• Molecules and Cells
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• v.40 no.2
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• pp.117-122
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• 2017

Despite the fact that porcine embryonic stem cells (ESCs) are a practical study tool, in vitro long-term maintenance of these cells is difficult in a two-dimensional (2D) microenvironment using cellular niche or extracellular matrix proteins. However, a three-dimensional (3D) microenvironment, similar to that enclosing the inner cell mass of the blastocyst, may improve in vitro maintenance of self-renewal. Accordingly, as a first step toward constructing a 3D microenvironment optimized to maintain porcine ESC self-renewal, we investigated different culture dimensions for porcine ICM-derived cells to enhance the maintenance of self-renewal. Porcine ICM-derived cells were cultured in agarose-based 3D hydrogel with self-renewal-friendly mechanics and in 2D culture plates with or without feeder cells. Subsequently, the effects of the 3D microenvironment on maintenance of self-renewal were identified by analyzing colony formation and morphology, alkaline phosphatase (AP) activity, and transcriptional and translational regulation of self-renewal-related genes. The 3D microenvironment using a 1.5% (w/v) agarose-based 3D hydrogel resulted in significantly more colonies with stereoscopic morphology, significantly improved AP activity, and increased protein expression of self-renewal-related genes compared to those in the 2D microenvironment. These results demonstrate that self-renewal of porcine ICM-derived cells can be maintained more effectively in a 3D microenvironment than in a 2D microenvironment. These results will help develop novel culture systems for ICM-derived cells derived from diverse species, which will contribute to stimulating basic and applicable studies related to ESCs.

• Development and Reproduction
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• v.21 no.1
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• pp.93-100
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• 2017

Obesity is characterized by a state of chronic low-grade inflammation and insulin resistance, which are aggravated by the interaction between hypertrophic adipocytes and macrophages. In this study, we investigated the effects of tangeretin on inflammatory changes and glucose uptake in a coculture of hypertrophic adipocytes and macrophages. Tangeretin decreased nitric oxide production and the expression of interleukin (IL)-6, $IL-1{\beta}$, tumor necrosis $factor-{\alpha}$, inducible nitric oxide synthase, and cyclooxygenase-2 in a coculture of 3T3-L1 adipocytes and RAW 264.7 cells. Tangeretin also increased glucose uptake in the coculture system, but did not affect the phosphorylation of insulin receptor substrate (IRS) and Akt. These results suggest that tangeretin improves insulin resistance by attenuating obesity-induced inflammation in adipose tissue.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.05a
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• pp.38-40
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• 2021

Medical domain has a massive number of data records without the response value. Self-supervised learning is a suitable method for medical data since it learns pretext-task and supervision, which the model can understand the semantic representation of data without response values. However, since self-supervised learning performance depends on the expression learned by the pretext-task, it is necessary to define an appropriate Pretext-task with data feature consideration. In this paper, to actively exploit the unlabeled medical data into artificial intelligence research, experimentally find pretext-tasks that suitable for the medical data and analyze the result. We use the x-ray image dataset which is effectively utilizable for the medical domain.

• Journal of Families and Better Life
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• v.20 no.2
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• pp.123-134
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• 2002

This study examined the effects of children′s personality traits on children′s emotional intelligence. The Subjects were 1060 5th graders of elementary schools located in four cities of Seoul, Suwon, Daejeon, and Daegu, Korea. The results indicated that girls in general showed more of the positive personality traits and higher emotional intelligence(EI) than boys did. Reflectiveness and sociability among seven personality factors had positive effects on all of the four EI factors. Responsibility factor of personality positively affected "self-regulation and emotion utilization" of both boys and girls, while activity factor had a positive effect on "other-regulation and self-expression". Stability had a possitive effect on "self-regulation and emotion utilization" among girls, whereas superiority had a negative effect on "empathy" among boys.

• Structural Engineering and Mechanics
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• v.12 no.1
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• pp.85-100
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• 2001

In this paper, an analytical procedure for solving several static and dynamic problems of non-uniform beams is proposed. It is shown that the governing differential equations for several stability, free vibration and static problems of non-uniform beams can be written in the from of a unified self-conjugate differential equation of the second-order. There are two functions in the unified equation, unlike most previous researches dealing with this problem, one of the functions is selected as an arbitrary expression in this paper, while the other one is expressed as a functional relation with the arbitrary function. Using appropriate functional transformation, the self-conjugate equation is reduced to Bessel's equation or to other solvable ordinary differential equations for several cases that are important in engineering practice. Thus, classes of exact solutions of the self-conjugate equation for several static and dynamic problems are derived. Numerical examples demonstrate that the results calculated by the proposed method and solutions are in good agreement with the corresponding experimental data, and the proposed procedure is a simple, efficient and exact method.

