• Title/Summary/Keyword: selective p-distribution

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Changes in facial surface temperature of laying hens under different thermal conditions

  • Kim, Na Yeon;Kim, Seong Jin;Oh, Mirae;Jang, Se Young;Moon, Sang Ho
    • Animal Bioscience
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    • v.34 no.7
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    • pp.1235-1242
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    • 2021
  • Objective: The purpose of this study was to identify through infrared thermal imaging technology the facial surface temperature (FST) of laying hens in response to the variations in their thermal environment, and to identify the regional differences in FST to determine the most stable and reliable facial regions for monitoring of thermoregulatory status in chickens. Methods: Thirty Hy-Line Brown hens (25-week-old) were sequentially exposed to three different thermal conditions; optimal (OT, 22℃±2℃), low (LT, 10℃±4℃), and high temperature (HT, 30℃±2℃). The mean values of FST in five facial regions including around the eyes, earlobes, wattles, beak and nose, and comb were recorded through infrared thermography. The maximum FST (MFST) was also identified among the five face-selective regions, and its relationship with temperature-humidity index (THI) was established to identify the range of MFST in response to the variations in their thermal environment. Results: Hens exposed to OT condition at 15:00 displayed a higher temperature at wattles and around the eyes compared to other regions (p<0.001). However, under LT condition at 05:00 to 08:00, around the eyes surface temperature showed the highest value (p<0.01). In HT, wattles temperature tended to show the highest temperature over almost time intervals. Main distribution regions of MFST were wattles (63.3%) and around the eyes (16.7%) in OT, around the eyes (50%) in LT, and wattles (62.2%) and comb (18.3%) in HT. The regression equation between MFST and THI was estimated as MFST = 35.37+0.2383×THI (R2 = 0.44; p<0.001). Conclusion: The FST and the frequency of MFST in each facial region of laying hens responded sensitively to the variations in the thermal environment. The findings of this experiment provide useful information about the effect of the thermal conditions on the specific facial regions, thus offering an opportunity to stress and welfare assessment in poultry research and industry.

Lactosaminated N-Succinyl-chitosan: Preparation and Biodistribution into the Intestine, Bone, Lymph Nodes and Male Genital Organs after I.v. Administration

  • Kato, Yoshinori;Onishi, Hiraku;Machida, Yoshiharu
    • Macromolecular Research
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    • v.11 no.5
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    • pp.382-386
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    • 2003
  • Reductive amination of N-succinyl-chitosan (1) and lactose using sodium cyanoborohydride in 1/15 M phosphate buffer (pH 6.0) for 6 d was suitable for the preparation of lactosaminated N-succinyl-chitosan (2). At 8, 24 and 48 h after i.v. administration of fluorescently labeled 1 (1') or 2 (2'), Peyer's patch, mesenteric lymph nodes, testes, prostate, preputial grand, intestine (small intestine plus cecum), femoral muscle, backbone and peritoneum were taken. Peyer's patch and mesenteric lymph nodes were put together as lymph nodes. Over 10% of dose/g tissue was distributed to the prostate and lymph nodes at 48 h post-administration in both l' and 2'.2' was easily distributed into not only the liver but also prostate, intestine, preputial gland and lymph nodes. Although galactose receptors are known to exist not only on the liver parenchymal cells but also on prostate and testes, the selective distribution of 2' into the prostate and the testes were not observed clearly. This study suggested that 1 and 2 should have possibilities for both the prevention and cure of lymph node metastasis as drug carriers.

