• 대한한의학방제학회지
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• 제30권4호
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• pp.241-248
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• 2022

Objective : The purpose of this trial is to observe the preliminary effects of Salvia plebeia (SP) extract on quality of life in patients with solid cancer. Methods : This is a prospective, open-label, single-arm, and single-dose clinical trial. Twenty participants who have been diagnosed with solid cancer between the ages of 20 and 65 will be included. All participants will be administered SP granules for 12 weeks. Data will be collected at 4, 8, and 12 weeks after enrollment. The primary outcome is quality of life, using the Korean version of the Functional Assessment Cancer Therapy-General questionnaire. Secondary outcomes include tumor markers in blood tests for each cancer type, soluble programmed death-ligand 1, the percentage of natural killer cells among lymphocytes, ratio of T-helper and T-suppressor cells, ratio of total T, T-helper, T-suppressor, and B cells in lymphocytes, level of C-reactive protein, and tumor size via radiology examination. Safety will be assessed by clinical laboratory tests and monitoring of adverse events. Discussion : This study aims to observe the effects of an oral administration of SP preparations in patients with solid cancer on changes in quality of life and an improvement in immune function. It is expected to provide objective evidence of the effect and safety of SP for patients with solid cancer. Trial registration: KCT0007315 (Clinical Research Information Service)

• Journal of Preventive Medicine and Public Health
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• 제55권6호
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• pp.529-538
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• 2022

Objectives: This study aimed to identify the current patterns of cancer incidence and estimate the projected cancer incidence and mortality between 2020 and 2035 in Korea. Methods: Data on cancer incidence cases were extracted from the Korean Statistical Information Service from 2000 to 2017, and data on cancer-related deaths were extracted from the National Cancer Center from 2000 to 2018. Cancer cases and deaths were classified according to the International Classification of Diseases, 10th edition. For the current patterns of cancer incidence, age-standardized incidence rates (ASIRs) and age-standardized mortality rates were investigated using the 2000 mid-year estimated population aged over 20 years and older. A joinpoint regression model was used to determine the 2020 to 2035 trends in cancer. Results: Overall, cancer cases were predicted to increase from 265 299 in 2020 to 474 085 in 2035 (growth rate: 1.8%). The greatest increase in the ASIR was projected for prostate cancer among male (7.84 vs. 189.53 per 100 000 people) and breast cancer among female (34.17 vs. 238.45 per 100 000 people) from 2000 to 2035. Overall cancer deaths were projected to increase from 81 717 in 2020 to 95 845 in 2035 (average annual growth rate: 1.2%). Although most cancer mortality rates were projected to decrease, those of breast, pancreatic, and ovarian cancer among female were projected to increase until 2035. Conclusions: These up-to-date projections of cancer incidence and mortality in the Korean population may be a significant resource for implementing cancer-related regulations or developing cancer treatments.

• 한국문헌정보학회지
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• 제56권4호
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• pp.285-307
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• 2022

본 연구에서는 도서관의 개인의 가능성 발견과 관련하여 현재 「제3차 도서관종합발전계획」에 발표된 정책을 살펴보고, 해당 정책을 기반으로 중앙행정기관과 시·도 도서관에서 추진한 과제 현황을 분석하였다. 이를 기반으로 향후 개인의 가능성을 발견하는 도서관의 역할을 수행하기 위한 방향을 제시하였다. 연구 결과, 코로나19로 인문·문화 프로그램 등 비대면 서비스 진행 도모, 도서관 휴관 따른 대면행사 축소로 실적이 저조하여 코로나19 대응 비상관리 및 비대면 프로그램 운영 지원체계 구축과 소외 지역 및 소외 계층의 독서문화 사업의 확대 운영을 위한 예산 증액이 필요할 것으로 파악되었다. 또한 장기적 양질의 비대면 프로그램 발굴과 비대면 프로그램 운영 위한 인프라 지원, 가이드라인 개발이 필요한 실정임을 파악하였다. 둘째, 소통·토론형 사회적 독서 프로그램은 온라인 강좌 전환 운영이 빠르게 전환될 필요성을 감지했다. 셋째, 이용자 정보접근 편의확대 개선과 국내·외 협의회 간 세미나 운영, 자료 원스톱 공유 시스템 활성화 및 자료의 디지털화 추진, 포스트코로나 시대 대비 하는 도서관 인프라 확충, 홍보 활성화 등 대외협력 강화 방안 마련이 필요할 것으로 파악되었다.

