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Differences in the Antibiotic Resistance Pattern of Staphylococcus aureus Isolated by Clinical Specimens in a University Hospital in South Korea (일개 대학병원의 임상 검체에서 분리한 포도알균 항생제 내성 경향 차이)

  • Hong, Seong-No;Kim, Joon;Sung, Hyun-Ho
    • Korean Journal of Clinical Laboratory Science
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    • v.50 no.2
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    • pp.85-92
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    • 2018
  • Information on the prevalence of S. aureus and the current antimicrobial resistance profile is necessary in selecting the appropriate treatment of S. aureus infections in any part of the world. This study examined the frequency and antibiotic resistance list of S. aureus isolates obtained from clinical specimens at one hospital in Korea. A total of 1,746 gram positive cocci collected were identified as S. aureus. S. aureus isolates were obtained from different samples including sputum (N=565; 32.4%), endotracheal aspirate (358; 20.5%), wounds (329; 18.8%), blood (137; 7.8%), urine (67; 3.8%), and pus (59; 3.4%). All 1,545 S. aureus (100%) strains screened from sputum (565; 36.6%), endotracheal aspirate (388; 25.1%), wounds (329; 21.3%), blood (137; 8.9%), urine (67; 4.3%), and pus (59; 3.8%) were sensitive to glycopeptide (vancomycin, teicoplanin), oxazolidinone (linezolid) and stretogramin (quinupristin/dalfopristin). The prevalence of resistant S. aureus was significantly (P<0.01) lower in urine, blood, pus, wounds, and sputum than in endotracheal aspirates. As a result, there was a significant difference in the antibiotic resistance of S. aureus according to the clinical specimens.

Inferring Regional Scale Surface Heat Flux around FK KoFlux Site: From One Point Tower Measurement to MM5 Mesoscale Model (FK KoFlux 관측지에서의 지역 규모 열 플럭스의 추정 : 타워 관측에서 MM5 중규모 모형까지)

  • Jinkyu Hong;Hee Choon Lee;Joon Kim;Baekjo Kim;Chonho Cho;Seongju Lee
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.5 no.2
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    • pp.138-149
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    • 2003
  • Korean regional network of tower flux sites, KoFlux, has been initiated to better understand $CO_2$, water and energy exchange between ecosystems and the atmosphere, and to contribute to regional, continental, and global observation networks such as FLUXNET and CEOP. Due to heterogeneous surface characteristics, most of KoFlux towers are located in non-ideal sites. In order to quantify carbon and energy exchange and to scale them up from plot scales to a region scale, applications of various methods combining measurement and modeling are needed. In an attempt to infer regional-scale flux, four methods (i.e., tower flux, convective boundary layer (CBL) budget method, MM5 mesoscale model, and NCAR/NCEP reanalysis data) were employed to estimate sensible heat flux representing different surface areas. Our preliminary results showed that (1) sensible heat flux from the tower in Haenam farmland revealed heterogeneous surface characteristics of the site; (2) sensible heat flux from CBL method was sensitive to the estimation of advection; and (3) MM5 mesoscale model produced regional fluxes that were comparable to tower fluxes. In view of the spatial heterogeneity of the site and inherent differences in spatial scale between the methods, however, the spatial representativeness of tower flux need to be quantified based on footprint climatology, geographic information system, and the patch scale analysis of satellite images of the study site.

Cure Monitoring of Am Epoxy-Anhydride System by Means of Fluorescence Spectroscopy (형광분석기를 이용한 에폭시-산무수물계의 경화 모니터링)

  • 조동환;김득수;이종근
    • Polymer(Korea)
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    • v.25 no.2
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    • pp.199-207
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    • 2001
  • In the present study the cure behavior of diglycidyl ether of bisphenol-A(DGEBA) using an anhydride-based hardener in the presence of N,N-dimethyl benzyl amine (BDMA) or 1-cyanoethyl-2-ethyl-4-methyl imidazole (2E4MZ-CN) as an accelerator has been monitored and interpreted from the viewpoint of photophysical properties by means of fluorescence spectroscopy. To do this, 1,3-bis-(1-pyrene)propane (BPP) was well incorporated in the epoxy resin system by mechanical blending. The BPP probe, which is very sensitive to conformational change of the molecule influenced by the surrounding medium, successfully formed intramolecular excimer fluorescence. It is susceptible to the micro-viscosity or local viscosity and molecular mobility according to the epoxy cure. The cure behavior was explained with monomer fluorescence intensity ($I_{M}$ ), excimer fluorescence intensity ($I_{E}$ ) and $I_{M}$ /$I_{E}$ ratio as a function of cure time, cure temperature and accelerator. The present work agreed with the previous report on the cure behavior of an epoxy-anhydride system studied using DSC or torsion pendulum method. This study also suggests that the use of fluorescence technique may provide information on cure behavior of a thermosetting resin in a low temperature region, which has not been well interpreted by other analytical methods.

