• Title/Summary/Keyword: serum cortisol

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The Relationship between Oxidative Stress and Oxidative Markers

  • Park, Shin-Young;Lee, Sang-Pyung
    • Korean Journal of Clinical Laboratory Science
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    • v.46 no.1
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    • pp.31-37
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    • 2014
  • Metabolic syndrome such as, hypertension, diabetes, obesity, dyslipidemia etc are well known lifestyle diseases which threaten a health state. The purpose of this study is to evaluate antioxidant status and reactive oxygen species (ROS) in various stressful conditions. A group of persons (n=28) were enrolled in this study and stress status was evaluated using questionnaire of psychological well-being index (PWI-SF) and hematologic analysis of free oxygen radical defense (FORD), free oxygen radical test (FORT), lipid profiles and serum cortisol level. Analysis was done according to stress index, BMI status and overtime working. Blood samples from diabetics were used for control. Results are as in followings: Higher PWI-SF group showed higher FORT. Obese persons with BMI > $25kg/m^2$ showed statistically lower FORD (p<0.05) and higher FORT level (p<0.01). When compare with diabetics, an overweight group had similar levels in FORD and FORT while a normal body weight group showed quite different with diabetics in FORD (p<0.001). Higher ROS group has higher triglyceride, CRP and insulin levels but lower in FORD and HDL-cholesterol levels. Overtime working at night showed no meaningful result against our expectations. These results suggested that obesity showed most unfavorable correlations in an antioxidant status in various situations.

Monitoring of Blood Cytokines by PIT-1 Genotypes in Day 150 Male Pigs

  • Yoon, J.;Rhee, M.S.;Seo, D.S.;Kim, B.C.;Ko, Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.12
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    • pp.1659-1664
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    • 2001
  • Several studies have been done regarding carcass traits and growth in pigs. Recently, these have progressed to examine increases in economic traits, including meat quality and meat quantity, by using candidate genes. One of them is the pituitary-specific protein PIT-1, a member of the POU (Pit-Oct-Unc) family of transcription factors playing an important regulatory role in developmental processes. In addition, muscle development is known to be regulated in part by growth factors and cytokines locally produced. Therefore, studies were performed to analyze PIT-1 genotypes and serum cytokines (IGF-I, IGF-II, TGF-${\beta}1$, EGF, cortisol, DHEA-S, IL-2, and IL-6) in castrated male pigs for their possible involvement in the development of carcass traits. The genotypes of PIT-1 gene were analyzed by PCR-RFLP with MspI restriction enzyme. But, only CD and DD genotypes, not CC genotype, have been detected. Based on PIT-1 genotyping, a significant difference in EGF expression beween CD type (78.8 ng/ml) and DD type (46.0 ng/ml) was detected (p<0.05), whereas other cytokines did not show any statistical significance depending on PIT-1 genotypes. Collectively, these results suggest the possibility that EGF could affect the formation of carcass traits.

Effect of Progressive Muscle Relaxation using Biofeedback on Perceived Stress, Stress Response, Immune Response and Climacteric Symptoms of Middle-Aged Women (바이오피드백을 이용한 점진적 근육이완이 중년여성의 지각된 스트레스, 스트레스반응, 면역반응 및 갱년기 증상에 미치는 효과)

  • 정인숙
    • Journal of Korean Academy of Nursing
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    • v.34 no.2
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    • pp.213-224
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    • 2004
  • Purpose: This study was aimed to evaluate the effect of progressive muscle relaxation training using biofeedback on perceived stress, stress response, immune response and climacteric symptoms, Method: This was a crossover, pre-post test design, The study subjects are 36 middle-aged women who were selected at 2 public health centers, The independent variable was Biofeedback training for 4 weeks, twice a week and home training for 4 weeks, Dependent variables were perceived stress, stress response, immune response, and climacteric symptoms measured with Hildtch's scale (1996), Result: Progressive muscle relaxation training using biofeedback was not effective in reducing perceived stress, but it was shown to be effective in reducing physiological stress responses such as pulse rate and EMG, Though blood pressure and skin conductance were repeatedly down, and skin temperature slowly increased, there were no statistically significant differences. Progressive muscle relaxation training using biofeedback was not effective in reducing serum cortisol, enhancing immune responses, or decreasing climacteric symptoms. Conclusion: The findings point to a pressing need for further, well-controlled and designed research with consideration in selection of subjects and instruments, frequency of measurements, the sampling method, and intervention modalities.

