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Thromboprophylaxis in Abdominoplasty: Efficacy and Safety of a Complete Perioperative Protocol

  • Marangi, Giovanni Francesco;Segreto, Francesco;Poccia, Igor;Campa, Stefano;Tosi, Daniele;Lamberti, Daniela;Persichetti, Paolo
    • Archives of Plastic Surgery
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    • v.43 no.4
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    • pp.360-364
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    • 2016
  • Background Venous thromboembolism, a spectrum of diseases ranging from deep venous thrombosis to pulmonary embolism, is a major source of morbidity and mortality. The majority of cases described in plastic surgery involve abdominoplasty. Risk assessment and prophylaxis are paramount in such patients. General recommendations were recently developed, but the evidence in the literature was insufficient to prepare exhaustive guidelines regarding the medication, dosage, timing, or length of the prophylaxis. Methods A thromboprophylaxis protocol was developed for patients undergoing abdominoplasty. The protocol consisted of preoperative, intraoperative, and postoperative measures. Enoxaparin was administered as chemoprophylaxis in selected patients. The study involved 253 patients. The patients were analyzed for age, body mass index, enoxaparin dosage, risk factors, and complications. Results Deep venous thrombosis was documented in two cases (0.8%). No pulmonary embolism occurred. Three patients (1.2%) presented mild subcutaneous abdominal hematoma within the first postoperative week that spontaneously resorbed with neither aesthetic nor functional complications. Two patients (0.8%) presented severe hematoma requiring surgical re-intervention for drainage and hemostasis revision. Statistical analysis showed no significant correlation between enoxaparin dosage and hematoma (P=0.18) or deep venous thrombosis (P=0.61). Conclusions The described thromboprophylaxis protocol proved to be effective in the prevention of thrombotic events, with an acceptable risk of hemorrhagic complications. Furthermore, it provides new evidence regarding the currently debated variables of chemoprophylaxis, namely type, dosage, timing, and length.

The Surgical Treatment in Type III Acromioclavicular Dislocation Patients Over 45 Years - Primary Clavicular Lateral End Resection Method vs. Conventional Acromioclavicular Joint Reduction Method - (45세 이상의 제 3형 견봉쇄골 관절 탈구 환자의 수술적 치료 - 일차적 쇄골 외측단 절제 술식과 고식적인 견봉쇄골 관절 정복 술식의 비교 -)

  • Moon Eun-Sun;Bae Bong-Hyun;Choi Jin;Kim Myung-Sun
    • Clinics in Shoulder and Elbow
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    • v.8 no.2
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    • pp.88-96
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    • 2005
  • Purpose: To compare and analyze the outcome of primary clavicular lateral end resection method and conventional acromioclavicular (AC) joint reduction method in type III AC dislocation patients over 45 years. Materials and Methods: This study was performed on selected 24 cases of type III AC dislocation patients, over 45 years of age, operated at our hospital from 1998 to 2002. Group I consist of 12 patients who underwent primary clavicular lateral end resection methods (average age: 54.3 years$(45{\sim}72)$). Group II consist of 7 patients using Bosworth methods and 5 patients using Phemister methods (average age: 54.4 years$(45{\sim}71)$). Clinical outcome was evaluated by Weaver and Dunn method. Radiological results were compared by measuring coracoclavicular distance between normal and injured side. Results: As clinical outcome, good was 10 cases(83%); fair 2(17%) in Group I, and good 6(50%); fair 3(25%); poor 3(25%) in Group II. In contrast, the difference of coracoclavicular distance was not statistically significant between two groups before or after surgery, and last follow up. At the last follow up, there was no special correlation between the difference of coracoclavicular distance and clinical outcome. Conclusion: We considered that primary clavicular lateral end resection may be effective for prevention of arthrosis in AC joint in type III AC dislocation patients over 45 years.

A Study of Nasalance Change in Submucosal Type Cleft Palate Patients by Surgery (점막하 구개열 환자의 수술 전후 비음도 변화에 대한 연구)

