• 제목/요약/키워드: serum values

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國內飼育 원숭이의 血淸 CPK의 總活性値와 isoenzyme에 관한 硏究 (Studies on the Serum total Activities and Isoenzyme Patterns of CPK in non-human Primates Reared in Korea)

  • 윤상보;김덕환;서지민;신남식;현병화;박배근;송희종
    • 한국임상수의학회지
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    • 제18권4호
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    • pp.390-396
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    • 2001
  • CKP isoenzymes have a high level of efficaciousness as diagnostic and prognostic aids in various diseases. There is not any report on the total activity of CPK of non-human primates, let alone CPK isoenzyme patterns, in Korea. In this study, total activities and isoenzyme patterns of CPK were measured to obtain their reference values in domestically reared common marmosets, crab-eating macaques and Japanese macaques. We observed remarkable different values of serum total CPK from the primates used in this experiment. Serum CPK activities of Japanese macaques and crab-eating macaques were 275.8$\pm$158.1 IU/l and 396.7$\pm$697.4 IU/l, respectively, whereas those of common marmosets showed much higher value of 618.8$\pm$1,117.6 IU/l. In all common marmosets and crab-eating macaques, only CPK$_3$ ws observed. In five out of eight Japanese macaques, CPK$_3$ was the sole fraction but two animals showed CPK$_1$ and CPK$_3$ isoenzymes, and the remaining one had CPK$_2$ and CPK$_3$ fractions. There were some discrepancies in the pattern and ratio of isoenzyme fractions in Japanese macaques. In conclusion, values such as CPK and CPK isoenzyme patterns of investigated for the first time form non-human primates reared in Korea, could be reference values for the optimal diagnosis and therapy diseases of the corresponding animal species.

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체외순환후의 혈청효소치 변동에 관한 연구 (Serum Enzyme Values after Extracorporeal Circulation)

  • 이상호;김종환
    • Journal of Chest Surgery
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    • 제14권2호
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    • pp.144-152
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    • 1981
  • The effect of cardiopulmonary bypass procedures on the blood components were studied through the measurements of several serum enzymes, SGOT, SGPT, CPK and LDH with its isozymes in the patients who had surgery for their heart diseases. They wre 85 patients: 40 Males and 45 Females. Their ages ranged widely between one and fifty-six. They were divided into 5 groups: Group I.patent ductus arteriosus without extracorporeal circulation, Group II-atrial septal defect, Group III-ventricular septal defect, Group IV-tetralogy of Fallot, and Group V-valve replacement. Generally serum enzymes revealed the increased values after surgery and the tendency returning toward preoperative levels. With the high total serum LDH levels seen uniformly after operation which persisted long in patients with replaced valves, the changes of LDH-isozymes were further analyzed. The isozymes, especially LDI and LDs increased their activities postoperatively, and the other fractions varied little. And $LD_1$/$LD_2$ ratios also showed similar rises and falls while the elevated values lasted longer in the patients with cardiac valve replacement. The significant values of LDH-isozymes in predicting the hemolysis occuring after extracorporeal circulation and in following the patients whose valves were replaced have been further discussed with the special stress placed on the $LD_1$/$LD_2$ratios.

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진도견(珍島犬)의 혈액화학치(血液化學値) (Serum chemisty values for Jindo dogs)

  • 이정길;최한선;박영준;이채용
    • 대한수의학회지
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    • 제32권1호
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    • pp.153-156
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    • 1992
  • 임상적으로 건강한 진도개 179두의 혈액화학치(血液化學値)와 혈청효소치(血淸酵素値)를 조사하였다. 179두에는 암수가 다 포함되어 있었고 연령은 3개월에서 10세까지 이었다. 혈청효소치(血淸酵素値)는 연령에 따른 변화를 나타내지 않았으나 측정된 화학치(化學値)의 대부분은 연령에 따라 변화하였다. 효소치(酵素値)중에 gamma glutamyltransferase 활성도는 진도개에서는 처음으로 측정된 것이었는데 다른 품종의 개의 정상치 범위내에 들어 있었다. 한편 혈청총단백양(血淸總蛋白量)과 알부민량(量)만 성(性)에 따른 변화를 나타냈다.

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간질감염(肝蛭感染)이 한우혈액(韓牛血液)의 구성성분(構成成分)에 미치는 영향(影響) (Changes in Blood Cellular Components, Serum Chemical Values and Serum Enzyme Activities in Korean Native Cattle infested with Fasciola hepatica)

  • 위성하;박승주;이정길
    • 대한수의학회지
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    • 제28권1호
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    • pp.165-168
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    • 1988
  • Some hematological and biochemical indices were assayed in Korean native cattle naturally harbouring Fasciola hepatica infection and compared with uninfected controls. Affected animals revealed reduction in total erythrocyte count and hemoglobin content, and increase in total leukocyte count. Infected cattle had significantly lower levels of serum total protein, serum albumin and magnesium. Significantly higher values were obtained for the serum enzymes aspartate aminotransferase and alanine aminotransferase.

