• Title/Summary/Keyword: series model

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The Prognostic Value of the Preoperative Lymphocyte Count in Patients with Gastric Cancer (위암환자에서 수술 전 말초혈액 림프구 수와 예후)

  • Kang, Shin-Yong;Yu, Wan-Sik;Chung, Ho-Young;Park, Sung-Hun
    • Journal of Gastric Cancer
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    • v.9 no.1
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    • pp.26-30
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    • 2009
  • Purpose: The aim of this study was to evaluate the prognostic value of the peripheral blood lymphocyte count before surgery in those patients with gastric cancer. Materials and Methods: The study group was comprised of a series of 1,054 patients who underwent curative gastrectomy. The appropriate lymphocyte count cutoff value was determined. The prognostic factors were evaluated by univariate and multivariate analyses. Results: The lymphocyte count cutoff value was 1,500/ul. The patients were classified into two groups: Group A had a lymphocyte count $\geq$ 1,500/ul (n=765) and Group B had a lymphocyte count <1,500/ul (n=289). There were statistically significant differences between the groups according to their age (P<0.001), the tumor stage (P=0.038) and the tumor size (P<0.001). The 5- and 10-year survival rates of Group A were 80.1% and 76.6%, respectively and those of Group B were 72.4% and 63.5%, respectively (P=0.002). When multivariate analysis was performed by the Cox proportional hazards model, the lymphocyte count was not an independent prognostic factor. Conclusion: Although the prognosis of patients with a high lymphocyte count was better than that of the patients with a low lymphocyte count, our results did not support using the preoperative peripheral blood lymphocyte count as an independent prognostic factor for patients with gastric cancer.

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A Comparative Study on Degradation of BTEX Vapor by O3/UV, TiO2/UV, and O3/TiO2/UV System with Operating Conditions (운전조건에 따른 O3/UV, TiO2/UV 및 O3/TiO2/UV 시스템의 BTEX 증기처리에 관한 비교 연구)

  • Kim, Kyoung-Jin;Park, Ok-Hyun
    • Journal of Korean Society for Atmospheric Environment
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    • v.24 no.1
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    • pp.91-99
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    • 2008
  • A multilayer tower-type photoreactor, in which $TiO_2$-coated glass-tubes were installed, was used to measure the vapor-phase BTEX removal efficiencies by ozone oxidation ($O_3$/UV), photocatalytic oxidation ($TiO_2$/UV) and the combination of ozone and photocatalytic oxidation ($O_3/TiO_2$/UV) process, respectively. The experiments were conducted under various relative humidities, temperatures, ozone concentrations, gas flow rates and BTEX concentrations. As a result, the BTEX removal efficiency and the oxidation rate by $O_3/TiO_2$/UV system were highest, compared to $O_3$/UV and $TiO_2$/UV system. The $O_3/TiO_2$/UV system accelerated the low oxidation rate of low-concentration organic compounds and removed organic compounds to a large extent in a fixed volume of reactor in a short time. Therefore, $O_3/TiO_2$/UV system as a superimposed oxidation technology was developed to efficiently and economically treat refractory VOCs. Also, this study demonstrated feasibility of a technology to scale up a photoreactor from lab-scale to pilot-scale, which uses (i) a separated light-source chamber and a light distribution system, (ii) catalyst fixing to glass-tube media, and (iii) unit connection in series and/or parallel. The experimental results from $O_3/TiO_2$/UV system showed that (i) the highest BTEX removal efficiencies were obtained under relative humidity ranging from 50 to 55% and temperature ranging from 40 to $50^{\circ}C$, and (ii) the removal efficiencies linearly increased with ozone dosage and decreased with gas flow rate. When applying Langmuir-Hinshelwood model to $TiO_2$/UV and $O_3/TiO_2$/UV system, reaction rate constant for $O_3/TiO_2$/UV system was larger than that for $TiO_2$/UV system, however, it was found that adsorption constant for $O_3/TiO_2$/UV system was smaller than that for $TiO_2$/UV system due to competitive adsorption between organics and ozone.

