• Title/Summary/Keyword: sensitive period

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The Characteristic of Fish Community Following the Restoration of Yangjae Stream (복원에 따른 양재천 어류 군집의 특성)

  • Lee, Hwang-Goo;Choi, Jun-Kil
    • Korean Journal of Environment and Ecology
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    • v.29 no.6
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    • pp.873-883
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    • 2015
  • From August 2012 to April 2013, the ichthyofauna and post-restoration properties of Yangjae stream were investigated. A total of 1,503 fish of 2 forms, 16 species and 5 families were studied during the survey period. A survey of the distribution of freshwater fish inhabiting Yangjae stream after restoration of the stream showed large populations of Zacco platypus and Rhynchocypris oxycephalus. From the frequency distribution of the total length for the Zacco platypus population inhabiting Yangjae stream, it was estimated that there are 4 distinct age groups, with an abundance of the 27-63 mm (Age $0^+$) category accounting for 51.3% of the population. The regression coefficient (b) for the length-weight relationship in Zacco platypus was 3.27, while the slope of the condition factor was positive, demonstrating that stable growth conditions are being maintained. Analysis of tolerance and trophic guilds showed a decrease in the numbers of sensitive species and insectivore species further downstream, and an increase in tolerant species and omnivore species. Principal component analysis using community indices and indices of biotic integrity (IBI) showed that there were differences according to the survey time: the first and second surveys showed major changes on certain single species populations while during the third survey, it was analyzed that the populations of various types of fish had established balance.

Impulse Trafficking in Neurons of the Mesencephalic Trigeminal Nucleus

  • Saito, Mitsuru;Kang, Young-Nam
    • International Journal of Oral Biology
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    • v.31 no.4
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    • pp.113-118
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    • 2006
  • In the primary sensory neuron of the mesencephalic trigeminal nucleus (MTN), the peripheral axon supplies a large number of annulospiral endings surrounding intrafusal fibers encapsulated in single muscle spindles while the central axon sends only a few number of synapses onto single ${\alpha}-motoneurons({\alpha}-MNs)$. Therefore, the ${\alpha}-{\gamma}$ linkage is thought to be very crucial in the jaw-closing movement. Spike activity in a ${\gamma}-motoneuron\;({\gamma}-MN)$ would induce a large number of impulses in single peripheral axons by activating many intrafusal fibers simultaneously, subsequently causing an activation of ${\alpha}-MNs$ in spite of the small number of synapses. Thus, the activity of ${\gamma}-MNs$ may be vital for modulation of jaw-closing movements. Independently of such a spindle activity modulated by ${\gamma}-MNs$, somatic depolarization in MTN neurons is known to trigger the oscillatory spike activity. Nevertheless, the trafficking of these spikes arising from the two distinct sources of MTN neurons is not well understood. In this short review, switching among multiple functional modes of MTN neurons is discussed. Subsequently, it will be discussed which mode can support the ${\alpha}-{\gamma}$ linkage. In our most recent study, simultaneous patch-clamp recordings from the soma and axon hillock revealed a spike-back-propagation from the spike-initiation site in the stem axon to the soma in response to a somatic current pulse. The persistent $Na^+$ current was found to be responsible for the spike-initiation in the stem axon, the activation threshold of which was lower than those of soma spikes. Somatic inputs or impulses arising from the sensory ending, whichever trigger spikes in the stem axon first, would be forwarded through the central axon to the target synapse. We also demonstrated that at hyperpolarized membrane potentials, 4-AP-sensitive $K^+$ current ($IK_{4-AP}$) exerts two opposing effects on spikes depending on their origins; the suppression of spike initiation by increasing the apparent electrotonic distance between the soma and the spike-initiation site, and the facilitation of axonal spike invasion at higher frequencies by decreasing the spike duration and the refractory period. Through this mechanism, the spindle activity caused by ${\gamma}-MNs$ would be safely forwarded to ${\alpha}-MNs$. Thus, soma spikes shaped differentially by this $IK_{4-AP}$ depending on their origins would reflect which one of the two inputs was forwarded to the target synapses.

