• 대한한방내과학회지
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• 제19권1호
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• pp.221-246
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• 1998

The aim of this experimental study was to evaluate the anti-tumor effects of Chungsimbohyeltang through investigation about viability of tumor cell by MTT assay, survival period of mice transplanted with L-1210 cells, growth inhibition on the tumor cell, body weight variation in mice transplanted with sarcoma-180 cells and its immunomodulatory effects through the investigation on delayed type hyper-sensitivity, the hemagglutinin and hemolysin titers for humoral immune response, the appearance of rosette forming cells for cell-mediated immune response, the natural killer cell activity, the transformation of lymphocyte, the productivity of Interleukin-2 and phagocytic index K was performed in immune-depressed ICR mice induced by methotrexate treatments. The results were as follows ; 1. $IC_{50}$ of Chungsimbohyeltang treated group was 5.85mg/ml in SNU-C4 cell, 1.38mg/ml in SNU-396 cell, 0.21mg/ml in SNU-1 cell, so it had low anti-tumor activity. 2. The both groups of Chungsimbohyeltang extract 10mg/kg and Chungsimbohyeltang extract 20mg/kg had no toxicity and the group of Chungsimbohyeltang 20mg/kg which was shown 120% in ILS had the effect of life prolongation in mice transplanted with L-1210 cells. 3. In the growth inhibition on the tumor cells, only the group of Chungsimbohyeltang extract 20mg/kg was noted and in the weight variation in mice transplanted with sarcoma-180 cells, both groups of Chungsimbohyeltang extract had a significant effect. 4. In the delayed type hypersensitivity and appearance of rosette forming cells, both groups of Chungsimbohyeltang extract didn't have any significant effect. 5. The hemagglutinin titers was slightly increased with no significance, and the hemolysin titers was significantly increased in the only group of Chungsimbohyeltang extract 20mg/kg. 6. The natural killer cell activity of the Chungsimbohyeltang extract groups was significantly increased in the ratio of 100:1 of effector and target cells, but it was not significantly increased in the ratio of 50:1, 10:1. 7. The transformation of lymphocyte and the productivity of Interleukin-2 were increased significantly and in dose-dependent manner in both group of Chungsimbohyeltang extract. 8. The phagocytic effect of macropage was significantly increased in both groups of Chungsimbohyeltang extract. Considering the results above, we could conclude that Chungsimbohyeltang have an indirect anti-tumor effect through the modulation of immunme response, although it had not toxicity on the tumor cell it self.

• Journal of Acupuncture Research
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• 제20권3호
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• pp.24-33
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• 2003

Background : Sequelae symptoms of peripheral facial palsy include not only partial recovery of the paretic muscles but contracture, spasm, synkinesis and atrophy which cause significant functional, esthetic, and psychosocial disturbances to the lives of patients. Objective : This study is to investigate the prevalence, time of onset, patient's self assessment on the degree of understanding of the sequelae and the association of the degree of palsy with the appearance of sequelae. Methods : 106 patients with peripheral facial palsy were sequentially interviewed and examined. Results : 29 patients(27.4%) of 106 patients showed sequelae symptoms, of whom 19 patients(65.5%) showed sequelae symptoms during 4 to 6 months after the onset of palsy. The degree of understanding on the sequelae at the time of interview showed improvement compared to that at the time of first consultation to any physician but not to reach an sufficient understanding. No relation between the degree of palsy and the appearance of sequelae was observed.