• Fashion & Textile Research Journal
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• v.8 no.2
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• pp.177-182
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• 2006

The purpose of this study is to examine the effect of media on plastic surgery experiment. Firstly this study try to find the relationship between exposure to media and other intervening factors(e.g., body image, self-esteem, fashion attitude). The data collected for this study was gathered through questionnaire survey with 443 female students in Seoul. The results are as follows: Using ANOVA, we found that those prefer the magazine over TV or Internet had positive body image, higher self-esteem, and positive fashion attitude(e.g., personality/self-expression, fashion leadership, sexual attraction). Using regression analysis, we found that the we found that the factors influence plastic surgery behavior are the exposure to magazine and the factors influence plastic surgery planning are the clothing attitude (especially fashion leading power, sexual attraction).

• Journal of the Korean Society of Clothing and Textiles
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• v.20 no.5
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• pp.738-752
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• 1996

The purposes of this study were 1) to test the interactive effects of usage-situation (wedding receptions, home, and vacation) and personal characteristics (age, income, education, job or self-monitoring) on clothing benefits sought and 2) to identify brand type preference of consumer groups segmented by age, income, education, job or self-monitoring within a situation. The data were collected via a questionnaire from 601 housewives of ages 20's∼ 50's living in Seoul, Korea. The data were analyzed by factor analysis, repeated measure two-way ANOVA and Chi-square test. The results of this study were as follows. First, by repeated measure tow-way ANOVA, there were significant interactions of age and situation, and interactions of education and situation on Youth/Fashion benefits and Brand-value benefits. And interactive effects of education and situation on Self-expression benefits and Economic-value benefits were significant by repeated measure two-way A NOVA. Second, based on x2-test, brand type preference was significant difference between consumer groups segmented by age, education and job within a situation. And preferences of brand type were different among usage situations.

• Korean Journal of Human Ecology
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• v.12 no.2
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• pp.237-251
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• 2003

The purpose of this study was to investigate the relationship between psychological characteristics(needs, self-consciousness, self-esteem), attitude toward appearance and clothing attitude of high school students. Method of posing a questionnaire was adopted to obtain stochastic data required for pertinent analysis. This is the investigation of which 489(male 236, female 253) high school students located in Chungnam and Jeollabukdo province. In this statistical analysis, SPSS 10.0 for Windows Program was utilized to calculate percentage, mean and standard deviation Also, these materials were verified by factor analysis, t-test, multiple regression analysis. The results of this research were as follows: The results of analysing the factors to the response attitude toward appearance emerged three factors(conformity value needs toward appearance). Gender had the significant effects on the psychological characteristics, attitude toward appearance and clothing attitude of high school students. Psychological characteristics, attitude toward appearance of high school students had an effects on clothing attitude, i.e. gender attractiveness, fashion pursuit, self-expression aesthetic, and modesty.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2002.03a
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• pp.219-227
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• 2002

In this paper, we designed neural network predictive PID controller to control sway happened in transfer of trolley for automatic travel control system. We include dynamic character of nonlinear system, and mathematical expression veny simple used neural network. When various establishment location and surrounding disturbance were approved based on mathematical modelling of crane, controller designed to become effective control location error and vibration angle of two control variables that simultaneously can predictive control. Neural network predictive PID controller produced parameter of PID controller using neural network self-tuner. Neural network self-tuner's input used crane's output and neural network predictive output. Neural network self-tuner using error back propagation algorithm. We analyzed control performance comparison through computer simulation when applied disturbance about sway of location and angle in transfer of crane. The results show that the proposed neural network predictive PID controller has better performances than general PID controller, neural network PID controller.

• Korean Journal of Child Studies
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• v.25 no.6
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• pp.299-319
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• 2004

This study designed, implemented, and evaluated a Biblio-Counseling program for elementary school children. Procedures included 20 60-minute sessions by counselor, 18 20-minute sessions in class by teacher, and 5 20-minute sessions at home by parents. The program was administered to 23 third grade elementary school children. Data were analyzed by frequency, mean, and paired t-test, using SPSS program packages. Results showed significant before and after differences in the degree of self-esteem. Besides, the children reported increased positive expression in class and decreased peer neglect and rejection at school. Children, parents and teacher expressed high satisfaction with the program. These results suggest that the multi-faceted approach as designed and implemented in this study is effective in promoting self-esteem, interpersonal growth, and relationship between child and parents.