• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.11 no.5
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• pp.145-150
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• 2011

This study was developed the posture balance system of multi-parameter for moving body after and before exercising. Body transition meaned a head moving and upper body moving. This system has catched a signal for physical condition of body data such as a data acquisition system, data signal processing and feedback system. There were checked a parameter that measured vision, vestibular, somatosensory, CNS. This system was evaluated a data through the stability. The posture balance system can be used to support assessment for body moving in exercising situation. It was expected to monitor a physical parameter for health management system.

• International Journal of Highway Engineering
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• v.15 no.4
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• pp.135-146
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• 2013

PURPOSES : This study aimed to analyze the impact the operation of pre-signals at 4-leg signalized intersections and present primary environmental factors of roads that need to be considered in the installation of pre-signals. METHODS : Shift of proportions safety effectiveness evaluation method which assesses shifts in proportions of target collision types to determine safety effectiveness was applied to analyze traffic crash by types. Also, Empirical Bayes before/after safety effectiveness evaluation method was adapted to analyze the impact pre-signal installation. Negative binomial regression was conducted to determine SPF(safety performance function). RESULTS : Pre-signals are effective in reducing the number of head on, right angle and sideswipe collisions and both the total number of personal injury crashes and severe crashes. Also, it is deemed that each factor used as an independent variable for the SPF model has strong correlation with the total number of personal injury crashes and severe crashes, and impacts general traffic crashes as a whole. CONCLUSIONS: This study suggests the following should be considered in pre-signal installation on intersections. 1) U-turns allowed in the front and rear 2) A high number of roads that connect to the intersection 3) Many right-turn traffic flows 4) Crosswalks installed in the front and rear 5) Insufficient left-turn lanes compared to left-turn traffic flows or no left-turn-only lane.

• Journal of Biomedical Engineering Research
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• v.26 no.3
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• pp.177-184
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• 2005

In this paper, we proposed a new hearing aid algorithm to improve SNR(signal to noise ratio) of noisy speech signal and speech perception. The proposed hearing aid algorithm is a multi-band loudness compensation based independent component analysis (ICA). The proposed algorithm was compared with a conventional spectral subtraction algorithm on behind-the-ear type hearing aid. The proposed algorithm successfully separated a target speech signal from background noise and from a mixture of the speech signals. The algorithms were compared each other by means of SNR. The average improvement of SNR by ICA based algorithm was 16.64dB, whereas spectral subtraction algorithm was 8.67dB. From the clinical tests, we concluded that our proposed algorithm would help hearing aid user to hear clearly a target speech in noisy conditions.

• Journal of Magnetics
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• v.18 no.4
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• pp.422-427
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• 2013

The aim of this study was to investigate effects of the number of acquisitions (NEX) on signal-to-noise (SNR) and artifacts in SENSE parallel imaging of magnetic resonance imaging (MRI). 3.0T MR System, 8 Channel sensitivity encoding (SENSE) head coils were used along with an in-vivo phantom. Reference sequence of 3D fast field echo (FFE) was consisted of NEX values of 2, 4, 6, 8, 10 and 12. The T2 turbo spin echo (TSE) sequence used for exams achieved SENSE factors of 1.2, 1.5, 1.8, 2.0, 2.2, 2.5, 2.8, 3.0, 3.2, 3.5, 3.8 and 4.0. Exams were conducted five times for each SENSE factor to measure signal intensity of the object, the posterior phase-encode direction and frequency direction. And SNR was calculated using mean values. SENSE artifacts were identified as background signal intensity in the phase-encoded direction using MRIcro. It was found that SNR increased but SENSE artifacts reduced with NEX of 4, 8 and 12 when the NEX increased in reference scan. It is therefore concluded that image quality can be improved with NEX of 4, 8 and 12 for reference scanning.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.35 no.5
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• pp.287-293
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• 2009

Cell survival is the result of a balance between programmed cell death and cellular proliferation. Cell membrane receptors and their associated signal transducing proteins control these processes. Of the numerous receptors and signaling proteins, epidermal growth factor receptor (EGFR) is one of the most important receptors involved in signaling pathways implicated in the proliferation and survival of cancer cells. EGFR is often highly expressed in human tumors including oral squamous cell carcinomas, and there is increasing evidence that high expression of EGFR is correlated with poor clinical outcome of common human cancers. Therefore, we examined the antiproliferative activity of gefitinib, epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKI), in head and neck cancer cell lines. SCC-9, KB cells were cultured and growth inhibition activity of gefitinib was measured with MTT assay. To study influence of gefitinib in cell cycle, we performed cell cycle analysis with flow cytometry. Western blot was done to elucidate the expression of EGFR in cell lines and phosphorylation of EGFR and downstream kinase protein, Erk and Akt. Significant growth inhibition was observed in SCC-9 cells in contrast with KB cells. Also, flow cytometric analysis showed G1 phase arrest only in SCC-9 cells. In Western blot analysis for investigation of EGFR expression and downstream molecule phosphorylation, gefitinib suppressed phosphorylation of EGFR and downstream protein kinase Erk, Akt in SCC-9. However, in EGFR positive KB cells, weak expression of active form of Erk and Akt and no inhibitory activity of phosphorylation in Erk and Akt was observed. The antiproliferative activity of gefitinib was not correlated with EGFR expression and some possibility of phosphorylation of Erk and Akt as a predictive factor of gefitinib response was emerged. Further investigations on more reliable predictive factor indicating gefitinib response are awaited to be useful gefitinib treatment in head and neck cancer patients.