Rewarming Intervention Program for Abdominal Surgery Patients (복부 수술 환자의 저체온 예방 중재 프로그램)

  • Ahn, Hye-Young;Eom, Mi-Ran
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.17 no.2
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    • pp.220-230
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    • 2010
  • Purpose: This study was done to identify differences in three groups of operative patients (Forced Air Warming, Electrical Blanketrol, Control) for discomfort and pattern of body temperature during surgery and post operatively. Methods: The sample consisted of 3 randomized 3 groups of abdominal surgery patients admitted to an university hospital in D-city : The Bair Hugger and upper body blanket were used with the first group, electrical blanketrol with PVC Film with the second, and the third group was the control. ANOVA was used with the WIN SPSS 17.0 program to analyze the data. Results: Significant differences were found among the three groups for tympanic and esophageal body temperature at 1 hour after starting surgery. There was significant difference in tympanic body temperature during the 15 minute stay in the post anesthetic room. There were no significant differences in thermal discomfort while in the post anesthetic room. or There among the three groups for serum cortisol during surgery. Conclusion: According to the results of this study, application of a Bair Hugger or electrical blanketrol improves maintenance of body temperature of operative patients as well as body temperature of post operative patients, and is a clinically significant warming method providing a more consistent body temperature.

Effect of a Randomized Controlled Trial Walking Program on Walking, Stress, Depressive Symptoms and Cardiovascular Biomarkers in Elderly Korean Immigrants

  • Sin, Mo-Kyung;Ibarra, Brandon;Tae, Thomas;Murphy, Patrick J.M.
    • Journal of Korean Biological Nursing Science
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    • v.17 no.2
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    • pp.89-96
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    • 2015
  • Purpose: Despite well-known benefits of walking on cardiovascular health, no structured walking exercise program has been formally tested on elderly Korean immigrants (EKIs). This pilot randomized controlled trial study assessed the effect of a walking program on walking behavior (pedometer steps count), stress (cortisol), depressive symptoms (CESD-10), and cardiovascular disease biomarkers (hs-CRP and fibrinogen) via venipuncture in EKIs. Methods: Seventy EKIs recruited from a Korean community were randomly assigned to a 12-week walking group or control group in a 3:2 ratio. The working program included a pedometer, buddy, monthly coffee card, weekly call for goal setting, and physical activity consultation. Walking group EKIs maintained the Centers for Disease Control and Prevention recommended exercise guidelines and good mental health status over 12 weeks. Results: There was no significant difference in the outcomes between control and walking groups. Conclusion: Social networking with Koreans in the senior center and church from a well-established Korean community might have positive effects on mental health.

Effects of Photoperiods and Body Size on the Off-season Smolt Production of Atlantic Salmon Salmo salar in a Recirculating Aquaculture System (순환여과양식시스템에서 광주기 및 어체 크기가 대서양연어(Salmo salar)의 Off-season Smolt 생산에 미치는 영향)

  • Kim, Youhee;Kim, Pyong Kih
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.55 no.6
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    • pp.894-902
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    • 2022
  • This study investigated the effects of photoperiod (NL 12L:12D and LL 24L:0D) and body sizes (30 g and 50 g) on parr-smolt transformation, post-smolt growth and blood properties in the off-season parr-smolt stage of Atlantic salmon reared in a recirculating aquaculture system (RAS). Potential off-season salmon smolt were reared in a freshwater RAS for 80 days and then all experimental fish were transferred to seawater. In both LL groups (LL-30 and LL-50), we recorded and increase in specific growth rate and reduction in feed conversion, although there were no significant difference in body size. The values of osmolality, and serum Na+, Cl- and cortisol concentrations in the LL groups were maintained at lower levels than in NL group fish, and LL group fish were observed to recover to the pre-seawater adaptation state more rapidly than those in the NL group. ID chips were inserted in all smolts reared in freshwater. These fish were subsequently transferred to full-strength seawater and thereafter individual growth rates were monitored for 120 days. The results indicated that compared with smolt reared under natural photoperiodic condition, 24 h lighting in freshwater contributed to enhancing post-smolt specific growth rate in seawater.

Effects of Nature-Based Programs for Workers in Korea: A Systematic Review

  • Shin, Jong-Yeon;Shin, Won-Sop
    • Journal of People, Plants, and Environment
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    • v.23 no.2
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    • pp.125-138
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    • 2020
  • The aim of this study was to review previous literature to determine the effects of nature-based program for workers. This systematic review was conducted in accordance with National Evidence-based Healthcare Collaborating Agency's guidance for undertaking systematic reviews for intervention. Literature search was performed using National Assembly Digital Library, Korean Studies Information Service System, and Korea Education & Research Information Service for literature published until March 2019. The participants were full-time workers, and intervention of nature-based programs was conducted in the outdoor, indoor, and indirect nature contact exposures, with comparators in the control group who did not receive the treatment. The results showed that the programs were effective in physical, psychological, and social health. The methodological quality of randomized controlled trials (RCT) was assessed using the Cochrane Risk of Bias(RoB) tool, while non-randomized controlled trials (N-RCT) were assessed using the Cochrane Risk of bias assessment tool for non-randomized studuies (RoBANS). A total of 16 studies were selected for assessment: two RCTs, 10 N-RCTs, and four one-group pretest-posttest designs. Most interventions were provided at the workplace and in the community. There were many kinds of nature-based interventions, and forest therapy and horticultural therapy programs were most common. Various interventions for workers effectively improved job stress, depression, serum cortisol and stress-response. However, the included studies lacked methodological rigor. Future research is needed to evaluate the long-term effectiveness of nature-based programs for workers using rigorous research designs.