Selective Removal of Cr (VI) and Cr (III) in Aqueous Solution by Surface Modified Activated Carbon

  • Lee, Jeong-Min;Kim, Min-Il;Lee, Young-Seak
    • Carbon letters
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    • v.9 no.1
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    • pp.23-27
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    • 2008
  • The adsorption and reduction of Cr (VI) to Cr (III) by surface modified activated carbon (AC) in an aqueous solution was studied. The effects of surface modifications on the properties of the carbons were investigated by the analysis of specific surface area, carbon surface pH, acid/base surface values and functional groups. In order to understand the Cr(VI) adsorption and reduction ratio from Cr(VI) to Cr(III), the Cr adsorption capacity of AC was also measured and discussed by using inductively coupled plasma and UV spectrophotometer. The modifications bring about substantial variation in the chemical properties whereas the physical properties such as specific surface area, pore volume and pore size distribution nearly were not changed. Total Cr adsorption efficiency of as-received activated carbon (R-AC) and nitric acid treated activated carbon (N1-AC and N2-AC) were recorded on 98.2, 99.7 and 100%. Cr(III) reduction efficiency of R-AC increased largely from 0.4% to 28.3% compared to N1-AC and N2-AC.

Development of Anti-Melanogenic Agent for Skin Whitening

  • Ahn, Soo-Mi
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 2007.11a
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    • pp.129-139
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    • 2007
  • Many modalities of treatment for acquired skin hyperpigmentation are available including chemical agents or physical therapies, but none are completely satisfactory. The ideal depigmenting compound should have a potent. rapid and selective bleaching effect on hyperactivated melanocytes, carry no short- or long-term side-effects and lead to a permanent removal of undesired pigment. acting at one or more steps of the pigmentation process. Depigmentation can be achieved by regulating (i) the transcription and activity of tyrosinase, tyrosinase related protein-1 (TRP-1), tyrosinase related protein-2 (TRP-2), and/or peroxidase; (ii) the uptake and distribution of melanosomes in recipient keratinocytes and (iii) melanin and melanosome degradation and turnover of pigmented keratinocytes. One of the interesting point for development of skin whitening agent is Mitf(Microphthalmia-associated transcription factor). Mitf belongs to the basic helix-loop-helix-zip family of trabscription factors and it is crucial as it regulates both melanocyte proliferation as well as melanogenesis and is the major regulator of tyrosinase and the related enzymes (TRPs), as well as many melanosome structural proteins such as pMel17. Recently, we developed MITF-down-regulating agents from natural and synthetic sources, which have anti-melanogenic effect on in vitro and in vivo. We suggested that potent MITF-down regulating agents might be used for skin whitening cosmeceuticals.

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Comparison of the Stability Constants of Cd(II)-, Cu(II)-, and Pb(II)-Humate Complexes

  • Choi, Se-Young;Moon, Hi-Chung;Jun, Song-Hui;Chung, Kun-Ho
    • Bulletin of the Korean Chemical Society
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    • v.15 no.7
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    • pp.581-584
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    • 1994
  • A comparative investigation of the complexations of divalent metal ions (Cd, Cu, and Pb) by a well characterized soil humic acid (HA) from Okchun Metamorphic Belt was carried out in 0.05 M $KNO_3$ and pH of 4.5 using ion selective electrodes. A continuous distribution model based on the Scatchard Plot was used to determine the stability constants, because the constants obtained by this modeling technique takes the variations in binding energies into consideration without regards to the manner in which M(II) ion is bound on HA. The mean value of log $K_i$ were $4.05{\pm}0.60,\;4.92{\pm}0.36,\;and\;5.63{\pm}0.34\;{\ell}\;mol^{-1}$ for Cd(II)-, Pb(II), and Cu(II)-humate complexes respectively. The values of intrinsic constant (log $K_{int}$; binding at strongest site) were $7.12{\pm}0.30,\;6.59{\pm}0.32,\;and5.07{\pm}0.56\;{\ell}\; mol^{-1}$ in the order Cu(II) > Pb(II) > Cd(II) ion.