  • Choi, Ju-Seok;Leem, Dae-Ho;Baek, Jin-A;Kim, Oh-Hwan;Kim, Hyun-Ki;Shin, Hyo-Keun
    • Korean Journal of Cleft Lip And Palate
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    • v.8 no.2
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    • pp.53-62
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    • 2005
  • Submucosal type cleft palate is a kind of cleft palate. A submucosal cleft may result in shortening of the anteroposterior dimension of the hard or soft palates or both. The increased distance along with the lack of muscle connection in the soft palate usually accounts for the lack of palatopharyngeal function in patients with submucosal cleft. Resonance disorders which is found in cleft patients show hypernasality or hyponasality. Many cases of submucosal type cleft palate patients visit our clinics due to hypernasality. In this study, resonance disorders was evaluated through nasalance test. Experimental group was composed of submucosal type cleft palate patients. The patients were treated by a so-called combined therapy, i.e., operation and speech training. To observe the changing pattern by surgery, nasalance test was carried out one time before surgery and three times after surgery. Nasometer II was used as a examination. The questionaire was filled with single vowels & diphthongs. The mean nasalance score of the child was significantly lower than that of the adult at every vowel. An early age at operation (under 10 years) was that a better functional result was achieved with patients. The mean nasalance score of /i/ was highest and that of /a/ was the lowest. The result of corrective surgery in selected cases has achieved improvement in all cases. Hypernasality has been consistently diminished. he operation.

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Related Factors and their Effects on Acute Renal Failure Resulting from Rhabdomyolysis after Pesticide Intoxication (횡문근 융해증이 발생한 농약중독 환자에서 급성 신부전 발생의 연관요인)

  • Kang, Chang-Woo;Lee, Kyung-Woo;Jung, Jin-Hee;Kang, Tae-Shin;Kim, Dong-Hoon;Kim, Sung-Choon;Park, In-Sung
    • Journal of The Korean Society of Clinical Toxicology
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    • v.7 no.2
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    • pp.83-89
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    • 2009
  • Purpose: Rhabdomyolysis is one of the most important complications of pesticide intoxication. It affects a patient's clinical prognosis and can cause acute renal failure. It is important that patients diagnosed with pesticide intoxication receive an accurate initial diagnosis and proper treatment to prevent significant complications. This study's objective was to investigate and confirm related factors causing acute renal failure by verifying clinical observations and laboratory findings collected following pesticide intoxication. Methods: A retrospective analysis was made of 734 patients who presenting to our emergency medical center after ingesting pesticides between January 2006 and December 2008, Of these, 513 patients were selected for the study. Two hundred and twenty-one patients were excluded because of paraquat intoxication, age (if under 18), or chronic renal failure. Seventy-four patients were diagnosed with rhabdomyolysis, based on serum creatinine phosphokinase levels were > 1,000U/L. Acute renal failure was diagnosed when creatinine levels were > 2.0 mg/dL. Results: Among the 74 patients diagnosed with rhabdomyolysis, 26 (35.1%) experienced acute renal failure. The most meaningful related factor in the prediction of acute renal failure was initial arterial pH and creatinine level. Conclusion: Initial arterial pH and creatinine level are predictors of complications such as acute renal failure in patients with rhabdomyolysis.

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Clinical Study on Effect of Ginger Herbal Acupuncture Therapy on Shoulder Pain of Paralytic Patients (생강약침(生薑藥鍼)이 중풍후유증(中風後遺症)으로 인(因)한 견비통(肩臂痛)에 미치는 효과)

  • Heo, Sung-Woong;Kwon, Mi-Jung;Kim, Hong-Gi;Jung, Kyoung-Keun;Kim, Soo-Min;Min, Young-Kwang;Ahn, Chang-Beohm;Song, Choon-Ho;Youn, Hyoun-Min;Jang, Kyung-Jun
    • Journal of Acupuncture Research
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    • v.23 no.5
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    • pp.145-154
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    • 2006
  • Objectives : The purpose of this research is to study the effect of Ginger-Herbal acupuncture on shoulder pain of cerebral paralytic patients. Methods : 53 person were selected among patients hospitalized in Dong-eui Oriental medical hospital from 1st, May, 2005 to 1st, Oct, 2005. They were divided into two groups, i.e acupuncture group and ginger-herbal acupuncture group. For 2 weeks, 22 patients were treated by ginger-herbal acupuncture treatments and 31 patients were treated by only acupuncture treatments. Research tools are Visual Analogue Scale by Cline et al. for measuring the severity of shoulder pain, and measured Range of Movement of shoulder joint Results : The ginger-herbal acupuncture treatments group showed significant pain decrease while acupuncture treatments group showed pain decrease. The range of shoulder movement was not significantly improved in both 2 groups. Conclusion : Based on the above results, it can be determined that ginger-herbal acupuncture therapy can be used as the effective treatments for reducing of shoulder pain. But more cases are to be studied in order to make more effective treatments in the case of shoulder pain of paralytic patients.

