The paper provides an inside look into experimental measurements, followed by numerical simulations and their related uncertainties. The goal of the paper is to present findings related to blast loading and the handling of defects that are inherent in experiments. Very often it might seem that experiments are simplified reflections of real-life conditions. In most cases this is true, but there is a good reason for that. The more complex an experiment is, the larger the amount of uncertainties that can be expected. This especially applies when the blast loading of concrete is the subject of research. When simulations fail to reproduce the results of experimental measurements, it does not necessarily mean there is something wrong with the numerical model. The problem could be missing information. Put differently, the numerical simulation may lack information that seemed irrelevant with regard to the experiment. In the presented case, a reference simulation with a proven material model unexpectedly failed to replicate the results of an experiment where concrete slabs were exposed to blast loading. This resulted in a search for possible unknowns. When all of the uncertainties were examined, the missing information turned out to be the orientation of the charge to the concrete slab. Since the experiment was burdened with error, a sensitivity study had to take place so the influence of this factor could be better understood. The findings point to the fact that even the smallest defect during experiments must somehow be taken into account when designing numerical simulations. Otherwise, the simulations are not correlated to the experiments, but merely to some expectations.
The continuous increase in the production of metals and their subsequent release into the environment has lead to increased concentration of these elements in agricultural soils. Because microbes are involved in almost every chemical transformations taking place in the soil, considerable attention has been given to assessing their responses to metal contaminants. Short-term and long-term exposures to toxic metals have been shown to reduce microbial diversity, biomass and activities in the soil. Several studies show that microbial parameters like basal respiration, metabolic quotient, and enzymatic activities, including those of oxidoreductases and those involved in the cycle of C, N, P and other elements, exhibit sensitivity to soil metal concentrations. These have been therefore, regarded as good indices for assessing the impact of metal contaminants to the soil. Metal contamination has also been extensively shown to decrease species diversity and cause shifts in microbial community structure. Biochemical and molecular techniques that are currently being employed to detect these changes are continuously challenged by several limiting factors, although showing some degree of sensitivity and efficiency. Variations and inconsistencies in the responses of bioindicators to metal stress in the soil can also be explained by differences in bioavailability of the metal to the microorganisms. This, in turn, is influenced by soil characteristics such as CEC, pH, soil particles and other factors. Therefore, aside from selecting the appropriate techniques to better understand microbial responses to metals, it is also important to understand the prevalent environmental conditions that interplay to bring about observed changes in any given soil parameter.
Journal of the Institute of Electronics Engineers of Korea TC
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v.47
no.3
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pp.39-49
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2010
Ad hoc network is infrastructureless network, that the network topology is configured by each node. Each node capacity device function namely, accomplishes a network control and a function of management because not being Network device of the exclusively. Ad hoc networks what kind of node join or leave the network topology to facilitate the expansion of arbitrary topology, to the case which is the distance whose traffic is distant the place must overtake through the route of intermediate nodes, like these facts give an effect to performance fluctuation. Consequently, each node in order to maintain traffic of oneself stably there is a necessity which will consider traffic and congestion control from the node which traffic of a condition and oneself of traffic of the circumference and the route which compose the network will overtake through. This paper assumes the path of the band with a finite resource, and path traffic to occupy the competition and its impact on transmission performance of these competing arguments to configure the model factor to analyse the performance impact on the results presented. Like this result with the fact that from the study, it will contribute in network management policy and the technique.
Journal of the Korean association of regional geographers
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v.22
no.4
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pp.912-930
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2016
This paper suggests to bring the idea of social construction of nature or social nature discussed in social science including geography to geographical and environmental education for breaking traditional divide of people(or society) and nature. And this paper analyzed relationship between people and nature, meaning of environment and the concepts of social nature represented in the geography curriculum and textbook of England, Australia and Korea. Recently in terms of focusing disciplines or education on integration or convergence, introduction of social nature in teaching and learning geography and environment has an important implication. With rapid growth of capitalism, nature is constructed socially by the political, economical, social and cultural practice. Thus geography education reduces the distance between human geography and physical geography and needs to focus on exploring not just the relationship between people and nature but social construction of nature. Another implication of the introduction of social nature in teaching and learning geography and environment is that students can develop the relational sensitivity about the relationship people and nature or people and place.
