• Title/Summary/Keyword: service standards

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Simultaneous Determination of Five Porphyrins in Human Urine and Plasma Using High Performance Liquid Chromatography-Tandem Mass Spectrometry

  • Hur, Yeoun;Tae, Sookil;Koh, Yun-Joo;Hong, Sung-Hyun;Yoon, Young Ho;Jang, Haejong;Kim, Sooji;Kim, Kyeong Ho;Kang, Seung Woo;Lee, Youngshin;Han, Sang Beom
    • Mass Spectrometry Letters
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    • v.5 no.2
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    • pp.42-48
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    • 2014
  • A specific and sensitive liquid chromatography-electrospray ionization tandem mass spectrometry method (LC-ESI-MS/MS) was developed and validated for the simultaneous quantification of porphyrins (coproporphyrin, pentacarboxylporphyrin, hexacarboxylporphyrin, heptacarboxylporphyrin, and uroporphyrin) in human plasma and urine. Acidified plasma samples and urine samples were prepared by using liquid-liquid extraction using ethyl acetate and protein precipitation with acetonitrile, respectively. The separation was achieved onto a Synergi Fusion RP column ($150mm{\times}2.0mm$, $4{\mu}m$) with a gradient elution of mobile phase A (0.1% formic acid in 2 mmol/L ammonium acetate, v/v) and mobile phase B (20% methanol in acetonitrile, v/v) at a flow rate of $450{\mu}L$/min. Porphyrins and the internal standard (IS), coproporphyrin I-$^{15}N_4$, were detected by a tandem mass spectrometer equipped with an electrospray ion source operating in positive ion mode. Multiple reaction monitoring (MRM) transitions of the protonated precursor ions and the related product ions were optimized to increase selectivity and sensitivity. The proposed method was validated by assessing selectivity, linearity, limit of quantification (LOQ), precision, accuracy, recovery, and stability. The calibration curves were obtained in the range of 0.1-100 nmol/L and the LOQs were estimated as 0.1 nmol/L for all porphyrins. Results obtained from the validation study of porphyrins showed good accuracy, precision, recovery, and stability. Finally, the proposed method was successfully applied to clinical studies on the autism spectrum disorder (ASD) diagnosis of 203 Korean children.

Reclassification of an legal communicable disease (가축전염병 분류의 새로운 개편)

  • Park, Jae-Myoung;Lee, Jong-Jin;Kwak, Hak-Koo
    • Korean Journal of Veterinary Service
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    • v.30 no.3
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    • pp.473-480
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    • 2007
  • The legal communicable diseases are classified two group, 62 diseases in the existing domestic animal Infectious disease prevention Act. There is problem that standards of administrative measure are unjustly suspected when infectious disease outbreaks between two groups, Therefore, A reclassification of many diseases should be diversified, the standards of administrative measure at the infectious diseases outbreak should be desired. Also, It suggest that central government should mandate local government to be able to assign legally designated disease about specific endemic diseases.

A Study on the Corresponding Strategies in Technology Standards of IMT-2000 in Korea (IMT-2000서비스 도입에 따른 기술표준별 대응전략에 관한 연구)

  • 송영화;장수덕
    • Proceedings of the Korea Association of Information Systems Conference
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    • 2001.12a
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    • pp.166-178
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    • 2001
  • Lately the National Technology Standard of IMT-2000 service in Korea was decided for both technology standards (cdma-2000, W-CDMA), and consequently the comprehensive countermeasures against the Technology Standards are all the more emphasized. Especially to private enterprises which were selected as service carriers for IMT-2000 service in Korea, making corresponding strategies in relation to both technology standards must be settled without delay. The Government also should serve the development of the I&T Industry through the various processes of adopting the policies and working out strategies In relation to Technology Standards of IMT-2000. Therefore in this paper, 1 would like to survey the features of both Technology Standards(cdma-2000, W-CDMA) and to propose the hereafter corresponding strategies in relation to IMT-2000 services.

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The Communication Protocol Model for Semiconductor Equipment with Internet of Things (사물인터넷을 이용한 반도체 장비 통신 프로토콜 모델)

  • Kim, Doo Yong;Kim, Kiwan
    • Journal of the Semiconductor & Display Technology
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    • v.18 no.4
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    • pp.40-45
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    • 2019
  • The smart factory has developed with the help of several technologies such as automation, artificial intelligence, big data, smart sensors and communication protocols. The Internet of things(IOT) among communication protocols has become the key factor for the seamless integration of various manufacturing equipment. Therefore, it is important that the IOT cooperate with the standards of communication protocols proposed by the SEMI in the semiconductor industry. In this paper, we suggest a novel reference model of the communication protocols for semiconductor equipment by introducing an IOT service layer. With the IOT service layer, we can use the functions and the additional services provided by the IOT standards that give the inter-operability between factory machines and host computers. We implement the standard of the communication protocols for semiconductor equipment with the IOT service layer by using ns3 simulator. It concludes that it is necessary to provide the platform for the IOT service layer to deploy efficiently the proposed reference model of the communication protocols.

A Development of DC-DC Converter for the Reading Lamp of TGV-Korea (고속 철도(TGV-Korea) 조명용 DC-DC 컨버터의 개발)

  • 김성일;김희준;김희일
    • Proceedings of the KIPE Conference
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    • 1999.07a
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    • pp.635-638
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    • 1999
  • Manufacturing TGV-Korea, international standards and TGV-standards should be strictly applied in order to insure the normal operation and the safety of passengers in a train service. This paper presents a development of 800W DC-DC converter for the reading lamp of TGV-korea. The converter is designed for satisfying the regulations of international standards and TGV-standards regarding the burning-in test, the vibration test, the electro-magnetic emissions test, etc. As an experimental result, the maximum efficiency is obtained as 92.3[%] at normal input voltage and output power.