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Assessment of Treatment Outcome after Using Temporary Mandibular Advancement Devices in Obstructive Sleep Apnea Patients (폐쇄성 수면 무호흡 환자에서 임시 하악 전방 이동 장치를 이용한 치료결과 분석)

  • Park, Joon-Hyung;Oh, Suseok;Hong, Jongrak;Kim, Chang-Soo;Paeng, Jun-Young
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.34 no.6
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    • pp.426-431
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    • 2012
  • Purpose: The aim of this study was to evaluate the effect of temporary mandibular advancement devices (MAD) in obstructive sleep apnea (OSA) patients Methods: 28 patients (male 21, female 7) undergoing temporary mandibular advancement device treatment for OSA were selected from 2011.01. to 2012.02. in the department of Oral & Maxillofacial Surgery at SamsungMedicalCenter. Treatment efficacy was determined by polysomnography (PSG) at baseline & after MAD delivery. The response group was defined as >50% Apnea-Hypopnea Index (AHI) reduction plus post-MAD AHI <10, and the non-response group was defined as <50% AHI reduction. The lateral cephalogram was analysed including SNA, SNB, UL, MPH, PAS, PASU, and PAST using V-ceph$^{TM}$ (Cybermed, USA). Results: The responsers were 23 patients, and non-responsers were 5 patients. The AHI was significantly reduced with temporary MAD ($8.08{\pm}7.93$) compared with baseline ($28.51{\pm}20.56$) in the response group (n=23). No significant difference was observed between pre MAD and post MAD except SNB on cephalometric analysis. Among 11 patients successfully treated with the temporary device, 9 patients said that using permanent device brings better effect too. Conclusion: These results indicate that the Temporary MAD could not be the only effective tools on OSA but also be used to predict patient's reactivity about permanent appliance treatment. Further studies are warranted to evaluate the relations between temporary MAD and permanent MAD.

A Study on Characteristics of Skin Resistance Variability(SRV) in the Traffic Accident Patients Prescribed Dangkisoo-san(Dangguixu-san) (당귀수산을 처방받은 교통사고환자의 피부저항변이도 특성에 관한 연구)

  • Kim, Eu-Gene;Cha, Yun-Yeop
    • Journal of Korean Medicine Rehabilitation
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    • v.18 no.3
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    • pp.119-132
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    • 2008
  • Objectives : The purpose of this study was to know the characteristics of Skin Resistance Variability(SRV) in the traffic accident patients prescribed Dangkisoo-san(Dangguixu-san). Methods : 65 traffic accident patients were selected from those who took the Skin Resistance Variability(SRV) test in Oriental Medical Hospital of Sang-Ji University from March 2007 to January 2008. The traffic accident patients were prescribed Dangkisoo-san(Dangguixu-san). Mean values of factor AA on skin resistance variability of the traffic accident patients were analyzed. Results and Conclusions : The mean values of electrodermal activity of preexamination was higher than those of postexamination in all areas except 3 area in 2nd measurement. In most cases, the gap of electrodermal activity between preexamination and postexamination within the female group was higher than those of the male group. In most cases, the gap of electrodermal activity between preexamination and postexamination within the more than 21 days group was higher than those of the 20days and less group. In most cases, the gap of electrodermal activity between preexamination and postexamination within the 36 years old group was higher than those of the 35years old and less group. Dangkisoo-san(Dangguixu-san) will be more effective for acute and strong traffic accident patients than chronic and weak traffic accident patients. So, further studies will be needed.

Study on the Prescribed Doses and Dispensing Patterns of Warfarin and Digoxin Tablets (Warfarin 및 Digoxin 정제의 처방 용량 실태 및 조제 양식의 고찰)

  • Kim, Yoonsook;Lee, Seungmi;Chun, Pusoon
    • YAKHAK HOEJI
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    • v.58 no.1
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    • pp.40-46
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    • 2014
  • Drugs with a narrow therapeutic index (NTI) require very precise dosing. Warfarin and digoxin are the examples of NTI-drugs and dosing of them varies widely for different patients. However, in South Korea, only two strengths of warfarin and one of digoxin are commercially available. This is a big barrier for the precise dispensing and has potential safety risks to patients, particularly to elderly patients. To find a potential solution to the problem, an analysis of the prescribed doses and dispensing patterns of those drugs was performed. Data were collected by computer-facilitated prescription review in a university hospital. The period screened was from May 1st, 2012 to April 30th, 2013. All the prescriptions with either warfarin or digoxin tablets were selected for this study and dispensing patterns were analyzed according to the prescribed doses. A total of 17,017 warfarin prescriptions were analyzed; 8,148 for inpatient prescriptions, 8,869 for outpatient prescriptions, respectively. Of the 23 kinds of prescribed doses, 2 mg (19.9%) was most frequent, followed by 3 mg (13.2%) and 2.5 mg (11.7%). By analyzing the dispensing patterns, 60.3% (10,253) of the prescriptions required pill splitting and 72.0% of them were for the patients 65 years old and over. On the other hand, 4,350 digoxin prescriptions were included in this study. Of the 6 kinds of prescribed doses, 0.125 mg (71.2%) was most frequent, followed by 0.0625 mg (20.2%). Among the prescriptions for digoxin, 92.0% (3,998) should be split and 65.7% of them were for the patients aged 65 years and over. Despite limitations of strengths, various doses of warfarin and digoxin were prescribed. Furthermore, more than half of the prescriptions that required pill splitting were for elderly patients. The results from this study suggest that different strengths of warfarin and digoxin should be provided for accuracy of dispensing and safety for patients receiving them.

