• Asian Pacific Journal of Cancer Prevention
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• v.17 no.7
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• pp.3077-3084
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• 2016

Various beneficial effects have been described for fermented papaya preparation (FPP: SAIDO-PS501) based on its anti-oxidative and anti-inflammatory functions. The present study was designed to determine the effects of FPP on carcinogenesis in vivo, and immunomodulatory function in vitro. Mice were injected with RL male 1 cells subcutaneously or 3-methylcholantherene (MCA) intravenously to induce cancer and orally or intraperitoneally treated with FPP solution. Human peripheral blood mononuclear cells (PBMC) were obtained from healthy volunteers and patients with atopic dermatitis, treated with FPP, and subjected to measurement of cytokine production and changes in Foxp3-expressing regulatory T cell (Treg) stimulated with phytohemagglutinin (PHA). Administration of FPP suppressed tumor size and the incidence of malignancy. In vitro, treatment of PBMC with FPP induced IL-$1{\beta}$, $TNF{\alpha}$ and $IFN{\gamma}$ production. Moreover, FPP suppressed proliferation of PHA-stimulated Foxp3-expressing Treg. These results suggest that FPP has chemotherapeutic properties.

• Asian Journal for Public Opinion Research
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• v.1 no.1
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• pp.7-25
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• 2013

For the Palestinians, what is the impact of the Arab Spring? The revolution not only dislodged Mubarak from the presidency, but also changed Egyptian policy regarding Palestinians in Gaza. New Egyptian diplomacy has encouraged Hamas and Fatah, which had been in dispute, to seek reconciliation and has loosened the border control on humanitarian grounds. We focus on Palestinian voting attitudes in the wake of the Arab Spring. Despite the vast quantity of literature written about Palestinian politics since the first decade of the millennium, we know little about the determinants of Palestinian attitudes toward the divided governments in the West Bank and the Gaza Strip. The Fatah government, in the West Bank, increased in popularity after submitting a request for UN recognition of Palestinian statehood. In Gaza, the Hamas government lost popularity because of mismanagement but won support through the success of its prisoner swap deal with Israel. However, evaluation of the ruling party does not depend only on one-time events. This research attempts to measure the impact of policy change in Gaza after the Arab Spring. We provide an account of our research on Palestinian attitudes toward the divided governments based on two sets of the original survey data conducted in May 2009 and June 2012. The paper sheds light on Palestinian attitudes and makes clear the effects of "democratization" in the Middle East and the effects of regional context factors on the occupied Palestinians.

• Agricultural and Biosystems Engineering
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• v.4 no.1
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• pp.1-7
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• 2003

Internal defects such as browning of the flesh and blackening and rot of the ovary of pear can be easily developed because of the inadequate environmental conditions during the storage and distribution of fruit. The quality assurance system for the agricultural product is to be settled in Korea. All defected agricultural products should be excluded prior to the distribution to enhance the commercial values. However, early stage on-line defect detection of agricultural product is very difficult and even more difficult in a case of the internal defects. The goal of this research is to develop a system that can detect and classify internal defects of agricultural produce on-line using VIS/NIR transmittance spectroscopy. And Shingo pear, which is one of the famous species of Korean pear, was used for the experiment. Soft independence modeling of class analogy (SIMCA) algorithm was employed to analyze the transmittance spectroscopic data qualitatively. On-line classification system was constructed and classification model was developed and validated. As a result, the correct classification rate (CCR) using the developed classification model was 96.1 ％.

• Proceedings of the Materials Research Society of Korea Conference
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• 2012.05a
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• pp.56.1-56.1
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• 2012

The microstructures and mechanical properties of Co-29Cr-6Mo alloy with C and N additions, produced by additive manufacturing using electron beam melting (EBM) method, were studied using X-ray diffraction, electron back scatter diffraction, transmission electron microscope, Vickers hardness tests, and tensile tests, focusing on the influences on the build direction and the various heat treatments after build. It is found that the microstructures for the as built specimens were changed from columnar to equiaxed grain structure with average grain size of approximately $10-20{\mu}m$ due to the heat treatment employing the reverse transformation from a lamellar (hcp + $Cr_2N$) phase to an fcc. Our results will contribute to the development of biomedical Ni-free Co-Cr-Mo-N-C alloys, produced by EBM method, with refined grain size and good mechanical properties, without requiring any hot workings.