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Developing a Management Improvement Supporting Solution in Consideration of Service Quality (서비스품질을 고려한 경영혁신 지원 솔루션의 개발)

  • Park, C.S.;Ahn, S.E.;Shin, W.S.;Ryu, J.S.;Park, J.W.;Woo, M.K.
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.31 no.2
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    • pp.28-35
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    • 2008
  • Most organizations have recently put more emphasis on the improvement in service quality. This phenomenon could come from the recognition that service quality plays an essential role in enhancing organization's business performance. Hence this paper presents a framework for improving such service quality. The presented framework involves the methodology for (i) developing service quality indices, (ii) measuring and evaluating service quality, (iii) analyzing the level of service quality, (iv) constructing the quality improvement road map, (v) determining the quality improvement action plan. This methodology is intended to create self-sustaining improvement in service quality from the entire organization's perspective. An illustration is also given.

The design and implementation of Service architecture for USN application service (USN 응용 서비스를 위한 서비스 아키텍처의 설계 및 구현)

  • Shin, Geuk-Jae;Kim, Yong-Woon;Yoo, Sang-Keun;Kim, Hyung-Jun;Jung, Hoe-Kyung
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.14 no.4
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    • pp.1015-1022
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    • 2010
  • USN(Ubiquitous Sensor Network) environment that provides the service measured from sensors in real-time the information is delivered to application service. However, domestic service, application service provider environment between providers and users, most of the research are on the service platform architecture, and process the information detected by sensors between the providers of standard services platform architecture, which is a very weak level. In this paper, we proposed new service architecture though analysis of the OGC SWE(Sensor Web Enablement) with standards and research analysis of domestic standards. And we designed and implemented to each component of provider side.

A Study on the Improvement of Standards of Traffic Information Service and Provide Services Based on the Detailed Traffic Information (교통정보서비스 표출기준 개선 및 상세교통정보 기반 서비스 제공방안 연구)

  • Bae, Kwangsoo;Lee, Seungcheol
    • Journal of Information Technology Services
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    • v.17 no.4
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    • pp.85-100
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    • 2018
  • In this study, we formulated rational criteria to efficiently provide traffic information services via a crafted approach. By utilizing this, we presented a detailed traffic information service providing method that can overcome the limitations of existing link unit information provision system. Three methodologies such as user survey, data mining, and KHCM (Korea Highway Capacity Manual) utilization method were applied to formulate a rational expression standard for traffic information service. Each method was designed to establish a quantitative criterion for various traffic conditions and to enable user-oriented traffic information service in consideration of the traffic principal/compatibility. Considering the results of each methodological analysis in a comprehensive manner, the basic expression standards for traffic information service was formulated. Then we presented improvements such as traffic condition step by road, speed range of traffic condition, expression term of traffic condition and so on. In order to complement the problems of the information provision system of the existing link unit based on the derived improvement criterion, we presented the detailed traffic information service provision method by using the traffic speed data of the second order. And we applied this to the two links of Daegu city. The method presented in this research can improve the quality of traffic information service. Not only it can be used for various fields such as optimal route search, traffic safety service and so on.

Investigation of EU, UK and USA's Laws and Standards related to Safety Criteria for Commercial Kitchen Machines (유럽연합, 영국 및 미국의 주방 기기 안전 기준 관련 법령 및 규격 조사)

  • Kee, Do-Hyung;Hwang, Sang-Don;Song, Young-Woong;Park, Hyun-Geun
    • Journal of the Korea Safety Management & Science
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    • v.19 no.2
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    • pp.51-61
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    • 2017
  • The purpose of this study is to investigate EU, UK and USA's laws and standards related to safety criteria for commercial kitchen machines. The study was based on literature survey and web surfing. The results revealed that EU has relevant directives by kitchen machines and harmonized standards according to the directives. The directives and harmonized standards are translated into the laws and standards of EU member countries, respectively. The kitchen facility relevant legal systems of UK and USA do not prescribe the safety devices or measures, but only the basic health and safety requirements. The requirements were forcefully implemented through the certificate systems such as CE(Confommite European), UL(Underwriters Laboratories), etc. Only products with CE, UL or NRTL(ationally Recognized Testing Laboratory) certificate marking can be placed on the market of EU and USA, or put into service. For achieving the certificates, all requirements regulated in the relevant standards should be met. The standards of UK and USA were presented by kitchen machines or by standards themselves, respectively. Safety devices required by the standards were also summarized by kitchen machines and their risk factors.

A study on improving the performance of special ambulances (특수구급차 성능 개선을 위한 조사 연구)

  • Yoon, Byoung-Gil;Yang, Hyun-Mo;Kim, Gyoung-Yong
    • The Korean Journal of Emergency Medical Services
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    • v.26 no.1
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    • pp.87-99
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    • 2022
  • Purpose: This study aimed to provide basic data for the improvement of the standards related to the performance improvement of the firefighting equipment standards for special ambulances. Methods: Among the domestic firefighting equipment standards, the special ambulance standard was compared with the NFPA 1917 standard for the United States automobile ambulance 2019 and European Union European standard EN 1789 medical vehicle and its equipment, a road ambulance. Results: Anti-skid performance based on indoor noise standards, performance standards for interior lights, seat belt warning device, child car seat fixing device, safety handle, auxiliary footrest, and flooring materials should be supplemented. Conclusion: It is necessary to strengthen the production and performance standards for improvement to a level corresponding to the national standards, such as the United States and European Union.