusion in 73.3%, Class III in 12.9%,Class II division 1 in 11%, Class II division 2 in 2.8%. There was no significant difference in malocclusion traits between sex. There was statistically significant relationship between TMD signs and symptoms and class II division 1 and Class III malocclusion(p<0.05). The results indicate that the prevalence of TMD symptoms and signs in children is high, and the evaluation of TMD in children seems to be important.

• Journal of muscle and joint health
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• v.18 no.2
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• pp.158-168
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• 2011

Purpose: The purpose of this study was to compare musculoskeletal pain, menopausal symptoms and depression by women's menopausal stage. Method: With a survey design, a convenience sample of 203 women between age of 40 to 64 was recruited through a community. Data were collected via a structured study questionnaire from May to July, 2008. Measures included with symptom severity list for menopausal symptoms, Aches and Pains scale, and Beck's Depression Inventory. Results: Thirty-seven percent of women belong to early peri-menopausal stage, 31% to late peri-menopausal stage, and 32% to postmenopausal stage. By group comparison, late peri-menopausal and post menopausal women reported higher scores of depression than early peri-menopausal women. Postmenopausal women had greater scores in two pain subscales (bodily pain and pain that interferes with normal work) and two menopausal symptoms subscales (sleep pattern and sexual behaviors) than early peri-menopausal women. There were moderate levels of positive relationships among study variables at each menopausal stage. Conclusion: Postmenopausal women seem to have greater musculoskeletal pain and menopausal symptoms, and have depression more than did early peri-menopausal women. Tailored nursing strategies are required to reduce these kinds of common symptoms for women with menopausal transition to improve their physical and psychological wellbeing.

• Journal of Trauma and Injury
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• v.20 no.2
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• pp.83-89
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• 2007

Purpose: This research was performed to determine which clinical signs and symptoms of brain injury are sensitive indicators of skull fracture (SF) and intracranial injury (ICI) in head injured children. Methods: We conducted a prospective study of minor head trauma in children younger than 2 years of age for a 1-year period. Skull radiographs, brain computed tomography (CT), and data forms, including mechanism of injury, symptoms, physical findings, and hospital course, were completed for each child. Results: Of 137 study subjects, 17 (12.4%) had SF/ICI. Falls were the most common mechanism of injury, and heights of fall above 1 meter were associated with incidence of SF/ICI (p<0.05). Scalp abnormalities were not associated with incidence of SF/ICI. As for clinical symptoms, lethargy and a grouping of features (irritability & vomiting) were associated with incidence of SF/ICI (p<0.05). The incidence of seizure, loss of consciousness, vomiting, irritability, and scalp abnormality did not differ significantly between those with normal radiologic findings and those with SF/ICI. Among asymptomatic patients, 11 (14.5%) patients had SF/ICI, and among patients with normal scalp findings, 9 (12.7%) patients had SF/ICI. Conclusion: Clinical signs and symptoms, except for lethargy and a grouping of features (irritability & vomiting), were not sensitive predictors of SF/ICI. Nevertheless, SF/ICI occurred among normal children. In such a case, a liberal policy of CT scanning is warranted.

• Proceedings of the ESK Conference
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• 1993.04a
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• pp.100-109
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• 1993