Visibility of Internal Target Volume of Dynamic Tumors in Free-breathing Cone-beam Computed Tomography for Image Guided Radiation Therapy

  • Kauweloa, Kevin I.;Park, Justin C.;Sandhu, Ajay;Pawlicki, Todd;Song, Bongyong;Song, William Y.
    • Progress in Medical Physics
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    • v.24 no.4
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    • pp.220-229
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    • 2013
  • Respiratory-induced dynamic tumors render free-breathing cone-beam computed tomography (FBCBCT) images with motion artifacts complicating the task of quantifying the internal target volume (ITV). The purpose of this paper is to study the visibility of the revealed ITV when the imaging dose parameters, such as the kVp and mAs, are varied. The $Trilogy^{TM}$ linear accelerator with an On-Board Imaging ($OBI^{TM}$) system was used to acquire low-imaging-dose-mode (LIDM: 110 kVp, 20 mA, 20 ms/frame) and high-imaging-dose-mode (HIDM: 125 kVp, 80 mA, 25 ms/frame) FBCBCT images of a 3-cm diameter sphere (density=0.855 $g/cm^3$) moving in accordance to various sinusoidal breathing patterns, each with an unique inhalation-to-exhalation (I/E) ratio, amplitude, and period. In terms of image ITV contrast, there was a small overall average change of the ITV contrast when going from HIDM to LIDM of $6.5{\pm}5.1%$ for all breathing patterns. As for the ITV visible volume measurements, there was an insignificant difference between the ITV of both the LIDM- and HIDM-FBCBCT images with an average difference of $0.5{\pm}0.5%$, for all cases, despite the large difference in the imaging dose (approximately five-fold difference of ~0.8 and 4 cGy/scan). That indicates that the ITV visibility is not very sensitive to changes in imaging dose. However, both of the FBCBCT consistently underestimated the true ITV dimensions by up to 34.8% irrespective of the imaging dose mode due to significant motion artifacts, and thus, this imaging technique is not adequate to accurately visualize the ITV for image guidance. Due to the insignificant impact of imaging dose on ITV visibility, a plausible, alternative strategy would be to acquire more X-ray projections at the LIDM setting to allow 4DCBCT imaging to better define the ITV, and at the same time, maintain a reasonable imaging dose, i.e., comparable to a single HIDM-FBCBCT scan.

Characteristic of Fish Community in the Stream Flowing into the Han River in Seoul, Korea (서울시 한강으로 유입되는 하천의 어류 군집 특성)

  • Byeon, Hwa-Keun
    • Korean Journal of Environment and Ecology
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    • v.32 no.3
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    • pp.261-273
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    • 2018
  • This study investigated the characteristics of fish communities in the streams flowing into the Han river in Seoul in May 2016 through April 2017. The investigated streams were Ui stream, Danghyeon stream, Cheonggye stream, Yangjae stream, Mokgam stream, Dorim stream, and Hongje stream, which were restored to their natural form. We collected 41 species of 10 families using skimming nets and cast nets from 21 points during the investigation period. There were 7 Korean endemic species, or 17.1% in collected species, such as Acheilognathus yamatsutae, Acheilognathus gracilis, Scrcocheilichthys nigripinnis morii, Squalidus japonicus coreanus, Zacco koreanus, Coreoperca herzi, and Odontobutis interruta. There were 5 (12.2%) exotic species: Cyprinus carpio (fancy type), Carassius auratus (goldfish), Carassius cuvieri, Lepomis macrochirus, and Micropterus salmoides. The dominant species were Zacco platypus, Carassius auratus, Acheilognathus lanceolatus, Acheilognathus gracilis, and Oryzias sinensis. The Yangjae stream showed more stable fish community than other streams as it showed higher species diversity, and evenness and richness indices. Regarding the fish tolerance guild according to water quality, there were 3 (7.3%) sensitive species, 16 (39.0%) intermediate species, and 22 (56.7%) tolerant species. Twelve (29.3%) were insectivore species, 23 (56.1%) were omnivore species, and 6 (14.6%) were carnivore species, indicating the dominating presence of omnivore fish species.

Optimization of PRISM Parameters and Digital Elevation Model Resolution for Estimating the Spatial Distribution of Precipitation in South Korea (남한 강수량 분포 추정을 위한 PRISM 매개변수 및 수치표고모형 최적화)

