• Journal of Korean Neurosurgical Society
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• 제42권4호
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• pp.331-336
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• 2007

Objective : The aim of this study was to analyze the treatment results and prognostic factors in patients with massive cerebral infarction who underwent decompressive craniectomy. Methods : From January 2000 to December 2005, we performed decompressive craniectomy in 24 patients with massive cerebral infarction. We retrospectively reviewed the medical records, radiological findings, initial clinical assessment using the Glasgow Coma Scale, serial computerized tomography (CT) with measurement of midline and septum pellucidum shift, and cerebral infarction territories. Patients were evaluated based on the following factors : the pre- and post-operative midline shifting on CT scan, infarction area or its dominancy, consciousness level, pupillary light reflex and Glasgow Outcome Scale. Results : All 24 patients (11 men, 13 women; mean age, 63 years; right middle cerebral artery (MCA) territory, 17 patients; left MCA territory, 7 patients) were treated with large decompressive craniectomy and duroplasty. The average time interval between the onset of symptoms and surgical decompression was 2.5 days. The mean Glasgow Coma Scale was 12.4 on admission and 8.3 preoperatively. Of the 24 surgically treated patients, the good outcome group (Group 2 : GOS 4-5) comprised 9 cases and the poor outcome group (Group1 : GOS 1-3) comprised 15 cases. Conclusion : We consider decompressive craniectomy for large hemispheric infarction as a life-saving procedure. Good preoperative GCS, late clinical deterioration, small size of the infarction area, absence of anisocoria, and preoperative midline shift less than 11mm were considered to be positive predictors of good outcome. Careful patient selection based on the above-mentioned factors and early operation may improve the functional outcome of surgical management for large hemispheric infarction.

• Journal of Korean Neurosurgical Society
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• 제30권3호
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• pp.325-333
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• 2001

Objective : To clarify the benefits and therapeutic effects of intra-arterial papaverine infusion on the symptomatic cerebral vasospasm, we analyzed the results of treatment in 32 patients retrospectively. Methods : A total of 510 patients underwent surgical clipping or endovascular intra-aneurysmal treatment for ruptured intracranial aneurysm between May, 1996 and June, 1999. The delayed ischemic deficit(DID) was developed in 90 of 510 patients. Of these 90 patients, 32 developed symptomatic vasospasm inspite of using modest "3H therapy". The brain CT scan was taken before the intra-arterial infusion of papaverine. The 32 patients underwent 42 intra-arterial papaverine infusion. The symptomatic vasospasm was divided into three groups : deterioration of mental status(Group 1), appearance of a focal neurologic deficit(Group 2), or both(Group 3). We measured Glasgow Coma Scale(GCS), arterial diameters, and cerebral circulation time(CCT) at the time of pre- and postangioplasty. Results : The number of patients in group 1, 2 and 3 were 26, 7, 9 respectively. Eighteen cases showed improvement of GCS more than 2 scores, 16 more than 1, and 8 showed no change of GCS. Average cerebral circulation time(CCT) was decreased ranging from 0.0%-67.5%, and arterial diameters were increased in 21 cases ranging from 1 to 4 folds. Conclusion : Intra-arterial papaverine infusion seemed to have therapeutic effects on symptomatic vasospasm by improving the neurological signs and increasing the arterial diameter. We suggest that intra-arterial papaverine infusion would be an useful adjunctive therapeutic modality in symptomatic vasospasm.

• 대한방사선기술학회지:방사선기술과학
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• 제10권1호
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• pp.43-47
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• 1987

Authors have tested on the characteristics, image qualities and clinical applications of Konica Hi-ortho X-ray film MGH. The results are as followed; 1. The speeds of KM/MG, MGH were as about 2.7 times, and those of KR/MG, MGH were as about 4.5 times as compared with LT-II/A and the tube voltage influenced upon KM/MG, MGH over 80 kVp, upon KR/MG, MGH over 90kVp. 2. Good image definition by the detection of Burger Phanton KM/MGH, KM/MG, and LT-II/A, and good I.Q. values by the detection of Hawlet Chart LT-II/A, KM/MGH, and KM/MG in that order. Therefore, MGH film could reduce the patient dose steeply, and furthermore, provide high image quality by the high contrast and then, it will be very useful to abdominal angiography and cerebral angiography.