• 한국작물학회지
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• 제27권4호
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• pp.385-397
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• 1982

The climatic impacts have been the environmental constraints with soil characteristics to achieve self sufficiency of food production in Korea. In this paper, the distribution and appearance of impacts and the changes in climatological status due to recent trend of early transplanting of rice are widely discussed to derive some countermeasures against the impacts, being focussed on cultural A long term analysis of the climatic impact appearances of the last 74 years showed that drought, strong wind, flood, cold spell and frost were the major impacts. Before 1970's, the drought damage was the greatest among the climatic impacts; however, the expansion and improvement of irrigation and drainage system markedly decreased the damage of drought and heavy rain. The appearance of cold damage became more frequent than before due to introduction of early transplanting for more thermophilic new varieties. Tongillines which were from Indica and Japonica crosses throw more attention to cold damage for high yields to secure high temperature in heading and ripening stages and lead weakness to cold and drought damage in early growth stage after transplanting. The plants became subject to heavy rain in ripening stage also. For the countermeasures against cold damage, the rational distribution of adequate varieties according to the regional climatic conditions and planting schedule should be imposed on the cultivation. A detoured water way to increase water temperature might be suggestable in the early growth stage. Heavy application of phosphate to boost rooting and tillering also would be a nutritional control method. In the heading and ripening stages, foliar application of phosphate and additional fertilization of silicate might be considerable way of nutritional control. Since the amount of solar radiation and air temperature in dry years were high, healthy plants for high yield could be obtained; therefere, the expansion of irrigation system and development of subsurface water should be performed as one of the national development projects. To minimize the damage of strong wind and rainfall, the rational distribution of varieties with different growing periods in the area where the damage occurred habitualy should be considered with installation of wind breaks. Not only vertical windbreaks but also a horizontal wind break using a net might be a possible way to decrease the white heads in rice field by dry wind. Finally, to establish the integrated countermeasures against the climatic impacts, the detailed interpretation on the regional climatic conditions should be conducted to understand distribution and frequency of the impacts. The expansion of observation net work for agricultural meteorology and development of analysis techniques for meteorological data must be conducted in future together with the development of the new cultural techniques.

• 한국과학예술포럼
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• 제31권
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• pp.355-365
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• 2017

미래 한국의 인구 구성은 저 출산과 의료기술의 비약적 발전에 힘입어 고령자가 2060년에는 세계 2위 수준까지 예상되고 있다. 고령자를 위한 사회의 부담은 지속적으로 증가될 것으로 예상되고 있다. 고령자가 되면서 제일 먼저 나타나는 현상은 신체적인 변화이다. 기억력이 낮아지고 인지능력이 저하되는 현상이 생기면서 그들의 활동이 제한되고 경제적인 생산능력이 급격히 줄어들게 된다. 자급자족이 힘든 상황이 되면서 경제적이고 사회적인 측면의 도움을 필요하게 되었다. 그들에게 도움을 줄 수 있는 제품이 연구되고 개발되어 져야하는 시기가 도래되었다. 고령자들에게 흔히 나타나는 인지능력저하 단계인 경도인지장애(MIS)단계가 있다. 경도인지장애인들은 약물적 치료방법과 비약물적 치료 방법을 병행하는 것이 효과적이다. 비약물적 치료방법 중 음악에 대한효과가 입증되어 있다. 본 논문은 음악치료기법을 활용한 보조기구를 개발함에 있어 디자인적인 관점에서 디지털 융복합의 연구가 필요하다. 본 연구를 위해서 경도인지장애자를 대상으로 외형에 대한 선호를 알아보았다. 2번에 걸쳐 설문조사가 이루어졌다. 연구의 결과 경도인지장애자를 위한 홈케어 제품디자인은 기존의 게임기나 셋탑박스의 정형적이고 박스형태가 아닌 사용자의 상황과 특수성을 고려한 형태가 요구되고 있다. 기억력, 인지능력이 떨어지는 신체적인 변화와 주변 사람이나 환경이 변화되는 정신적인 변화에 맞는 제품이 개발되도록 디자인이 요구되고 있다는 결과이다.

