• Journal of Korean Neurosurgical Society
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• v.61 no.4
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• pp.434-440
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• 2018

Objective : The purpose of this study was to find an optimal delivery route for clinical trials of intrathecal cell therapy for spinal cord injury in preclinical stage. Methods : We compared in vivo distribution of Cy5.5 fluorescent dye in the spinal cord region at various time points utilizing in vivo optical imaging techniques, which was injected into the lateral ventricle (LV) or cisterna magna (CM) of rats. Results : Although CM locates nearer to the spinal cord than the LV, significantly higher signal of Cy5.5 was detected in the thoracic and lumbar spinal cord region at all time points tested when Cy5.5 was injected into the LV. In the LV injection Cy5.5 signal in the thoracic and lumbar spinal cord was observed within 12 hours after injection, which was maintained until 72 hours after injection. In contrast, Cy5.5 signal was concentrated at the injection site in the CM injection at all time points. Conclusion : These data suggested that the LV might be suitable for preclinical injection route of therapeutics targeting the spinal cord to test their treatment efficacy and biosafety for spinal cord diseases in small animal models.

• Journal of Ocean Engineering and Technology
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• v.13 no.3B
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• pp.38-46
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• 1999

Increasing stringent emissions legislation and requirement of more effective energy used for diesel engine demand the fine control of the fuel injection system. Recently, the electromagnetic fuel injection control system for diesel engine is tried to realize the optimum diesel combustion by the feel back sensing as optical signal of combustion flame. The photo detectors were made for the feed back signal of electromagnetic fuel injection control for small DI diesel engine. Their abilities to detect defining combustion events were examined. By evaluating test results, it was shown that the wider acceptable optical range design of optical probe window face, and selection of installation position and installation method of detector were important point for improving sensing ability. The detector was shown to detect start and end of diffused combustion and maximum point of flame intensity impossible for pressure sensor, and also shown that the maximum point of flame intensity was 75% of accumulated heat release point within the experimental conditions.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2006.05a
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• pp.81-85
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• 2006

In this study, we have been examined nano Injection Molding process which can improve transcription of 100nm-level pattern. We changed the various parameter (temperature of injection mold, clamp force, temperature of nozzle) which can be influence for improving transcription. And we measured and analyzed shapes of 100nm-level pattern by Automic Force Microscope for proving transcription. We made the Blu-ray Disc sample for proving transcription. And we measured HF-Signal and jitter. As a result, when the temperature of mold is more than $120^{\circ}C$ and the clamp force is more than 10 ton, We reached over 95 percent of transcription compared with stamper pattern. And we reached in-spec. value for HF-Signal and Jitter. Then we reached over 95 percent of transcription compared with stamper pattern.

• Transactions of the Korean Society of Automotive Engineers
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• v.3 no.6
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• pp.134-144
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• 1995

The solenoid actuated hydrogen injector and the capacitive peak-hold type driving circuit were designed and made, and the hydrogen supply system for in-cylinder injection was constructed with these. The performance of the injector was investigated through measuring the pintle lift profiles and the injection quantities, and the performance of the hydrogen supply system was confirmed through the experiments at the single cylinder engine. The injection quantity increased linearly as the duration of driving signal increased. At the single cylinder engine, the hydrogen injector was operated stably. The hydrogen flow rate of the injector with the peak-hold type driving circuit could be controlled precisely at high engine speed or low load condition only with the variation of signal duration.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.22 no.8
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• pp.1622-1631
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• 1997

A 3-stages Active Microstrip Phased Array Antenn(AMPAA) is implemented using Injection-Locking Coupled Oscillators(ILCO). The AMPAA is a beam scanning active antenna with capability of electrical scanning by frequency varation of ILCO. The synchronization of resonance frequencies in array elements is occured by ILCO, and the ILCO amplifies the injection signal and functions as a phase shifter. The microstrip ptch is operated as a radiation element. The unilateral amplifier is a mutual coupling element of AMPAA, eliminates the reverse locking signal and controls the locking bandwidth of ILCO. The possibility of Monolithic Microwave Integrated Circuits(MMIC) of T/R module is proposed by simplified and integrated fabrication process of AMPAA. The 0.75.$lambda_{0}$ is fixed for a mutual coupling space to wide the scanning angle and minimize the multi-mode. The AMPAA has beam scanning angle of 31.4.deg., HPBW(Half Power Beam Widths) of 26.deg., directive gain of 13.64dB and side lobe of -16.5dB were measured, respectively.