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Effect of Supplementation of Antioxidant Nutrient Against Oxidant Stress during Exercise

  • Kim, Hye-Yount
    • Journal of Nutrition and Health
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    • 제30권9호
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    • pp.1061-1066
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    • 1997
  • This study was undertaken to evaluate the effect of 4 weeks of $\alpha$-tocopherol(800 I.U./d) supplementation on oxidant stress of eleven female aerobic -majoring students during rest and exercise. Changes in the activity of the antioxidant enzyme glutathione peroxidase were also studied. Serum $\alpha$-tocopherol concentration was significantly increased with vitamin E supplementation(710.1$\pm$113.8$\mu\textrm{g}$/dl vs. 1,485,8$\pm$105.2$\mu\textrm{g}$/dl). In addition, serum MDA concentration, an index of lipid peroxidation, significantly decreased after vitamin E supplementation. However, MDA values after exercise increased to pre-supplementation levels. Serum glutathione peroxidase activity significantly increased with vitamin E supplementation. The enzyme activity showed a trend toward decrease after exercise. Serum cholesterol values were not significantly affected by vitamin E supplementation. However, serum triglycerides significantly increased after supplementation against oxidative stress during resting periods. These supplements appraently work by decreasing lipid peroxidation and increasing glutathione peroxidase activity. However, vitamin E supplementation did not prevent exercise-induced increases in lipid peroxidation.

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정상식과 채식을 하는 여대생의 영양상태에 관한 연구 (The Nutritional Status of Female Collegian on Normal Diet and Lacto-Ovo-Vegetarian)

  • 최미영;여정숙;강명춘;승정자
    • Journal of Nutrition and Health
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    • 제18권3호
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    • pp.217-224
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    • 1985
  • The purpose of this study is to discribe the nutritional status between female collegians on normal diet and lacto-ovo-vegetarian in the child bearing age. Physical examination, hematological parameters(hemoglobin, hematocrit, serum iron, serum albumin)and nutrient intake by dietary survey were carried out on each subject. Serum zinc, iron and copper concentrations were also determined. The results are summarized as follows : 1) Students on normal diet had higher values than lacto-ovo-vegetarian students in the height, weight, and skinfold thickness. 2) Hemoglobin, hematocrit, serum albumin values of the two groups showed no difference. But students on normal diet were higher in the serum irom and copper values than lacto-ovo-vegetarian students. 3) Serum zinc values differed significantly between the vegetarians and non vegetarians (Vegetarians') > non vegetarians') 4) On the nutrient intake of two groups, students on normal diet were higher than lacto-ovo-vegetarian students in the protein but students on normal diet were lower than lacto-ovo-vegetarian students in iron, vitamin A, $vitamin\;B_{2}$, vitamin C and crude fiber. 5) Intakes of calories and protein in the two groups were lower than RDA but Ca, vitamin A, $vitamin\;B_{1}$, $vitamin\;B_{2}$ niacin and vitamin C intakes of the two groups was higher than RDA. 6) Amounts of iron absorbed showed no difference in the two groups. But iron absorption rate was higher in students on normal diet than lacto-ovo-vegetarian students.

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Ameroid Constrictor를 이용한 개에서의 단순 간외성 간문맥전신단락증의 치료 (Surgical Correction of Single Extrahepatic Portosystemic Shunt Using Ameroid Constrictor in a Dog)

  • 정성목;이충호;양정환;김완희;최민철;윤정희;이주명;권오경;남치주
    • 한국임상수의학회지
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    • 제18권4호
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    • pp.442-447
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    • 2001
  • A 2-year-old 4.0-kg female Shih Tzu with history of hematemesis and melena was referred to Veterinary Medical Teaching Hospital, Seoul national University for further evaluation and treatment. During physical examination, the dog revealed mild depression, dry mucous membrane and abdominal pain. Hematologic values were normal and serum chemical values showed increased serum bile acid (53.47 umol/l, preprandial), fasting serum ammonia concentration (184 g/dl), alanine transferase (98 U/L), alkaline phosphatase (871 U/L) and gamma glutamyl transpeptidase (21 U/L), and decreased blood urea nitrogen (4 mg/dl), total protein (4.1 g/dl) and albumin (1.2 g/dl). Microhepatica was shown in abdominal radiography. During the ultrasound examination, dilated tortuous vein communicating with caudal vena cava ws observed near the stomach. Intraoperative jejunal vein portography was performed during laparotomy to confirm the location and size of shunt vessel. According to history taking, physical examination, hematologic and serum chemical examination and radiographic study, it was diagnosed as single extrahepatic portosystemic shunt. The anomalous vessel (7 mm, o.d.) that enter the caudal vena cava from the left gastric vein, near the level of the diaphragm, was identified. A Ameroid constrictor (5 mm, i.d.) was applied to the shunting vessel near the caudal vena cava. Hematologic and serum chemical values recovered gradually and were revealed normal values 4 months after surgery. Four month after surgery serum bile acids concentrations were 0.56 $\mu$mol/l (preprandial) and 18.45 umol/l (postprandial). Abdominal radiograph showed normal gastric axis and it revealed normal size of the liver. Fine texture and increased echogenecity of liver and enlargement of portal vein were shown in ultrasonography. Single extrahepatic portosystemic shunt might be treated surgically using Ameroid constrictor.