Metal Matrix Composite(MMC) Layered Armour System (금속복합판재 적용 다층 구조 방호성능 평가)

  • Lee, Minhyung;Park, Sang-Won;Jo, Ilguk
    • Journal of the Korea Institute of Military Science and Technology
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    • v.20 no.6
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    • pp.752-757
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    • 2017
  • Analysis has been performed for the penetration of a long-rod into MMC/Ceramic layered armour system with several shot test and a series of simulations. Two types of MMC plate have been fabricated by a liquid pressing method; A356/45%vol.%SiCp with a uniform distribution of SiC particle and Al7075/45%vol.B4Cp with B4C particle. The mechanical properties were measured with the high-speed split Hopkins bar test, hardness test and compression test. The popular Simplified Johnson-Cook model was adopted to represent the material characteristics for FEM simulations. The performance of the MMC applied armour system has been made by comparing with the semi-infinite mild steel target using the depth of penetration(DOP). The results show that placing ceramic front layer provides a certain gain in protection, and that placing another ductile front layer provides a further gain. The application of MMC is found to be attractive.

A binary adaptive arithmetic coding algorithm based on adaptive symbol changes for lossless medical image compression (무손실 의료 영상 압축을 위한 적응적 심볼 교환에 기반을 둔 이진 적응 산술 부호화 방법)

  • 지창우;박성한
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.22 no.12
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    • pp.2714-2726
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    • 1997
  • In this paper, adaptive symbol changes-based medical image compression method is presented. First, the differenctial image domain is obtained using the differentiation rules or obaptive predictors applied to original mdeical image. Also, the algorithm determines the context associated with the differential image from the domain. Then prediction symbols which are thought tobe the most probable differential image values are maintained at a high value through the adaptive symbol changes procedure based on estimates of the symbols with polarity coincidence between the differential image values to be coded under to context and differential image values in the model template. At the coding step, the differential image values are encoded as "predicted" or "non-predicted" by the binary adaptive arithmetic encoder, where a binary decision tree is employed. The simlation results indicate that the prediction hit ratios of differential image values using the proposed algorithm improve the coding gain by 25% and 23% than arithmetic coder with ISO JPEG lossless predictor and arithmetic coder with differentiation rules or adaptive predictors, respectively. It can be used in compression part of medical PACS because the proposed method allows the encoder be directly applied to the full bit-planes medical image without a decomposition of the full bit-plane into a series of binary bit-planes as well as lower complexity of encoder through using an additions when sub-dividing recursively unit intervals.

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Genome-Wide Association Analyses on Blood Pressure Using Three Different Phenotype Definitions

  • Park, Ji-Wan;Uhmm, Saan-Yong;Shin, Chol;Cho, Nam-H.;Cho, Yoon-Shin;Lee, Jong-Young
    • Genomics & Informatics
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    • v.8 no.3
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    • pp.108-115
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    • 2010
  • Hypertension is the most prevalent disease worldwide and is itself a risk factor for cerebral, cardiac, and renal diseases. The inconsistency of candidate genes suggested by previous genomewide association studies (GWASs) may be due to not only differences in study design and genetic or environmental background but also the difference in the power of analysis between continuous traits and discrete traits. We analyzed 352,228 single nucleotide polymorphisms (SNPs) in 8842 unrelated Koreans obtained from Ansan and Ansung cohorts. We performed a series of GWA analyses using three different phenotype models; young hypertensive cases (278 subjects) versus elderly normotensive controls (680 subjects); the upper 25% (2211 hypertensive cases) versus the lower 25% of the SBP distribution (2211 hypotensive controls); and finally SBP and DBP as continuous traits (8842 subjects). The numbers of young hypertensive cases and elderly normotensive controls were not large enough to achieve genomewide significance. The model comparing the upper 25% subjects to the lower 25% of subjects showed a power that was approximate to that of QTL analysis. Two neighboring SNPs of the ATP2B1 gene, rs17249754 (SBP, p=$2.53^{-10}$; DBP, p=$1.28{\times}10^{-8}$) and rs7136259 (SBP, p=$1.30{\times}10^{-9}$; DBP, p=$6.41{\times}10^{-8}$), were associated with both SBP and DBP. Interestingly, a SNP of the RPL6 gene, rs11066280, revealed a significant genomewide association with SBP in men only (p=$3.85{\times}10^{-8}$), and four SNPs located near the MAN2A1 gene showed a strong association with DBP only in elderly men aged 60-70 years (e.g., rs6421827, p=$4.86{\times}10^{-8}$). However, we did not observe any gene variant attaining genomewide significance consistently in the three phenotype models except for the ATP2B1 gene variants. In general, the association signal with blood pressure was stronger in women than in men. Genes identified in GWASs are expected to open the way for prevention, early diagnosis, and personalized treatment of hypertension.