  • Park, Jong-Chul;Jung, Il-Won;Chang, Hee-Jun;Kim, Man-Kyu
    • Journal of the Korean Association of Geographic Information Studies
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    • v.15 no.3
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    • pp.36-51
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    • 2012
  • The demand for a climatological dataset with a regular spaced grid is increasing in diverse fields such as ecological and hydrological modeling as well as regional climate impact studies. PRISM(Precipitation-Elevation Regressions on Independent Slopes Model) is a useful method to estimate high-altitude precipitation. However, it is not well discussed over the optimization of PRISM parameters and DEM(Digital Elevation Model) resolution in South Korea. This study developed the PRISM and then optimized parameters of the model and DEM resolution for producing a gridded annual average precipitation data of South Korea with 1km spatial resolution during the period 2000-2005. SCE-UA (Shuffled Complex Evolution-University of Arizona) method employed for the optimization. In addition, sensitivity analysis investigates the change in the model output with respect to the parameter and the DEM spatial resolution variations. The study result shows that maximum radius within which station search will be conducted is 67km. Minimum radius within which all stations are included is 31km. Minimum number of stations required for cell precipitation and elevation regression calculation is four. Optimizing DEM resolution is $1{\times}1km$. This study also shows that the PRISM output very sensitive to DEM spatial resolution variations. This study contributes to improving the accuracy of PRISM technique as it applies to South Korea.

Modelling the Effects of Temperature and Photoperiod on Phenology and Leaf Appearance in Chrysanthemum (온도와 일장에 따른 국화의 식물계절과 출엽 예측 모델 개발)

  • Seo, Beom-Seok;Pak, Ha-Seung;Lee, Kyu-Jong;Choi, Doug-Hwan;Lee, Byun-Woo
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.18 no.4
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    • pp.253-263
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    • 2016
  • Chrysanthemum production would benefit from crop growth simulations, which would support decision-making in crop management. Chrysanthemum is a typical short day plant of which floral initiation and development is sensitive to photoperiod. We developed a model to predict phenological development and leaf appearance of chrysanthemum (cv. Baekseon) using daylength (including civil twilight period), air temperature, and management options like light interruption and ethylene treatment as predictor variables. Chrysanthemum development stage (DVS) was divided into juvenile (DVS=1.0), juvenile to budding (DVS=1.33), and budding to flowering (DVS=2.0) phases for which different strategies and variables were used to predict the development toward the end of each phenophase. The juvenile phase was assumed to be completed at a certain leaf number which was estimated as 15.5 and increased by ethylene application to the mother plant before cutting and the transplanted plant after cutting. After juvenile phase, development rate (DVR) before budding and flowering were calculated from temperature and day length response functions, and budding and flowering were completed when the integrated DVR reached 1.33 and 2.0, respectively. In addition the model assumed that leaf appearance terminates just before budding. This model predicted budding date, flowering date, and leaf appearance with acceptable accuracy and precision not only for the calibration data set but also for the validation data set which are independent of the calibration data set.

A Nucleic Acid Amplification Tests for Reliable HCV RNA Detection Method for Plasma-Derived Products (핵산증폭시험을 이용한 혈장분획물질에서 HCV RNA 검출)

  • Hong, Seung-Hee
    • Korean Journal of Microbiology
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    • v.44 no.4
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    • pp.293-298
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    • 2008
  • HCV is transmitted via various plasma derived products. Current methods to detect hepatitis C virus (HCV) are based on its antibody detection in the donated blood and plasma. Viral contamination can potentially escape such detection during the window period of infection, when no antibody is present or the level of antibody is too low to detect. It is trying to application of nucleic acid amplification tests (NAT) for the direct detection of HCV. The objective of this study was to develop a reliable NAT for the HCV RNA detection from plasma-derived products. The most useful primers was selected for NAT among 5 sets of primers. We have also found that QIAamp viral RNA isolation kit was the most efficient for HCV RNA isolation. The highest sensitivity and specificity was appeared in $48^{\circ}C$ annealing temperature and 30 pmol of primers. With a spiking of HCV to albumin, immunoglobulins and coagulation factors, NAT can detect up to 100 IU/ml. Meanwhile, COBAS amplicor HCV 2.0 afforded a lower sensitivity in high concentrated intramuscular immunoglobulins to below 500 IU/ml. Our results suggested that NAT appears to be a highly sensitive and specific method for HCV RNA detection in plasma-derived products.

The Trend of Textile Design in the 1980s and Its Meaning in Historical Perspective (1980년대의 직물디자인 경향 및 그 사적 의미)