To investigate the work-relatedness of carpal tunnel syndrome of some workers at packing department in a rayon manufacturing company, reseracher studied the symptoms and physical sign related to carpal tunnel syndrome of the workers at packing, ysrning, and washing department. The results are as follows: 1. By the results of ergonomic study, the packing work had the considerable probability to develop the carpal tunnel syndrome. 2. The prevalences of symptoms, physical sign and case by definition were higher in woman workers than in man workers. 3. In female workers, the age-agjusted prevalence rates of symptoms were 11.6/1, 000 in workers at washing department, 111.6/1, 000 in workers at packing department, and 70.1/1, 000 in workers at yarning department. In male workers, the age- adjusted rates of symptoms were 92.1/1, 000 in workers at washing department, 210.1/1, 000 in workers at packing and delivery department, and 0.0/1, 000 in workers at yarning department. 4. In female workers, the age-adjusted prevalence rates of physical signs were 119.5/1, 000 in workers at washing department, 104.4/1, 000 in workers at packing department, and 84.5 in workers at yarning department. In male workers, the age-adjusted rates of physical signs were 65.7/1, 000 in workers at washing department, 59.0/1, 000 in workers at packing and delivery department, and 176.9/1, 000 in workers at yarning department. 5. In female workers, the age- adjusted prevelence rates of carpal tunnel cases by case definition were 123.1/1, 000 in workers at washing department, 1117.2/1, 000 in workers at packing department, and 60.2/1, 000 in workers at yarning department. In male workers, the age-adjusted of cases were 355.9/1, 000 in workers at packing and delivery department, and 0.0/1, 000 in workers at other two departments. 6. The most of female workdrs at washing departmentn had the work history at packing department. 7. We concluded the carpal tunnel syndrome of female workers at packing department were work related.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.21 no.4
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• pp.264-270
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• 2018

Purpose: The aim of this study was to describe functional gastrointestinal disorders (FGID) presented in a tertiary medical center, characteristics of patients and results of the diagnostic work-up together with an outcome during the follow up. Methods: This was a retrospective, single center, observational study including all patients who were diagnosed with FGID based on Rome III criteria from January to December 2015 in tertiary medical center. Results: Overall 294 children were included (mean age, 8.9 years [range, 1-18 years]; 165 females). Majority had functional constipation (35.4%), followed by functional abdominal pain (30.6%), irritable bowel syndrome (17.0%), functional dyspepsia (12.6%), functional nausea (3.4%) and abdominal migraine (1.0%). Regression model found that only significant factor associated with improvement of symptoms is the establishment of the functional diagnosis at the first visit (hazard ratio, 2.163; 95% confidence inverval, 1.029-4.544). There was no association between improvement of symptoms and presence of alarm signs/symptoms (weight loss, nocturnal symptoms and severe vomiting) at diagnosis. Furthermore, in pain symptoms (functional abdominal pain, irritable bowel syndrome, dyspepsia) no treatment positively correlated with pain improvement. Conclusion: Regardless of the initial diagnosis of FGID, positive diagnosis at the first visit increases a chance for resolution of symptoms.

• Korean Journal of Veterinary Service
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• v.46 no.2
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• pp.167-173
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• 2023

An 8-year-old female neutered Maltese dog exhibited signs of serious thunderstorm phobia including panting, wandering, shivering, hiding, crying or whining, or trying to escape from the house. In this study, we administered clomipramine and alprazolam and observed behavioral improvement for 3 years. Clinical symptoms measured according to the storm phobia assessment (SPA) were significantly high with an initial total score of 19 points. However, it improved to a total score of 8 on day 176 after drugs administration and returned to the normal level with the total score of 5 points on the 983 days. When the symptoms for the first 4 treatments and the last 4 treatments were compared in 2 groups, the total score of all clinical symptoms decreased to -62.83% in the last 4 treatments. This study found that treatment with alprazolam and clomipramine was associated with a decrease in clinical signs of storm anxiety, suggesting that two drugs would be effective in reducing symptoms caused by anxiety, thunderstorm phobia, and noise phobia. In this follow up study, we hope that more studies would be conducted on behavior modification for treatment of storm phobia in veterinary medicine.

• Safety and Health at Work
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• v.4 no.3
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• pp.123-135
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• 2013