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A Preliminary Study on a Restoration of Habitats for Nannophya pygmaea Rambur (Odonata: Libellulidae) (꼬마잠자리(Nannophya pygmaea Rambur: Libellulidae, Odonata) 서식처 복원을 위한 기초연구)

  • Lee, Eun-Heui;Jang, Ha-Kyung;Park, Min-Young;Yoon, Ji-Hyun;Kim, Jae-Geun;Bae, Yeon-Jae
    • Korean Journal of Environment and Ecology
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    • v.22 no.1
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    • pp.35-42
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    • 2008
  • This study was conducted to provide basic information that can be used to restore habitats of Nannophya pygmaea. Nannophya pygmaea is an endangered species of wildlife fauna in Korea and its habitats are distributed very scarcely in Korea. Ten wetland sites throughout Korea, where N. pygmaea inhabited (2 sites in Incheon Muui-do, 1 site in Gokseong Singi-ri, 4 sites in Gokseong Wolbong-ri, and 3 sites in Mungyeong Yulsu-ri) were investigated from June 2006 to August 2007. Investigation was made on landscape properties, habitat sizes, vegetation types, water environments, and water sources. N. pygmaea was generally found in the abandoned paddy fields surrounded by mountains. The habitats ranged from $113.4m^2$ to $1,153.1m^2$ in area, and were mostly dominated by Juncus effusus and Persicaria thunbergii. The water level was $2.6\sim7.3cm$, and the water temperature ranged from $16^{\circ}C$ to $27.8^{\circ}C$. The elevation of the habitats ranged from 139 to 243 m above sea level, which was mostly lower than that of other high mountain wetland habitats. In conclusion, the habitats of N. pygmaea can be restored at wetlands, which have similar condition with field habitat such as abandoned paddy fields in the beginning stage of oligotrophy. Because N. pygmaea is sensitive to microtopography and other surrounding environments, the approach to restore the habitats for N. pygmaea should consider those microhabitat conditions shown in this study.

Effect of γ-Ray Mutagen Treatment on Botanical Characteristics of Local Small Grain Soybean (Glycine max. L) Lines (돌연변이원(突然變異源) γ-선(線) 처리(處理)가 재래종(在來種) 소립(小粒)콩의 식물학적(植物學的) 특성(特性)에 미치는 영향(影響))

  • Lee, Hee Bong;Kim, Gi Hoon;Kim, Chol Min;Ju, Jung Il
    • Korean Journal of Agricultural Science
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    • v.25 no.2
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    • pp.149-153
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    • 1998
  • This experiment was carried out to obtain a basic information for new variety development. The local soybean (Glycine max. L) lines used were endowed from Chungnam Agricultural Research and Extension Services. These lines were planted at upland farm of Chungnam Nat'l Univ., College of Agri. after treatment with mutagen $\gamma$-ray. All characteristics measured were decreased due to the $\gamma$-ray treatment than check except the branches of main stem of the Hannam and plant height of the Sobak. Especially the Sobak and the Eunha among these lines were shown very sensitivly than others treated with $\gamma$-ray of 15Krad. Of characteristics surveyed the nodes per plant was very sensitive to $\gamma$-ray, while the grain weight per plant, the pods per plant and the branches per plant were gradually decreased to further radioactivity about $\gamma$-ray treatment. In the Pungsan and the Sobak lines there were not shown significant between major characteristics at treatments including check. Other lines were also not shown positive correlation among characteristics except between stem diameter and branches(0.64*), grain weight and plant height(0.77**) at check of the Eunha, between stem nodes and stem diameter(0.65*) at check of the Kwangan and between number of pods and stem diameter(0.70*) at check of the Danyeop. From result this experiment, some of lines used were to be appeared characters of interest, for example, such as the short stem and the early flowering. Therefore these lines were needed more advanced generations for stability and performance.