• Investigative Magnetic Resonance Imaging
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• v.6 no.2
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• pp.158-165
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• 2002

Purpose : To evaluate the effect of Gd-DTPA on signal intensity of diffusion-weighted magnetic resonance(MR) image and apparent diffuse coefficient (ADC) in dog brain with hype racute stroke. Materials and methods : Experimental canine model of hyperacute cerebral infarction was made by selective intraarterial embolization with particulate embolic material. Diffusion-weighted MR imaging was performed in five dogs at 1 hour after the embolization of internal carotid artery. After intravenous bolus injection of Gd- DTPA, additional 11 diffusion-weighted MR images were serially obtained from 2 minutes to 90 minutes after injection in each dog. The author evaluated findings of hyperacute cerebral infarction on diffusion-weighted MR imaging, and calculated mean signal intensity and mean ADC in infarcted region and contralateral normal region. Statistical analysis of mean signal intensity, mean ADC and contrast-noise ratio before and after Gd-DTPA injection was performed. Results : Hyperacute cerebral infarction developed in all five dogs on diffusion-weighted MR images obtained 1 hour after embolization. The area of hyperacute infarction had steady increase in signal intensity on diffusion-weighted MR image and decrease in ADC. In normal perfusion area, decrease in signal intensity was observed at 2 minutes the Gd-DTPA injection, whereas ADC did not changed. Conclusion : Intravenous injection of Gd-DTPA had no influence on ADC in both hyperacute infarction and normally perfused are a, but caused initial transient signal reduction in normally perfused area on diffusion-weighted MR image due to susceptibility effect of Gd-DTPA. It is important to calculate ADC in evaluating the effect of diffusion after injection of Gd-DTPA.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.10 no.5
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• pp.653-662
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• 1999

In this paper, subharmonically injection locked oscillator(SILO) was designed and measured. SILO with series feedback was designed using Two Signal Method(TSM). The free-running oscillator frequency was 9.4 GHz with 6 dBm output power. In case of injection, the multiplied injected signal locked the free-running frequency. The locked signal output power was higher than any other spurious response at least 40 dB. The locking range was 220MHz (second subharmonic locking), 100 MHz(4th subharmonic locking), and phase noise was -111 dBc/Hz, -104 dBc/Hz at 100kHz offset, respectively.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.49 no.5
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• pp.338-344
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• 2000

This paper proposes a field-oriented control strategy without speed sensor in overall speed range. At low speed region including zero speed, the electrical saliency which is due to the main flux saturation is used in order to estimate an instantaneous flux position. This electrical saliency can be obtained from the difference of high frequency impedance by the high frequency signal injection. This method enables the stable operation at zero speed or stator frequency even under heavily loaded condition. However, because of the high frequency signal injection the loss and noise in motor increase and the voltage margin is reduced as the motor speed increases. Therefore, this algorithm must be supplemented with the algorithm based on the electrical model of motor, which is conventionally used in the region except the low speed. This paper proposes the combination algorithm between the high frequency signal infection method and the adaptive observer, in which the rotor flux and motor speed can be simultaneously estimated by the adaptive control theory. This combination algorithm enables the stable operation of field-oriented speed control without speed sensor in overall speed range. This is verified by experimental results.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.47 no.8
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• pp.99-107
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• 2010

In a single frequency network (SFN) for Advanced Television Systems Committee (ATSC) terrestrial digital television (DTV) system, the interferences induced by the multiple transmitters and/or repeaters using the same frequency are inevitable. Since the presence of interferences results in performance degradation of the SFN, it is crucial to manipulate the interferences by adjusting the transmit power and timing of each transmitter and repeater. In the ATSC terrestrial DTV system, in order to facilitate the interference manipulation process, a transmitter identification (TxID) signal which is uniquely embedded in the signal to be transmitted from each transmitter and repeater is recommended. Even though the injection level of the TxID signal is much lower than the DTV signal, the TxID signal injection infects the DTV signal. Hence, the effect of the TxID signal on the DTV signal must be investigated before deployment. In this paper, the effect of the TxID signal on the performance of legacy DTV receivers under additive white Gaussian noise and multipath channel environments is investigated not only with computer simulation but also with laboratory and field tests. The test results show that the average threshold of visibility degradation of the legacy DTV receivers due to the TxID signal injection is less than 0.2 dB at the TxID injection level of -30 dB.

• 제어로봇시스템학회:학술대회논문집
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• 2000.10a
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• pp.24-24
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• 2000

This paper proposes a design method of sliding mode observer for SISO linear systems with a disturbance input. We first construct an observer with a constant gain matrix, a feedforward injection map and an external feedforward compensation signal input. Using the second Lyapunov method, we present a sufficient condition for the existence of sliding mode observer. The proposed observer guarantees that the state error trajectories enter a certain region in finite time and remain inside thereafter.