Complexation of Cadmium(Ⅱ) with Soil Fulvic Acid : Effect of pH and Fulvic Acid Concentration (풀빅산과 카드뮴(Ⅱ)과의 착화합 반응 : 풀빅산의 농도와 pH의 영향)

  • Choe, Se Yeong;Jeong, Geun Ho;Jeon, Song Hui;Mun, Hui Jeong
    • Journal of the Korean Chemical Society
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    • v.38 no.8
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    • pp.585-589
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    • 1994
  • The complexation of cadmium(II) with a well characterized local soil fulvic acid was investigated at different solution pH and fulvic acid concentration using ion selective electrode. The stability constants were determined using a continuous distribution model based on Scatchard Plot; this model takes into consideration the diversitv of cation binding sites on a naturally occurring organic macromolecules even if the nature of the binding sites may not be known. The mean value of $logKi(\mu)$ was found to increase at higher pH(pH 4.0: ${\mu}=3.79{\pm}0.74$ l\;mol^{-1}; pH 6.0: ${\mu}=4.51{\pm}0.78$ l\;mol^{-1}$), and in more dilute fulvic acid concentration([FA] = 50 mgl$^{-1}: {\mu}=4.16{\pm}0.60$ l\;mol^{-1}; [FA]=151 mgl$^{-1}:{\mu}=3.75{\pm}0.5\;l\;mol^{-1}$). The intrinsic constant(logKint) for binding at the strongest site was measured to be around $4.72\;l\;mol^{-1}$ at both pH4.0 and 5.0, but was found to be increased to $6.03\;l\;mol^{-1}$ when pH was 6.0.

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Study on the Distribution of Fluorides in Plants and the Estimation of Ambient Concentration of Hydrogen Fluoride Around the Area of the Accidental Release of Hydrogen Fluoride in Gumi (구미 불산 누출사고 지점 주변 식물의 불소화합물 농도 분포 및 공기 중 불화수소 농도 추정에 관한 연구)

  • Gu, Seulgi;Choi, Inja;Kim, Won;Sun, Oknam;Kim, Shinbum;Lee, Yungeun
    • Journal of Environmental Health Sciences
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    • v.39 no.4
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    • pp.346-353
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    • 2013
  • Objectives: The goal of this study is to identify the distribution of the foliar fluorine content of vegetation surrounding the area where hydrofluoric acid was accidently released in Gumi, Gyeongsangbuk-do on September 27, 2012. In addition, it also aims to estimate the concentration of hydrogen fluoride in the air on the day of the accident. Methods: Samples of plant leaves were collected on October 7, 2012 within 1 km from the site where the accident occurred. These samples were analyzed for soluble fluorine ion with an ion selective electrode. The ambient concentration of hydrogen fluoride was calculated using the fluoride content in the plant via the dose-rate equation (${\Delta}F$=KCT). Results: The arithmetic and geometric means of the concentrations were 2158.2 and 1183.7mg F $kg^{-1}$ for leaves and, 2.4 and 1.1 ppm HF for the air, respectively. The highest concentration of hydrogen fluoride in the air was 14.7 ppm, which is higher than the maximum concentration reported by the government (1 ppm) and the exposure limit (ceiling, 3 ppm). The concentrations of both fluorine and hydrogen fluoride decreased with increasing distance from the accident site and showed a significant decrease outside of a 500m radius from the site (p <0.05). Conclusions: The area around the accident site was highly polluted with hydrogen fluoride according to the results of this study. Considering the persistency of hydrogen fluoride in the environment, long-term monitoring and environmental impact assessment should be pursued.

Genetic Variation of H-FABP Gene and Association with Intramuscular Fat Content in Laiwu Black and Four Western Pig Breeds

  • Zeng, Y.Q.;Wang, G.L.;Wang, C.F.;Wei, S.D.;Wu, Y.;Wang, L.Y.;Wang, H.;Yang, H.L.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.1
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    • pp.13-16
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    • 2005
  • This study was performed to detect genetic variation of the heart fatty acid-binding protein (H-FABP) gene by PCRRFLPs approach and its association with intramuscular fat (IMF) content. Data from 223 individuals, including one Chinese native pig breed and four western pig breeds, were analyzed. The results showed that for the H-FABP gene, there was one polymorphic HinfI site in the 5'-upstream region, whereas there were one HaeIII and one HinfI (marked as $HinfI^*$) polymorphic site in the second intron, respectively. The three PCR-RFLPs were present in all breeds tested. The allele frequencies, however, revealed significant differences between them (p<0.05). Furthermore, the allele frequency distribution of HinfI in the Laiwu Black and that of $HinfI^*$ in the Hampshire breed were at disequilibrium, which might be the result of selective breeding. Results also indicated that for HinfI, HaeIII and $HinfI^*$ HFABP RFLP, significant (p<0.05) contrasts of 0.78%, -0.69% and 0.72% were detected in the least square means of IMF content between the homozygous genotype HH and hh, DD and dd, BB and bb classes, respectively. It implied that the HHddBB genotype had the highest IMF content in this experimental population and these H-FABP RFLPs could serve, to some extent, as genetic markers for use in improvement of IMF content.

