• The Journal of Internal Korean Medicine
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• v.29 no.1
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• pp.117-129
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• 2008

Background & Objective : Naeso-san(NSS) has been used for the treatment of functional dyspepsia, regarded as a gastric dysmotility disease. A main cause of gastric dysmotility is antral dilatation or antroduodenal uncoordination. Therefore, we investigated the effect of NSS on gastric motility and its mechanism of action, as well as the morphologic changes in antral dilatated rats. Methods : Antral dilatated rats were induced by wrapping a nonabsorbable rubber ring(D:6mm, W:4mm, T:1mm) around the 1st portion of the duodenum for 8 weeks. Then morphologic changes were investigated and compared with normal intact rats before and after 8 weeks. Gastric emptying was measured by administration of normal saline(NS) or NSS in normal intact and antral dilatated rats. In another series of experiments to evaluate the mechanism of NSS under delayed conditions, normal intact rats were treated with atropine sulfate(1mg/kg, s.c.), quinpirole HCl(0.3mg/kg, i.p.), $NAME(N^{G}-nitro-L-arginine$ methyl ester, 75mg/kg, s.c.) and cisplatin(10mg/kg, i.p.), respectively. The myoelectrical activity of the gastric smooth muscle was recorded in normal intact and antral dilatated rats. The contractile waves were measured for 30 minutes before and after administration of each solution(NS, NSS). Results : Body weight gain of antral dilatated rats was significantly lower than that of the controls. Futhermore, we found the thickness of the mucosal and muscular layers and surface area of the stomach increased significantly compared with controls. NSS 278㎎/㎏ improved gastric emptying more than normal saline or NSS 93mg/kg in normal intact(p=0.026) and antral dilatated rats(p=0.03). NSS enhanced gastric emptying significantly in the NAME treated group(p=0.002). NSS 278mg/kg increased the significant postprandial dominant power than that of NS in normal intact rats, whereas there was no statistical significance in antral dilatated rats. Conclusions : NSS stimulates gastric motility through the cholinergic pathway. We expect that pathologic model with antral dilatation can be used as an exprimental tool which is similar to dyspepsia and NSS would be effective especially in dysmotility-like functional dyspepsia with antral dilatation or impaired reservoir functions such as gastric adaptive relaxation.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.37 no.2
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• pp.95-105
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• 2001

A series of experiment is carried out to determine the holding power of the existing anchors used in the stationary gear in the coast of the South sea. The experiment apparatus is made of the pulling machine, the load cell, the personal computer and three water tanks the bottom of which are mud, sand and m & s respectively. The result obtained are as follows : 1. On the tension and holding power of the existing anchors, B-type of the stock anchor with two fluke shows the greatest and gets smaller on order of A-type one with a fluke. The holding power of the anchors shows the greatest in the mud and gets smaller in order of m & s, sand. And, the holding power depending upon the length of anchor rope increase as the length does up to the 4 times of depth. 2. On the holding power per fluke area of the existing anchors in case of ration of length of anchor rope to depth is 2, 3 and 4, A-type anchor shows about 310-320 kg/m supper(2), 470-480 kg/m supper(2), 590-640 kg/m supper(2) respectively, B-type one 260-265 kg/m supper(2), 390-450 kg/m supper(2), 630-700 kg/m supper(2) respectively, and C-type one 70-100 kg/m supper(2), 150-180 kg/m supper(2), 210-270 kg/m supper(2) respectively. The holding power per fluke area of the anchors increase as the length of anchor rope does. 3. On the coefficient of holding power of the existing anchors, A-type anchor shows the greatest and gets smaller in the order of B-type one, C-type one.

• Journal of Society of Preventive Korean Medicine
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• v.21 no.2
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• pp.1-13
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• 2017