Estimation of kerosene demand function using time series data (시계열 자료를 이용한 등유수요함수 추정)

  • Jeong, Dong-Won;Hwang, Byoung-Soh;Yoo, Seung-Hoon
    • Journal of Energy Engineering
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    • v.22 no.3
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    • pp.245-249
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    • 2013
  • This paper attempts to estimate the kerosene demand function in Korea over the period 1981-2012. As the kerosene demand function provides us information on the pattern of consumer's kerosene consumption, it can be usefully utilized in predicting the impact of policy variables such as kerosene price and forecasting the demand for kerosene. We apply least absolute deviations and least median squares estimation methods as a robust approach to estimating the parameters of the kerosene demand function. The results show that short-run price and income elasticities of the kerosene demand are estimated to be -0.468 and 0.409, respectively. They are statisitically significant at the 1% level. The short-run price and income elasticities portray that demand for kerosene is price- and income-inelastic. This implies that the kerosene is indispensable goods to human-being's life, thus the kerosene demand would not be promptly adjusted to responding to price and/or income change. However, long-run price and income elasticities reveal that the demand for kerosene is price- and income-elastic in the long-run.

Slope Failure Predicting Method Using the Monitoring of Volumetric Water Content in Soil Slope (흙사면의 체적함수비 계측을 통한 사면파괴 예측기법 개발)

  • Kim Man-Il;Nishigaki Makoto
    • The Journal of Engineering Geology
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    • v.16 no.2 s.48
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    • pp.135-143
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    • 2006
  • This study presents the results of a series of laboratory scale slope failure experiments aimed at clarifying the process and the condition leading to the initiation of rainfall-induced slope failures. For the evaluation of hydrologic response of the model slopes in relation the process of failure initiation, measurements were focused on the changes in volumetric water content during the initiation process. The process leading to failure initiation commences by the development of a seepage face. It appears reasonable to conclude that slope failures are a consequence of the instability of seepage area formed at the slope surface during rainfall period. Therefore, this demonstrates the importance of monitoring the development seepage area for useful prediction about the timing of a particular failure event. The hydrologic response of soil slopes leading to failure initiation is characterized by three phases (phase I, II and III) of significant increase in volumetric water content in association with the ingress of wetting front and the rise of groundwater level within the slope. The period of phase III increase in volumetric water content can be used to initiate advance warning towards a failure initiation event. Therefore, for the concept outlined above, direct and continuous monitoring of the change in volumetric water content is likely to provide the possibility for the development of a reliable and effective means of predicting the occurrence of rainfall-induced slope failures.