• 재활치료과학
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• 제11권3호
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• pp.23-36
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• 2022

목적 : 본 연구는 전환프로그램 연구동향과 장애청소년을 대상으로 국내외 전환프로그램의 중재 및 효과를 체계적으로 분석함으로써 학교 및 지역사회 관련 기관들과 협력하여 성인생활의 모든 측면을 포함할 수 있는 중재 전략에 대한 기초자료를 제공하는 것을 목적으로 한다. 연구방법 : 학술연구정보서비스(Research Information Sharing Service: RISS), Pubmed, Web of Science(WoS) 데이터베이스를 사용하여 2006년부터 2021년까지의 게재된 논문을 검색하였다. 주요 검색어는 'Disability' AND ('Adolescents' OR 'Young adult') AND ('Transition education' OR 'Transition program')를 사용하였다. 최종적으로 7편의 국내외 논문을 본 연구의 분석 대상으로 선정하여 전문을 검토하였다. 또한, WoS(Web of Science) 플랫폼과 VOSviewer(version 1.6.16, CWTS, Netherlands, 2020) 프로그램을 이용하여 키워드와 국가 관계를 분석하고 시각화하였다. 결과 : 7개의 논문에서 참여한 대상자를 유형별로 분석한 결과, 대상자는 ASD, ADHD, ID, DD, physical disability 총 5가지로 분류되었다. 중재에 사용된 영역은 크게 직업(학업), 자기관리(시간), 상호작용(대인관계, 의사소통) 3가지 범주로 혼합되어 실시되었다. 중재 결과 7편 중 1편을 제외하고는 사회성 및 적응, 삶의 질, 일상생활활동 세 가지 분류 중 적어도 하나 이상의 부분에서 유의미한 향상을 보였다. 결론 : 본 연구는 전환프로그램의 연구동향을 파악하면서 프로그램의 적용과 그 효과를 정리하여 다양한 전문가와의 교류하는 방향성을 제시하는 동시에 단편적인 측면이 아닌 성인생활의 모든 측면을 확대하는 기초자료로 활용될 수 있을 것이다.

• Journal of Korean Neurosurgical Society
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• 제65권5호
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• pp.741-750
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• 2022

Objective : In March 2020, World Health Organization declared a global pandemic caused by a novel coronavirus (SARS-CoV-2). The disease caused by this virus is called COVID-19. Due to its high contagiousness, many changes have occurred in overall areas of our daily life including hospital use by patients. The aim of this study was to investigate the impact of COVID-19 on volume of spine surgery in South Korea using the National Health Insurance database and compare it with the volume of a homologous period before the pandemic. Methods : Data of related to spine surgery from January 2019 to April 2021 were obtained from the National Health Insurance and Health Insurance Review and Assessment Service database. Primary outcomes were total number of patients, rate of patients per 100000 population, and total number of procedures. The number of patients by hospital size was also analyzed. Results : COVID-19 outbreaks occurred in South Korea in March, August, and December of 2020. Compared to the previous year, the total number of patients who underwent spinal surgery showed a decrease for 2-3 months after the first and second outbreaks. However, it showed an increasing trend after the third outbreak. The same pattern was observed in terms of the ratio of the number of patients per 100000 population. Between 2019 and 2021, the mean number of spine surgeries per month tended to increase. Mean annual medical expenses increased over the years (p=0.001). When the number of spine surgeries was analyzed by hospital size, proportion of tertiary general hospital in 2021 increased compared to those in 2019 and 2020 (vs. 2019, p=0.012; vs. 2020, p=0.016). The proportion of general hospital was significantly decreased in 2020 compared to that in 2019 (p=0.037). Conclusion : After the COVID-19 outbreak, patients tended to postpone spinal surgery temporarily. The number of spinal surgeries decreased for 2-3 months after the first and second outbreaks. However, as the ability to respond to the COVID-19 pandemic at the hospital and society-wide level gradually increased, the number of spine surgeries did not decrease after the third outbreak in December 2020. In addition, the annual number of spine surgeries continued to increase. However, it should be noted that patients tend to be increasingly concentrated in tertiary hospitals for spinal surgery.