Food allergy represents a severe problem for many societies, including sensitive populations, academies, health authorities, and the food industry. Peanut allergy occupies a special place in the food allergy spectrum. To prevent consumption by consumers suffering from a peanut allergy, a rapid and sensitive detection method is essential to identify unintended peanut adulteration in processed foods. In this study, we produced four monoclonal antibodies (MAbs; RO 3A1-12, PB 4C12-10, PB 5F9-23, and PB 6G4-30) specific to thermo-stable and soluble proteins (TSSPs) of peanut and developed an enzyme-linked immunosorbent assay (ELISA) based on the MAbs. Among them, PB 5F9-23 MAb was firmly bound to Ara h 1, and other MAbs strongly reacted to Ara h 3 in the Western blot analysis. An antibody cocktail solution of the MAbs was used to enhance the sensitivity of an indirect ELISA, and the limit of detection of the indirect ELISA based on the antibody cocktail solution was 1 ng/ml and improved compared to the indirect ELISA based on the single MAb (11 ng/ml). The cross-reaction analysis revealed the high specificity of developed MAbs to peanut TSSPs without cross-reaction to other food allergens, including nuts. Subsequently, analyzing processed foods by indirect ELISA, all foods labeled as containing peanuts in the product description were confirmed to be positive. The results indicate that the developed antibodies exhibit high specificity and sensitivity to peanuts and can be used as bio-receptors in immunoassays or biosensors to detect intentional or unintentional adulteration of peanuts in processed foods, particularly heat-processed foods.
This study analyzes the variable consumer characteristics that influence the intention to use online product reviews. In online e-commerce, where purchases take place without consumers seeing the products in person, the product reviews left by other consumers who have already purchased the product are believed to be valuable information. However, when different consumers read the same product review, their responses to it may vary. This study analyzes the characteristics of consumers who utilize product reviews for their purchases. Consumer characteristics are categorized into personal information, personality, purchasing tendency, and experience related to product reviews. These factors are examined to see if they have direct or indirect effects on a consumer's intention to use product reviews when making online purchases. We surveyed a total of 240 consumers who had experience using e-commerce and knew about online product reviews. Once the data was collected, path analysis was conducted using the statistics tool AMOS. The study results reveal that consumers who are female, extroverted, and have higher price sensitivity think that product reviews left by others are useful, and that this "perceived usefulness" has a positive effect on the intention to use product reviews for making online purchasing decisions. In addition, consumers who are agreeable to others, have high brand sensitivity, and who have left numerous reviews themselves demonstrated the tendency to trust reviews left by others more. Thus, we conclude that this "perceived reliability" makes it more likely that a consumer will use product reviews when making online purchasing decisions. Future research can be done to develop this study further by analyzing whether providing online product reviews corresponding to the personal characteristics of consumers enhances the effect of product reviews on online purchasing decisions.
Chanthavilay, Phetsavanh;Mayxay, Mayfong;Phongsavan, Keokedthong;Marsden, Donald E;White, Lisa J;Moore, Lynne;Reinharz, Daniel
Asian Pacific Journal of Cancer Prevention
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v.16
no.14
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pp.5889-5897
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2015
Background: The performance of combined testing visual inspection with acetic acid (VIA) and cervical cytology tests might differ from one setting to another. The average estimate of the testing accuracy across studies is informative, but no meta-analysis has been carried out to assess this combined method. Objective: The objective of this study was to estimate the average sensitivity and specificity of the combined VIA and cervical cytology tests for the detection of cervical precancerous lesions. Materials and Methods: We conducted a systematic review and a meta-analysis, according to the Cochrane Handbook for Systematic Review of Diagnostic Test Accuracy. We considered two cases. In the either-positive result case, a positive result implies positivity in at least one of the tests. A negative result implies negativity in both tests. In the both-positive case, a positive result implies having both tests positive. Eligible studies were identified using Pubmed, Embase, Website of Science, CINHAL and COCRANE databases. True positive, false positive, false negative and true negative values were extracted. Estimates of sensitivity and specificity, positive and negative likelihood (LR) and diagnostic odds ratios (DOR) were pooled using a hierarchical random effect model. Hierarchical summary receiver operating characteristics (HSROC) were generated and heterogeneity was verified through covariates potentially influencing the diagnostic odds ratio. Findings: Nine studies fulfilled inclusion criteria and were included in the analysis. Pooled estimates of the sensitivities of the combined tests in either-positive and both-positive cases were 0.87 (95% CI: 0.83-0.90) and 0.38 (95% CI: 0.29-0.48), respectively. Corresponding specificities were 0.79 (95% CI: 0.63-0.89) and 0.98 (95% CI: 0.96-0.99) respectively. The DORs of the combined tests in either-positive or both-positive result cases were 27.7 (95% CI: 12.5-61.5) and 52 (95% CI: 22.1-122.2), respectively. When including only articles without partial verification bias and also a high-grade cervical intraepithelial neoplasia as a threshold of the disease, DOR of combined test in both-positive result cases remained the highest. However, DORs decreased to 12.1 (95% CI: 6.05-24.1) and 13.8 (95% CI: 7.92-23.9) in studies without partial verification bias for the combined tests in the either-positive and both-positive result cases, respectively. The screener, the place of study and the size of the population significantly influenced the DOR of combined tests in the both-positive result case in restriction analyses that considered only articles with CIN2+ as disease threshold. Conclusions: The combined test in the either-positive result case has a high sensitivity, but a low specificity. These results suggest that the combined test should be considered in developing countries as a primary screening test if facilities exist to confirm, through colposcopy and biopsy, a positive result.