Shifting of Centricity: Qualitative Meta Synthetic Approach on Caring Experience of Family Members of Patients with Dementia (중심성의 이동: 치매 환자 가족의 돌봄 경험에 대한 질적 합성 접근)

  • Ryu, Young Mi;Yu, Mi;Oh, Seieun;Lee, Haeyoung;Kim, Haejin
    • Journal of Korean Academy of Nursing
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    • v.48 no.5
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    • pp.601-621
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    • 2018
  • Purpose: This study aimed to synthesize the caring experiences of Korean family members of patients with dementia through a qualitative meta-synthesis method. Methods: By searching through nine Korean and English databases, we compared 37 qualitative studies on caring experiences of family members of patients with dementia. The selected studies were synthesized through meta-synthesis, proposed by Sandelowski and Barroso (2007). Results: The meta-synthesis elicited four themes: tough life due to care for patients, changes in relationships, adaptation to caregiver's roles, and new perspectives of life through personal growth. Caregivers were shocked when a sudden diagnosis of dementia was made prior to any preparation on their part. They were tied to their patients all the time and their mind and body got exhausted. Their relationship with patients began to change and they looked at them differently. They experienced conflicts with the other non-caring family members and were alienated from them. They were also socially isolated. However, by building their own care strategies and utilizing social resources, they gradually adapted to their caregiver roles. Finally, they experienced personal growth and acquired a new perspective toward life by accepting their roles and finding meaning in their lives. Shifting the caregiver's centricity from themselves to the patient was the process of becoming human beings who actively constructed their realities while giving meaning to their painful lives and interacting with the environment. Conclusion: The results of the study can be useful for nurses in understanding the experiences of caregivers of the patients with dementia and in providing them with practical interventions.

Comparison of Upper and Lower Trapezius Activity During Shoulder Elevation and Depression for Acute and Chronic Whiplash-associated Disorder Patients (급성과 만성 편타성-관련 손상 환자의 상지 거상과 하강 동작시 상승모근과 하승모근의 근활성도 비교)

  • Kim, Sang-Su;Kim, Suhn-Yeop
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.16 no.1
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    • pp.26-36
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    • 2010
  • Purpose: The study compared the muscle activity and ratio of upper trapezius (UT) to lower trapezius (LT) activity between acute and chronic whiplash-associated disorder (WAD) patients. Methods: Twelve healthy (male: 7), 14 acute WAD (male: 7), and 11 chronic WAD (male: 3) volunteers participated in this study. Electromyography using a surface EMG recorded the activity of the upper trapezius and lower trapezius of both shoulders (dominant and non-dominant) during $120^{\circ}$ elevation when standing and shoulder depression when sitting. The testing order was selected randomly. Subjects were asked to maintain each experimental position for 5 seconds at end range. EMG activity was normalized using the maximal voluntary isometric contraction (MVIC) elicited using a manual muscle-testing technique. One-way repeated measures analysis of variance (ANOVA) was used to compare the average root mean square (RMS) value of EMG activity for each condition. Results: The EMG activity of the dominant UT for chronic WAD subjects was significantly higher than for acute WAD subjects during $120^{\circ}$ elevation (p<.05). The EMG activity of the dominant LT for acute WAD subjects was significantly lower than for the control group (p<.05) during $120^{\circ}$ elevation. The EMG activity of the dominant LT for WAD patients was significantly lower than for the control group during shoulder depression (p<.05), and the chronic WAD patients scored significantly the lowest (p<.01). The dominant UT/LT for chronic WAD patients was significantly higher than the ratio for acute WAD subjects during shoulder depression (p<.05); this result was higher than for the control group (p<.01). The non-dominant UT/LT (ratio) for chronic WAD patients was significantly higher than the ratio for acute WAD subjects during shoulder depression (p<.05). Conclusion: The UT for chronic WAD subjects was hyperactive when compared to the acute WAD subjects, and the was hypoactive for both acute and chronic patients, therefore intra-trapezius imbalance was more prevalent during shoulder depression.

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