Exposure to manganese (Mn) is associated with neurobehavioral effects. There is disagreement on whether commonly occurring exposures in welding, ferroalloy, and other industrial processes produce neurologically significant neurobehavioral changes representing parkinsonism. A reviewof methodological issues in the human epidemiological literature onMnidentified: (1) studies focused on idiopathic Parkinson disease without considering manganism, a parkinsonian syndrome; (2) studies with healthy worker effect bias; (3) studies with problematic statistical modeling; and (4) studies arising from case series derived from litigation. Investigations with adequate study design and exposure assessment revealed consistent neurobehavioral effects and attributable subclinical and clinical signs and symptoms of impairment. Twenty-eight studies show an exposure-response relationship between Mn and neurobehavioral effects, including 11 with continuous exposure metrics and six with three or four levels of contrasted exposure. The effects of sustained low-concentration exposures to Mn are consistent with the manifestations of early manganism, i.e., consistent with parkinsonism. This is compelling evidence thatMnis a neurotoxic chemical and there is good evidence that Mn exposures far below the current US standard of $5.0mg/m^3$ are causing impairment.

• Journal of Korean Medical classics
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• v.22 no.1
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• pp.71-85
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• 2009

For having good therapeutic value, putting the ideal of diagnosis and treatment based on overall analysis of symptoms and signs[辨證施治] into practice is very important, so the Eastern Medicine's peculiar diagnosis without interference by the western medical diagnosis is very important. The peculiar method of Eastern Medicine's diagnosis is four methods of diagnosis(四診法), a joint term for inspection, auscultation and olfaction, interrogation, pulse feeling and palpation. In the process of interrogation[問診], from analyzing the perspiration phase, doctor can get various physical information. Especially perspiration from particular region can be a clue for founding focus or cause of disease. This thesis divide the phase of perspiration into eight bodily region, perspiration from all body, head, face, back, chest and armpit, stomach, pubic region and lower part, hands and feet, and inquire the possible causes and principles of these perspirations. In conclusion, the regional perspiration can be a clue point out the origin of fever and condition of Gi(氣) flow. Perspiration from head, back, chest and armpit, hands and feet means that certain fever cannot extend to the outside of body, and at the same time, means the Gi(氣) flow of outside is being intercepted. So the perspirations from that region become an object of medical treatment.

• Journal of Oral Medicine and Pain
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• v.18 no.2
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• pp.131-147
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• 1993

To evaluate the contribution of head/neck posture to signs/symptoms of craniomandibular disorder(CMD), the author clinically, cephalo-metrically, analyzed craniomandibular index (CMI), clinical dysfunction index(CDI), occlusal index(OI) and head posture, cervical spine, cervicovertebral anatomy, craniofacial variables from 30 CMD patients and control. And the author analyzed difference between patients and control, and the correlation between CMI, CDI and head posture, cervical spine, cervicovertebral anatomy, craniofacial variables in CMD patients and control. The obtained results were as follows : 1. There was very high significant correlation between CMI and CDI(r=0.8969, p<0.01). 2. There was significant difference between patients and control in head/neck posture, head/neck anatomy(p<0.05). 3. There was significant correlation between CMI, CDI and head posture, cervical spine, cervicovertebral anatomy, craniofacial variables(p<0.05). 4. There was more significant correlation between DI and head/neck posture, head/neck anatomy than between PI and head/neck posture, head/neck anatomy in CMD patients(p<0.05)

• Journal of Acupuncture Research
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• v.39 no.3
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• pp.229-233
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• 2022

Glossopharyngeal neuralgia is a skin-sensitive condition/disease that causes severe pain in the facial area predominantly innervated by the glossopharyngeal nerve. A 51-year-old man diagnosed with glossopharyngeal neuralgia who was hospitalized with severe pain that limited his daily life activities. From November 18, 2021, to March 4, 2022, he received inpatient (10 days) and outpatient treatment (35 times) using acupuncture, pharmacopuncture, and herbal medicine. His symptoms were assessed using the Numerical Rating Scale, Neuropathic Pain Scale, and the Self-report Leeds Assessment of Neuropathic Symptom and Signs. The pain reduced after 4 days of initiating Korean medicine treatment and was completely resolved within 4 months of treatment (Numerical Rating Scale score 4 to 0; Neuropathic Pain Scale score 49 to 8; Self-report Leeds Assessment of Neuropathic Symptoms and Signs score 18 to 0). Korean medicine treatment could be an option for treating patients with neuropathy who rely on analgesics.