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Facilitation of AMPA receptor-mediated steady-state current by extrasynaptic NMDA receptors in supraoptic magnocellular neurosecretory cells

  • Pai, Yoon Hyoung;Lim, Chae Seong;Park, Kyung-Ah;Cho, Hyun Sil;Lee, Gyu-Seung;Shin, Yong Sup;Kim, Hyun-Woo;Jeon, Byeong Hwa;Yoon, Seok Hwa;Park, Jin Bong
    • The Korean Journal of Physiology and Pharmacology
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    • v.20 no.4
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    • pp.425-432
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    • 2016
  • In addition to classical synaptic transmission, information is transmitted between cells via the activation of extrasynaptic receptors that generate persistent tonic current in the brain. While growing evidence supports the presence of tonic NMDA current ($I_{NMDA}$) generated by extrasynaptic NMDA receptors (eNMDARs), the functional significance of tonic $I_{NMDA}$ in various brain regions remains poorly understood. Here, we demonstrate that activation of eNMDARs that generate INMDA facilitates the ${\alpha}$-amino-3-hydroxy-5-methylisoxazole-4-proprionate receptor (AMPAR)-mediated steady-state current in supraoptic nucleus (SON) magnocellular neurosecretory cells (MNCs). In $low-Mg^{2+}$ artificial cerebrospinal fluid (aCSF), glutamate induced an inward shift in $I_{holding}$ ($I_{GLU}$) at a holding potential ($V_{holding}$) of -70 mV which was partly blocked by an AMPAR antagonist, NBQX. NBQX-sensitive $I_{GLU}$ was observed even in normal aCSF at $V_{holding}$ of -40 mV or -20 mV. $I_{GLU}$ was completely abolished by pretreatment with an NMDAR blocker, AP5, under all tested conditions. AMPA induced a reproducible inward shift in $I_{holding}$ ($I_{AMPA}$) in SON MNCs. Pretreatment with AP5 attenuated $I_{AMPA}$ amplitudes to ~60% of the control levels in $low-Mg^{2+}$ aCSF, but not in normal aCSF at $V_{holding}$ of -70 mV. $I_{AMPA}$ attenuation by AP5 was also prominent in normal aCSF at depolarized holding potentials. Memantine, an eNMDAR blocker, mimicked the AP5-induced $I_{AMPA}$ attenuation in SON MNCs. Finally, chronic dehydration did not affect $I_{AMPA}$ attenuation by AP5 in the neurons. These results suggest that tonic $I_{NMDA}$, mediated by eNMDAR, facilitates AMPAR function, changing the postsynaptic response to its agonists in normal and osmotically challenged SON MNCs.

Delineation of Provenance Regions of Forests Based on Climate Factors in Korea (기상인자(氣象因子)에 의한 우리 나라 산림(山林)의 산지구분(産地區分))

  • Choi, Wan Yong;Tak, Woo Sik;Yim, Kyong Bin;Jang, Suk Seong
    • Journal of Korean Society of Forest Science
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    • v.88 no.3
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    • pp.379-388
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    • 1999
  • As a first step for delineating the provenance regions of the forest trees in Korea, horizontal zones have been deduced primarily from the various climatic factors such as annual mean temperature, extremely low temperature, relative humidity, annual gum of possible growing days, duration of sunshine and dry index. The basic concept to the delineation of the provenance regions was based on the ecological regions, which was likely to be more practical than that on the basis of the typical provenance regions at the species level. Primary classification of the regions has been based on the forest zones(sub-tropical, warm-temperate, mid-temperate and cool-temperate) as a broad geographic region. Further classification has been carried out using cluster analyses among the basic regions within forest zone. On the basis of clustering, a total of 19 regions including 3 from sub-tropical, 6 from warm-temperate, 8 from mid-temperate and 2 from cool-temperate was horizontally delineated. Of the mean values of 6 climate factors at the broad geographic region level, three factors such as annual mean temperature, extremely low temperature, annual growing days showed directional tendencies from subtropical to cool-temperate, while the others didn't. The values of relative humidity, duration of sunshine and dry index varied among the provenance regions within forest zone. These three factors might he more sensitive by the micro-environment condition than by the macro-environment condition. Present study aimed to delineate the primary provenance regions for tentative application to forest practices. These will be stepwise revised through the supplement using accumulated information regard to genecological data.