Objectives : This paper serves to explore current trends of systems biology in Traditional Chinese Medicine (TCM) and examine how it may influence the Traditional Korean medicine. Methods : Literature review method was collectively used to classify Introduction to systems biology, diagnosis and syndrome classification of systems biology in TCM perspective, physiotherapy including acupuncture, herbs and formula functions, TCM systems biology, and directions of academic development. Results : The term 'Systems biology' is coined as a combination of systems science and biology. It is a field of study that tries to understand living organism by establishing a theory based on an ideal model that analyzes and predicts the desired output with understanding of interrelationships and dynamics between variables. Systems biology has an integrated and multi-dimensional nature that observes the interaction among the elements constructing the network. The current state of systems biology in TCM is categorized into 4 parts: diagnosis and syndrome, physical therapy, herbs and formulas and academic development of TCM systems biology and its technology. Diagnosis and syndrome field is focusing on developing TCM into personalized medicine by clarifying Kidney yin deficiency patterns and metabolic differences among five patterns of diabetes and analyzing plasma metabolism and biomarkers of coronary heart disease patients. In the field of physical therapy such as acupuncture and moxibustion, researchers discovered the effect of stimulating acupoint ST40 on gene expression and the effects of acupuncture on treating functional dyspepsia and acute ischemic stroke. Herbs and formulas were analyzed with TCM network pharmacology. The therapeutic mechanisms of Si Wu Tang and its series formulas are explained by identifying potential active substances, targets and mechanism of action, including metabolic pathways of amino acid and fatty acid. For the academic development of TCM systems biology and its technology, it is necessary to integrate massive database, integrate pharmacokinetics and pharmacodynamics, as well as systems biology. It is also essential to establish a platform to maximize herbal treatment through accumulation of research data and diseases-specific, or drug-specific network combined with clinical experiences, and identify functions and roles of molecules in herbs and conduct animal-based studies within TCM frame. So far, few literature reviews exist for systems biology in traditional Korean medicine and they merely re-examine known efficacies of simple substances, herbs and formulas. For the future, it is necessary to identify specific mechanisms of working agents and targets to maximize the effects of traditional medicine modalities. Conclusions : Systems biology is widely accepted and studied in TCM and already advanced into a field known as 'TCM systems biology', which calls for the study of incorporating TCM and systems biology. It is time for traditional Korean medicine to acknowledge the importance of systems biology and present scientific basis of traditional medicine and establish the principles of diagnosis, prevention and treatment of diseases. By doing so, traditional Korean medicine would be innovated and further developed into a personalized medicine.

• Journal of Korea Water Resources Association
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• v.47 no.3
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• pp.297-306
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• 2014

In this study, EFDC (Environmental Fluid Dynamics Code) model was used to simulate the salinity distribution for sea water inflow and rainfall runoff. The flowrate was given to the boundary conditions, which can be calculated by areal-specific flowrate method from the measured flowrate of the representative outfall. The boundary condition of the water elevation can be obtained from the hourly tidal elevation. The flowrate from the outfall can be calculated using the condition of the 245 mm raifall. The simulation results showed that at Sites 1~2 and the Mangsan island (Site 4) the salinity becomes 0 ppt after the rainfall. However, the salinity is 30 ppt when there is no rainfall. Time series of the salinity changes were compared with the measured data from January 1 to December 31, 2010 at the four sites (Site 2~5) of Yongwon channel. Lower salinities are shown at the inner sites of Yongwon channel (Site 1~4) and the sites of Songjeong river (Site 7~8). The intensive investigation near the Mangsan island showed that the changes of salinity were 21.9~28.8 ppt after the rainfall of 17 mm and those of the salinity were 2.33~8.05 ppt after the cumulative rainfall of 160.5 mm. This means that the sea water circulation is blocked in Yongwon channel, and the salinity becomes lower rapidly after the heavy rain.

• Economic and Environmental Geology
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• v.42 no.2
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• pp.143-152
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• 2009

Recent raw material prices fluctuation has been unexpectedly high and that made Korean economic activities to be depressed. Because most raw material supply in Korea depends upon oversea imports, unexpected raw material price fluctuation affects Korean industrial economies through macroeconomic variables. So Korean government enforces some political measures such as demand management and the supply-security assurance as long-range policies, and reservation and general early warning system as short-range policies. In short-range policies, it is necessary to be expected short term fluctuation. Up to recently, there have been many researches and most of those researches use parametric methods or time series analyses. Because those methods and analyses often generate inadequate relations among variables, it is possible that some consistent variables are left out or the results are misunderstood. This study, therefore, is aim to mitigate those methodological problems and find the relatively appropriate model for economic explanation. So that, in this paper, by using non-parametric signal approach method mitigating some shortages of previous researches and forecasting properly short-range prices fluctuation of non-ferrous materials are presented empirically.

• Korean Journal of Environmental Agriculture
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• v.36 no.4
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• pp.293-298
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• 2017

BACKGROUND: Pyrethroids (PYRs) are a widely used insecticide in agriculture and household area. In mammals, PYRs such as deltamethrin is metabolized to 3-phenoxybenzoic acid (3-PBA) in liver that is mainly excreted in urine. This study is designed to single exposure of deltamethrin to rats in a dose-dependent manner and identify the correlation between deltamethrin exposure and its metabolite (3-PBA) in urine. METHODS AND RESULTS: Exposure levels of deltamethrin were control (0 mg/kg bw), low (0.0705 mg/kg bw), medium (0.705 mg/kg bw) and high (7.05 mg/kg bw) dose. Low concentration was derived by ussing Korea predictive operator exposure model (KoPOEM). Dermal exposure persisted for 6 h, and urine specimens were collected for 24 h. The urine matrix was removed after a series of procedures and 3-PBA was analyzed by gas chromatography/mass spectrometry. CONCLUSION: There was a strong correlation ($R^2=0.83$) between the amount of oral exposure to delta me thrin and urinary levelof3-PBAexcreted. In dermal exposure groups of deltamethrin except high-dose, also there was a good correlation between urinary 3-PBA and deltamethrin exposure, but not stronger than in oral deltamethrin exposure groups. Based on these results, therefore, the amount of 3-PBA in urine can be used as a good monitoring indicator that reflexing the exposure level of deltamethrin to human body.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.28 no.2
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• pp.265-271
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• 2010

