• Journal of Plant Biotechnology
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• 제35권1호
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• pp.75-80
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• 2008

마늘의 경정을 기내배양하여 대량의 기내종구를 생산하기 위한 다신초의 유기 및 기내구의 비대조건을 찾고자 배지의 당의 농도를 다르게 하고 또한 생장조절물질을 첨가하여 신초의 대량발생 여부를 확인하였으며, 대형배양용기를 이용하여 대량생산을 하기 위한 tank배양에서 신초의 분화와 기내구의 발달에 관하여 검토하였다. 경정배양에서의 shoot 발생이나 기내구 형성 모두 3% sucrose 첨가 MS고체배지에서 8% 보다 양호하였으며, 생장조절물질의 효과는 2 mg/L 2iP와 0.2 mg/L IAA의 혼합처리에서 shoot 발생과 bulb의 형성수가 양호하였다. 이 처리구에서 발생한 shoot와bulb의 수는 각각 3.3 및 2.7개로 나타났다. 다신초를 유도할 수 있는 조건의 배지에서 경정을 2개월 동안 배양하여 다신초를 분화시킨 후, 20 L water tank를 이용하여 sucrose 농도를 3%와 8%로 설정한 MS액체배지에 옮겨 45일간 배양한 후에 bulb형성을 조사하였을 때 유식물체의 생육에 있어서는 3% sucrose 첨가조건에서 8% 첨가배지보다 양호하였다. 그러나 기내구의 형성이나 생장에 있어서는 sucrose의 농도가 8%일 때 보다 효과적이었다. 경정배양에서의 다신초의 초기생산에는 3% sucrose조건에서 양호한 효과를 보이고 있으므로 마늘의 인경구를 대량으로 생산하기 위해서는 다신초의 생산과 구비대 과정을 구분하는 2단계 배양법을 도입하는 것이 유리할 것이다. Tank배양시 배지에 0.2 mg/L BA, 0.02 mg/L NAA를 첨가한 처리에서 양호하였으며 NAA 농도가 높을 수록 유식물체의 생육이나 구비대의 효과는 현저하게 저하되었다.

• 정보처리학회논문지B
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• 제14B권6호
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• pp.453-460
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• 2007

본 논문은 정형화되지 않은 텍스트 라인들을 추출하기 위한 방법을 보여주고 있다. 텍스트 라인들은 각기 다른 각도로 구성되고, 심하게 굴곡이 있는 모양, 그리고 텍스트 라인내의 약간의 단어 사이의 공간이 생기게 된다. 그러한 텍스트 라인들은 포스터, 주소, 그리고 예술 문서 등에서 발견된다. 제안하는 방법은 기존의 직관적인 그룹핑 방법에 기반을 두고 있지만, 하나의 라인에서 발생하는 불충분한 특징점들과 모호한 회전 등을 극복하기 위한 방법을 개발하였다. 본 논문에서 텍스트 라인들은 몇 개의 연결된 성분들로 구성되고, 이 성분들은 하나의 문자 또는 연결된 문자들의 검은색 화소들의 집합이라고 가정하였다. 제안하는 방법은 반복적으로 증가되는 임계값과 가까운 성분들은 하나의 체인으로 병합하게 되고 확장되어 길어진 체인들은 라인의 원시 체인으로서 인지된다. 그때 원시 체인들은 텍스트 라인의 부분적 회전에 따라 좌우로 확장되어 진다. 텍스트 라인의 부분적인 회전은 원시 체인이 확장될 때, 체인들의 각 면에서 재구성될 것이다. 이러한 과정을 통해서 모든 텍스트 라인들이 구성되어 진다. 제안 방법은 로고와 슬로건에서 사용된 곡면으로 쓰여진 텍스트 라인들에 대해서 실험한 결과 직선 텍스트 라인은 98%, 곡선 텍스트 라인은 94%로서 높은 추출율을 보여주고 있다.

• Journal of Biosystems Engineering
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• 제39권3호
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• pp.205-214
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• 2014

Purpose: Phytosanitary irradiation treatment can effectively control regulated pests while maintaining produce quality. The objective of this study was to establish the best irradiation treatment for mangosteen, a popular tropical fruit, using a Monte Carlo simulation. Methods: Magnetic resonance image (MRI) data were used to generate a 3-D geometry to simulate dose distributions in a mangosteen using a radiation transport code (MCNP5). Microsoft Excel with visual basic application (VBA) was used to divide the image data into seed, flesh, and rind. Radiation energies used for the simulation were 10 MeV (high-energy) and 1.35 MeV (low-energy) for the electron beam, 5 MeV for X-rays, and 1.25 MeV for gamma rays from Co-60. Results: At 5 MeV X-rays and 1.25 MeV gamma rays, all areas (seeds, flesh, and rind) were irradiated ranging from 0.3 ~ 0.7 kGy. The average doses decreased as the number of fruit increased. For a 10 MeV electron beam, the dose distribution was biased: the dose for the rind where the electrons entered was $0.45{\pm}0.03$ kGy and the other side was $0.24 {\pm}0.10$ kGy. Use of an electron kinetic energy absorber improved the dose distribution in mangosteens. For the 1.35 MeV electron beam, the dose was shown only in the rind on the irradiated side; no significant dose was found in the flesh or seeds. One rotation of the fruit while in front of the beam improved the dose distribution around the entire rind. Conclusion: These results are invaluable for determining the ideal irradiation conditions for phytosanitary irradiation treatment of tropical fruit.