• Korean Journal of Otorhinolaryngology-Head and Neck Surgery
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• v.61 no.12
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• pp.663-668
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• 2018

Background and Objectives The main objectives of this study were to determine the clinical usefulness of the program-assisted and real ear measurement (REM)-assisted fitting of hearing aids. Subjects and Method Fifteen participants with moderate to moderately severe hearing loss were enrolled in this study. Objective and subjective fitting results were assessed to compare the benefits between the program-assisted fitting (using a software fitting program) and the REM-assisted fitting. Real ear insertion gain (REIG), sound-field audiometry using warble tone, and Korean Hearing in Noise Test (K-HINT) were performed as objective tests. Sound quality rating was performed as a subjective test. Results In the program fitting, 48.89% of fitting points failed to come within ${\pm}10dB$ of the REIG target. In the REM fitting, however, the percentage of failure significantly decreased to 23.33% (p=0.013). In K-HINT test, the reception threshold for speech in quiet situation significantly decreased from 50.1 dB HL with the program fitting to 44.7 dB HL after the REM fitting (p<0.001). In front noise condition, signal-to-noise ratio improved from 4.53 dB to 3.50 dB with the REM fitting without statistical significance (p=0.099). In the sound quality rating, the REM fitting ($4.27{\pm}0.56$) showed a significantly better sound quality ratings than the program fitting ($3.69{\pm}0.74$) (p=0.017). Conclusion The REM fitting showed better results in both subjective and objective measurements than the program fitting.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.47 no.5
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• pp.388-396
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• 2019

This paper describes the RF(Radio Frequency) interference on the GNSS receiver due to the S-band signals transmitted from the transmitters in the Test Launch Vehicle, and analyzes the cause of the RF interference. Due to the S-band signals that have relatively high power levels compared with GNSS signals, an LNA(Low Noise Amplifier) in the active GNSS antenna was saturated, and the intermodulation signal within GNSS in-bands was produced in the LNA whenever two S-band signals were received from the GNSS antenna. For these reasons, the C/N0 of the satellite signals in the GNSS receiver was attenuated severely. The design of the LNA was changed in order to protect the RF interference due to the S-band signals and the suppression capability of the RF interference was confirmed in the new LNA through the comparison of the old LNA.

• Journal of Marine Life Science
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• v.3 no.2
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• pp.45-50
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• 2018

Rock bream iridovirus (RBIV) is a megalocytivirus widely infected in various fish species in Korea, causing symptoms of acute inflammation and enlargement of spleen. In our previous study, RBIV induced the initial upregulation but later down-regulation of proinflammatory cytokines and IFN1 gene expression. Signal transducers and activators of transcriptions (STAT) are transcription factors involved in the regulation of immune genes including IFNs. This study was conducted to analyse the expression of STAT2. The expressional study of STAT2 gene was performed in head kidney and spleen upon RBIV infection and immune stimulants like LPS or poly I:C in vitro. Consequently, STAT2 gene expression pattern was different in head kidney and spleen as it was significantly up-regulated by LPS from 4 h to 8 h but down-regulated at 24 h while up-regulated by poly I:C at 8 h in head kidney while, in spleen, STAT2 gene expression was down regulated by LPS but significantly up-regulated by poly I:C. Upon RBIV stimulation, STAT2 gene expression was significantly down-regulated by high dose RBIV at 4 h but up-regulated at 8 h and 24 h in head kidney. In spleen cells, it was up-regulated by medium dose RBIV at 4 h and by high dose RBIV at 4 h and 8 h but down regulated later then. In vivo, STAT2 gene expression was not significantly affected by RBIV infection while significant up-regulated by vaccination at day 7 post-vaccination, indicating STAT2 gene can be involved in adaptive immune response in rock bream.

• Journal of radiological science and technology
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• v.46 no.4
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• pp.295-301
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• 2023

In addition to protocol adjustments during CT examinations, the height of the CT table can also affect image quality. Therefore, this study aimed to investigate the change in image quality depending on the height of the table in brain CT, which accounts for a large proportion of CT examinations, by measuring signal to contrast to noise ratio (CNR) and noise power spectrum (NPS) using the head phantom and evaluating them. The head phantom images were acquired using Philips Brilliance iCT 256. When the image was acquired, the table height was adjusted to 815, 865, 915, 965, 1015, and 1030 mm, respectively, and each scan was performed 3 times for each height. The CNR result showed the highest value at 965 mm, which is the height adjacent to the center of the head phantom. NPS showed the lowest NPS at 915 mm, the center of the head phantom in the low frequency region. From these results, it can be seen that the height of the table in CT examination is closely related to the image quality, and it can be seen the characteristics of image quality according to CT table through quantitative evaluation methods such as CNR and NPS.

• Journal of the Korea institute for structural maintenance and inspection
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• v.23 no.7
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• pp.129-136
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• 2019

In this study, the magnetic flux leakage technique was applied to diagnose steel plate damage, imaging technique was applied through those signals. Steel plate specimens with different thicknesses were prepared for the imaging the magnetic flux leakage signal, and 6 different depths of damage were artificially processed at the same locations on each specimen. The sensor head consist hall sensor and magnetization yoke was fabricated to magnetize the steel plate specimen and measure the magnetic flux leakage signal. In order to remove the noise and increase the resolution of the image in the signal collected from the hall sensor, various of signal processing was performed. P-P value was analyzed for each channel to analyze the magnetic flux leakage signals measured from each damaged part. Based on the above processed signals and analysis, it was converted into heatmap image. Through this, it was possible to identify the damage on the steel plate at glance by imaging magnetic flux leakage signal.