• 대한방사선기술학회지:방사선기술과학
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• 제1권1호
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• pp.44-54
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• 1978

This study was carried out with statistical materials during the last two years of period from Jan. 1975 to Dec. 1976 which presented at radiologic department of 5 hospitals in Seoul City. The primary purpose of this study was to obtained more detailed informations related to the activities of radiologic technologists in diagnostic X-Ray examinations part and to provide some basic materials for managements in activities of then and manpower managements of their organization and practice. From the results of this study, the following conclusions were obtained [1] During two year from the January of 1975 to the December of 1976, total number of case in X-ray examinations were 464,830 case and 22,029 case in 1975 and 24,461 in 1976. And ratio of icreased in X-Ray examinations by year was 11.09 per cent. [2] Regarding the examined portion of X-Ray examination, a great propotion was chest examination as 56.88 per cent. [3] An average, the required time per case in X-Ray exam. was 9.28 minutes and make used of 1.94 sheets of X-Ray film per case in radiography. [4] An average, ratio of increased in X-Ray film by year was 12.71 per cent and ratio of failed film in it was 2.23 per cent. [5] The frequency rate of film size showed the highest distribution of $8"{\times}10"$(28.17%) and the highest distribution of X-Ray film by month was July(8.93%). [6] An average, the amount of activities per a diagnostic X-Ray equipment was 34.92 case and make used of 67.81 sheets of X-Ray film in a day. [7] The mean number of case in X-Ray examinations by radiologic technologists was 29.29 cases and make used of 56.87 sheets of X-Ray film in a day. Also, the average number of case was reading by radiologists was 32.42 case and 62.97 sheets of X-Ray film in a day.

• 대한한의학회지
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• 제32권3호
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• pp.18-24
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• 2011

Objective: Leejung-tang (Rechu-to in Japanese) is a traditional Korean herbal formula used for treatment of gastrointestinal disorders such as vomiting, stomach pain, chronic gastritis and gastrointestinal ulceration. The present study was carried out to investigate the potential acute toxicity of Leejung-tang water extract (LJT) by a single oral dose in Crl:CD (SD) rats in compliance with current guidelines. Methods: In the preliminary study, there were no adverse effects such as death, clinical signs, and body weight changes at dose levels of 500, 1000, and 2000 mg/kg/day body weight. Based on the results, a dose of 2000 mg/kg was selected as the toxicological limited dose. LJT was administered once by gavage to male and female rats at dose levels of 0 and 2000 mg/kg bodyweight. During the study period, mortalities, clinical findings, and body weight changes were observed for 14 days following the administration. On day 14 after the treatment, the animals were sacrificed by carbon dioxide overdose and complete gross postmortem examinations were performed. Results: In present study, no treatment-related deaths were observed. There were no adverse effects on clinical signs and body weight changes. In addition, there were no observed gross findings in all groups except for a kidney cyst in the 2000 mg/kg/day female group. Conclusion: The results indicated that LJT did not induce toxic effects at a dose level up to 2000 mg/kg in rats and its median lethal dose ($LD_{50}$) was considered to be over 2000 mg/kg/day body weight for both genders.

• 대한방사선기술학회지:방사선기술과학
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• 제5권1호
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• pp.35-43
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• 1982

The authors surveyed the cassettes in 10 general hospitals and compared in experimentation on performances of 6 kinds of cassettes manufactured with several materials in order to discover the present condition and performance of the cassettes being used at present. And the authors got the following results. 1. In distribution of the cassettes in use, Okamoto's(Japan), Picker's and Titan's(U.S.A.) were more than others classified by the manufacture. The rate of using high speed was 72.0%, par speed 28.0% classified by types of intensifying screens in the cassettes and the rate of the year in use for $4{\sim}5$ years was 40.0%, $6{\sim}7$ years 24.0% classified by the years in use. 2. The results of the screen-film contact test were that tile ordinary was 42.7%, the good 36.0%, and the poor 21.3%. 3. The results of the test for light leakage were that fogged area appeared on 1 side or more in 84.0% films. 4. In Aluminum equivalents of front plate, the cassettes with a front plate consisting of carbon fiber were fewest, and the ones of bakelite and aluminum were fewer in order 5. In compared results of the exposure dosage for same density of the films, the exposure of the cassettes used carbon fiber for the material on the front plate was smallest and bakelite, auminum was smaller in order.