Kim, Jong-Sup;Park, Chin-Ho;Park, Hee-Dae;Lee, Chang-Kon;Lee, Hee-Keung;Chin, Byung-Rho
Maxillofacial Plastic and Reconstructive Surgery
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v.17
no.1
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pp.46-54
/
1995
Postoperative infection following orthognatic surgery is rare. When postoperative infections occur, the initial treatment consists of incision and drainage of the affected area, culturing to identify bacterial stains and verify antibiotic sensitivity, and the institution of the appropriate antibiotic regimen. Some plates and screws may eventually require removal, the initial therapy should be attempted to retain the plates and screws until adequete healing has taken place. In orthoganthic surgery, intra-operative complications as a lesion of inferior alveolar nerve, fracture of osteomised segments, incomplete sectioning, malposition of segments, haemorrhage may occur. The surgeon should be familiar with possible complications to be caused and how to manage them. Prevention of postoperative infection following the orthognathic surgery consists of minimal periosteal reflection, aseptic management of operation field, proper surgical technique, rigid fixation, prophylactic antibiotics.
Proceedings of the Korea Water Resources Association Conference
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2016.05a
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pp.49-49
/
2016
The impact of land cover changes on streamflow of the Akaki catchment will be assessed using Soil and Water Assessment Tool (SWAT) model. The study will analyze the historical land cover changes (1993 to 2016) that have taken place in the catchment and its effect on the streamflow of the study area. Arc GIS will be used to analysis the satellite images obtained from the United States Geological Survey (USGS). To investigate the impact of land cover change on streamflow the model set up will be done using readily available spatial and temporal data, and calibrated against measured discharge. Two third of the data will be used for model calibration (1993?2000) and the remaining one-third for model validation (2001?2004). Model performance will be evaluated by using Nash and Sutcliff efficiency (NS) and coefficient of determination (R2). The calibrated model will be used to assess two land cover change (2002 and 2016) scenarios and its likely impacts of land use changes on the runoff will be quantified. The evaluation of the model response to these changes on streamflow will be presented properly. The study will contribute a lot to understand land use and land cover change on streamflow. This enhances the ability of stakeholder to implement sound policies to minimize undesirable future impacts and management alternatives which have a significant role in future flood control of the study area.
Recently, much attentions are paid to the risk associated with increased uses of medium size radiation sources in medical and industrial fields. In this study, radiation risks to the worker and to the general public due to $^{99m}Tc$ generator were assessed for both normal and accident conditions. Based on the event tree technique, exposure scenarios for various situations were derived. Uncertainty analysis based on the Monte-Carlo technique was applied to the risk assessment for workers and members of the public in the vicinity of the work place. In addition, sensitivity analysis was performed on each of the five independent input parameters to identify importance of the parameters with respect to the resulting risk. Because the frequencies of normal tasks are fat higher than those of accidents, the total risk associated with normal tasks were higher than the accident risk. The annual dose due to normal tasks were $0.6mSv\;y^{-1}$ for workers and $0.014mSv\;y^{-1}$ for public, while in accident conditions $3.96mSv\;y^{-1}\;and\;0.0016mSv\;y^{-1}$, respectively. Uncertainty range of accident risk was higher by 10 times than that of normal risk. Sensitivity analysis revealed that source strength, working distance and working time were crucial factors affecting risk. This risk analysis methodology and its results will contribute to establishment of risk-informed regulation for medium and large radioactive sources.
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