• 센서학회지
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• 제22권2호
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• pp.130-135
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• 2013

This study proposed a noble process to fabricate TSV (Through Silicon Via) structure which has lower cost, shorter production time, and more simple fabrication process than plating method. In order to produce the via holes, the Si wafer was etched by a DRIE (Deep Reactive Ion Etching) process. The via hole was $100{\mu}m$ in diameter and $400{\mu}m$ in depth. A dielectric layer of $SiO_2$ was formed by thermal oxidation on the front side wafer and via hole side wall. An adhesion layer of Ti and a seed layer of Au were deposited. Soldering process was applied to fill the via holes with solder paste and metal powder. When the solder paste was used as via hole metal line, sintering state and electrical properties were excellent. However, electrical connection was poor due to occurrence of many voids. In the case of metal powder, voids were reduced but sintering state and electrical properties were bad. We tried the via hole filling process by using mixing solder paste and metal powder. As a consequence, it was confirmed that mixing rate of solder paste (4) : metal powder (3) was excellent electrical characteristics.

• Journal of Radiation Protection and Research
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• 제49권3호
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• pp.102-113
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• 2024

Diffusing alpha-emitters radiation therapy (DaRT) represents a groundbreaking development in cancer therapy, offering a solution to the limitations of conventional radiation therapy. By deploying ²²⁴Ra embedded seeds, DaRT achieves targeted delivery of high-dose alpha particles directly to tumor sites, showing considerable efficacy in tumor control and minimal damage to adjacent healthy tissues. This comprehensive review analyzes the published literature regarding mechanisms, seed production, dose calculation, measurement, and biological experiments related to DaRT. It includes in-depth discussions on mathematical models, Monte Carlo simulations for dose distribution, real-time in vivo dosimetry developments, and biological experiments both in vitro and in vivo. Clinical trial outcomes are also examined to evaluate the therapy's effectiveness in various cancer types. DaRT utilizes ²²⁴Ra-labeled seeds, using the decay chain of ²²⁴Ra to deliver alpha particles effectively within a tumor. Several asymptotic diffusion-leakage models were developed to calculate the alpha dose distribution of DaRT. In vivo dosimetry techniques have been developed for real-time monitoring. Biological experiments demonstrated the cytotoxic effects of DaRT across various cancer cells, with varying radiosensitivity. Additionally, the enhanced effects of combined therapy with chemotherapy and immunotherapy were suggested by many in vivo studies. Clinical trials have shown high complete response rate in squamous cell carcinoma, with minimal side effects, suggesting DaRT's feasibility and safety. DaRT emerges as a highly localized cancer treatment method with minimal side effects compared to traditional radiation therapy. It directly ablates tumors and potentially enhances immune responses, indicating a significant advance in cancer therapy. Future research and ongoing clinical trials will further elucidate its efficacy across different cancer types and in combination with other treatments.

• 한국결정성장학회지
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• 제8권1호
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• pp.1-9
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• 1998

본 연구에서는 냉각매체로서 물을 이용하는 수정된 열교환법을 이용하여 45$\times$45$\times$20(mm) 크기의 사각단면 형상의 sapphire 단결정의 제조가능 조건에 대하여 조사하였다. 온도에 따른 성장로 내의 압력 변화로부터 사파이어의 용융 및 응고 과정을 추적할 수 있었으며, 이로부터 sapphire 단결정은 1970~$1960^{\circ}C$에서 응고가 완료됨을 알 수 있었다. 도가니 성형시 이루어지는 '귀'의 형태는 도가니 벽면과 접촉되지 않는 '나선형태'이어야 한다. 열유출부는 융액 내의 온도구배를 지배하며 융액내의 열유속과 씨앗 결정의 흔적은 Mo 봉의 체적 변화로서 조절할 수 있었다. 기공 형성을 억제하기 위해서는 $0.2^{\circ}C$/min 이하의 발열체의 냉각속도가 요구되었다.

• Mycobiology
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• 제30권4호
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• pp.233-239
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• 2002

The main aim of this study is to evaluate the efficiency of two biologically active compounds(Strom and F-760) in control of wheat root rot disease and its causal organisms. Fusarium graminearum, F. oxysporum, F. solani and Bipolaris sorokiniana were used as target organisms. In vitro, the two compounds showed fungicidal effect on all investigated pathogens resulted in suppression of radial growth and mycelial dry weight of them. Under greenhouse conditions, treatment of wheat grains with either Strom or F-760 before cultivation significantly reduced the percent of disease distribution as well as the mean disease rating of plants in both seedling and flowering stages. Fresh and dry weights of plants as well as water maintenance capacity were increased as the result of applying these compounds as seed dressing. Also data showed that the membrane stability of plants was injured as a result of infection with all investigated organisms, while this injury was alleviated when F-760 and Strom were applied. The $K^+$ efflux and the leakage of UV absorbing metabolites was stimulated with fungal infection. However, F-760 and Storm treatment partially retarded the stimulatory effect on leakage of $K^+$ and UV-absorbing metabolites of fungal infected plants. On the other side, the fungal infection had inhibitory effects on pigment fractions(chlorophyll a, b, and carotenoids) biosynthesis in wheat leaves. This retarding effect was partially or completely alleviated as the grains were treated with the applied compounds.