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A Study on the Dyadic Sorting method for the Regularization in DT-MRI (Dyadic Sorting 방법을 이용한 DT-MRI Regularization에 관한 연구)

  • Kim, Tae-Hwan;Woo, Jong-Hyung;Lee, Hoon;Kim, Dong-Youn
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.47 no.4
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    • pp.30-39
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    • 2010
  • Since Diffusion tensor from Diffusion Tensor Magnetic Resonance Imaging(DT-MRI) is so sensitive to noise, the principle eigenvector(PEV) calculated from Diffusion tensor could be erroneous. Tractography obtained from PEV could be deviated from the real fiber tract. Therefore regularization process is needed to eliminate noise. In this paper, to reduce noise in DT-MRI measurements, the Dyadic Sorting(DS) method as regularization of the eigenvalue and the eigenvector is applied in the tractography. To resort the eigenvalues and the eignevectors, the DS method uses the intervoxel overlap function which can measure the overlap between eigenvalue-eigenvector pairs in the $3\times3$ pixel. In this paper, we applied the DS method to the three-dimensional volume. We discuss the error analysis and numerical study to the synthetic and the experimental data. As a result, we have shown that the DS method is more efficient than the median filtering methods as much as 79.97%~83.64%, 85.62%~87.76% in AAE, AFA respectively for the corticospinal tract of the experimental data.

A Method of Integrating Scan Data for 3D Face Modeling (3차원 얼굴 모델링을 위한 스캔 데이터의 통합 방법)

  • Yoon, Jin-Sung;Kim, Gye-Young;Choi, Hyung-Il
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.46 no.6
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    • pp.43-57
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    • 2009
  • Integrating 3D data acquired in multiple views is one of the most important techniques in 3D modeling. However, the existing integration methods are sensitive to registration errors and surface scanning noise. In this paper, we propose a integration algorithm using the local surface topology. We first find all boundary vertex pairs satisfying a prescribed geometric condition in the areas between neighboring surfaces, and then separates areas to several regions by using boundary vertex pairs. We next compute best fitting planes suitable to each regions through PCA(Principal Component Analysis). They are used to produce triangles that be inserted into empty areas between neighboring surfaces. Since each regions between neighboring surfaces can be integrated by using local surface topology, a proposed method is robust to registration errors and surface scanning noise. We also propose a method integrating of textures by using parameterization technique. We first transforms integrated surface into initial viewpoints of each surfaces. We then project each textures to transformed integrated surface. They will be then assigned into parameter domain for integrated surface and be integrated according to the seaming lines for surfaces. Experimental results show that the proposed method is efficient to face modeling.

A Real-Time Data Transfer Mechanism Considering Link Error Rates in Wireless Sensor Networks (무선 센서 네트워크에서 링크 에러율을 고려한 실시간 데이터 전달 기법)

  • Choi, Jae-Won;Lee, Kwang-Hui
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.44 no.1
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    • pp.146-154
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    • 2007
  • In this paper, we have presented a real-time transfer mechanism for the delay-sensitive data in WSNs (Wireless Sensor Networks). The existing methods for real-time data transfer select a path whose latency is shortest or the number of hops is least. Although the approaches of these methods are acceptable, they do not always work as efficiently as they can because they had no consideration for the link error rates. In the case of transmission failures on links, they can not guarantee the end-to-end real-time transfer due to retransmissions. Therefore, we have proposed an algorithm to select a real-time transfer path in consideration of the link error rates. Our mechanism estimates the 1-hop delay based on the link error rate between two neighboring nodes, which in turn enables the calculation of the expected end-to-end delay. A source node comes to choose a path with the shortest end-to-end delay as a real-time route, and sends data along the path chosen. We performed various experiments changing the link error rates and discovered that this proposed mechanism improves the speed of event-to-sink data transfer and reduces delay jitter. We also found that this mechanism prevents additional energy consumption and prolongs network lifetime, resulting from the elative reduction of transmission failures and retransmissions.