• 대한예방한의학회지
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• 제26권2호
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• pp.55-67
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• 2022

Objectives : This study is aimed to survey Korean Medicine Doctors's perceptions in Korean Medicine Clinical Practice Guideline and Standard Korean Medicine Clinical Pathways for its spread(to increase utilization in clinical sites). Methods : The research population was set at 14,831 Korean medical institutions registered with the Health Insurance Review and Assessment Service for sampling representative of Korean Medicine Doctors, and the final 2,007 subjects were selected in consideration of the research period and budget. This survey was conducted based on a telephone survey, and in some cases, a fax or e-mail survey was also conducted together. Six questions were asked about the perception of 'Korean Medicine Clinical Practice Guideline and Standard Korean Medicine Clinical Pathways', and three questions about the characteristics of the respondent. Results : The rate of recognizing Korean Medicine Clinical Practice Guideline was 36.1%. Those who worked at Korean medicine hospitals, were under 39 years of age, and had less than 11-20 years of experience as an Korean medical doctor were more likely to be aware of it. Regarding the experience of using Korean Medicine Clinical Practice Guideline, the rate of 'not used in the past and not used now' was very high at 82.9%, but the intention to use it in the future was high at 60.7%. About the Korean Medicine Clinical Pathways, 79.9% of respondents answered that they did not know. 80.6% of respondents recognized the need for the development of clinical manuals such as Korean Medicine Clinical Practice Guideline and Standard Korean Medicine Clinical Pathways. Conclusion : Their low awareness of Korean Medicine Clinical Practice Guideline seems to affect its low utilization. Therefore, active education and public relations are required in the future.

• 대한한의학회지
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• 제43권1호
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• pp.136-153
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• 2022

Objectives: The aim of this study was to find out whether east asian herbal medicine (EAHM) treatment alone is effective in improving pregnancy-related indicators compared to conventional medicine in women with Diminished Ovarian Reserve (DOR). Methods: We searched eligible studies from PubMed, Cochrane Library, EMBASE, Chinese National Knowledge Infrastructure Database, CiNii, Korean Medical Database, Korean Studies Information Service System, Oriental Medicine Advanced Searching Integrated System, ScienceOn. GRADE pro was used to evaluate the current evidence of the study. Result: A total of 5 studies, 325 women with DOR were included. EAHM showed a significant effect on improvement of pregnancy rate (n=270, RR 2.13 [95% CI 1.44 to 3.15], Z=3.78, p=0.0002, I2=0%) and Anti-Mullerian Hormone (AMH) level (n=211, SMD 0.82 [95% CI 0.40 to 1.25], Z=3.80, p=0.0001) compared to conventional medicine. In ovulation rate (n=156, RR 0.86 [95% CI 0.70 to 1.06], Z=1.43, p=0.15, I2=0%), Antral Follicle Count (n=245, SMD 0.27 [95% CI -0.25 to 0.79], Z=1.01, p=0.31), and follicle stimulating hormone (n=245, SMD 0.29 [95% CI -0.13 to 0.70], Z=1.36, p=0.17) level, EAHM showed similar effects to conventional medicine. In this study, the most frequently used herbal medicines were Cuscutae Semen, Dipsaci Radix, and Angelicae Gigantis Radix. Conclusion: This meta-analysis showed that EAHM could improve pregnancy rates and AMH levels in women with DOR. However, more well-designed RCTs will have to be performed further in the future.

• 한국융합학회논문지
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• 제13권2호
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• pp.185-200
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• 2022

박물관 문화 콘텐츠의 혁신적 개발은 박물관이 소장품을 이용하여 문화의 전파 기능을 강화하는 중요한 방법이다. 사람들의 소비 수준이 늘어나고 업그레이드화됨에 따라 전통적인 문화 콘텐츠 디자인과 판매 방식은 날로 늘어나는 소비자들의 욕구를 충족시키지 못하고 있다. 본고는 박물관 문화 콘텐츠의 맞춤형 체험 플랫폼 구축을 제안하여 박물관 문화 콘텐츠의 개발을 촉진하고 박물관 문화의 전승과 보호를 도모하려 한다. 본고의 연구방법은 선행연구를 정리하고 분석하여 기존의 플랫폼 모델과 특징을 분석하고 설문지 159부를 배포하여 문화 콘텐츠 소비자들의 욕구를 조사하였다. 마지막으로 사용자 요구에 따른 맞춤형 체험과 현존하는 인터넷 소매 플랫폼과 결합하여 이론적 틀을 만들었으며 선양 고궁박물관을 중심으로 실험을 설계하고 가용성 테스트를 진행했다. 연구결과를 보면 문화 콘텐츠 플랫폼에 대한 사용자의 수요도가 비교적 높았다. 맞품형 플랫폼을 이용한 디자인은 박물관 문화 콘텐츠의 확산과 확대를 촉진하며 사용자의 경험을 최적화하여 박물관의 콘텐츠 개발과 디자인, 소매 등에 새로운 생각을 부여한다. 따라서 본고는 박물관의 문화 콘텐츠 개발은 맞춤형 플랫폼에 따라 소비자들의 특성에 맞춰 소비자들의 서비스 경험을 더욱 향상할 것으로 기대한다.