• 대한간호학회지
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• 제20권2호
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• pp.227-248
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• 1990

The study was conceived in relation to a concern over the growing gap between the needs of chronic patients and the availability of care from the current health care system in Korea. Patients with agonizing chronic pain, discomfort, despair and disability are left with helplessly unprepared families with little help from the acute care oriented health care system after discharge from hospital. There is a great need for the development of an alternative means of quality care that is economically feasible and culturally adaptible to our society. Thus, the study was designed to demonstrate the effectiveness of home heath care as an alternative to bridge the existing gap between the patients' needs and the current practice of health care. The study specifically purports to test the effects of home care on health expenditure, readmission, job retention, compliance to health care regime, general conditions, complications, and self-care knowledge and practices. The study was guided by the operations research method advocated by the Primary Health Care Operations Research Institute(PRICOR) which constitutes 3 stages of research : namely, problem analysis solution development, and solution validation. The first step in the operations research was field preparation to develop the necessary consensus and cooperation. This was done through the formation of a consulting body at the hospital and a steering committee among the researchers. For the stage of problem analysis, the Annual Report of Seoul National University Hospital and the patients records for last 5 years were reviewed and selective patient interviews were conducted to find out the magnitude of chronic health problems and areas of unmect health care needs to finally decide on the kinds of health problems to study. On the basis of problem analysis, the solution development stage was devoted to home care program development asa solution alternative. Assessment tools, teaching guidelines and care protocols were developed and tested for their validity. The final stage was the stage of experimentation and evaluation. Patients with liver diseases, hemiplegic and diabetic conditions were selected as study samples. Discharge evaluation, follow up home care, measurement and evaluation were carried out according to the protocols of care and measurement plan for each patient for the period of 6 months after discharge. The study was carried out for the period from Jan. 1987 to Dec. 1989. The following are the results of the study presented according to the hypotheses set forth for the study ; 1. Total expenditures for the period of study were not reduced for the experimental group, however, since the cost per hospital visit is about 4 times as great as the cost per home visit, the effect of cost saving by home care will become a reality as home care replaces part of the hospital visits. 2. The effect on the rate of readmission and job retention was found to be statistically nonsignificant though the number of readmission was less among the experimental group receiving home care. 3. The effect on compliance to the health care regime was found to be statistically significant at the 5% level for hepatopathic and diabetic patients. 4. Education on diet, rest and excise, and medication through home care had an effect on improved liver function test scores, prevention of complications and self - care knowledge in hepatopathic patients at a statistically significant level. 5. In hemiplegic patient, home care had an effect on increased grasping power at a significant level. However. there was no significant difference between the experimental and control groups in the level of compliane, prevention of complications or in self-care practices. 6. In diabetic patients, there was no difference between the experimental and control groups in scores of laboratory tests, appearance of complications, and self-care knowledge or self -care practices. The above findings indicate that a home care program instituted for such short term as 6 months period could not totally demonstrate its effectiveness at a statistically significant level by quantitative analysis however, what was shown in part in this analysis, and in the continuous consultation sought by those who had been in the experimental group, is that home health care has a great potential in retarding or preventing pathological progress, facilitating rehabilitative and productive life, and improving quality of life by adding comfort, confidence and strength to patients and their families. For the further studies of this kind with chronic patients it is recommended that a sample of newly diagnosed patients be followed up for a longer period of time with more frequent observations to demonstrate a more dear- cut picture of the effectiveness of home care.

• 대중서사연구
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• 제26권3호
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• pp.123-160
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• 2020