  • Park, Nam-Sung
    • Archives of design research
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    • v.17 no.4
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    • pp.211-222
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    • 2004
  • During the 1980s, Textile design achieved a remarkable growth in creating aesthetic effect and in establishing its standing by responding to demands of the time effectively and seeking changes proactively. This was a period when Textile design constructed its modern concept as it was attempting a qualitative improvement through advanced technology, high class, and differentiation. The advent of advanced materials through the development of textile engineering, employment of craft techniques to further cultural and artistic orientation, and restoration of decorativeness in pursuit of sensitivity, all these developments of the 1980s contributed to the rise of above characteristics. In this study, attempts are made to grasp the new trend of Textile design during the 1980s and to review diverse methods of aesthetic creation and plastic possibility which this trend presented for the Textile, and thus to recognize the role of Textile design and its importance in a new light. The new trend of Textile design during the 1980s can be summarized as follows: 1) An appreciation of the creative aspect of the Textile. As attempts are made to emphasize visual and sensitive aspects of the medium, Textile tended to become an object of art itself. 2) A new awareness of the representative and plastic capacity of the fiber material. As attempts are made to develope the creative potential of the Textile, representation of the material tended to become more diversified. 3) A recognition of the Textile as a proper means to deliver the spirit of the time. As the medium accommodates and fuses diverse cultures including traditional culture, more emphasis was place on cultural contents of the Textile. In the process of pursuing these changes, Textile design of the 1980s has also contributed to the creation of new values, laying the groundwork for its emergence as an advanced high value-added industry.

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The Application of Octa-Substituted Metallophthalocyanine Langmuir-Blodgett films for $NO_2$ Measurement (수정진동자를 이용한 프탈로시아닌 LB박막의 $NO_2$ 감지 특성)

  • Kwon, H.J.;Lee, Y.J.;Chang, Y.K.;Kim, J.D.
    • Journal of Sensor Science and Technology
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    • v.7 no.4
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    • pp.254-262
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    • 1998
  • Multilayer Langmuir-Blodgett (LB) films coated on quartz crystal microbalance (QCM) of octa-substituted metallophhtalocyanines ($MPc(OEH)_8$, M = Cu, Co, and Sn) and dihydrogen phthalocyanines ($H_2Pc(OEH)_8$) were used to quantify $NO_2$ concentrations. They were exposed to various concentrations of $NO_2$ in dry $N_2$. Among the four phthalocyanines we tested, the metal-free $H_2Pc(OEH)_8$ was observed to be most sensitive to $NO_2$. However, its LB film showed a partially irreversible behavior, that is part of the frequency change due to $NO_2$ adsorption could not be recovered even after purging with pure $N_2$ gas for an extended period. Examining the spectra of NMR and FTIR revealed fact that the irreversible portion of frequency change was due to ether groups in the linkage between side chains and the Pc unit. In order to remove the effect of such initial deactivation, on $NO_2$ quantification experiment, a freshly fabricated LB film was treated at a high concentration of $NO_2$ so that the ether sites were saturated. A pretreated LB film showed a reproducible performance for repeated uses. The $CuPc(OEH)_8$ LB film showed a satisfactory sensing performance down to as low as 4 ppm. For the $H_2Pc(OEH)_8$ LB film, the lower detection limit was found to be 35ppb of $NO_2$. In order to make the experimental condition more realistic, the carrier gas, dry nitrogen, was replaced by air. It was observed that the presence of oxygen, a weak electron acceptor, reduced the sensitivity and thus increased the sensing limit to hundreds of ppb. Results of experiments with moisture added showed that the interference of moisture was quite severe.

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Characteristics of Temporal Variation on Water Quality (T-P, T-N, CODMn, SS, BOD5) in the Jungrang Stream during Rainfall Event (강우 시 중랑천 유역의 수질(T-P, T-N, CODMn, SS, BOD5)변화 특성)

  • Jung, Jaehyung;Zhou, Xing;Lee, Taejin;Kwon, O-Yul
    • Journal of Korean Society of Environmental Engineers
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    • v.36 no.6
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    • pp.412-420
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    • 2014
  • Water quality variations were investigated at 4 locations of Jungrang river (upper, middle and lower basins) during a period of 3 rainfall events. During the rainfall, concentrations of $COD_{Mn}$, SS and $BOD_5$ significantly increased, while the concentration of T-N decreased and that of T-P remained relatively constant. This pattern became more apparent as the level of accumulative precipitation and rainfall intensity increased. Simple regression analysis showed that the accumulative precipitation was positively correlated with all water quality pollutants except for T-N. With increasing accumulative precipitation, the concentration of T-N decreased, while the others increased. $R^2$ of simple regressions of hourly average rainfall intensity and water quality pollutants, showed wider range of variation ranged from 0.483 to 0.992, which indicated a strong correlation. The stronger the hourly average rainfall intensity, the more T-N and T-P in the upper basin, more $COD_{Mn}$ in the middle and lower basins, more SS with gradual increase from upper to lower areas, and more $BOD_5$ with gradual decrease from upper to lower region. Simple regression showed that water quality pollution in the upper basin was more sensitive to an increase of rainfall discharge than that in the middle and lower areas.