• Title/Summary/Keyword: signal pathway

검색결과 830건 처리시간 0.026초

상상 움직임에 대한 실시간 뇌전도 뇌 컴퓨터 상호작용, 큐 없는 상상 움직임에서의 뇌 신호 분류 (Real-time BCI for imagery movement and Classification for uncued EEG signal)

  • 강성욱;전성찬
    • 한국HCI학회:학술대회논문집
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    • 한국HCI학회 2009년도 학술대회
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    • pp.642-645
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    • 2009
  • Brain Computer Interface (BCI) is a communication pathway between devices (computers) and human brain. It treats brain signals in real-time basis and discriminates some information of what human brain is doing. In this work, we develop a EEG BCI system using a feature extraction such as common spatial pattern (CSP) and a classifier using Fisher linear discriminant analysis (FLDA). Two-class EEG motor imagery movement datasets with both cued and uncued are tested to verify its feasibility.

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Correlation between signal pathway of chitosan and nitric oxide

  • Yoon, Hyun-Joong;Kim, Young-Ho;Park, Haeng-Soon
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.222.2-223
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    • 2003
  • Renal dipeptidase (RDPase, EC 3.4.13.19), an ectoenzyme of renal proximal tubules, is covalently bound to outer leaflet of lipid bilayer via glycosylphosphatidylinositol (GPI)-anchor. Chitin is a major component of the shells of crustacea such as crab, shrimp and crawfish. This study was conducted to examine the effect of chitosan on RDPase release from renal proximal tubules. Nitric oxide (NO), highly reactive free radical, inhibits the release of RDPase from porcine proximal tubules. (omitted)

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Biochemistry and structure of phosphoinositide phosphatases

  • Kim, Young Jun;Jahan, Nusrat;Bahk, Young Yil
    • BMB Reports
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    • 제46권1호
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    • pp.1-8
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    • 2013
  • Phosphoinositides are the phosphorylated derivatives of phosphatidylinositol, and play a very significant role in a diverse range of signaling processes in eukaryotic cells. A number of phosphoinositide-metabolizing enzymes, including phosphoinositide-kinases and phosphatases are involved in the synthesis and degradation of these phospholipids. Recently, the function of various phosphatases in the phosphatidylinositol signaling pathway has been of great interest. In the present review we summarize the structural insights and biochemistry of various phosphatases in regulating phosphoinositide metabolism.

Synaptic Facilitation of Naive and Depressed Synapses in Aplysia

  • Chang, Deok-Jin;Kaang, Bong-Kiun
    • 한국생물물리학회:학술대회논문집
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    • 한국생물물리학회 2001년도 학술 발표회 진행표 및 논문초록
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    • pp.23-23
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    • 2001
  • To evaluate the contribution of cAMP/PKA signal pathway in short-term facilitation, we overexpressed Ap oal receptor in sensory neurons that do not normally express this receptor. We have previously shown that activation of this receptor in sensory cells, by a brief treatment with octopamine (OA), produced short-term facilitation such as membrane depolarization, increase in membrane excitability, spike broadening, and enhanced neurotransmitter release in non-depressed synapse.(omitted)

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STOCHASTIC DIFFERENTIAL EQUATION MODELS FOR EXTRACELLULAR SIGNAL-REGULATED KINASE PATHWAYS

  • Choo, S.M.;Kim, Y.H.
    • Journal of applied mathematics & informatics
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    • 제31권3_4호
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    • pp.457-467
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    • 2013
  • There exist many deterministic models for signaling pathways in systems biology. However the models do not consider the stochastic properties of the pathways, which means the models fit well with experimental data in certain situations but poorly in others. Incorporating stochasticity into deterministic models is one way to handle this problem. In this paper the way is used to produce stochastic models based on the deterministic differential equations for the published extracellular signal-regulated kinase (ERK) pathway. We consider strong convergence and stability of the numerical approximations for the stochastic models.

Expression and Role of ICAM-1 in the Occurrence and Development of Hepatocellular Carcinoma

  • Zhu, Xi-Wen;Gong, Jian-Ping
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권3호
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    • pp.1579-1583
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    • 2013
  • Intercellular adhesion molecule-1 (ICAM-1) is a member of the immunoglobulin superfamily, its main function being to participate in recognition and adhesion between cells. ICAM-1 is considered closely related to occurrence, development, metastasis and invasion process of hepatocellular carcinoma (HCC). A variety of inflammatory cytokines and stimulus affect its expression through the nuclear factor-kappa B (NF-${\kappa}B$) signal transduction pathway. In the initial stage of inflammation, hepatocirrhosis and tumor development, ICAM-1 is expressed differently, and has varied effects on different cells to promote occurrence of malignancy and metastasis. ICAM-1 has diagnostic significance for AFP-negative or suspected HCC, and may be a prognositic significance. It is thus widely used in studies as a biomarker which reflects cancer cells metastasis as well as curative effect of drugs. Many new treatments of HCC may be based on the effects of ICAM-1 on different levels of function.