만화는 사회의 변화와 독자들의 요구, 그리고 그들의 생각과 취향의 변화를 항상 민감하게 반영하면서 발전한다. 소녀만화와 여성만화도 마찬가지이다. 2010년대 이후 일본의 여성만화에서는 몇 가지 의미 있는 변화를 찾아볼 수 있다. 로맨스 대신 평범한 일상의 소중함이나 여성의 서사, 자아실현을 그리는 작품이 증가했고 직장 내 성차별, 성희롱 등 민감한 사회 문제를 다루는 작품들도 등장했다. 이전 세대의 만화에서는 쉽게 볼 수 없었던 부분이다. 본 논문에서는 최근작을 중심으로 로맨스가 배제된 서사를 가진 작품과 젠더 문제를 다룬 작품들을 몇 편 선정해 이러한 변화의 사회·문화적 원인을 분석하고 2010년대 일본 여성만화의 변화와 그 의미를 살펴본다. 본 논문에서는 여성 중심의 서사를 통해 소중한 일상을 그린 <바닷마을 다이어리>, 새로운 시선에서 여성의 이야기를 그린 <툇마루에서 모든 게 달라졌다>, 젠더 문제를 정면으로 다룬 <안녕 미니스커트>를 통해 2010년대 여성만화의 흐름을 살펴본다. 그리고 20~30대 여성들에게 인기를 얻은 만화 <나기의 휴식>과 <다루짱>이 동시대 일본 여성의 삶과 고민을 어떻게 재현했는지 집중 분석한다. <나기의 휴식>은 주변 사람들을 지나치게 의식하며 살던 주인공이 모든 것을 버리고 새로운 자아를 찾는 모습을 그렸다. <다루짱> 역시 자아실현과 함께 주인공이 겪는 성희롱과 불평등한 상황을 현실적으로 그리면서 독자들에게 공감대를 형성할 수 있었다. <나기의 휴식>과 <다루짱>은 20대 직장 여성의 고민과 자아실현을 일본 사회의 고유한 현실에 기반해 매우 현실적으로 그린다는 공통점이 있다. 그러나 이들 작품이 특별한 것은 주인공이 하는 고민의 내용과 해결 방법이 이전의 만화들과 다르다는 것이다. 2010년 이후 여성만화의 가장 큰 변화는 현실적인 문제가 사회의 변화와 함께 수면 위로 드러났다는 것이다. 그리고 이러한 모순은 오랜 시간 일본 사회가 안고 있던 불합리한 차별과 구습에 기인한다. 만화는 시대상과 여성상, 가치관을 민감하게 반영한다. 여성만화의 이러한 변화는 곧 당대 독자들의 관심사를 보여주는 것이며 여성들이 문제를 의식하기 시작했다는 의미이기도 하다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권5호
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• pp.2459-2464
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• 2016

Background: Cancer treatments can have long-term physical, psychological, financial, sexual and cognitive effects that may influence the quality of life. These can vary from urban to rural areas, survival period and according to the type of cancer. We here aimed to describe demographics and psychosocial analysis of cancer survivors three to five years post-treatment in rural Australia and also assess relationships with financial stress and quality of life domains. Materials and Methods: In this cross-sectional study, 65 participants visiting the outpatient oncology clinic were given a self-administered questionnaire. The inclusion criteria included three to five years post-treatment. Three domains were investigated using standardised and validated tools such as the Standard Quality of Life in Adult Cancer Survivors Scale (QLACS) and the Personal and Household Finances (HILDA) survey. Included were demographic parameters, quality of life, treatment information and well-being. Results: There was no evidence of associations between any demographic variable and either financial stress or cancer-specific quality of life domains. Financial stress was however significantly associated with the cancer-specific quality of life domains of appearance-related concerns, family related distress, and distress related to recurrence. Conclusions: This unique study effectively points to psychosocial aspects of cancer survivors in rural regions of Australia. Although the majority of demographic characteristics were not been found to be associated with financial stress, this latter itself is significantly associated with distress related to family and cancer recurrence. This finding may be of assistance in future studies and also considering plans to fulfil unmet needs.

• 치위생과학회지
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• 제15권5호
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• pp.636-641
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• 2015