• Korean Journal of Plant Taxonomy
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• v.47 no.1
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• pp.1-5
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• 2017

The population status of Hydrangea luteovenosa Koidz. in Korea was investigated, with an emphasis on its genetic diversity. From field surveys, we obtained the only locality record for a wild population in Jeju Island, which contained 285 individuals in total. Genotyping was performed using five microsatellite markers for the all extant plants in Korea. Three Japanese populations were also genotyped for the comparative analyses. The genotyping result showed that the Jeju population consisted of only two multilocus genotypes, including identical heterozygous genotypes at two loci; it had been maintained mostly by vegetative reproduction; and although the Jeju population is geographically far from Japanese populations, all alleles observed in the Korean population were shared with Japanese populations, suggesting the possibility that H. luteovenosa in the Jeju Island had been recently migrated or introduced from Japan. Future ecological and genetic studies associated with negative effects of low genetic variation will be essential for determining the conservation direction of the threatened Korean population of this species.

• Journal of Radiation Protection and Research
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• v.41 no.4
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• pp.436-441
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• 2016

Background: Although nuclear disaster is considered rare, its effects are serious, and we must prepare a system to enable an effective response. Materials and Methods: Since 2010, we have been offering a two-day seminar to provide current nurses and radiological technologists with basic knowledge and train them in radiation emergency medicine (REM) techniques. This training offers lectures to deepen each specialty from the perspective of REM, as well as exercises on ways to handle irradiated and/or contaminated patients. Participants were expected to treat patients according to the concept of REM. Results and Discussion: All participants learn to assess and decontaminate contaminated wounds through drills. The questionnaire survey for participants indicated that participants were satisfied with this training and wanted to attend again. Conclusion: We believe that this training course will provide a valuable opportunity for medical professionals to gain knowledge and expertise in REM.

• International Journal of Naval Architecture and Ocean Engineering
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• v.11 no.1
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• pp.44-51
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• 2019

Designing sophisticate ship structures that satisfy several design criteria simultaneously with minimum weight and cost is an important engineering issue. For a ship structure composed of a shell and stiffeners, this issue is more serious because their mutual effect has to be addressed. In this study, a two-stage optimization method is proposed for the conceptual design of stiffeners in a ship's prow. In the first stage, a topology optimization method is used to determine a potential stiffener distribution based on the optimal results, whereupon stiffeners are constructed according to stiffener generative theory and the material distribution. In the second stage, size optimization is conducted to optimize the plate and stiffener sections simultaneously based on a parametric model. A final analysis model of the ship-prow structure is presented to assess the validity of this method. The analysis results show that the two-stage optimization method is effective for stiffener conceptual design, which provides a reference for designing actual stiffeners for ship hulls.

• International Journal of High-Rise Buildings
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• v.11 no.3
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• pp.157-170
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• 2022

This paper explains about structural planning and structural design of the high-rise building in Toranomon-Azabudai Project (A Block) which is now under construction. The building is about 330 meters high, has 4.2 aspect ratio, and the outline of the building has shallow curve. We adopted seismic response control structure. The building is a steel rigid frame structure with braces, and it has enough stiffness to obtain its primary natural period to be less than about seven seconds, in consideration of wind response, seismic response and inhabitability for the wind shaking. In terms of business continuity plan, the building has a high seismic performance; value of story drift angle shall be 1/150 or less and members of the building remain almost undamaged while or after a large earthquake. Active mass dumper shall be installed at the top of the building to improve inhabitability while strong wind is blowing.

• Korean Journal of Plant Taxonomy
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• v.43 no.1
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• pp.30-33
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• 2013

Hydrangea luteovenosa is a critically endangered plant species of Jeju Island in Korea, though it is widely distributed in western Japan. We isolated and characterized five microsatellite loci in this species. The number of alleles ranged from 3 to 27, observed heterozygosity from 0.27 to 0.86, and expected heterozygosity from 0.34 to 0.91. The markers described here will be useful for investigating the genetic diversity, genetic structure, and gene flow of H. luteovenosa, and the genetic findings would contribute to the establishment of effective conservation measures for this species in Korea.

• Journal of Korean Dental Science
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• v.6 no.1
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• pp.13-21
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• 2013

Purpose: To report the successful results of using chin bone graft and autogenous tooth bone graft material (AutoBT) in alveolar cleft patients. Materials and Methods: Five patients with alveolar cleft defects underwent alveolar bone grafting. Three patients were treated using chin bone graft, and the other two patients underwent AutoBT graft. After implant site development using chin bone graft in the fi rst three cases, endosseous implant restorations were placed. In case #4 and 5, AutoBT graft material was placed to guide the normal eruption of partially impacted maxillary right canine and to the upper docking site after distraction osteogenesis. Result: Successful implant restorations with closure of the oronasal fistula were achieved in alveolar cleft defect reconstruction using either chin bone graft (Case #1, 2, 3) or AutoBT graft material (Case #4, 5). Case #4 showed enlarged follicle of the right maxillary canine, indicating a normal eruption guide pattern. Conclusion: Both chin bone graft and AutoBT graft showed favorable outcomes in reconstructing alveolar cleft defects. Autogenous tooth bone graft opens up the possibility of avoiding harvesting autogenous bone graft with complications and morbidities.