• 한국결정성장학회:학술대회논문집
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• 한국결정성장학회 1996년도 The 9th KACG Technical Annual Meeting and the 3rd Korea-Japan EMGS (Electronic Materials Growth Symposium)
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• pp.519-521
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• 1996

Emerald (3BeO.Al2O3.6SiO2 : Cr3+) single crystals were crystals were grown by reflux method of temperature gradient in the flux solution of Li2O-MoO3-V2O5 system. The composition of flux materials were 3 mole ratio of MoO3-V2O5/Li2O, subtituted 0.2 mole% of K2O, Na2O, Nb2O5 etc to Li2O content, solved 10-15% of beryl to flux quantity and doped 1% of Cr2O3 to emerald amount. Those of mixing were melted at 110$0^{\circ}C$ in Pt containers of the 3 zone furnace of melt-growth-return to circulate continniously, specially it has been grown large emerald single crystal when thermal fluctuation was treated for 2hrs of once time a day at 1050-95$0^{\circ}C$ in growth zone, substitutional solid solution effect of Cr+3 ion for Al+3 to the growth of emerald single crystal was good. Emerald single crystals were c(0001) hexagonal crystal face of preferencial growth direction and m(1010) post side. When it had been durated for 5 months emerald single crystals of the firet size of 0.6mm thickness of seed crystal were grown 32$\times$65mm(c x m) of maximum size and 6.2mm thickness.

• 천문학회보
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• 제37권1호
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• pp.91.1-91.1
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• 2012

지구 자기권의 입자분포는 지구 자기권의 상태와 태양풍의 물리적 상황에 따라 다르다. 가령, 정지궤도에서 고에너지 입자의 flux가 낮아지는 것이 관측된다. 이러한 flux dropout 기간은 대부분 storm main phase에 해당된다. 반면 태양풍의 속력이 상대적으로 높은 HSS(high speed stream)기간 동안에는 대부분 정지궤도에서의 고에너지 입자 flux가 높아지며 radiation belt의 고에너지 입자들의 seed electron 역할을 할 것으로 예상하고 있다. 본 연구에서는 GOSE 11 위성의 electron flux data와 태양풍의 속도를 이용하여 HSS, quiet time, flux dropout 기간을 정의 하였다. 또한, 지구로부터 7~8Re 떨어진 night side지역을 radiation belt의 trapping boundary 바로 바깥 경계지역과 같다고 가정하였다. 그리고 각 기간 동안 이 경계지역에서 입자들의 분포와 관련된 물리적 조건을 결정하는 것을 목표로 하였다. 이는 방사선 벨트 내부에서의 역학적 진화에 영향을 미칠 수 있다. 2007년 6월부터 2010년 8월까지 이러한 경계지역에 THEMIS 위성이 위치했을 때 ESA와 SST의 omni-directional flux를 이용하여 에너지에 대한 입자플럭스 분포 함수를 산출하였다. 또한 각 기간에 평균한 분포 함수를 가장 잘 나타낼 수 있는 해석적 함수를 도출하였다. 추가로, 경계지역에서의 입자들의 pitch angle 분포 패턴도 결정 하였다. 이 결과는 방사선 벨트의 전산모사에서 실질적인 경계 조건으로 사용될 수 있다.

• Journal of Mechanical Science and Technology
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• 제18권2호
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• pp.313-324
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• 2004

A rich phenomenon in the dynamics of azimuthal vortices in a circular cylinder caused by the inertial oscillation is investigated numerically at high Reynolds numbers and moderate Rossby numbers. In the actual spin-up flow where both the Ekman circulation and the bottom friction effects are included, the first appearance of a seed vortex is generated by the Ekman boundary-layer on the bottom wall and the subsequent roll-up near the corner bounded by the side wall. The existence of the small vortex then rapidly propagates toward the inviscid region and induces a complicated pattern in the distribution of azimuthal vorticity, i.e. inertial oscillation. The inertial oscillation however does not deteriorate the classical Ekman-pumping model in the time scale larger than that of the oscillatory motion. Motions of single vortex and a pair of vortices are further investigated under a slip boundary-condition on the solid walls. For the case of single vortex, repeated change of the vorticity sign is observed together with typical propagation of inertial waves. For the case of a pair of vortices with a two-step profile in the initial azimuthal velocity, the vortices' movement toward the outer region is resisted by the crescent-shape vortices surrounding the pair. After touching the border between the core and outer regions, the pair vortices weaken very fast.