• 동의생리병리학회지
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• 제24권3호
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• pp.426-429
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• 2010

This study was conducted to investigate the acute toxicity and safety of Pyungwi-san (Pingwei-san) in Sprague-Dawley rat though the current regulatory guideline. The preliminary study showed that the single oral administration of Pyungwi-san (Pingwei-san) did not induce any toxic effect at a dose level of 2000 mg/kg. Based on the results, 2000 mg/kg was selected as the limited dose. In this study, 10 rats of each sex were randomly assigned to two groups of 5 rats each and were administrated singly by gavage at dose levels of 0 and 2000 mg/kg. After single administration, Mortalities, clinical signs, body weight changes, gross findings were observed for the 15-day period. Throughout the study period, no treatment-related deaths were observed. There were no adverse effects on clinical signs, body weight, and gross findings at all treatment groups. These results showed that the single oral adminstration of Pyungwi-san (Pingwei-san) did not cause any toxic effect at the dose levels of 2000 mg/kg in rats. In conclusion, the $LD_{50}$ of Pyungwi-san (Pingwei-san) was considered to be over 2000 mg/kg body for both sexes.

• 대한환경공학회지
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• 제35권8호
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• pp.571-578
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• 2013

본 연구에서는 음폐수를 이용 낮은 유기물 부하율에서 소화조 내부 pH 조절 유무에 따른 소화조 운전의 바이오가스 발생량 및 미생물 군집도 변화에 대한 비교 분석했다. 그 결과, 내부 pH를 조절하지 않은 반응조는 pH, Free ammonia, Volatile fatty acid의 증가에 의한 반응조 안정성이 떨어짐에도 불구하고 내부 pH 조절 반응조와 비슷한 바이오가스 전환율을 보였다. 이는 미생물 군집도 분석 결과에 따르면 외부환경에 대한 내성이 강한 Methanosarcina sp.의 우점에 의해 반응조의 안정성을 유지할 수 있었던 것으로 나타났다.

• 한국지반환경공학회 논문집
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• 제11권5호
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• pp.15-23
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• 2010

한강, 낙동강, 영산강, 금강의 하천 및 호소퇴적물을 대상으로 건식체질법, 습식체질법, 광산란법(PSA) 등의 입도분석법을 비교연구 하였다. 건식체질법의 경우 건조과정에서 발생하는 엉김현상에 의해 오차가 크게 발생하며 이러한 현상은 호소시료의 경우 두드러지게 나타났다. 습식체질법은 건식체질법에 비해 복잡하고 노동력이 보다 많이 필요하지만 정확한 분석이 가능하며 PSA의 경우에도 습식체질과 유사한 경향을 나타내었다. 엉김현상을 방지하기 위한 동결건조 및 과산화수소수에 의한 유기물의 산화/동결건조의 경우 엉김현상을 일부 개선할 수 있었으나 여전히 습식체질에 비하여 미세입자의 분율이 적게 나타났다. 입도별 중금속의 용출량 및 함유량이 조사되었으며 예상된 바와 같이 호소 및 하천시료 모두 미세입자에서 높은 농도의 중금속이 용출되었다. 퇴적물의 관리에 있어서 정확한 입도분석법의 사용과 미세입자에 대한 관리가 보다 중요하다.

• 척추신경추나의학회지
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• 제8권2호
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• pp.151-157
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• 2013

Objects : This study is a report on treatment effect of the case that treated by using of Shinbaro pharmacopunture and acupuncture to plantar fasciitis patients. Methods : The four patients diagnosed with Plantar fasciitis were treated by using of Shinbaro pharmacopunture and acupuncture, Algometer Pressure and Numeric rating scale(NRS) were used as the evaluation tool of treatment effect. Results : Shinbaro pharmacopunture and acupuncture showed improvement of symptoms for all patient groups and brought about significant change on numerical value of Algometer Pressure and Numeric rating scale(NRS). Conclusions : The result shows that Shinbaro pharmacopunture and acupuncture can be effective treatment to Plantar fasciitis. Merely later, further study is needed.