본 연구의 목적은 승무원의 구강건강과 심미적 관심도에 관한 연구로 A항공사에서 근무하는 승무원 314명을 대상으로 2014년 6~7월 동안 자기기입식 설문으로 조사되었다. 사용한 도구는 건강과 구강건강 인식, 구강건강관리, 외적이미지, 외적이미지가 직장생활에 미치는 영향이다. 수집된 자료는 PASW Statistics 18.0을 이용 하여 분석하였다. 연구결과 연령별, 경력별 구강건강 인식에 유의한 차이가 있었고, 교육수준별 삶의 질 인식에 유의한 차이가 있었다. 외적이미지가 직장생활에 미치는 영향은 연령별 유의한 차이가 있었으며, 외모관리 연간 지출비는 성별, 경력별, 소득 집단에서 유의한 차이가 있었다. 승무원은 구강건강이 전신건강보다 건강하지 않다고 인식하고 있어, 외적이미지에 구강건강이 주요한 영향요인이며, 심미증진을 위한 주기적 예방처치 및 심미처치를 시행하고 있었다. 그러나 직무 특성상 구강관리 자가평가가 낮게 조사되어 구강관리 행위 실천을 위한 방안모색이 요구된다. 또한 구강관리가 전신건강을 유지하는데 필수적인 만큼 이에 대한 관심 증대가 요구된다.

• 대한간호학회지
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• 제26권4호
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• pp.759-767
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• 1996

This study was done to provide an understanding of nursing in relation to the existential philosophy of the West and Buddhistic philosophy, It examined how human beings and death are interpreted and understood in existential philosophy as well as in Buddhistic philosophy. Then the study suggested that nursing should focus on helping the sufferer to find meaning and a sense of responsibility in his or her existence. When people have the opportunity to realize certain important but painful truths about their existence, they develop internal strength and control of their lives. Just as people learn to face their being, so can they come to terms with their non-being. According to the causal process in Buddhism, Human Being is not always annihilation of self. Therefore, birth, aging, disease and death go through the process of natural change and it is the appearance of human existence which is inherent in the health of every human being. To promote our health we must gain an insight about this phenomenon. This study viewed nurses' clients as 〈good friend〉 rather than 〈patient〉 which focuses on a disease-oriented concept. The concept of 〈good friend〉 views nurses' clients as active participants to create their life and as responsible persons in a constantly changing life. The study also examined the concept of recovery which means to come back to the previous healthy state and it suggested that the concept of recovery should be changed to 〈good change〉, because in existential philosophy, human beings are viewed as never going back to the past but moving on to the future by creating their existence. This study also suggested that nursing should help 〈good friend〉enlighten their existence to be free from pain and death and to get control over their existence.

• 한방안이비인후피부과학회지
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• 제13권2호
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• pp.140-151
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• 2000

Acne is a common chronic disease which most frequently affects the face, appearing in both males and females near puberty, and in most cases becomes less active as adolescence ends. The intensity and duration of activity vary for each individual. The disease may be minor, with only a few comedones or papules, or it may occur as the highly inflammatory and diffusely scarring acne conglobation. Permanent scarring of the skin and psyche can result from such inaction. The disease, however, has implications far beyond the few marks that may appear on the face. The lesions cannot be hidden under clothing; each is prominently displayed and detracts significantly from one's personal appearance and self-esteem. Recently many of acne patients are visiting to Oriental Medicine Hospitals. They want to receive the treatment of acne related another disease and causes, or worry about side effects of antibiotics and hormone therapy. This study was performed at Pundang Cha Oriental Medicine Hospital Department of Dermatology from March 1, 1997 to February 29, 2000 in 31 patients with recurrent acne. We investigated the clinical findings, included distribution of age & sex, severity of acne, sites on face, related causes, duration of disease and causes of visiting Oriental Medicine Hospital and so on. The results were as follows : The peak age at onset was 20-29 years old in females with 16 cases reported. The 22 total cases patients had severe signs with most frequently sites being forehead & chin. They visited Oriental Medicine Hospital because they want to take the treatment of acne related with another body problems(12 cases) and worry about side effects of antibiotics. Twenty cases were diagnosed 肺熱血熱(20 cases). And given acupuncture treatment, herb-medication and sometimes we used external applications. Relatively, their satisfaction grade was high. Dermatologists are trying to treat new methods in order to remove scar and decrease sebaceous gland secretion,. And we, Oriental Medicine doctors, have to develop and offer to patients the most effective management and successful treatment of this disease.