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임신유우(姙娠乳牛) 혈청(血淸)의 총(總) Calcium 및 무기인(無機燐) 농도(濃度)에 관하여 (Concentrations of Total Calcium and Inorganic Phosphorus in Blood Serum from Pregnant Holstein Cows)

  • 조충호;용만중
    • 대한수의학회지
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    • 제15권2호
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    • pp.181-185
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    • 1975
  • The experiment was carried out to determine the concentrations of total calcium and inorganic phosphorus of thirty rera obtained from pregnant Holitein cows, six sera from normal non-pregnant cows with one month after delivery, six sera from cows with ovarian cyst and six sera from heifer of sixteen months old. The changes of total calcium and inorganic phosphorus were observed on the 2nd, 4th, 6th, 8th, and l0th month of gestation. The results obtained in this work were summarized as follows: 1. The mean values of total serum calcium obtained from the pregnant group were $9.59{\pm}0.34mg/100ml$, from the non-pregnant group $10.23{\pm}0.47mg/100ml$, from the infertility grou $10.37{\pm}0.27mg/100ml$, and from the heifer group $10.07{\pm}0.20mg/ml$. The change of total serum calcium values in the pregnant group revealed the tendency of decrease as gestation progresses and the lowest value appeared on the sixth month. The mean value of total serum calcium in the pregnant group was lower than those of the other groups, but the differences were not statistically significant. 2. The mean values of serum inorganic phosphorus obtained from the pregnant group were $5.82{\pm}0.31mg/100ml$, from the non-pregnant group $5.92{\pm}0.44mg/100ml$, from the infertility group $5.80{\pm}0.49mg/100ml$, and from the heifer group $5.10{\pm}0.32mg/100ml$. The change during pregnancy showed a slight fall and the lowest value appeared on the sixth month. The differences of serum inorganic phosphorus values between the pregnant group and the other adult groups were not significant, but these adult groups showed a significantly higher value than that of heifer group (p<0.05).

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한국재래산양(韓國在來山羊)의 성장(成長)에 따르는 혈청화학치(血淸化學値)의 변동(變動) (Serum Chemical Values of Korean Native Goats from Birth to Maturity)

  • 문희철
    • 대한수의학회지
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    • 제15권2호
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    • pp.187-198
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    • 1975
  • Although considerable research has been done on the blood chemistry of domestic animals, little work has been made of the changes associated with age. Moreover, the records about physiology of the goat were not much available in Korea, and a comprehensive survey of the blood values of the Korean native goat has not been made. The object of the present investigation was to make good this deficiency and to suggest standards for the blood chemical values of Korean native goats from birth to maturity. The goats were kept under average farming conditions in Korea. Blood samples were collected from the jugular vein at birth, at one and four days, at one, two, three and four weeks, and at two, three, six, nine and twelve months of age. The results obtained in this work were summarized as follows: 1. The highest concentration of serum glucose was observed at birth and it decreased gradually until three months of age, showing a steady state thereafter. 2. The concentration of total serum protein was a little higher at one day of age than at birth and showed a steady state until seven days of age; then it decreased slightly at two weeks of age and recovered at three weeks of age and showed a steady state until twelve months of age. The concentration of serum albumin was increased a little at one day of age and revealed a steady state thereafter. The concentration of serum globulin showed three phases - a fall during the first two weeks to reach minimum, a rise to the fourth week, and a fall at two months of age, showing a steady state thereafter. The lowest value of albumin fraction was observed at birth, then the value increased gradually until three months of age and revealed a stealer state thereafter. The highest value of globulin fraction was observed at birth, then the gradual decrease of the value was seen until three months of age; thereafter the value showed a steady state. 3. Albumin/globulin ratio was the minimum at birth, then it increased to reach a maximum at two weeks of age and decreased a little thereafter. 4. The concentration of total serum cholesterol showed a gradual increase during the first three months and fell to reach adult revel at six months of age. 5. Urea nitrogen in serum decreased during the first week to reach a minimum, then it increased at three months of age, and showed a fell to mature level at six mouths of age. 6. The concentration of serum creatinine was not affected by age. 7. The concentration of total serum calcium was a little higher during the first two weeks than the other period during the first year of life. 8. The concentration of serum inorganic phosphorus showed a gradual rise to reach a maximum and a gradual fall to reach adult level at nine months of age. 9. No significant sex differences of serum chemical values were recognized.

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