This paper discusses a new software package, DEM_Comp, developed for effectively compressing large digital elevation model (DEM) data sets based on Lempel-Ziv-Welch (LZW) compression and Huffman coding. DEM_Comp was developed using the $C^{++}$ language running on a Windows-series operating system. DEM_Comp was also tested on various test sites with different territorial attributes, and the results were evaluated. Recently, a high-resolution version of the DEM has been obtained using new equipment and the related technologies of LiDAR (LIght Detection And Radar) and SAR (Synthetic Aperture Radar). DEM compression is useful because it helps reduce the disk space or transmission bandwidth. Generally, data compression is divided into two processes: i) analyzing the relationships in the data and ii) deciding on the compression and storage methods. DEM_Comp was developed using a three-step compression algorithm applying a DEM with a regular grid, Lempel-Ziv compression, and Huffman coding. When pre-processing alone was used on high- and low-relief terrain, the efficiency was approximately 83%, but after completing all three steps of the algorithm, this increased to 97%. Compared with general commercial compression software, these results show approximately 14% better performance. DEM_Comp as developed in this research features a more efficient way of distributing, storing, and managing large high-resolution DEMs.

• Journal of Korean Society for Atmospheric Environment
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• v.22 no.5
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• pp.661-678
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• 2006

Products developed in this research is a software which can transfer the type of shape(.shp) into the type of ascii using the land cover data and the topography data in the metropolitan area of Seoul. In addition, it can calculate the $CO_2$ flux according to distribution of plants within the land cover data. The $CO_2$ flux is calculated by the experimental equation which is compose of the meteorological parameters such as the solar radiation and the air temperature. The net flux was shown in about $-19ton/km^2$ by removing $CO_2$ through the photosynthesis during daytime, and in 2 ton/km2 by producing it through the respiration during nighttime on 10 August 2004, the maximum day of air temperature during the period of 3yr(2001 to 2004), in the metropolitan area of Seoul. Spatial distribution of the air temperature and the wind field is simulated by substituting the middle classification of the land cover map data, upgraded by the Korean Ministry of Environment(KME), for the land-use data of the United States Geological Survey(USGS) within the Meteorological Mesoscale Model Version 5(MM5) on 10 August 2006 in the metropolitan area of Seoul. Difference of the air temperature between both data was shown in the maximum range of $-2^{\circ}C\;to\;2.9^{\circ}C$, and the air temperature due to the land use data of KME was higher than that of USGS in average $0.4^{\circ}C$. Also, those of wind vectors were meanly lower than that of USGS in daytime and nighttime. Furthermore, the hourly time series of Volatile Organic Components(VOCs) is calculated by using the Biosphere Emission and Interaction System Version 2(BEIS2) including the new land cover data and the meteorological parameters such as the air temperature and so]ar insolation. It is possible to calculate the concentration of ozone due to the biogenic emission of VOCs.

• Journal of the Korean Geotechnical Society
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• v.28 no.8
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• pp.43-53
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• 2012

In the conventional design of a piled raft, the axial resistance offered by the raft itself is typically neglected and only that of the group pile is accounted in estimating the total axial resistance of the piled raft. As a consequence, piled rafts are usually designed conservatively by neglecting the raft resistance. In this study, a series of centrifuge model tests have been performed to compare the axial behavior of a group pile with that of a piled raft (both having 16 component piles with an array of $4{\times}4$) in sands with different relative densities and in clays with different preconsolidated pressures. The test results revealed that, with respect to the allowable settlement of 25 millimeters for bridge foundations, the piled raft resistances were greater than those of the group pile by 13% for dense sand, by 22% for loose sand, by 30% for stiff clay, and by 22% for soft clay. Furthermore, the ratio of piled raft resistance to group pile resistance increased as the settlement increased.

• Journal of Digital Contents Society
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• v.12 no.1
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• pp.85-94
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• 2011

QoS(Quality of Service) is defined as "The collective effect of service performance which determines the degree of satisfaction of a user of the service" by ITU-T Rec. E.800. While the use of VoIP(Voice Over Internet Protocol) has been widely implemented, persistent problems with QoS are a very important sue which needs to be solved. This research is finding the assignment of VoIP QoS to deduct how to manage the control system and presenting the QoS control process and framework under NGN(Next Generation Network) environment. The trial framework is the modeling of the QoS measurement metrics, instrument, equipment, method of measurement, the series of cycle & the methodology about analysis of the result of measurement. This research underlines that the vulnerability of the VoIP protocol in relation to its QoS can be guaranteed when the product quality and management are controlled and measured systematically. Especially it's very important time to maintain the research about VoIP QoS measurement and control because the big conversion of new network technology paradigm is now spreading. In addition, when the proposed method is applied, it can reduce an overall delay and can contribute to improved service quality, in relation to signal, voice processing, filtering more effectively.