A Study on Consumer Preference for Plastic Toilet Seats with Selective Automatic Supply of Recycled Water (재활용수의 선택적 자동공급이 가능한 플라스틱류 양변기 소비자 선호도에 관한 연구)

  • Choi, Tae-Wol;Baeg, Jong-Ho;Bae, Sang-Mok
    • Industry Promotion Research
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    • v.5 no.1
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    • pp.13-20
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    • 2020
  • This study is about consumer preference of plastic toilets that can provide automatic supply of recycled water. First, the preference for plastic toilet seat design by gender and age group was preferred for gender type C and G for the sex. As the result of the chi-square test, the significance probability is .044 and the significance is P <.0 5. I could confirm that. Age, teens, 40 s, and 50 s or older prefer type C, 20 s and 30 s, but B type is not statistically significant. Second, the differences among the groups of preference for appearance design criteria according to general characteristics were all stable (stable appearance) in gender, age, region, education, and salary, but the chi-square test showed that they were not statistically significant. There was no difference between them. This study has implications for improving competitiveness and productivity by reducing the main production cost by commercializing toilets made of plastic materials.

Acute Effects of Dynamic Stretching and Self-Mobilization of the Ankle Joint on Dorsiflexion Range of Motion, Muscle Strength, and Balance in Healthy Adults

  • Kim, Kyoung-Han;Choi, Yun-Seo;Jeon, Jeongwoo;Hong, Jihoen;Yu, Jaeho;Kim, Jinseop;Kim, Seong-Gil;Lee, Dongyeop
    • Journal of The Korean Society of Integrative Medicine
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    • v.10 no.3
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    • pp.63-72
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    • 2022
  • Purpose : Several studies have investigated the effects of dynamic stretching (DS) and self-mobilization (SM), however, studies comparing the two interventions are rare. Therefore, the purpose of this study was to compare the effects of DS and SM on ankle strength, dorsiflexion range of motion (DFROM), and balance to determine which is superior. Methods : Thirty-two healthy young adults participated in this study. Participants were randomly assigned to two groups (SM and DS). DS was performed for the purpose of stretching the medial gastrocnemius muscle. For the SM group, ankle joint SM was performed in three ways. For all participants, the following measurements were performed as pre- and post-tests: isometric strength of dorsiflexor and plantar flexor, weight-bearing lunge test (WBLT) to evaluate DFROM, Tetrax system to evaluate static balance, and y balance test (YBT) to evaluate dynamic balance. Differences before and after the intervention within each group were compared using paired t-test. Also, the variable's variation was compared between groups using an independent t-test. Results : Significant differences were found in ankle dorsiflexor strength, WBLT, YBT, weight distribution index (WDI) (pillow and opened eyes; PO), and stability index (ST) (normal and closed eyes; NC) before and after intervention in the SM group (p<.05). In the DS group, significant differences were found in ankle dorsiflexor and plantar flexor strength, WBLT, YBT anterior, WDI (normal and opened eyes; NO, PO), and ST (NO, NC, PO, pillow and closed eyes) before and after the intervention (p<.05). Ankle plantar flexor strength and WDI (PO) were significantly different between groups. Conclusion : Based on the results of this study, DS or SM can be considered as a possibility for selective use according to variables for improving ankle joint function (DFROM, muscle strength, balance).