• International Journal of Computer Science & Network Security
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• 제22권10호
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• pp.183-190
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• 2022

The article analyzes the features of the formation of a person's value attitude to the worldview by means of information technologies. The present considers it necessary to form a person's value attitude to the perception of the world by means of information technologies. The explosive development of information and telecommunications technologies has become a determining factor in the development of modern society, which is called the information or Global Information Society. It is not yet fully formed, and we are all participants in the development of the Global Information Society. The article considers the basics of a harmonious worldview of a person, which is the basis for the formation of outlook ideas, views, knowledge, beliefs about the surrounding world, which determine the place and role and motivate actions in relation to the surrounding reality through the prism of value orientations. Worldview is considered as an integrity of relatively stable schemes, behaviors, feelings, thinking, vision of the surrounding world, inherent in an individual child, ethno-cultural and socio-cultural groups. The concept of "worldview" as a component of the multi-level structure of the individual's outlook is defined. The features that characterize a person's perception of the world are revealed. The main educational value of information technologies in the formation of a person's value attitude to the perception of the world is highlighted, which consists in the fact that they allow you to create an immeasurable brighter multi-sensory interactive learning environment with almost unlimited potential opportunities that fall at the disposal of both the teacher and the student. The trend of forming a person's value attitude to the perception of the world is clearly developing in the direction of mixed learning as a process that creates a comfortable information educational environment, communication systems that provide all the necessary educational information. The approach to student development by means of the educational environment and the formation, while in the person of a value attitude to the perception of the world by means of Information Technologies, has many pedagogical advantages, which is considered in the article.

• 한국구조물진단유지관리공학회 논문집
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• 제26권6호
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• pp.230-237
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• 2022

철근 콘크리트 구조물의 사용 수명 확보는 경제적인 측면과 안전성을 고려하였을 때 필수적이다. 현장에 노출된 콘크리트에서 염해는 대표적인 열화 현상으로 잘 알려져 있다. 이를 사전에 예방하기 위한 방안으로 시멘트 대체재인 고로슬래그 (Ground granulated blast-furnace slag; GGBS)를 혼입하여 염해 저항성을 높이는 연구가 다양하게 진행하였고, 현재는 GGBS를 혼입한 콘크리트의 사용이 의무화되고 있다. 현장 콘크리트는 대부분 수분 불포화 상태를 유지하기 때문에 흡수 현상에 대한 연구가 필요하지만, 기존의 연구는 염화물 확산에 초점이 맞춰진 연구가 대부분이다. 콘크리트 내의 염화물 흡수을 측정하기 위해 제시된 방법들은 대부분은 실험실에서 수행이 가능한 고가의 장비를 사용하고 있다. 흡수현상을 간단하고 실용적으로 평가할 수 있는 기술 개발이 필요하다. 본 연구에서 선행 연구로 GGBS 콘크리트의 염해 저항성을 염화물 흡수 시험의 무게 변화와 임피던스 측정을 통해서 평가하였다. 실험 결과를 보면, 염화물 흡수양과 측정된 전기비저항(또는 전기전도도)와 선형적 상관관계를 확인할 수 있었다. 흡수 시험이 완료된 시점에서 측정된 전기전도도는 PC 콘크리트의 경우 250.8 S/m (w/b=0.4)과 303.1 S/m (w/b=0.6)이고, GGBS 콘크리트는 42.6 S/m (w/b=0.4)과 64.4 S/m (w/b=0.6) 로 나타났다. GGBS 콘크리트의 염해저항성이 높은 것으로 판단된다. 본 연구에서는 염화물 흡수 및 임피던스 측정에 영향을 미치는 인자를 고려하였을 때, GGBS 사용에 따른 콘크리트의 공극 구조가 염해 저항성에 주요한 영향을 미치는 것을 확인할 수 있었다. 콘크리트 배합시 사용되는 결합재의 종류에 따라 공극구조가 다르게 나타날 수 있으므로 염해 환경에 노출된 구조물 건설시에는 결합재 사용에 대한 주의가 필요할 것으로 판단된다.