Nitrogen and Phosphorus Removal Characteristics of a New Biological Nutrient Removal Process with Pre-Denitrification by Pilot Scale and Computer Simulation Program (선단무산소조를 이용한 영양소제거공정(Bio-NET)의 질소·인 제거 특성)

  • Oh, Young-Khee;Oh, Sung-Min;Hwang, Yenug-Sang;Lee, Kung-Soo;Park, No-Yeon;Ko, Kwang-Baik
    • Journal of Korean Society of Environmental Engineers
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    • v.22 no.1
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    • pp.121-132
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    • 2000
  • This study is to investigate the performance of a new BNR process using predenitrification scheme focusing on nitrogen removal and the possibility of adapting a computer simulation scheme in BNR process development. By using a pre-denitrification basin, higher $COD/NO_3-N$ ratio could be sustained in this BNR process. The results of the investigation showed a SDNR value of 9.04mg/gMv/hr. In the anoxic tank, the average value of SPRR of 6.25mgP/gMv/hr was observed to be very sensitive to SCOD load of influents. By calibrating internal parameters (stoichiometric and kinetic parameters) of the simulation model, the results of simulation for various BNR processes gave good agreement with observed data. The major adjustment was given with three parameters, maximum specific growth rate of heterotrophic biomass, short chain fatty acid (SCFA) limit, and phosphorous release rate. With the series of simulations on varying operational conditions, the simulation by computer program can be a useful tool for process selection, and design and operation of municipal wastewater treatment plant.

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3-D Crustal Velocity Tomography in the Southern Part of The Korean Peninsula (한반도 남부지역의 3-D 속도 토모그래피)

  • Kim, So Gu;Li, Qinghe
    • Economic and Environmental Geology
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    • v.31 no.2
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    • pp.127-139
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    • 1998
  • A new technique of simultaneous inversion for 3-D seismic velocity structure by using direct, reflected, and refracted waves is applied to the southeast part of the Korean Peninsula including Pohang Basin, Kyongsang Basin and Ryongnam Massif. Pg, Sg, PmP, SmS, Pn, and Sn arrival times of 44 events with 554 seismic rays are inverted for locations and crustal structure. $6{\times}6$ with $0.5^{\circ}$ and 8 layers (4 km each layer) model was inverted. 3-D seismic crustal velocity tomography including eight sections from surface to Moho, ten profiles along latitude and longitude are analyzed. The results are as follows: 1) the average velocity and thickness of sediment are 5.04 km/s and 3-4 km, and the velocity of basement is 6.11 km/s. The shape of velocity in shallower layer is agreement with Bouguer gravity anomaly (Cho et al., 1997). 2) the velocities fluctuate strongly in the upper crust. The velocity distribution of the lower crust under Conrad appears basically horizontal. 3) the average depth of Moho is 30.4 km, and velocity is 8.01 km/s. 4) from the velocity and depth of the sediment, the thickness, velocity and form of the upper crust, and the depth and form of Moho, we can find the obvious differences among Ryongnam Massif, Kyongsang Basin and Pohang Basin. 5) the deep faults (a Ulsan series faults) near Kyongju and Pohang areas can be found to be normal and/or thrust faults with detachment extended to the bottom of the upper crust.

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Depth Image Poselets via Body Part-based Pose and Gesture Recognition (신체 부분 포즈를 이용한 깊이 영상 포즈렛과 제스처 인식)

  • Park, Jae Wan;Lee, Chil Woo
    • Smart Media Journal
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    • v.5 no.2
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    • pp.15-23
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    • 2016
  • In this paper we propose the depth-poselets using body-part-poses and also propose the method to recognize the gesture. Since the gestures are composed of sequential poses, in order to recognize a gesture, it should emphasize to obtain the time series pose. Because of distortion and high degree of freedom, it is difficult to recognize pose correctly. So, in this paper we used partial pose for obtaining a feature of the pose correctly without full-body-pose. In this paper, we define the 16 gestures, a depth image using a learning image was generated based on the defined gestures. The depth poselets that were proposed in this paper consists of principal three-dimensional coordinates of the depth image and its depth image of the body part. In the training process after receiving the input defined gesture by using a depth camera in order to train the gesture, the depth poselets were generated by obtaining 3D joint coordinates. And part-gesture HMM were constructed using the depth poselets. In the testing process after receiving the input test image by using a depth camera in order to test, it extracts foreground and extracts the body part of the input image by comparing depth poselets. And we check part gestures for recognizing gesture by using result of applying HMM. We can recognize the gestures efficiently by using HMM, and the recognition rates could be confirmed about 89%.