The Effects of a Combination Program of Merdian Massage and Foot Reflexology on Stress and Natural Killer Cell Activity (경락마사지와 발반사마사지 병행 프로그램이 스트레스와 자연살해세포의 활동량에 미치는 효과)

  • Lee, Young-Mee
    • Journal of East-West Nursing Research
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    • v.16 no.2
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    • pp.190-198
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    • 2010
  • Purpose: The purpose of this study was to evaluate the effects of a combination program of meridian massage and foot reflexology on stress and natural killer (NK) cell activity in adults. Methods: This study is a quasi-experimental research usingone-group-pretest-posttest design. The subjects of the study were 42 adults in T city. Stress level was assessed with systolic blood pressure, diastolic blood pressure, pulse rate, and serum cortisol level. The data were analyzed by SPSS/WIN 17.0 program with descriptive statistics and Wilcoxon signed-rank test. The period of this study was from January 4 to July 11 of 2008. The program was performed three days per week, two hours per session. Results: The degrees of perceived stress were significantly different while objective stress levels were partially different between pre-and post-program. The NK cell activity did not show a significant difference between before and after the program. Conclusion: This study suggests that combination of meridian massage and foot reflexology may be an optional nursing intervention to reduce subjective and objective stress in adults.

Effects of Laughter Therapy on Mood, Pain, and Stress of Mastectomy Patients (웃음치료가 유방절제술 환자의 기분, 통증 및 스트레스에 미치는 효과)

  • Choi, Jeong Hwa;Kim, Kyung Hee;Cha, Soon Jung;Pyo, Hye Jung;Kim, Yeong Kyeong
    • Journal of Korean Clinical Nursing Research
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    • v.16 no.1
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    • pp.83-93
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    • 2010
  • Purpose: This study identified effects of laughter therapy administered to mastectomy patients as an adaptive coping mechanism. Methods: The study design was a non-synchronized design with a non-equivalent control group. Participants were 40 patients admitted to S hospital in Busan from July 1 to October 10, 2008. The laughter therapy was provided to the experimental group for 20 minutes, four times per week for 2 weeks in each patient's room. Results: The experimental and control groups showed significant differences in Mood (t=-2.314, p=.032), and Stress (t=-2.535 p=.020). Pain and serum cortisol in the experimental and control groups did not show any significant difference. Conclusion: Based on the findings the laughter therapy has significant effects on mastectomy patients' mood and stress.

The Effects of Dietary $MgSO_4$ Supplement on Serum Stress Hormones Concentrations and Pork Quality in Late Finishing Pigs (출하 전 마그네슘 단기급여가 돼지의 혈중 스트레스 관련 호르몬 함량 및 육질에 미치는 영향)

  • Seong Pil-Nam;Lee Jong-Eun;Cho In-Chul
    • Food Science of Animal Resources
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    • v.25 no.1
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    • pp.66-70
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    • 2005
  • This study was conducted to determine the effects of MgSO₄ supplement on meat quality and serum stress hormones concentrations in late finishing pigs. Sixty castrated Landrace pigs (average weight±S.D., 106.5±8.9 kg) were assigned to a control diet (without MgSO₄ supplement) and diet with MgSO₄(10 g/kg diet) supplemented. Pigs had free access to diets and water during five-day feeding period. At the end of feeding experiment, pigs were fasted for 16 hours and transported to commercial slaughter plant (30-minute transportation distance). After 2-hour lairage time, pigs were slaughtered, and blood samples were collected at bleeding procedure of slaughter. Pigs fed the diet with MgSO₄ supplement had higher (p<0.05) serum magnesium concentrations than those in pigs fed a control diet. Serum adrenaline, noradrenaline and cortisol concentrations determined at slaughter were not significantly different between dietary groups. Carcass temperature, pH at 24h post- slaughter, drip loss and color characteristics were not influenced (p>0.05) by short-term supplement of MgSO₄. Pigs fed the diet supplemented with MgSO₄ diet had lower PSE incidence (23.3%) compared to pigs fed the control diet (33%). These results indicate that short-term supplement of dietary MgSO₄ in late finishing pigs may not be beneficial in improving pork quality, and further study needs to assess feeding regime of magnesium supplement.